Catalog No.
Product Name
Application
Product Information
Citations
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Fluorescent Dye
Sulfo-CY-5.5 NHS ester tripotassium is an amine-reactive ester derived from the sulfonated far-red fluorophore, Cyanine5.5. This reagent is utilized for labeling antibodies and proteins, enabling effective detection in various biological assays. Additionally, it is suitable for in vivo near-infrared imaging applications, facilitating enhanced visualization in biological research. -
Fluorescent Dye
Fura Red AM is a fluorescent dye specifically designed for visualizing Ca2+ distribution within the cytoplasm of undifferentiated cells. This probe exhibits optimal excitation at 488 nm, making it suitable for various fluorescence microscopy applications. Fura Red AM is essential for studies exploring calcium signaling and cellular dynamics in live cell imaging. -
Dye
TAMRA-PEG3-Azide is a fluorescent dye derivative of TAMRA featuring three polyethylene glycol (PEG) units. This compound contains an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalities. TAMRA-PEG3-Azide is valuable for applications in fluorescent labeling and bioconjugation in chemical biology research. -
Fluorescent Dye
AF647-NHS ester triTEA is a fluorescent dye with an excitation wavelength of 635 nm, suitable for conventional fluorescence detection, and 620 nm for instantaneous detection. The NHS ester functionality enables covalent binding to amine-containing molecules, including proteins and antibodies, facilitating targeted labeling. This reagent is ideal for a variety of applications in fluorescence microscopy, flow cytometry, and other research techniques requiring precise visualization of biomolecules. -
Fluorescent Dye
Fluorescamine is a spirocyclic compound that serves as a fluorescent dye targeting primary amine groups. Under alkaline conditions, it rapidly reacts with these groups in proteins, resulting in highly fluorescent products with an excitation/emission maximum of 390/475 nm. This reagent is particularly useful for the detection of amine-containing compounds, such as amino acids, peptides, and proteins, and is widely utilized in biochemical assays and analytical techniques. -
Dye
TAMRA-Azide-PEG-biotin is a dye derivative that incorporates an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN modified compounds. This reagent is valuable for labeling and tracking biomolecules in various biological assays, enhancing visualization and detection in chemical biology research. -
Fluorescent Dye
BODIPY-FL is a green fluorescent dye primarily utilized for labeling biological probes and primers. It exhibits unique fluorescence quenching capabilities upon interaction with specific guanine positioning, making it effective for quantifying particular DNA or RNA molecules. With a maximum absorption wavelength of 505 nm and an emission wavelength of 513 nm, BODIPY-FL is a valuable tool in nucleic acid detection and analysis applications. -
Fluorescent Dye
Cy5.5-COOH is a fluorescent dye that emits light at 710 nm when excited at 650 nm. This compound features outstanding spectral characteristics, including a narrow absorption spectrum, high sensitivity, and exceptional stability. Cy5.5-COOH is ideal for applications in bioimaging and disease diagnosis, facilitating precise visualization and analysis in research settings. -
Cationic Copper Phthalocyanine Dye
Alcian Blue 8GX is a cationic copper phthalocyanine dye that binds specifically to glycoproteins and glycosaminoglycans. This reagent is widely utilized in biological staining applications, facilitating the visualization of proteins in brain tumors as well as DNA in various cells and tissues. Its robust staining capability makes it an essential tool for histological and cytological analyses. -
Fluorescent Dye
DAPI dilactate is a potent fluorescent dye primarily known for its strong binding affinity to DNA, specifically targeting the AT base pairs in the minor groove of double-stranded DNA. This binding significantly enhances fluorescence intensity, making it a valuable tool for applications in fluorescence microscopy to quantify DNA based on fluorescence signals. While DAPI is effective for staining both live and fixed cells, it does not penetrate intact cell membranes. Additionally, DAPI serves as an inhibitor of acid-sensing ion channel 3 (ASIC3), blocking its function, and is useful in research focused on chronic pain treatments (Ex/Em = 356/451 nm). -
Fluorescent Dye
BODIPY TR Cadaverine is a cadaverine derivative that functions as a red fluorescent dye. It is specifically designed for use in sensitive fluorescent displacement assays, effectively binding to native lipopolysaccharides (LPS) with high specificity for lipid A. This compound can be competitively displaced by agents that exhibit affinity for lipid A, making it a valuable tool in research applications involving bacterial LPS interactions and membrane studies. -
