Catalog No.
Product Name
Application
Product Information
Citations
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Fluorescent Dye
BODIPY 581/591 C11 is a boron-dipyrromethene (BODIPY) derivative with excellent photostability and minimal fluorescence artifacts. It is widely used to study lipid peroxidation and antioxidant activity in living cells, and to detect ferroptosis through its reaction with hydroxyl radicals. The dye exhibits a fluorescence shift upon oxidation: the reduced form emits at 591 nm (Ex: 581 nm), while the oxidized form emits at 510 nm (Ex: 500 nm). -
Mitochondrial Membrane Potential Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by sensing mitochondrial membrane potential, resulting in bright fluorescence. Due to their low cytotoxicity at appropriate concentrations, they are widely used for mitochondrial labeling in animal cells, plant cells, and microorganisms. -
Fluorescent Probe
DiO is a long-chain carbocyanine dye commonly used for labeling cells, organelles, liposomes, viruses, and lipoproteins. As a member of the Di-series carbocyanine dyes, DiO integrates into lipid membranes, enabling effective fluorescent tracking in various biological systems. -
fluorescent probe
RhoNox-1 is a fluorescent probe designed for the specific detection of divalent iron ions (Fe²⁺). Upon reaction with Fe²⁺, RhoNox-1 forms an irreversible orange-red fluorescent product (Ex/Em: 540/575 nm). It efficiently penetrates cell membranes and is suitable for detecting intracellular Fe²⁺, with a tendency to localize in the Golgi apparatus. - Calcein AM is a cell-permeable, non-fluorescent dye that readily enters live cells. Once inside, it is hydrolyzed by intracellular esterases to generate Calcein, a polar and highly negatively charged molecule that is retained within the cytoplasm. Calcein emits strong green fluorescence (Ex/Em: 494/515 nm) and is commonly used in combination with Propidium Iodide for assessing cell viability and cytotoxicity.
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Fluorescent Probe
Laurdan is a membrane-permeable fluorescent probe that exhibits spectral sensitivity to the phospholipid phase of the membrane it integrates into. Measurement of its generalized polarization (GP) enables quantification and distinction of membrane phases, such as liquid-ordered and liquid-disordered states. -
Mitochondrial Membrane Potential Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by recognizing mitochondrial membrane potential, producing bright fluorescence. At appropriate concentrations, they exhibit low cytotoxicity and are widely used for mitochondrial staining in animal cells, plant cells, and microorganisms. -
Fluorescent Dye
BODIPY-cholesterol is a lipophilic, cell-permeable fluorescent analog of cholesterol, labeled with a BODIPY fluorophore (Ex/Em: 505/515 nm). It is commonly used to monitor sterol uptake, distribution, and inter-organelle trafficking in live cells. -
Fluorescent Dye
Coppersensor-1 (CS1) is a membrane-permeable fluorescent probe with picomolar affinity for Cu⁺ ions, exhibiting high selectivity over other cellular metal ions. It enables sensitive and selective detection of copper(I) in biological samples, including live cells. CS1 is suitable for imaging studies related to copper homeostasis in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. -
Red Fluorescent Dye
FM4-64 is a highly lipophilic, water-soluble styryl dye that selectively binds to the plasma membrane and internal membrane-bound organelles, producing bright fluorescence. It is widely used as a marker for endocytic and exocytic membrane structures in live-cell imaging studies. -
Fluorescent Dye
CellTracker Blue CMAC is a non-fluorescent, cell-permeable dye that becomes fluorescent upon enzymatic conversion by intracellular glutathione (GSH). The chloromethyl groups are cleaved to yield a blue fluorescent product (Ex/Em: 360/460 nm). It is suitable for long-term cell tracking (up to 72 hours), cell proliferation studies, and quantification of intracellular GSH levels. -
Fluorescent Probe
DiSC3(5) is a fluorescent probe commonly used to assess mitochondrial membrane potential, with excitation/emission maxima at 622/670 nm. It can inhibit mitochondrial NAD-linked respiratory activity, with an IC₅₀ of 8 μM. In the presence of the Na⁺/K⁺-ATPase inhibitor ouabain, DiSC3(5) induces membrane hyperpolarization in Ehrlich ascites tumor cells. -
