Catalog No.
Product Name
Application
Product Information
Citations
-
Fluorescent pH Indicator
OG 488, SE (Oregon Green 488 succinimidyl ester) is a fluorescent pH indicator that exhibits strong fluorescence properties. It is widely utilized in biochemistry and neurosciences for various applications, including cellular imaging and tracking pH changes in live cells. Its ability to provide real-time pH measurements makes it an invaluable tool for researchers studying cellular processes and physiological conditions. -
Fluorogenic Probe
HKYellow-AM (6/12-mixture) is a fluorogenic probe designed for the selective and sensitive detection of peroxynitrite (ONOO-) in living cells and tissues. This probe offers a non-cytotoxic option for real-time fluorescence imaging, enabling researchers to investigate oxidative stress and related pathophysiological processes. Its high selectivity allows for accurate assessment of ONOO- levels, making it a valuable tool for studies in cellular signaling and antioxidant defense mechanisms. -
Fluorescent Probe
5-CFDA-AM is a fluorescent probe designed to measure enzyme activity and assess cell membrane integrity. This cell-permeable esterase substrate enters cells efficiently and is hydrolyzed by intracellular esterases to form carboxyfluorescein, which exhibits enhanced retention due to its negative charge. Its quantitative fluorescence capacity makes it a valuable tool for various biological research applications, including studies on cellular processes and viability assessments. -
Histochemical Stain
X-34 is a lipophilic fluorescent derivative of Congo red, characterized by its bright yellow-green fluorescence. It selectively stains neuritic and diffuse plaques, neurofibrillary tangles, neuropil threads, and cerebrovascular amyloid in brain tissue. This reagent is widely utilized in research focused on Alzheimer's disease to facilitate the study of these key pathological features. -
Fluorophore
6-HEX is a fluorophore characterized by its excitation and emission wavelengths of 532 nm and 556 nm, respectively. It is particularly effective for recording nucleic acid sequences and is useful in the design of optical materials. Additionally, 6-HEX can be employed to visualize nucleic acids under 543 nm radiation, as well as to directly locate cell group bases using 550 nm and 650 nm wavelengths. -
Fluorescent Dye
ANTS is a fluorescent dye characterized by an excitation wavelength of 380 nm and an emission wavelength of 520 nm. This compound is utilized for assessing membrane integrity, particularly in studies involving liposomal formulations, where it effectively measures membrane leakage when encapsulated alongside DPX. ANTS is a valuable tool in biochemical and cellular research applications that require precise monitoring of membrane dynamics. -
Fluorescent Dye
Phenazine ethosulfate is a cationic fluorescent dye characterized by an excitation wavelength of 390 nm and an emission wavelength of 530 nm. This compound serves as an electron acceptor and is utilized in dye-linked enzyme assays. It is particularly effective in detecting nitric oxide reductase (Nors) activity in conjunction with ascorbic acid, making it valuable for biochemical research involving enzyme functions and redox reactions. -
Fluorescent Dye
6-NBDG is a fluorescent glucose analogue that selectively targets glucose transport mechanisms. It serves as an effective tool for fluorescence imaging, enabling the monitoring of glucose uptake in various biological contexts. Additionally, 6-NBDG can be utilized as a fluorescent probe to detect macrophage-rich atherosclerotic plaques, contributing to research in cardiovascular diseases and metabolic disorders. -
Dye
SYBR Green I Chloride is a versatile nucleic acid stain that primarily interacts with double-stranded DNA. It exhibits high fluorescence upon binding, making it an essential tool in quantitative PCR, gel electrophoresis, and various molecular biology applications. This dye is useful for visualizing and quantifying nucleic acids in research studies, enabling the analysis of gene expression, pathogen detection, and other genomic investigations. Additionally, its properties facilitate studies in cell biology and diagnostics, supporting a broad spectrum of scientific research and clinical applications. -
Fluorescent Membrane Probe