H2S Fluorescent Dye
WSP-1 is a selective fluorescent dye designed for the specific detection of hydrogen sulfide (H2S), exhibiting excitation and emission maxima at 465 nm and 515 nm, respectively. Upon reaction with H2S, WSP-1 produces a distinct fluorescent signal through the release of its fluorophore. This property makes WSP-1 a valuable tool in biochemical research for monitoring H2S levels in biological samples and studying its physiological roles. -
Fluorescent Tracer
Fluorescein sodium is a prominent fluorescent tracer employed in various medicinal and biological applications, particularly for imaging tumor-infected tissues. As a well-established green fluorophore, it serves as a foundational scaffold for the development of effective green fluorescent probes, enabling enhanced visualization and tracking in research studies. This compound's versatility makes it an essential tool for fluorescence microscopy and related imaging techniques. -
Fluorescent Dye
CY3 (Sulfo-Cyanine3) is a fluorescent dye characterized by its orange emission (λex=554, λem=568). This dye is widely utilized for labeling proteins and nucleic acids in various biological assays. Its strong fluorescent properties make it an ideal choice for applications in fluorescence microscopy, flow cytometry, and in situ hybridization. CY3 facilitates the visualization and analysis of molecular interactions within complex biological systems. -
Fluorescent Dye
Cy5.5 is a cyanine fluorescent dye known for its long-wavelength absorption and emission properties. It features a high extinction coefficient and good water solubility, making it suitable for a variety of biological applications. Cy5.5 is commonly utilized for the labeling of proteins, antibodies, and small molecules, facilitating applications such as fluorescence microscopy, flow cytometry, and in vivo imaging. The straightforward labeling process through simple mixing reactions enhances its utility in various research settings. -
Reactive Dye
CY5 is a reactive dye that belongs to the Cyanine family, characterized by its long wavelength absorption and emission properties. Its high extinction coefficient and excellent water solubility make it ideal for bioconjugation applications. Commonly utilized for labeling proteins, antibodies, and small molecular compounds, CY5 enables efficient visualization and tracking in various biological assays. The labeling process can be performed through a straightforward mixing reaction, facilitating its use in diverse research settings. -
Reactive Dye
CY5-SE (Cy5 NHS Ester) is a reactive dye specifically designed for the labeling of amino groups in peptides, proteins, and oligonucleotides. This reagent facilitates efficient labeling reactions in the presence of minimal organic co-solvents, such as DMF or DMSO. CY5-SE is particularly suitable for cost-effective labeling of soluble proteins, peptides, and oligonucleotides, as well as for labeling small molecules in organic solvents. With an excitation wavelength of 649 nm and an emission wavelength of 670 nm, this dye is valuable for a range of fluorescence-based assays and applications in biochemical research. -
Fluorescent Dye
HaloTag TMR is a red fluorescent dye designed for the specific labeling of HaloTag proteins. This compound consists of HaloTag ligand molecules conjugated with TMR (TAMRA), allowing for rapid and stable covalent binding with high specificity and affinity. With excitation and emission wavelengths of 550 nm and 576 nm, respectively, it is ideal for a range of biological applications, including live-cell imaging and protein localization studies. -
Fluorescent Probe
PS-SCOTfluor-12 is a fluorescent probe designed for the imaging of lactic acid metabolism in living cells. With an excitation wavelength of 485 nm and an emission wavelength of 605 nm, it allows for the visualization of metabolic processes in real-time. This reagent is particularly valuable for studies in cancer research and other fields where lactic acid metabolism plays a critical role. -
Peroxynitrite Fluorescent Probe
DMANI is a peroxynitrite fluorescent probe that employs an intramolecular charge transfer (ICT) mechanism for ratiometric detection. This probe selectively targets mitochondria, enabling the monitoring of mitochondrial peroxynitrite (ONOO−) levels in living cells. DMANI serves as a valuable tool for studying oxidative stress and related pathophysiological processes in cellular environments. -
DKK1 Inhibitor
Gallocyanine chloride is a DKK1 inhibitor that targets the DKK1/LRP6 interaction, exhibiting an IC50 of 6.38 μM. This compound is relevant for research into Alzheimer's disease and related neurodegenerative tauopathies, as it activates the Wnt signaling pathway and promotes β-catenin accumulation. Additionally, Gallocyanine chloride demonstrates anti-metastatic, anti-inflammatory, and anti-fibrotic properties, and can serve as a fluorescent probe for the detection of superoxide anion radicals. -