Red Fluorescent Dye
MitoTracker Deep Red FM is a fluorescent dye that selectively accumulates in the mitochondrial matrix and covalently binds to mitochondrial proteins by reacting with free thiol groups of cysteine residues. This allows for stable mitochondrial labeling independent of membrane potential. The dye has excitation/emission maxima at 644/665 nm. Store protected from light. -
Cell Death Indicator
LysoTracker Red is a red-fluorescent lysosomal probe with excitation/emission maxima at 577/590 nm. It consists of a fluorophore linked to a weakly basic moiety, allowing it to freely cross cell membranes and selectively accumulate in acidic organelles such as lysosomes. LysoTracker Red is commonly used for visualizing lysosomal structures and studying lysosome-related biosynthesis and pathogenesis. -
Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by recognizing mitochondrial membrane potential. They generate bright fluorescence upon localization and exhibit low cytotoxicity at appropriate concentrations. Rhodamine dyes are widely used for mitochondrial staining in animal cells, plant cells, and microorganisms. -
Fluorochrome
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe developed for the selective detection and quantification of hydrogen peroxide in the presence of various reactive nitrogen and oxygen species (RNOS). For nearly two decades, DPBF has been widely used as a specific indicator for reactive oxygen species, particularly singlet oxygen, hydroxyl radicals, alkoxyl radicals, and alkylperoxy radicals. -
RNA Aptamers Probe
DFHBI-1T is a membrane-permeable fluorescent probe activated by RNA aptamers, with excitation/emission maxima at 472/507 nm. It specifically binds to aptamers such as Spinach, Spinach2, iSpinach, and Broccoli, resulting in bright fluorescence with low background signal. DFHBI-1T is commonly used for live-cell imaging of RNA. -
DNA Fluorescent Stain
Hoechst 33342 trihydrochloride is a cell-permeable fluorescent dye from the Hoechst series, widely used as a live-cell nuclear marker. It binds preferentially to the minor groove of A/T-rich regions in double-stranded DNA, resulting in enhanced fluorescence intensity. Although it can associate with various nucleic acids, its fluorescence is significantly stronger upon binding to A/T-rich DNA. Hoechst 33342 is suitable for labeling live cells, and its fluorescence intensity increases with rising solution pH. -
Fluorescent dye
Rhodamine B is a fluorescent dye widely used for staining applications. It is commonly employed in the dyeing of textiles, paper, soap, leather, and various industrial agents. -
Endoplasmic Reticulum Fluorescent Dye
ER-Tracker dye is a BODIPY-based fluorescent probe conjugated with Glibenclamide, exhibiting high selectivity for the endoplasmic reticulum (ER). It is cell-permeable, non-toxic at low concentrations, and retains partial fluorescence after formaldehyde fixation. As an environment-sensitive dye, R-Tracker offers a long fluorescence lifetime and a high extinction coefficient. Glibenclamide, an ATP-sensitive K⁺ channel (Kir6.x, KATP) and CFTR Cl⁻ channel blocker, mediates ER targeting. R-Tracker is not suitable for post-fixation staining. -
Membrane Dye
DiR is a long-chain carbocyanine dye commonly used for labeling and tracking biological structures. As a member of the Di series of dyes, DiR is particularly suited for labeling cells, organelles, liposomes, viruses, and lipoproteins due to its strong membrane affinity and near-infrared fluorescence properties. -
Fluorescent Dye
IR780 is a prototypic near-infrared (NIR) heptamethine cyanine dye with a high molar extinction coefficient. It exhibits a maximum excitation wavelength of 777–780 nm and a maximum emission wavelength of 798–823 nm. IR780 is widely used in cancer research for photothermal therapy (PTT), photodynamic therapy (PDT), and imaging applications. -
Luciferin analogue
AkaLumine hydrochloride is a luciferin analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. It is commonly used in bioluminescence imaging and reporter assays for enhanced sensitivity and signal stability. -
