Catalog No.
Product Name
Application
Product Information
Citations
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Neuronal Retrograde Tracer
True Blue is a fluorescent dye that serves as a neuronal retrograde tracer, excitable within the 395-425 nm wavelength range, with an emission barrier filter of 450 nm. It effectively labels neurons without compromising their survival, making it suitable for applications in neuronal tracing and mapping studies. This reagent is valuable for understanding neural connectivity and function in various research settings. -
DNA Dye
DAPI (4',6-Diamidino-2-phenylindole) is a fluorescent DNA dye that selectively binds to the AT base pairs in the minor groove of double-stranded DNA, enhancing fluorescence intensity approximately 20-fold upon binding. This property makes DAPI suitable for applications in fluorescence microscopy, allowing for quantification of DNA based on fluorescence intensity. Additionally, DAPI's ability to penetrate intact cell membranes enables its use in staining both live and fixed cells. DAPI also acts as an inhibitor of acid-sensing ion channel 3 (ASIC3), potentially contributing to research in chronic pain treatment (Ex/Em = 356/451 nm). -
Aluminum Ion Fluorescent Dyes
Lumogallion is a selective fluorescent reagent designed for the detection of aluminum ions, gallium, and other metal ions. Its high sensitivity allows for precise quantification and visualization in various biological and environmental samples. With an excitation wavelength of 490 nm and an emission spectrum ranging from 520 nm to 650 nm, Lumogallion exhibits a peak emission at approximately 580 nm, making it suitable for fluorescence-based applications in chemical research and analytical studies. -
Organic Anion Dye
Sulfobromophthalein disodium salt is an organic anion dye primarily utilized to investigate membrane carriers in animal tissues. This compound plays a critical role in understanding the transport mechanisms of various agents and metabolites across cell membranes. Its applications extend to studies related to pharmacokinetics and drug absorption, making it a valuable tool for researchers in the fields of biochemistry and pharmacology. -
Fluorescent Dye
DCVJ (9-(2,2-Dicyanovinyl)julolidine) is a unique fluorescent dye known for its ability to act as a molecular rotor. It exhibits significantly enhanced fluorescence intensity upon the polymerization of tubulin and actin, making it a valuable tool for studying cytoskeletal dynamics. Additionally, DCVJ interacts with phospholipid bilayers, further amplifying fluorescence. This compound is applicable in research involving mast cell degranulation, with optimal absorption and emission spectra at 489 nm and 505 nm, respectively. -
Fluorescent Imaging Agent
Pafolacianine is a near-infrared fluorescent imaging agent utilized for the detection of tumor lesions during surgical interventions. This compound operates by exciting at wavelengths of 774 to 775 nm and emitting at 794 to 796 nm, allowing for enhanced visualization of tumor tissues. Its application in intraoperative imaging significantly aids in improving surgical outcomes by providing real-time feedback for tumor localization. -
H2O2 Fluorescent Probe
HKPerox-2 is a highly sensitive fluorescent probe specifically designed for the detection of hydrogen peroxide (H2O2) in live cells. It exhibits peak excitation and emission wavelengths at 520 nm and 543 nm, respectively, making it suitable for fluorescence microscopy applications. This reagent can be utilized to study oxidative stress and cellular signaling involving reactive oxygen species, enabling insights into various biological processes and disease mechanisms. -
Fluorescent Dye
CellTracker Blue CMF2HC Dye is a fluorescent dye primarily used for visualizing and tracking live cells. It emits a blue fluorescence when excited at wavelengths between 450-460 nm, making it suitable for applications such as two-channel nucleic acid sequencing. Additionally, this dye facilitates the rapid assessment of microbial antibiotic sensitivity, providing valuable insights for microbiological research. -
Phospholipid Fluorescent Probe
BODIPY FL-DHPE is a green-fluorescent phospholipid probe targeting lipid bilayers. It labels 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), facilitating the study of membrane dynamics through membrane fusion processes. This reagent is ideal for investigating membrane structure and function in various cellular contexts, as well as analyzing lipid interactions in live cell imaging applications. The excitation and emission wavelengths are λex=505 nm and λem=511 nm, respectively. -
Cationic Carbocyanine Dye