PH Indicator
Pyranine is a cell-impermeant, pH-sensitive fluorescent indicator that serves primarily as a pH monitor. This compound exhibits strong fluorescence and acts as a chemosensor for copper ions (Cu+), making it valuable for various biochemical applications. Pyranine is widely utilized as a biological stain, optical detecting reagent, and as a coloring agent in research environments, with an excitation/emission spectrum of 450/510 nm. Its ability to provide precise pH measurements enhances its utility in various experimental setups. -
Calcium Ion Indicator
Mag-Fluo-4 AM is a fluorescent calcium ion indicator that exhibits a high affinity for Ca²⁺. This compound enables the specific detection of intracellular calcium ions with exceptional sensitivity and minimal cytotoxicity. Upon entering the cell, it is hydrolyzed by intracellular esterases, allowing it to bind calcium ions and emit strong fluorescence. Mag-Fluo-4 AM is widely applicable in studies involving calcium signaling and cellular functions. -
Iron Dye Reagent
Ferrozine is an iron dye reagent that specifically targets divalent iron ions (Fe2+). Upon reaction, it forms a stable magenta complex, which exhibits a maximum absorption peak at 562 nm. This property enables the use of Ferrozine in colorimetric assays for the quantitation of iron in biological samples, facilitating research in iron metabolism and cellular iron homeostasis. -
Biochemical Assay Reagent
Bathocuproine disulfonate disodium (BCS) is a highly sensitive colorimetric reagent utilized for the detection of copper ions in biochemical assays. This compound exhibits a bright yellow color and possesses strong absorbance at specific wavelengths, enabling the quantification of trace levels of copper. BCS is instrumental in studying copper's biological roles, as well as in environmental monitoring and water quality testing, where its sensitivity allows for the identification of copper pollution, even at minimal concentrations. Accurate measurement of copper is essential for understanding its physiological effects and ecological impacts. -
Reference Dye
Diphenyl Blue, also known as Trypan Blue, is a vital reference dye primarily used to assess cell membrane integrity and viability. It selectively stains dead or damaged cells blue, allowing for the identification of non-viable cells in various tissue and cell culture applications. Viable cells with intact membranes exclude the dye, while macrophages can phagocytize Diphenyl Blue, making it an effective living stain for studying these immune cells. This dye is essential for research involving cell viability assays and tissue analyses. -
ROS Probe
Lucigenin is a chemiluminescence probe primarily utilized for the detection of the endogenous superoxide anion radical (O2-). This compound exhibits high sensitivity and can also function as a chloride indicator, as its fluorescence is quenched in the presence of chloride ions. With excitation and emission wavelengths of 455 nm and 505 nm, respectively, Lucigenin serves as a valuable tool in studies involving reactive oxygen species and chloride ion interactions. -
Lipophilic Fluorescent Dye
BODIPY 505/515 is a lipophilic fluorescent dye with a strong ultraviolet absorption capacity and sharp fluorescence peak, offering a high quantum yield. This compound exhibits stability across various physiological conditions and is relatively insensitive to environmental polarity and pH. BODIPY 505/515 effectively penetrates cell membranes, allowing specific labeling of neutral lipids within lipid droplets in both live and fixed cells. It is ideal for applications in cellular imaging, studying lipid metabolism, and analyzing cellular lipid storage. Maximum excitation and emission wavelengths are 505 nm and 515 nm, respectively. -
Fluorescent Probe
2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe utilized for the detection of reactive oxygen species (ROS). It becomes fluorescent upon cleavage by intracellular esterases and subsequent oxidation, allowing for the assessment of oxidative stress levels in biological systems. This reagent is essential for studies in toxicology and cellular signaling, enabling researchers to monitor and evaluate oxidative phenomena in various experimental contexts. -
Cu+ Probe
Copper Fluor-4 (CF4) is a highly selective fluorescent probe for Cu+ ions, utilizing a rhodol dye scaffold. With a Kd value of 2.9×10−13 M, it demonstrates exceptional selectivity for copper over competing metal ions such as zinc and iron, as well as common cellular alkali and alkaline earth metals. Copper Fluor-4 remains stable within a physiologically relevant pH range of 6 to 8, making it suitable for various biological applications, including imaging and quantification of copper ions in live cells. Excitation occurs at 415 nm with emission at 660 nm. -
pH Indicator Dye