Merocyanin 540 is a fluorescent membrane probe that selectively labels the membranes of electrically excitable cells while excluding non-excitable cells (Ex/Em: 540/580 nm). This compound is particularly useful in studies involving neuronal activity and can aid in the visualization of membrane dynamics in various cell types. Its selective staining capabilities make it a valuable tool for researchers investigating membrane properties and excitability in cellular systems. -
DNA Fluorescent Dye
Methyl Green is a non-intercalating fluorescent dye that targets DNA by selectively binding to the major groove. It exhibits high affinity, resistance to photobleaching, and stable fluorescence emission, making it suitable for various applications. Methyl Green can be utilized for fluorescent labeling of nuclei in embryonic tissues or cells, as well as for DNA staining and assessing cell activity in gel electrophoresis. Its fluorescence peaks are observed at 633 nm and 677 nm, enabling direct measurement through microscopy and flow cytometry. -
NO Fluorescent Probe
1,2-Diaminoanthraquinone is a selective and nontoxic fluorescent probe for the detection of nitric oxide (NO). It demonstrates high sensitivity with a detection limit of 5 μM, making it suitable for measuring NO production in live cells and animal models. This compound absorbs maximally at approximately 540 nm, facilitating accurate imaging and analysis in various biological research applications. -
Fluorescent Probe
LysoTracker Yellow HCK 123 is a membrane-permeable fluorescent probe that selectively targets acidic cellular compartments. This compound is a weakly basic amine that accumulates in environments with low luminal pH, enabling researchers to visualize and study lysosomal dynamics and function. It is widely utilized in cellular imaging applications to investigate cellular processes such as autophagy, metabolism, and organelle dynamics. -
Fluorochrome
YO-PRO-1 is a green fluorescent dye designed for detecting apoptotic and necrotic cells through its inability to penetrate intact cell membranes. It exhibits a strong affinity for DNA; when bound, it emits a bright green fluorescence (Ex/Em: 488/530±30 nM), facilitating the identification of cellular states. YO-PRO-1 is commonly utilized in conjunction with other reagents, such as Propidium Iodide, enhancing the analysis of cell viability and apoptosis in various biological research applications. -
Potential-sensitive Fluorescence Dye
DiBAC4(5) is a voltage-sensitive fluorescent dye that targets changes in membrane potential. It is widely used to monitor transmembrane potentials in various cell types, including Papain-dissociated retinal cells from adult zebrafish in the presence of GABAergic ligands. This reagent facilitates the study of excitability and membrane dynamics, contributing to research on neuronal signaling and cell physiology. -
Mitochondrial Marker
4-Di-2-ASP is a styryl pyridinium fluorescent dye primarily used as a mitochondrial marker. This compound demonstrates reliable and specific labeling of neuroepithelial bodies (NEBs) in pulmonary tissues, facilitating the investigation of mitochondrial dynamics and cellular respiration. Its application is critical in studies aimed at understanding respiratory physiology and neuroepithelial signaling. -
Peroxynitrite Indicator
HKGreen-4I is a selective fluorescent probe for the detection of peroxynitrite (ONOO-) in living cells. With a maximum excitation wavelength of 520 nm and emission wavelength of 543 nm, this highly sensitive indicator enables real-time monitoring of oxidative stress. It is useful for research applications involving nitric oxide signaling, reactive oxygen species, and related cellular processes. -
Cationic Dye
Pyronin Y, a cationic dye, primarily targets RNA by intercalating with nucleic acids. This compound forms fluorescent complexes with double-stranded RNA, facilitating semi-quantitative analysis of cellular RNA levels. Pyronin Y is suitable for identifying specific RNA subspecies within ribonucleoprotein complexes in living cells, making it a valuable tool for studies in molecular biology and cellular research. -
Fluorescent Lipophilic Tracer