Stains-All is a cationic carbocyanine dye that serves as an effective probe for investigating the structural characteristics of individual calcium-binding sites within calmodulin (CaM) and other related calcium-binding proteins (CaBP). This dye facilitates the study of calcium-binding interactions, making it an invaluable tool in cellular and molecular biology research focused on calcium signaling pathways and protein interactions. -
Oxidized Fluorescent Product
2',7'-Dichlorofluorescein is a potent fluorescent probe primarily used for the detection of oxidative stress by quantifying reactive oxygen species (ROS) levels. It exhibits excitation and emission maxima at 503 nm and 523 nm, respectively. This compound is essential for applications in cellular biology and biochemistry, enabling researchers to study oxidative damage and its effects on biological systems. -
OH Indicator
HKOH-1r is a highly sensitive green fluorescent probe designed for the selective detection of hydroxyl radicals (·OH) in living cells. It exhibits excitation and emission maxima at 500 nm and 520 nm, respectively, facilitating real-time visualization of oxidative stress. This reagent is applicable in various research settings, including studies focused on cellular redox status and oxidative damage pathways. -
Fluorescent Probe
DASPEI is a cationic styrenyl dye that targets mitochondria, functioning as a fluorescent probe with a large Stokes shift. Exhibiting excitation and emission wavelengths of 550 nm and 573 nm respectively, DASPEI demonstrates excellent photostability and labeling capability. This reagent effectively stains mitochondria in living cells and can also label presynaptic nerve endings, providing insights into cellular and synaptic activity. Its applications are valuable in various fields including neurobiology and cellular imaging research. -
Microenvironment-sensitive Membrane Reporter
Prodan is a solvatochromic fluorophore that serves as a microenvironment-sensitive membrane reporter. Its unique properties allow for the detection of changes in the local environment of membranes by varying Stokes shift values in response to the orientational polarizability of solvents. This versatility makes Prodan an essential tool in the study of membrane dynamics and the characterization of fluorescent nucleosides. It is particularly useful in applications involving membrane biophysics and the assessment of lipid bilayer properties. -
Fluorescent Dye
6-CFDA is a fluorescent dye commonly used in biological research for cell tracking and viability assays. It undergoes free diffusion into cells, where it is hydrolyzed by intracellular non-specific lipases to produce carboxyfluorescein, a fluorescent compound that carries an additional negative charge. This enhanced charge improves retention within cells compared to traditional fluorescein dyes, facilitating more accurate analysis of cellular processes and functions. -
Fluorescent Marker
6-ROX is a selective fluorescent probe targeting cyclooxygenase-2 (COX-2). By binding to the active site of COX-2, it inhibits the conversion of arachidonic acid to prostaglandins, making it an essential tool for studying COX-2-related pathways. 6-ROX is widely utilized in optical imaging applications aimed at identifying tumors and inflamed tissues that exhibit elevated COX-2 expression. -
Fluorescent pH Indicator
OG 488, SE (Oregon Green 488 succinimidyl ester) is a fluorescent pH indicator that exhibits strong fluorescence properties. It is widely utilized in biochemistry and neurosciences for various applications, including cellular imaging and tracking pH changes in live cells. Its ability to provide real-time pH measurements makes it an invaluable tool for researchers studying cellular processes and physiological conditions. -
Fluorogenic Probe
HKYellow-AM (6/12-mixture) is a fluorogenic probe designed for the selective and sensitive detection of peroxynitrite (ONOO-) in living cells and tissues. This probe offers a non-cytotoxic option for real-time fluorescence imaging, enabling researchers to investigate oxidative stress and related pathophysiological processes. Its high selectivity allows for accurate assessment of ONOO- levels, making it a valuable tool for studies in cellular signaling and antioxidant defense mechanisms. -
Fluorescent Probe
5-CFDA-AM is a fluorescent probe designed to measure enzyme activity and assess cell membrane integrity. This cell-permeable esterase substrate enters cells efficiently and is hydrolyzed by intracellular esterases to form carboxyfluorescein, which exhibits enhanced retention due to its negative charge. Its quantitative fluorescence capacity makes it a valuable tool for various biological research applications, including studies on cellular processes and viability assessments. -
Histochemical Stain
X-34 is a lipophilic fluorescent derivative of Congo red, characterized by its bright yellow-green fluorescence. It selectively stains neuritic and diffuse plaques, neurofibrillary tangles, neuropil threads, and cerebrovascular amyloid in brain tissue. This reagent is widely utilized in research focused on Alzheimer's disease to facilitate the study of these key pathological features. -