Phenol Red is a pH indicator dye that exhibits a notable color transition from pink to yellow in response to changes in acidity. This property makes it essential for applications in cell culture and biological research, where monitoring pH levels is crucial for maintaining optimal conditions for cell viability and function. Phenol Red is widely utilized in laboratory assays and as a diagnostic tool for evaluating the conditions of various biological systems. -
Fluorescent Probe
MitoPerOx is a fluorescent probe designed to detect lipid peroxidation specifically in mitochondria, utilizing BODIPY581/591 fluorophores. With its triphenylphosphine cation (TPP+), MitoPerOx selectively accumulates in mitochondria based on membrane potential, allowing for sensitive measurement of lipid peroxides within the inner mitochondrial membrane. The probe exhibits a ratiometric emission shift from 590 nm to 520 nm upon oxidation, facilitating accurate detection at an excitation wavelength of 488 nm. MitoPerOx is valuable for investigating oxidative stress-associated diseases, including aging, neurodegenerative disorders, and mitochondrial dysfunction. -
Fluorescent Dye
Lucifer Yellow CH dipotassium salt functions as a high-intensity fluorescent dye, primarily utilized for its ability to react with fatty aldehydes at room temperature. This probe is valuable in biological research for tracing neuronal branching, monitoring regeneration, and detecting gap junctions, as well as for selective ablation of cells following aldehyde fixation. It exhibits optimal excitation and emission wavelengths of 430 nm and 540 nm, respectively, making it an effective tool in various fluorescence microscopy applications. -
Fluorescent Probe
Carboxy-SNARF 1 (5/6-mixture) is a pH-sensitive fluorescent probe utilized for the measurement of intracellular and environmental pH changes. It exhibits a significant emission shift from yellow-orange (Em: 580 nm) at acidic pH to deep red fluorescence (Em: 640 nm) in basic conditions, making it particularly useful for dynamic pH monitoring in biological systems. This probe is valuable in various research applications, including studying cellular metabolism, enzyme activity, and membrane potential. -
Lymphocyte Tracker
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell-permeable fluorescent dye with an excitation wavelength of 492 nm and an emission wavelength of 517 nm. It covalently labels intracellular proteins, enabling the tracking of lymphocyte migration and proliferation in biological research. This reagent is particularly useful for studying immune responses and cellular dynamics in various experimental settings. -
Chemical
1,8-Diazafluoren-9-one is a chemical reagent primarily utilized in forensic analysis for the detection of latent fingerprints on porous surfaces. This compound reacts with amino acids found in fingerprints, resulting in the formation of highly fluorescent derivatives, with an excitation/emission maximum of approximately 470/570 nm. Its applications extend to enhancing imaging techniques in forensic science, facilitating reliable identification in criminal investigations. -
Calcium Indicator
Fluo-3 AM is a fluorescent calcium indicator that effectively chelates Ca2+ ions with high affinity. It is designed for the sensitive detection of intracellular calcium fluctuations, making it a valuable tool for monitoring cellular calcium dynamics. Due to its low cytotoxicity and efficient cellular uptake facilitated by the acetoxymethyl ester moiety, Fluo-3 AM is cleaved intracellularly, allowing for sustained binding to calcium ions and robust fluorescence output. This compound is widely used in studies related to signal transduction, muscle contraction, and various calcium-dependent cellular processes. -
Fat-soluble Diazo Dye
Sudan Black B is a fat-soluble diazo dye used primarily as a histochemical stain. This reagent effectively stains neutral triglycerides and lipids, making it a valuable tool in the identification and analysis of adipose tissues and lipid-containing structures in biological samples. Its applications extend to research in lipid metabolism, pathology, and histological studies. -
Cell Proliferation Assay Reagent
WST-1 is a water-soluble tetrazolium salt that serves as a reagent for cell proliferation assays. It selectively undergoes reduction by intracellular mitochondrial dehydrogenases, resulting in the production of a soluble formazan product detectable at 450 nm. This compound is utilized to assess cell viability and cytotoxicity, making it an essential tool in various biological and pharmacological research applications. -
Golgi-specific Fluorescent Dye
BODIPY FL C5-Ceramide is a Golgi-specific fluorescent dye that targets the Golgi apparatus for precise cellular visualization. This BODIPY-labeled ceramide derivative is synthesized in the endoplasmic reticulum and is effectively transported to the Golgi through ceramide transport proteins or vesicular mechanisms. With an excitation/emission wavelength of 505 nm/512 nm, it is suited for applications in cell biology and imaging studies, allowing researchers to observe and analyze cellular structures with enhanced clarity. -