4-Di-10-ASP is a fluorescent lipophilic tracer that primarily targets phospholipid membranes with its excitation wavelength at 485 nm and emission at 620 nm. This compound is utilized for specific staining of cellular membranes, aiding in studies of membrane dynamics and organization. Its application is particularly valuable in cellular biology and neuroscience research, where visualization of lipid membrane structures is essential. -
Fluorescent Dye
Rhodamine 6G hydrazide is a fluorescent dye known for its strong absorbance and emission characteristics. It exhibits robust colorimetric and fluorescent properties, making it suitable for a variety of sensing applications. This reagent is commonly utilized in biochemical assays and imaging studies, facilitating the detection of specific biomolecules. -
H2S Fluorescent Probe
CAY10731 is a highly selective fluorescent probe designed for the detection of hydrogen sulfide (H2S). This compound enables precise monitoring of both exogenous and endogenous H2S levels in various cell types, including cancerous and normal cells. CAY10731 is also effective for imaging H2S in living tissues at different depths and is applicable in studies involving nematodes, advancing research in cellular signaling and physiology. -
Azo Dye
Methyl Orange is an azo dye primarily utilized as an acid-base indicator. It exhibits a color change from red at pH 3.1 to bright yellow at pH 4.4, facilitating its application in various pH-related experiments. In addition to its use in acid-base titrations, Methyl Orange is employed for cellular staining and dyeing textiles. Notably, at concentrations of 500 mg/L, it has been shown to exhibit cytotoxic effects and can induce DNA damage, making it relevant for studies in cytotoxicity and genotoxicity. -
NO Fluorescent Probe
RB-OPD is a nitric oxide (NO) fluorescent probe that utilizes an o-phenylenediamine (OPD) lock mechanism to enhance sensitivity and selectivity. With excitation and emission wavelengths of 550 nm and 590 nm, respectively, this probe is designed for reliable detection of NO in various biological systems. It is ideal for applications in cellular imaging and research on NO signaling pathways, providing valuable insights into nitric oxide's role in physiological and pathological processes. -
Fluorescent Dye
SPQ (Sodium Coumarin-3-Carboxylic Acid) is a fluorescent dye primarily utilized for measuring chloride ion concentrations and transport dynamics. This compound exhibits high sensitivity and specificity, making it suitable for studying chloride ion transients in vesicles, cells, and intact epithelial tissues. SPQ is an essential tool for researchers investigating chloride ion signaling and transport mechanisms in various biological systems. -
Dye
Eosin B (Acid Red 91) is a multifunctional dye that primarily serves as a vital tool in biological research. Its primary mechanism involves staining biological samples, enabling the visualization and analysis of cell structures, tracking of biomolecules, and evaluation of cell functions. Eosin B is instrumental in distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms, making it suitable for diverse applications in both fundamental scientific research and clinical diagnostics. Additionally, it finds utility in traditional textile dyeing and emerging areas such as food pigments and dye-sensitized solar cells. -
DNA Fluorescent Label
JOE is a fluorescent dye designed for use as a fluorescent label in various nucleic acid amplification techniques, including DNA sequencing, polymerase chain reaction (PCR), and ligase chain reaction (LCR). With an absorbance maximum at 525 nm and an emission maximum at 550 nm, JOE provides enhanced sensitivity and specificity for detecting DNA. This compound is essential for applications requiring precise monitoring of nucleic acid interactions and concentrations. -
Sphingomyelin Fluorescent Analogue
C6 NBD Sphingomyelin is a fluorescent analogue of sphingomyelin, designed to study lipid dynamics within cellular membranes. This compound serves as a valuable tool for investigating the incorporation of sphingomyelin into the plasma membrane and its behavior under various biological conditions. C6 NBD Sphingomyelin is particularly useful in research involving Chlamydia trachomatis, as it can be synthesized from C6-NBD-ceramide and localized within the chlamydial inclusion. Its fluorescent properties enable visualization and analysis of sphingomyelin metabolism and distribution in cellular processes. -
Metallochromic dye