Fluorophore
6-HEX is a fluorophore characterized by its excitation and emission wavelengths of 532 nm and 556 nm, respectively. It is particularly effective for recording nucleic acid sequences and is useful in the design of optical materials. Additionally, 6-HEX can be employed to visualize nucleic acids under 543 nm radiation, as well as to directly locate cell group bases using 550 nm and 650 nm wavelengths. -
Fluorescent Dye
ANTS is a fluorescent dye characterized by an excitation wavelength of 380 nm and an emission wavelength of 520 nm. This compound is utilized for assessing membrane integrity, particularly in studies involving liposomal formulations, where it effectively measures membrane leakage when encapsulated alongside DPX. ANTS is a valuable tool in biochemical and cellular research applications that require precise monitoring of membrane dynamics. -
Fluorescent Dye
Phenazine ethosulfate is a cationic fluorescent dye characterized by an excitation wavelength of 390 nm and an emission wavelength of 530 nm. This compound serves as an electron acceptor and is utilized in dye-linked enzyme assays. It is particularly effective in detecting nitric oxide reductase (Nors) activity in conjunction with ascorbic acid, making it valuable for biochemical research involving enzyme functions and redox reactions. -
Fluorescent Dye
6-NBDG is a fluorescent glucose analogue that selectively targets glucose transport mechanisms. It serves as an effective tool for fluorescence imaging, enabling the monitoring of glucose uptake in various biological contexts. Additionally, 6-NBDG can be utilized as a fluorescent probe to detect macrophage-rich atherosclerotic plaques, contributing to research in cardiovascular diseases and metabolic disorders. -
Dye
SYBR Green I Chloride is a versatile nucleic acid stain that primarily interacts with double-stranded DNA. It exhibits high fluorescence upon binding, making it an essential tool in quantitative PCR, gel electrophoresis, and various molecular biology applications. This dye is useful for visualizing and quantifying nucleic acids in research studies, enabling the analysis of gene expression, pathogen detection, and other genomic investigations. Additionally, its properties facilitate studies in cell biology and diagnostics, supporting a broad spectrum of scientific research and clinical applications. -
Fluorescent Membrane Probe
Merocyanin 540 is a fluorescent membrane probe that selectively labels the membranes of electrically excitable cells while excluding non-excitable cells (Ex/Em: 540/580 nm). This compound is particularly useful in studies involving neuronal activity and can aid in the visualization of membrane dynamics in various cell types. Its selective staining capabilities make it a valuable tool for researchers investigating membrane properties and excitability in cellular systems. -
DNA Fluorescent Dye
Methyl Green is a non-intercalating fluorescent dye that targets DNA by selectively binding to the major groove. It exhibits high affinity, resistance to photobleaching, and stable fluorescence emission, making it suitable for various applications. Methyl Green can be utilized for fluorescent labeling of nuclei in embryonic tissues or cells, as well as for DNA staining and assessing cell activity in gel electrophoresis. Its fluorescence peaks are observed at 633 nm and 677 nm, enabling direct measurement through microscopy and flow cytometry. -
NO Fluorescent Probe
1,2-Diaminoanthraquinone is a selective and nontoxic fluorescent probe for the detection of nitric oxide (NO). It demonstrates high sensitivity with a detection limit of 5 μM, making it suitable for measuring NO production in live cells and animal models. This compound absorbs maximally at approximately 540 nm, facilitating accurate imaging and analysis in various biological research applications. -
Fluorescent Probe
LysoTracker Yellow HCK 123 is a membrane-permeable fluorescent probe that selectively targets acidic cellular compartments. This compound is a weakly basic amine that accumulates in environments with low luminal pH, enabling researchers to visualize and study lysosomal dynamics and function. It is widely utilized in cellular imaging applications to investigate cellular processes such as autophagy, metabolism, and organelle dynamics. -
Fluorochrome
YO-PRO-1 is a green fluorescent dye designed for detecting apoptotic and necrotic cells through its inability to penetrate intact cell membranes. It exhibits a strong affinity for DNA; when bound, it emits a bright green fluorescence (Ex/Em: 488/530±30 nM), facilitating the identification of cellular states. YO-PRO-1 is commonly utilized in conjunction with other reagents, such as Propidium Iodide, enhancing the analysis of cell viability and apoptosis in various biological research applications. -