Mitochondrial Dye
MitoTracker Green FM is a green fluorescent dye that selectively targets the mitochondrial matrix. It covalently binds to mitochondrial proteins through reaction with free mercaptan groups on cysteine residues, facilitating the visualization of mitochondrial structures independently of membrane potential. This dye is widely utilized in cellular and molecular biology research to study mitochondrial dynamics, function, and viability. Excitation and emission wavelengths are 490 nm and 523 nm, respectively. -
Green Fluorescent Dye
PKH 67 is a green fluorescent dye primarily used for staining cell membranes. With an excitation/emission range of 490/502 nm, it enables precise labeling of cells to facilitate studies of cell proliferation in vitro and tracking of cells in both in vitro and in vivo environments. This dye is commonly employed alongside the non-specific red fluorescent dye PKH26 to enhance multi-color cell analysis. -
Cellular Zinc Fluorescent Sensor
TSQ is a membrane-permeable fluorescent probe designed for the detection of zinc ions within cells, specifically targeting the cytosolic compartment. It exhibits a fluorescence emission maximum at approximately 495 nm when excited at 334 nm, enabling effective intracellular imaging of zinc-containing proteins. TSQ forms a complex with Zn2+ in the presence of Ca2+ and Mg2+, resulting in a distinctive blue fluorescence signal, making it a valuable tool for research applications involving cellular zinc dynamics and metalloprotein studies. -
Diazol Dye
Oil Red O is a fat-soluble diazol dye that primarily targets neutral lipids and cholesteryl esters, exhibiting maximum absorption at 518 nm. This reagent is widely utilized for the detection and quantification of hepatic steatosis in mouse liver biopsies, allowing for the visualization of significant metabolic changes in tissues. Oil Red O staining serves as an essential tool for researchers studying metabolic diseases and their progression. -
Fluorescent Dye
Thiazole Orange is a fluorescent dye primarily designed for nucleic acid detection. It exhibits significant fluorescence enhancement upon binding to DNA and RNA, making it ideal for applications such as biomolecular detection, gel staining, and reticulocyte analysis. This dye permeates living cell membranes and can be detected using ultraviolet or blue light, with an excitation maximum at 510 nm (also excitable at 488 nm and 470 nm) and an emission maximum at 527 nm. -
Fluorescent Probe
Acridine Orange 10-Nonyl Bromide is a fluorescent probe primarily targeting cardiolipin. This compound exhibits excitation maximum at 489 nm and emission maximum at 525 nm, making it suitable for studies involving mitochondrial function and apoptosis. It is widely used in various biological research applications, particularly in understanding membrane dynamics and cellular lipid interactions. -
Dye
Cyanine7 NHS ester tetrafluoroborate is a near-infrared fluorescent dye designed for biological conjugation applications. It exhibits strong fluorescence properties, making it ideal for imaging and labeling studies in fluorescence microscopy and flow cytometry. This reagent is particularly useful in labeling proteins and other biomolecules for enhanced visualization in various research contexts. -
Lipid Peroxidation Fluorescent Probe
LPd peroxida probe is a fluorescent marker specifically designed to detect lipid peroxidation, a key process in ferroptosis. This probe effectively converts lipid hydroperoxides into lipid alcohols, facilitating the imaging of lipid hydroperoxides in live cells. It is an invaluable tool for researchers exploring the implications of lipid peroxidation in various cellular pathophysiologies. -
Fluorescent Dye
Sulfo-Cy5-N3 is a versatile fluorescent dye featuring an azide group that enables its use in click chemistry applications. Primarily utilized for imaging, this red fluorescent label (Excitation/Emission=642/670 nm) facilitates the visualization of biomolecules through the copper-catalyzed azide-alkyne cycloaddition (CuAAc) method when paired with alkyne-containing compounds. Additionally, it can participate in the ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it suitable for a variety of biological and chemical research applications. -
