Catalog No.
Product Name
Application
Product Information
Citations
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Mg2+ Fluorescent Probe
KMG-301AM TFA is an acetoxymethyl ester derivative of KMG-301, designed as a fluorescent probe targeting Mg2+ within mitochondria. Once inside the mitochondria, it is hydrolyzed to KMG-301, which selectively measures Mg2+ concentrations in live cells, as it remains confined within the mitochondria due to the impermeability of the mitochondrial membrane. This probe is suitable for assessing Mg2+ transport and monitoring changes in mitochondrial Mg2+ levels, providing valuable insights in cellular models of mitochondrial function and dysfunction. -
Fluorescent Dye
BHQ-1 NHS is a fluorescent dye designed for efficient labeling of nucleotide sequences. This compound serves as a quencher, offering enhanced fluorescence signaling for applications in nucleic acid research and diagnostics. BHQ-1 NHS is particularly valuable in the development of real-time PCR assays and other molecular biology techniques requiring precise fluorescence modulation. -
Fluorescent Dye
H-FluNox is a selective fluorescent probe designed to detect labile heme through biomimetic N-oxide deoxygenation, which activates its fluorescence. This compound demonstrates over 100-fold selectivity for labile heme compared to Fe(II), facilitating the differentiation of labile heme from intracellular Fe(II) pools. H-FluNox's high sensitivity enables the detection of labile heme at the subcellular level, making it an invaluable tool for studies of heme dynamics and related biological processes. -
Fluorescent Dye
MitoMark Red I is a fluorescent dye specifically designed to target mitochondria in viable cells. This red fluorescent marker exhibits a peak excitation wavelength of 578 nm and an emission at 599 nm, enabling precise visualization of mitochondrial activity and dynamics. It is widely utilized in cellular and molecular biology research to study mitochondrial function, cell viability, and related physiological processes. -
HOCl Fluorescent Probe
EtS-DMAB is a fluorescent probe designed for the selective detection of hypochlorous acid (HOCl). Exhibiting fluorescence with excitation at 440 nm and emission at 610 nm, it is used to visualize both exogenous and endogenous levels of HOCl in live cells. This compound is valuable for studies involving oxidative stress and inflammation, providing insights into cellular responses under specific pathological conditions. -
Fluorescent Dye
DHPDS disodium salt is a pH-sensitive fluorescent dye that enables the measurement of intracellular pH (pHi). This compound is particularly useful in experimental setups involving isolated perfused rat liver, where it facilitates the assessment of pH variations through surface fluorescence. Its application extends to various biological studies requiring precise pH measurements in living cells. -
Fluorescent Substrate
Z-VEID-AFC is a fluorescent substrate specifically designed for the detection of caspase-6 activity. Upon cleavage by active caspase-6, it releases a fluorescent signal, making it useful for monitoring apoptotic processes in various biological systems. This reagent serves as a valuable tool in studies related to cell death, neurodegeneration, and tumor biology, facilitating the investigation of caspase-related pathways in research applications. -
Fluorescent Dye
R-Phycoerythrin (R-PE) is an orange-red fluorescent dye derived from the red algae Heterosiphonia japonica. This fluorescent probe consists of α, β, and γ subunits and is widely utilized in fluorescence microscopy, flow cytometry, and immunofluorescence analysis, with an excitation wavelength of 495 nm. Additionally, R-PE is employed in photodynamic therapy (PDT) for inducing apoptosis in tumor cells, making it a valuable tool in cancer research and diagnostics. -
Bacterial Growth Probing
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue-emitting (λem ≈ 450 nm) fluorescent D-amino acid (FDAA) used for labeling bacterial cell walls. FDAAs are incorporated into peptidoglycan (PG) at sites of active biosynthesis through the action of native transpeptidases, enabling specific and covalent labeling of growing bacterial cells with minimal disruption to normal physiology. HADA hydrochloride provides high spatial and temporal resolution for visualizing bacterial growth dynamics, cell wall synthesis, and morphogenesis in live-cell imaging studies, making it a powerful tool in microbiology and antibiotic mechanism research. -
Chemiluminescent Probe
L-012 sodium salt is a luminol-based chemiluminescent probe widely used for the sensitive detection of reactive oxygen and nitrogen species (ROS and RNS) in biological systems. It is particularly effective in monitoring NADPH oxidase (Nox)-derived superoxide production, providing high signal intensity and low background interference. Compared with conventional luminol, L-012 offers enhanced chemiluminescence sensitivity and stability, enabling real-time detection of oxidative and nitrosative stress in cells, tissues, and *in vivo* models. It is a valuable tool for studying redox signaling, inflammation, and oxidative stress–related pathophysiology. -