Potential-sensitive Fluorescence Dye
DiBAC4(5) is a voltage-sensitive fluorescent dye that targets changes in membrane potential. It is widely used to monitor transmembrane potentials in various cell types, including Papain-dissociated retinal cells from adult zebrafish in the presence of GABAergic ligands. This reagent facilitates the study of excitability and membrane dynamics, contributing to research on neuronal signaling and cell physiology. -
Mitochondrial Marker
4-Di-2-ASP is a styryl pyridinium fluorescent dye primarily used as a mitochondrial marker. This compound demonstrates reliable and specific labeling of neuroepithelial bodies (NEBs) in pulmonary tissues, facilitating the investigation of mitochondrial dynamics and cellular respiration. Its application is critical in studies aimed at understanding respiratory physiology and neuroepithelial signaling. -
Peroxynitrite Indicator
HKGreen-4I is a selective fluorescent probe for the detection of peroxynitrite (ONOO-) in living cells. With a maximum excitation wavelength of 520 nm and emission wavelength of 543 nm, this highly sensitive indicator enables real-time monitoring of oxidative stress. It is useful for research applications involving nitric oxide signaling, reactive oxygen species, and related cellular processes. -
Cationic Dye
Pyronin Y, a cationic dye, primarily targets RNA by intercalating with nucleic acids. This compound forms fluorescent complexes with double-stranded RNA, facilitating semi-quantitative analysis of cellular RNA levels. Pyronin Y is suitable for identifying specific RNA subspecies within ribonucleoprotein complexes in living cells, making it a valuable tool for studies in molecular biology and cellular research. -
Fluorescent Lipophilic Tracer
4-Di-10-ASP is a fluorescent lipophilic tracer that primarily targets phospholipid membranes with its excitation wavelength at 485 nm and emission at 620 nm. This compound is utilized for specific staining of cellular membranes, aiding in studies of membrane dynamics and organization. Its application is particularly valuable in cellular biology and neuroscience research, where visualization of lipid membrane structures is essential. -
Fluorescent Dye
Rhodamine 6G hydrazide is a fluorescent dye known for its strong absorbance and emission characteristics. It exhibits robust colorimetric and fluorescent properties, making it suitable for a variety of sensing applications. This reagent is commonly utilized in biochemical assays and imaging studies, facilitating the detection of specific biomolecules. -
H2S Fluorescent Probe
CAY10731 is a highly selective fluorescent probe designed for the detection of hydrogen sulfide (H2S). This compound enables precise monitoring of both exogenous and endogenous H2S levels in various cell types, including cancerous and normal cells. CAY10731 is also effective for imaging H2S in living tissues at different depths and is applicable in studies involving nematodes, advancing research in cellular signaling and physiology. -
Azo Dye
Methyl Orange is an azo dye primarily utilized as an acid-base indicator. It exhibits a color change from red at pH 3.1 to bright yellow at pH 4.4, facilitating its application in various pH-related experiments. In addition to its use in acid-base titrations, Methyl Orange is employed for cellular staining and dyeing textiles. Notably, at concentrations of 500 mg/L, it has been shown to exhibit cytotoxic effects and can induce DNA damage, making it relevant for studies in cytotoxicity and genotoxicity. -
NO Fluorescent Probe
RB-OPD is a nitric oxide (NO) fluorescent probe that utilizes an o-phenylenediamine (OPD) lock mechanism to enhance sensitivity and selectivity. With excitation and emission wavelengths of 550 nm and 590 nm, respectively, this probe is designed for reliable detection of NO in various biological systems. It is ideal for applications in cellular imaging and research on NO signaling pathways, providing valuable insights into nitric oxide's role in physiological and pathological processes. -
Fluorescent Dye
SPQ (Sodium Coumarin-3-Carboxylic Acid) is a fluorescent dye primarily utilized for measuring chloride ion concentrations and transport dynamics. This compound exhibits high sensitivity and specificity, making it suitable for studying chloride ion transients in vesicles, cells, and intact epithelial tissues. SPQ is an essential tool for researchers investigating chloride ion signaling and transport mechanisms in various biological systems. -
Dye