Arsenazo III is a metallochromic dye that functions as a chelating agent and cation complexing agent. This compound forms stable 1:1 complexes with various cations, including Ca2+, Mg2+, Sr2+, Ba2+, K+, and Na+, with binding affinity influenced by pH and alkali metal cation concentration. Arsenazo III is widely utilized as a colorimetric indicator for the detection of micromolar levels of ionized calcium in cellular studies, making it a valuable tool in biochemical and physiological research. -
Fluorescent Probe
HKPerox-1 is a highly sensitive green fluorescent probe designed for the specific detection of hydrogen peroxide (H2O2) in living cells. It exhibits a maximum excitation wavelength of 520 nm and an emission wavelength of 543 nm, enabling effective visualization of oxidative stress and reactive oxygen species. This probe is ideal for research applications involving cellular metabolism, oxidative stress studies, and the assessment of redox biology in various experimental contexts. -
Selenol Fluorescent Probe
Sel-green is a selective selenol fluorescent probe designed to quantify selenium (Sec) content in selenoenzymes such as thioredoxin reductase. This reagent enables the imaging of endogenous Sec in live HepG2 cells, making it invaluable for studies focusing on selenium metabolism and its implications in cellular physiology. Researchers can utilize Sel-green to gain insights into the role of selenoenzymes in various biological processes and disease states. -
Fluorescent Mg2+ Probe
KMG-104 is a cell-impermeant fluorescent probe specifically designed for the selective detection of Mg2+ ions. This reagent enables real-time imaging of Mg2+ mobilization in the cytoplasm across various cell types, making it a valuable tool for studies involving cellular signaling and ion homeostasis. Its high specificity and sensitivity facilitate the exploration of magnesium's role in physiological and pathological processes. -
Fatty Acid Fluorescent Marker
C6-NBD Sphinganine is a fluorescent analog of sphinganine that serves as a potent fatty acid fluorescent marker. This compound enables the visualization and tracking of fatty acids in cellular and tissue studies, facilitating research in lipid metabolism and cellular signaling pathways. Its applications extend to studying lipid-related diseases and understanding the dynamics of sphingolipid metabolism. -
Cu2+ Fluorescent Dye
10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a highly sensitive fluorescent dye specifically designed for the detection of Cu2+ ions. This compound exhibits enhanced fluorescence properties upon binding to copper ions, making it a valuable tool for studying metal ion distribution and dynamics in biological systems. Its application extends to fluorescence imaging and sensing in various research contexts, including environmental monitoring and biological assays. -
Fluorescent Dye
Alexa Fluor 647 maleimide is a far-red-emitting fluorescent dye designed for the selective labeling of protein thiol groups, particularly cysteine residues (Ex/Em = 656/670 nm). This reagent facilitates the attachment of the AF 647 fluorophore to various biomolecules, including proteins, peptides, and thiol-containing oligonucleotides. Its exceptional brightness makes it valuable for applications in cell biology, neuroscience, and disease diagnostics, enabling advanced fluorescence imaging and analysis. -
Mg2+ Fluorescent Probe
KMG-301AM TFA is an acetoxymethyl ester derivative of KMG-301, designed as a fluorescent probe targeting Mg2+ within mitochondria. Once inside the mitochondria, it is hydrolyzed to KMG-301, which selectively measures Mg2+ concentrations in live cells, as it remains confined within the mitochondria due to the impermeability of the mitochondrial membrane. This probe is suitable for assessing Mg2+ transport and monitoring changes in mitochondrial Mg2+ levels, providing valuable insights in cellular models of mitochondrial function and dysfunction. -
Fluorescent Dye
BHQ-1 NHS is a fluorescent dye designed for efficient labeling of nucleotide sequences. This compound serves as a quencher, offering enhanced fluorescence signaling for applications in nucleic acid research and diagnostics. BHQ-1 NHS is particularly valuable in the development of real-time PCR assays and other molecular biology techniques requiring precise fluorescence modulation. -