Supravital Stain
Janus Green B is a supravital stain utilized for the visualization of live cells and tissues. This compound exhibits an oxygen-dependent staining reaction that can be reversibly inhibited by cyanide, making it a valuable tool in live-cell imaging. It has been effectively employed in the staining of peripheral nerves in insects, lymphatic vessels in rabbits, and mitochondria, aiding in various biological research applications related to cellular morphology and function. -
Fluorescent Dye
4-Di-1-ASP is a styryl dye that targets glioma cells for fluorescent imaging in live brain tissue. This reagent enables detailed analysis of cellular structures, viability, proliferation, and endocytic processes, including cytokinesis and phagocytosis. Additionally, 4-Di-1-ASP facilitates observations of mitochondrial architecture in living cells, exhibiting green fluorescence upon excitation (λex /λem = 475/606 nm). -
Fluorescent Probe
BODIPY-C12 is a boron-dipyrromethene derivative functioning as a fluorescent probe with an excitation wavelength of 490 nm. Its hydrophobic structure allows it to be highly sensitive to its surrounding environment, making it suitable for quantifying viscosity, critical micelle concentration, and critical micelle temperature. This compound serves as a valuable tool for researchers in assessing lipid environment dynamics and micelle formation in various biological studies. -
Fluorescent Dye
Calcein (mixture of isomers) is a calcium-dependent fluorescent dye that enables the visualization of calcium ions in biological systems. This reagent is commonly utilized in studies of bone metabolism and is effective for staining specific cellular regions in vitro. Additionally, Calcein can be employed in fluorometric assays and for the titration of calcium ions using EDTA, making it a versatile tool for various research applications. -
Fluorescent Dye
3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine fluorescent dye primarily used for the assessment of mitochondrial membrane potential. This dye exhibits significant fluorescence characteristics, making it an effective tool for studying mitochondrial dynamics and function in various cellular processes. It is widely utilized in research applications involving cell viability, apoptosis studies, and mitochondrial health assessments. -
pH Sensitive Fuorescent Probe
9-Amino-6-chloro-2-methoxyacridine is a pH-sensitive fluorescent probe that exhibits significant changes in fluorescence intensity in response to pH variations. This compound is particularly useful for monitoring vacuolar pH changes during substrate transport across the tonoplast via a proposed H+/solute antiport mechanism. Its application in cellular and molecular research facilitates the understanding of acid-base homeostasis in plant cells and other biological systems. -
Tumor Targeted Dye
MHI-148 is a near-infrared heptamethine cyanine dye that selectively targets tumors, making it ideal for cancer detection and diagnosis. This compound demonstrates preferential accumulation in the lysosomes and mitochondria of tumor cells, allowing for enhanced visualization. Its unique properties facilitate research applications in tumor biology and imaging studies, enabling more effective monitoring and understanding of cancer progression. -
Fluorescent Dye
2,3-Diaminonaphthalene is a selective fluorescent dye primarily used for the detection of selenium ions. It exhibits strong colorimetric and fluorometric properties, making it suitable for quantifying nitrite levels as well. This reagent finds applications in environmental monitoring and analytical chemistry, enabling sensitive detection and measurement of specific analytes in various research settings. -
Lipid Fluorescent Probe
NBD-PE is a lipid fluorescent probe that targets lipid bilayers, excelling in membrane and cell biology research. With an excitation wavelength of 465 nm and emission at 535 nm, this compound facilitates visualization of cellular membranes and lipid dynamics. Key applications include studying membrane structure, dynamics, and interactions in live cell imaging. -
Fluorescent Dye
BODIPY 500/510 C1, C12 is a fluorescent dye characterized by strong ultraviolet absorption and high quantum yield. It features a sharp fluorescence peak and remains stable across various physiological conditions, demonstrating minimal sensitivity to polarity and pH variations. This dye effectively penetrates cell membranes, allowing for the specific localization of neutral lipids within lipid droplets in both live and fixed cells. It is widely utilized for cellular imaging and lipid droplet labeling applications. Maximum excitation and emission wavelengths are 500 nm and 510 nm, respectively. Protect from light and store at -20°C.