Lipid Droplets Probe
BODIPY 558/568 C12 is a fluorescent lipid probe based on the BODIPY (boron-dipyrromethene) dye structure. BODIPY dyes are small-molecule fluorophores characterized by strong ultraviolet-visible absorption, sharp fluorescence emission peaks, high quantum yields, and remarkable photostability. They are largely insensitive to environmental polarity and pH, maintaining consistent fluorescence under various physiological conditions. BODIPY 558/568 C12, due to its lipophilic alkyl chain, readily permeates cell membranes and specifically localizes to neutral lipid compartments, enabling selective staining of lipid droplets in both live and fixed cells. It serves as a reliable fluorescent marker for studying lipid metabolism, lipid droplet dynamics, and cellular lipid distribution. The dye exhibits maximum excitation and emission wavelengths at 558 nm and 568 nm, respectively. -
Biochemical Assay Reagent
Rhodamine B isothiocyanate (RBITC) is a reactive fluorescent dye widely used for covalent labeling of biomolecules in imaging and analytical applications. The isothiocyanate functional group readily reacts with primary amines on proteins, peptides, and other biomolecules to form stable thiourea linkages, enabling durable fluorescent tagging. RBITC emits bright orange-red fluorescence upon green light excitation, providing strong signal intensity and excellent photostability for visualization in complex biological systems. Owing to its high sensitivity, chemical stability, and compatibility with diverse assay conditions, RBITC is extensively utilized in cell biology, immunology, neurobiology, and fluorescence microscopy studies for tracking molecular localization and dynamics. -
Fluorochrome
WSP-5 is a selective fluorescent probe designed for rapid detection of hydrogen sulfide (H₂S) in biological samples and live cells. It operates via a reaction-based “fluorescence turn-on” mechanism, in which WSP-5 reacts specifically and swiftly with H₂S to generate a highly fluorescent product. The probe exhibits excitation and emission maxima at 502 nm and 525 nm, respectively. Due to its excellent selectivity, sensitivity, and biocompatibility, WSP-5 is widely used in studies of H₂S biology, cellular signaling, and redox homeostasis. -
Amino Acid Sequence Detection Reagent
AQC (6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate) is a highly sensitive derivatization reagent used for amino acid and peptide analysis by high-performance liquid chromatography (HPLC) with fluorescence detection. It reacts rapidly with both primary and secondary amino groups to form stable fluorescent derivatives, enabling detection of amino acids at sub-picomolar concentrations. Due to its high reactivity, stability, and strong fluorescence yield, AQC is widely applied in protein sequencing, amino acid quantification, and metabolic profiling, providing exceptional sensitivity and reproducibility in analytical and biochemical studies. -
Fluorescent Dye
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a thiol-reactive fluorescent dye widely used for covalent labeling of proteins, peptides, and other biomolecules containing cysteine residues. By forming stable thioether bonds with sulfhydryl groups, it enables precise detection and quantification of thiol-containing targets. Fluorescein-5-maleimide is employed to monitor the redox state of thiols in eukaryotic cells, label peptides or actin for protein–protein interaction studies—such as investigations of actin binding to cardiac myosin-binding protein C (cMyBP-C)—and to detect negatively charged nanoparticles. It also serves as a tool for screening mutant proteins containing cysteine residues. The dye exhibits strong fluorescence with excitation and emission maxima at 494 nm and 519 nm, respectively, making it highly suitable for fluorescence microscopy, flow cytometry, and biochemical assays. -
Azo Dye
Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active synthetic azo dye that appears as an orange-yellow, water-soluble powder producing a bright yellow coloration in solution. It is widely used as a food colorant and in pharmaceuticals and cosmetics due to its high chemical and photostability. Beyond its industrial applications, Tartrazine has been reported to induce mitochondria-mediated apoptosis and to exhibit potential biological effects, including neurodevelopmental toxicity, cytotoxicity, and genotoxicity under certain experimental conditions. It serves as a model compound in toxicological and biochemical studies investigating the safety and cellular impact of synthetic food dyes. - Dansyl chloride is a fluorescent labeling reagent that reacts with primary and secondary amines to form stable blue or blue-green fluorescent sulfonamide adducts. It readily labels aliphatic and aromatic amines through reaction with amino groups, making it a valuable tool for biochemical analysis. Dansyl chloride is widely used for amino acid derivatization, protein sequencing, and amino acid composition analysis, enabling sensitive fluorescence-based detection and quantification of amine-containing biomolecules.