Fluorescent Dye
H-FluNox is a selective fluorescent probe designed to detect labile heme through biomimetic N-oxide deoxygenation, which activates its fluorescence. This compound demonstrates over 100-fold selectivity for labile heme compared to Fe(II), facilitating the differentiation of labile heme from intracellular Fe(II) pools. H-FluNox's high sensitivity enables the detection of labile heme at the subcellular level, making it an invaluable tool for studies of heme dynamics and related biological processes. -
Fluorescent Dye
MitoMark Red I is a fluorescent dye specifically designed to target mitochondria in viable cells. This red fluorescent marker exhibits a peak excitation wavelength of 578 nm and an emission at 599 nm, enabling precise visualization of mitochondrial activity and dynamics. It is widely utilized in cellular and molecular biology research to study mitochondrial function, cell viability, and related physiological processes. -
HOCl Fluorescent Probe
EtS-DMAB is a fluorescent probe designed for the selective detection of hypochlorous acid (HOCl). Exhibiting fluorescence with excitation at 440 nm and emission at 610 nm, it is used to visualize both exogenous and endogenous levels of HOCl in live cells. This compound is valuable for studies involving oxidative stress and inflammation, providing insights into cellular responses under specific pathological conditions. -
Fluorescent Dye
DHPDS disodium salt is a pH-sensitive fluorescent dye that enables the measurement of intracellular pH (pHi). This compound is particularly useful in experimental setups involving isolated perfused rat liver, where it facilitates the assessment of pH variations through surface fluorescence. Its application extends to various biological studies requiring precise pH measurements in living cells. -
Fluorescent Substrate
Z-VEID-AFC is a fluorescent substrate specifically designed for the detection of caspase-6 activity. Upon cleavage by active caspase-6, it releases a fluorescent signal, making it useful for monitoring apoptotic processes in various biological systems. This reagent serves as a valuable tool in studies related to cell death, neurodegeneration, and tumor biology, facilitating the investigation of caspase-related pathways in research applications. -
Fluorescent Dye
R-Phycoerythrin (R-PE) is an orange-red fluorescent dye derived from the red algae Heterosiphonia japonica. This fluorescent probe consists of α, β, and γ subunits and is widely utilized in fluorescence microscopy, flow cytometry, and immunofluorescence analysis, with an excitation wavelength of 495 nm. Additionally, R-PE is employed in photodynamic therapy (PDT) for inducing apoptosis in tumor cells, making it a valuable tool in cancer research and diagnostics. -
Bacterial Growth Probing
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue-emitting (λem ≈ 450 nm) fluorescent D-amino acid (FDAA) used for labeling bacterial cell walls. FDAAs are incorporated into peptidoglycan (PG) at sites of active biosynthesis through the action of native transpeptidases, enabling specific and covalent labeling of growing bacterial cells with minimal disruption to normal physiology. HADA hydrochloride provides high spatial and temporal resolution for visualizing bacterial growth dynamics, cell wall synthesis, and morphogenesis in live-cell imaging studies, making it a powerful tool in microbiology and antibiotic mechanism research. -
Chemiluminescent Probe
L-012 sodium salt is a luminol-based chemiluminescent probe widely used for the sensitive detection of reactive oxygen and nitrogen species (ROS and RNS) in biological systems. It is particularly effective in monitoring NADPH oxidase (Nox)-derived superoxide production, providing high signal intensity and low background interference. Compared with conventional luminol, L-012 offers enhanced chemiluminescence sensitivity and stability, enabling real-time detection of oxidative and nitrosative stress in cells, tissues, and *in vivo* models. It is a valuable tool for studying redox signaling, inflammation, and oxidative stress–related pathophysiology. -
Lipid Droplets Probe