Fluorescent Dye
Sulfo-CY-5.5 NHS ester tripotassium is an amine-reactive ester derived from the sulfonated far-red fluorophore, Cyanine5.5. This reagent is utilized for labeling antibodies and proteins, enabling effective detection in various biological assays. Additionally, it is suitable for in vivo near-infrared imaging applications, facilitating enhanced visualization in biological research. -
Fluorescent Dye
Fura Red AM is a fluorescent dye specifically designed for visualizing Ca2+ distribution within the cytoplasm of undifferentiated cells. This probe exhibits optimal excitation at 488 nm, making it suitable for various fluorescence microscopy applications. Fura Red AM is essential for studies exploring calcium signaling and cellular dynamics in live cell imaging. -
Dye
TAMRA-PEG3-Azide is a fluorescent dye derivative of TAMRA featuring three polyethylene glycol (PEG) units. This compound contains an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalities. TAMRA-PEG3-Azide is valuable for applications in fluorescent labeling and bioconjugation in chemical biology research. -
Fluorescent Dye
AF647-NHS ester triTEA is a fluorescent dye with an excitation wavelength of 635 nm, suitable for conventional fluorescence detection, and 620 nm for instantaneous detection. The NHS ester functionality enables covalent binding to amine-containing molecules, including proteins and antibodies, facilitating targeted labeling. This reagent is ideal for a variety of applications in fluorescence microscopy, flow cytometry, and other research techniques requiring precise visualization of biomolecules. -
Fluorescent Dye
Fluorescamine is a spirocyclic compound that serves as a fluorescent dye targeting primary amine groups. Under alkaline conditions, it rapidly reacts with these groups in proteins, resulting in highly fluorescent products with an excitation/emission maximum of 390/475 nm. This reagent is particularly useful for the detection of amine-containing compounds, such as amino acids, peptides, and proteins, and is widely utilized in biochemical assays and analytical techniques. -
Dye
TAMRA-Azide-PEG-biotin is a dye derivative that incorporates an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN modified compounds. This reagent is valuable for labeling and tracking biomolecules in various biological assays, enhancing visualization and detection in chemical biology research. -
Fluorescent Dye
BODIPY-FL is a green fluorescent dye primarily utilized for labeling biological probes and primers. It exhibits unique fluorescence quenching capabilities upon interaction with specific guanine positioning, making it effective for quantifying particular DNA or RNA molecules. With a maximum absorption wavelength of 505 nm and an emission wavelength of 513 nm, BODIPY-FL is a valuable tool in nucleic acid detection and analysis applications. -
Fluorescent Dye
Cy5.5-COOH is a fluorescent dye that emits light at 710 nm when excited at 650 nm. This compound features outstanding spectral characteristics, including a narrow absorption spectrum, high sensitivity, and exceptional stability. Cy5.5-COOH is ideal for applications in bioimaging and disease diagnosis, facilitating precise visualization and analysis in research settings. -
Cationic Copper Phthalocyanine Dye
Alcian Blue 8GX is a cationic copper phthalocyanine dye that binds specifically to glycoproteins and glycosaminoglycans. This reagent is widely utilized in biological staining applications, facilitating the visualization of proteins in brain tumors as well as DNA in various cells and tissues. Its robust staining capability makes it an essential tool for histological and cytological analyses. -
Fluorescent Dye
DAPI dilactate is a potent fluorescent dye primarily known for its strong binding affinity to DNA, specifically targeting the AT base pairs in the minor groove of double-stranded DNA. This binding significantly enhances fluorescence intensity, making it a valuable tool for applications in fluorescence microscopy to quantify DNA based on fluorescence signals. While DAPI is effective for staining both live and fixed cells, it does not penetrate intact cell membranes. Additionally, DAPI serves as an inhibitor of acid-sensing ion channel 3 (ASIC3), blocking its function, and is useful in research focused on chronic pain treatments (Ex/Em = 356/451 nm). -