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Fluorescent Tag
Ethidium bromide is a fluorescent intercalating agent widely used in molecular biology as a nucleic acid stain. It inserts between DNA base pairs, allowing visualization of DNA and RNA under ultraviolet (UV) light during techniques such as agarose gel electrophoresis. Due to its high sensitivity and strong fluorescence, Ethidium bromide is a standard tool for nucleic acid detection, though it is handled with caution because of its mutagenic properties. -
Fluorescent Dye
DiI is a long-chain lipophilic carbocyanine dye commonly used for fluorescent labeling of biological membranes. Due to its strong affinity for lipid bilayers, DiI efficiently integrates into cell membranes, making it ideal for tracing cells, organelles, liposomes, viruses, and lipoproteins. It exhibits bright fluorescence, high photostability, and minimal cytotoxicity, enabling long-term imaging and tracking in both fixed and live-cell applications. -
fluorescent probe
Coumarin 6 is a fluorescent dye commonly used as a probe in drug delivery research. It serves as a tracer in microparticle and nanoparticle delivery systems, enabling *in vivo* tracking, cellular uptake analysis, and transport mechanism studies. Coumarin 6 exhibits strong fluorescence with excitation and emission maxima at λexc = 450 nm and λem = 505 nm, respectively, making it an ideal marker for evaluating drug distribution and release profiles in biological systems. -
Fluorescent dye
PKH26 is a red fluorescent dye that stably incorporates into the lipid regions of the cell membrane, emitting red fluorescence (Ex/Em: 551/567 nm). It is commonly used for in vitro cell labeling, cell proliferation assays, and both in vivo and in vitro cell tracking studies. -
Fluorescent Dye
BODIPY 581/591 C11 is a boron-dipyrromethene (BODIPY) derivative with excellent photostability and minimal fluorescence artifacts. It is widely used to study lipid peroxidation and antioxidant activity in living cells, and to detect ferroptosis through its reaction with hydroxyl radicals. The dye exhibits a fluorescence shift upon oxidation: the reduced form emits at 591 nm (Ex: 581 nm), while the oxidized form emits at 510 nm (Ex: 500 nm). -
Mitochondrial Membrane Potential Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by sensing mitochondrial membrane potential, resulting in bright fluorescence. Due to their low cytotoxicity at appropriate concentrations, they are widely used for mitochondrial labeling in animal cells, plant cells, and microorganisms. -
Fluorescent Probe
DiO is a long-chain carbocyanine dye commonly used for labeling cells, organelles, liposomes, viruses, and lipoproteins. As a member of the Di-series carbocyanine dyes, DiO integrates into lipid membranes, enabling effective fluorescent tracking in various biological systems. -
fluorescent probe
RhoNox-1 is a fluorescent probe designed for the specific detection of divalent iron ions (Fe²⁺). Upon reaction with Fe²⁺, RhoNox-1 forms an irreversible orange-red fluorescent product (Ex/Em: 540/575 nm). It efficiently penetrates cell membranes and is suitable for detecting intracellular Fe²⁺, with a tendency to localize in the Golgi apparatus. - Calcein AM is a cell-permeable, non-fluorescent dye that readily enters live cells. Once inside, it is hydrolyzed by intracellular esterases to generate Calcein, a polar and highly negatively charged molecule that is retained within the cytoplasm. Calcein emits strong green fluorescence (Ex/Em: 494/515 nm) and is commonly used in combination with Propidium Iodide for assessing cell viability and cytotoxicity.