BODIPY 558/568 C12 is a fluorescent lipid probe based on the BODIPY (boron-dipyrromethene) dye structure. BODIPY dyes are small-molecule fluorophores characterized by strong ultraviolet-visible absorption, sharp fluorescence emission peaks, high quantum yields, and remarkable photostability. They are largely insensitive to environmental polarity and pH, maintaining consistent fluorescence under various physiological conditions. BODIPY 558/568 C12, due to its lipophilic alkyl chain, readily permeates cell membranes and specifically localizes to neutral lipid compartments, enabling selective staining of lipid droplets in both live and fixed cells. It serves as a reliable fluorescent marker for studying lipid metabolism, lipid droplet dynamics, and cellular lipid distribution. The dye exhibits maximum excitation and emission wavelengths at 558 nm and 568 nm, respectively. -
Biochemical Assay Reagent
Rhodamine B isothiocyanate (RBITC) is a reactive fluorescent dye widely used for covalent labeling of biomolecules in imaging and analytical applications. The isothiocyanate functional group readily reacts with primary amines on proteins, peptides, and other biomolecules to form stable thiourea linkages, enabling durable fluorescent tagging. RBITC emits bright orange-red fluorescence upon green light excitation, providing strong signal intensity and excellent photostability for visualization in complex biological systems. Owing to its high sensitivity, chemical stability, and compatibility with diverse assay conditions, RBITC is extensively utilized in cell biology, immunology, neurobiology, and fluorescence microscopy studies for tracking molecular localization and dynamics. -
Fluorochrome
WSP-5 is a selective fluorescent probe designed for rapid detection of hydrogen sulfide (H₂S) in biological samples and live cells. It operates via a reaction-based “fluorescence turn-on” mechanism, in which WSP-5 reacts specifically and swiftly with H₂S to generate a highly fluorescent product. The probe exhibits excitation and emission maxima at 502 nm and 525 nm, respectively. Due to its excellent selectivity, sensitivity, and biocompatibility, WSP-5 is widely used in studies of H₂S biology, cellular signaling, and redox homeostasis. -
Amino Acid Sequence Detection Reagent
AQC (6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate) is a highly sensitive derivatization reagent used for amino acid and peptide analysis by high-performance liquid chromatography (HPLC) with fluorescence detection. It reacts rapidly with both primary and secondary amino groups to form stable fluorescent derivatives, enabling detection of amino acids at sub-picomolar concentrations. Due to its high reactivity, stability, and strong fluorescence yield, AQC is widely applied in protein sequencing, amino acid quantification, and metabolic profiling, providing exceptional sensitivity and reproducibility in analytical and biochemical studies. -
Fluorescent Dye
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a thiol-reactive fluorescent dye widely used for covalent labeling of proteins, peptides, and other biomolecules containing cysteine residues. By forming stable thioether bonds with sulfhydryl groups, it enables precise detection and quantification of thiol-containing targets. Fluorescein-5-maleimide is employed to monitor the redox state of thiols in eukaryotic cells, label peptides or actin for protein–protein interaction studies—such as investigations of actin binding to cardiac myosin-binding protein C (cMyBP-C)—and to detect negatively charged nanoparticles. It also serves as a tool for screening mutant proteins containing cysteine residues. The dye exhibits strong fluorescence with excitation and emission maxima at 494 nm and 519 nm, respectively, making it highly suitable for fluorescence microscopy, flow cytometry, and biochemical assays. -
Azo Dye
Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active synthetic azo dye that appears as an orange-yellow, water-soluble powder producing a bright yellow coloration in solution. It is widely used as a food colorant and in pharmaceuticals and cosmetics due to its high chemical and photostability. Beyond its industrial applications, Tartrazine has been reported to induce mitochondria-mediated apoptosis and to exhibit potential biological effects, including neurodevelopmental toxicity, cytotoxicity, and genotoxicity under certain experimental conditions. It serves as a model compound in toxicological and biochemical studies investigating the safety and cellular impact of synthetic food dyes.