Eosin B (Acid Red 91) is a multifunctional dye that primarily serves as a vital tool in biological research. Its primary mechanism involves staining biological samples, enabling the visualization and analysis of cell structures, tracking of biomolecules, and evaluation of cell functions. Eosin B is instrumental in distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms, making it suitable for diverse applications in both fundamental scientific research and clinical diagnostics. Additionally, it finds utility in traditional textile dyeing and emerging areas such as food pigments and dye-sensitized solar cells. -
DNA Fluorescent Label
JOE is a fluorescent dye designed for use as a fluorescent label in various nucleic acid amplification techniques, including DNA sequencing, polymerase chain reaction (PCR), and ligase chain reaction (LCR). With an absorbance maximum at 525 nm and an emission maximum at 550 nm, JOE provides enhanced sensitivity and specificity for detecting DNA. This compound is essential for applications requiring precise monitoring of nucleic acid interactions and concentrations. -
Sphingomyelin Fluorescent Analogue
C6 NBD Sphingomyelin is a fluorescent analogue of sphingomyelin, designed to study lipid dynamics within cellular membranes. This compound serves as a valuable tool for investigating the incorporation of sphingomyelin into the plasma membrane and its behavior under various biological conditions. C6 NBD Sphingomyelin is particularly useful in research involving Chlamydia trachomatis, as it can be synthesized from C6-NBD-ceramide and localized within the chlamydial inclusion. Its fluorescent properties enable visualization and analysis of sphingomyelin metabolism and distribution in cellular processes. -
Metallochromic dye
Arsenazo III is a metallochromic dye that functions as a chelating agent and cation complexing agent. This compound forms stable 1:1 complexes with various cations, including Ca2+, Mg2+, Sr2+, Ba2+, K+, and Na+, with binding affinity influenced by pH and alkali metal cation concentration. Arsenazo III is widely utilized as a colorimetric indicator for the detection of micromolar levels of ionized calcium in cellular studies, making it a valuable tool in biochemical and physiological research. -
Fluorescent Probe
HKPerox-1 is a highly sensitive green fluorescent probe designed for the specific detection of hydrogen peroxide (H2O2) in living cells. It exhibits a maximum excitation wavelength of 520 nm and an emission wavelength of 543 nm, enabling effective visualization of oxidative stress and reactive oxygen species. This probe is ideal for research applications involving cellular metabolism, oxidative stress studies, and the assessment of redox biology in various experimental contexts. -
Selenol Fluorescent Probe
Sel-green is a selective selenol fluorescent probe designed to quantify selenium (Sec) content in selenoenzymes such as thioredoxin reductase. This reagent enables the imaging of endogenous Sec in live HepG2 cells, making it invaluable for studies focusing on selenium metabolism and its implications in cellular physiology. Researchers can utilize Sel-green to gain insights into the role of selenoenzymes in various biological processes and disease states. -
Fluorescent Mg2+ Probe
KMG-104 is a cell-impermeant fluorescent probe specifically designed for the selective detection of Mg2+ ions. This reagent enables real-time imaging of Mg2+ mobilization in the cytoplasm across various cell types, making it a valuable tool for studies involving cellular signaling and ion homeostasis. Its high specificity and sensitivity facilitate the exploration of magnesium's role in physiological and pathological processes. -
Fatty Acid Fluorescent Marker
C6-NBD Sphinganine is a fluorescent analog of sphinganine that serves as a potent fatty acid fluorescent marker. This compound enables the visualization and tracking of fatty acids in cellular and tissue studies, facilitating research in lipid metabolism and cellular signaling pathways. Its applications extend to studying lipid-related diseases and understanding the dynamics of sphingolipid metabolism. -
Cu2+ Fluorescent Dye
10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a highly sensitive fluorescent dye specifically designed for the detection of Cu2+ ions. This compound exhibits enhanced fluorescence properties upon binding to copper ions, making it a valuable tool for studying metal ion distribution and dynamics in biological systems. Its application extends to fluorescence imaging and sensing in various research contexts, including environmental monitoring and biological assays. -
Fluorescent Dye
Alexa Fluor 647 maleimide is a far-red-emitting fluorescent dye designed for the selective labeling of protein thiol groups, particularly cysteine residues (Ex/Em = 656/670 nm). This reagent facilitates the attachment of the AF 647 fluorophore to various biomolecules, including proteins, peptides, and thiol-containing oligonucleotides. Its exceptional brightness makes it valuable for applications in cell biology, neuroscience, and disease diagnostics, enabling advanced fluorescence imaging and analysis.