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Fluorescent Probe
Laurdan is a membrane-permeable fluorescent probe that exhibits spectral sensitivity to the phospholipid phase of the membrane it integrates into. Measurement of its generalized polarization (GP) enables quantification and distinction of membrane phases, such as liquid-ordered and liquid-disordered states. -
Mitochondrial Membrane Potential Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by recognizing mitochondrial membrane potential, producing bright fluorescence. At appropriate concentrations, they exhibit low cytotoxicity and are widely used for mitochondrial staining in animal cells, plant cells, and microorganisms. -
Fluorescent Dye
BODIPY-cholesterol is a lipophilic, cell-permeable fluorescent analog of cholesterol, labeled with a BODIPY fluorophore (Ex/Em: 505/515 nm). It is commonly used to monitor sterol uptake, distribution, and inter-organelle trafficking in live cells. -
Fluorescent Dye
Coppersensor-1 (CS1) is a membrane-permeable fluorescent probe with picomolar affinity for Cu⁺ ions, exhibiting high selectivity over other cellular metal ions. It enables sensitive and selective detection of copper(I) in biological samples, including live cells. CS1 is suitable for imaging studies related to copper homeostasis in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. -
Red Fluorescent Dye
FM4-64 is a highly lipophilic, water-soluble styryl dye that selectively binds to the plasma membrane and internal membrane-bound organelles, producing bright fluorescence. It is widely used as a marker for endocytic and exocytic membrane structures in live-cell imaging studies. -
Fluorescent Dye
CellTracker Blue CMAC is a non-fluorescent, cell-permeable dye that becomes fluorescent upon enzymatic conversion by intracellular glutathione (GSH). The chloromethyl groups are cleaved to yield a blue fluorescent product (Ex/Em: 360/460 nm). It is suitable for long-term cell tracking (up to 72 hours), cell proliferation studies, and quantification of intracellular GSH levels. -
Fluorescent Probe
DiSC3(5) is a fluorescent probe commonly used to assess mitochondrial membrane potential, with excitation/emission maxima at 622/670 nm. It can inhibit mitochondrial NAD-linked respiratory activity, with an IC₅₀ of 8 μM. In the presence of the Na⁺/K⁺-ATPase inhibitor ouabain, DiSC3(5) induces membrane hyperpolarization in Ehrlich ascites tumor cells. -
Red Fluorescent Dye
MitoTracker Deep Red FM is a fluorescent dye that selectively accumulates in the mitochondrial matrix and covalently binds to mitochondrial proteins by reacting with free thiol groups of cysteine residues. This allows for stable mitochondrial labeling independent of membrane potential. The dye has excitation/emission maxima at 644/665 nm. Store protected from light. -
Cell Death Indicator
LysoTracker Red is a red-fluorescent lysosomal probe with excitation/emission maxima at 577/590 nm. It consists of a fluorophore linked to a weakly basic moiety, allowing it to freely cross cell membranes and selectively accumulate in acidic organelles such as lysosomes. LysoTracker Red is commonly used for visualizing lysosomal structures and studying lysosome-related biosynthesis and pathogenesis. -
Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by recognizing mitochondrial membrane potential. They generate bright fluorescence upon localization and exhibit low cytotoxicity at appropriate concentrations. Rhodamine dyes are widely used for mitochondrial staining in animal cells, plant cells, and microorganisms. -
Fluorochrome
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe developed for the selective detection and quantification of hydrogen peroxide in the presence of various reactive nitrogen and oxygen species (RNOS). For nearly two decades, DPBF has been widely used as a specific indicator for reactive oxygen species, particularly singlet oxygen, hydroxyl radicals, alkoxyl radicals, and alkylperoxy radicals. -
RNA Aptamers Probe
DFHBI-1T is a membrane-permeable fluorescent probe activated by RNA aptamers, with excitation/emission maxima at 472/507 nm. It specifically binds to aptamers such as Spinach, Spinach2, iSpinach, and Broccoli, resulting in bright fluorescence with low background signal. DFHBI-1T is commonly used for live-cell imaging of RNA. -
DNA Fluorescent Stain
Hoechst 33342 trihydrochloride is a cell-permeable fluorescent dye from the Hoechst series, widely used as a live-cell nuclear marker. It binds preferentially to the minor groove of A/T-rich regions in double-stranded DNA, resulting in enhanced fluorescence intensity. Although it can associate with various nucleic acids, its fluorescence is significantly stronger upon binding to A/T-rich DNA. Hoechst 33342 is suitable for labeling live cells, and its fluorescence intensity increases with rising solution pH. -