Fluorescent Dye
BODIPY TR Cadaverine is a cadaverine derivative that functions as a red fluorescent dye. It is specifically designed for use in sensitive fluorescent displacement assays, effectively binding to native lipopolysaccharides (LPS) with high specificity for lipid A. This compound can be competitively displaced by agents that exhibit affinity for lipid A, making it a valuable tool in research applications involving bacterial LPS interactions and membrane studies. -
H2S Fluorescent Dye
WSP-1 is a selective fluorescent dye designed for the specific detection of hydrogen sulfide (H2S), exhibiting excitation and emission maxima at 465 nm and 515 nm, respectively. Upon reaction with H2S, WSP-1 produces a distinct fluorescent signal through the release of its fluorophore. This property makes WSP-1 a valuable tool in biochemical research for monitoring H2S levels in biological samples and studying its physiological roles. -
Fluorescent Tracer
Fluorescein sodium is a prominent fluorescent tracer employed in various medicinal and biological applications, particularly for imaging tumor-infected tissues. As a well-established green fluorophore, it serves as a foundational scaffold for the development of effective green fluorescent probes, enabling enhanced visualization and tracking in research studies. This compound's versatility makes it an essential tool for fluorescence microscopy and related imaging techniques. -
Fluorescent Dye
CY3 (Sulfo-Cyanine3) is a fluorescent dye characterized by its orange emission (λex=554, λem=568). This dye is widely utilized for labeling proteins and nucleic acids in various biological assays. Its strong fluorescent properties make it an ideal choice for applications in fluorescence microscopy, flow cytometry, and in situ hybridization. CY3 facilitates the visualization and analysis of molecular interactions within complex biological systems. -
Fluorescent Dye
Cy5.5 is a cyanine fluorescent dye known for its long-wavelength absorption and emission properties. It features a high extinction coefficient and good water solubility, making it suitable for a variety of biological applications. Cy5.5 is commonly utilized for the labeling of proteins, antibodies, and small molecules, facilitating applications such as fluorescence microscopy, flow cytometry, and in vivo imaging. The straightforward labeling process through simple mixing reactions enhances its utility in various research settings. -
Reactive Dye
CY5 is a reactive dye that belongs to the Cyanine family, characterized by its long wavelength absorption and emission properties. Its high extinction coefficient and excellent water solubility make it ideal for bioconjugation applications. Commonly utilized for labeling proteins, antibodies, and small molecular compounds, CY5 enables efficient visualization and tracking in various biological assays. The labeling process can be performed through a straightforward mixing reaction, facilitating its use in diverse research settings. -
Reactive Dye
CY5-SE (Cy5 NHS Ester) is a reactive dye specifically designed for the labeling of amino groups in peptides, proteins, and oligonucleotides. This reagent facilitates efficient labeling reactions in the presence of minimal organic co-solvents, such as DMF or DMSO. CY5-SE is particularly suitable for cost-effective labeling of soluble proteins, peptides, and oligonucleotides, as well as for labeling small molecules in organic solvents. With an excitation wavelength of 649 nm and an emission wavelength of 670 nm, this dye is valuable for a range of fluorescence-based assays and applications in biochemical research. -
Fluorescent Dye
HaloTag TMR is a red fluorescent dye designed for the specific labeling of HaloTag proteins. This compound consists of HaloTag ligand molecules conjugated with TMR (TAMRA), allowing for rapid and stable covalent binding with high specificity and affinity. With excitation and emission wavelengths of 550 nm and 576 nm, respectively, it is ideal for a range of biological applications, including live-cell imaging and protein localization studies.