Fluorescent dye
Rhodamine B is a fluorescent dye widely used for staining applications. It is commonly employed in the dyeing of textiles, paper, soap, leather, and various industrial agents. -
Endoplasmic Reticulum Fluorescent Dye
ER-Tracker dye is a BODIPY-based fluorescent probe conjugated with Glibenclamide, exhibiting high selectivity for the endoplasmic reticulum (ER). It is cell-permeable, non-toxic at low concentrations, and retains partial fluorescence after formaldehyde fixation. As an environment-sensitive dye, R-Tracker offers a long fluorescence lifetime and a high extinction coefficient. Glibenclamide, an ATP-sensitive K⁺ channel (Kir6.x, KATP) and CFTR Cl⁻ channel blocker, mediates ER targeting. R-Tracker is not suitable for post-fixation staining. -
Membrane Dye
DiR is a long-chain carbocyanine dye commonly used for labeling and tracking biological structures. As a member of the Di series of dyes, DiR is particularly suited for labeling cells, organelles, liposomes, viruses, and lipoproteins due to its strong membrane affinity and near-infrared fluorescence properties. -
Fluorescent Dye
IR780 is a prototypic near-infrared (NIR) heptamethine cyanine dye with a high molar extinction coefficient. It exhibits a maximum excitation wavelength of 777–780 nm and a maximum emission wavelength of 798–823 nm. IR780 is widely used in cancer research for photothermal therapy (PTT), photodynamic therapy (PDT), and imaging applications. -
Luciferin analogue
AkaLumine hydrochloride is a luciferin analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. It is commonly used in bioluminescence imaging and reporter assays for enhanced sensitivity and signal stability. -
Mitochondrial Dye
MitoTracker Green FM is a green fluorescent dye that selectively targets the mitochondrial matrix. It covalently binds to mitochondrial proteins through reaction with free mercaptan groups on cysteine residues, facilitating the visualization of mitochondrial structures independently of membrane potential. This dye is widely utilized in cellular and molecular biology research to study mitochondrial dynamics, function, and viability. Excitation and emission wavelengths are 490 nm and 523 nm, respectively. -
Green Fluorescent Dye
PKH 67 is a green fluorescent dye primarily used for staining cell membranes. With an excitation/emission range of 490/502 nm, it enables precise labeling of cells to facilitate studies of cell proliferation in vitro and tracking of cells in both in vitro and in vivo environments. This dye is commonly employed alongside the non-specific red fluorescent dye PKH26 to enhance multi-color cell analysis. -
Cellular Zinc Fluorescent Sensor
TSQ is a membrane-permeable fluorescent probe designed for the detection of zinc ions within cells, specifically targeting the cytosolic compartment. It exhibits a fluorescence emission maximum at approximately 495 nm when excited at 334 nm, enabling effective intracellular imaging of zinc-containing proteins. TSQ forms a complex with Zn2+ in the presence of Ca2+ and Mg2+, resulting in a distinctive blue fluorescence signal, making it a valuable tool for research applications involving cellular zinc dynamics and metalloprotein studies. -
Diazol Dye
Oil Red O is a fat-soluble diazol dye that primarily targets neutral lipids and cholesteryl esters, exhibiting maximum absorption at 518 nm. This reagent is widely utilized for the detection and quantification of hepatic steatosis in mouse liver biopsies, allowing for the visualization of significant metabolic changes in tissues. Oil Red O staining serves as an essential tool for researchers studying metabolic diseases and their progression. -
Fluorescent Dye
Thiazole Orange is a fluorescent dye primarily designed for nucleic acid detection. It exhibits significant fluorescence enhancement upon binding to DNA and RNA, making it ideal for applications such as biomolecular detection, gel staining, and reticulocyte analysis. This dye permeates living cell membranes and can be detected using ultraviolet or blue light, with an excitation maximum at 510 nm (also excitable at 488 nm and 470 nm) and an emission maximum at 527 nm. -
Fluorescent Probe
Acridine Orange 10-Nonyl Bromide is a fluorescent probe primarily targeting cardiolipin. This compound exhibits excitation maximum at 489 nm and emission maximum at 525 nm, making it suitable for studies involving mitochondrial function and apoptosis. It is widely used in various biological research applications, particularly in understanding membrane dynamics and cellular lipid interactions.
