Catalog No.
Product Name
Application
Product Information
Citations
- Hoechst 33258 analog 5 is a analog of Hoechst stains, which are part of a family of blue fluorescent dyes used to stain DNA.
- Hoechst 33258 analog 6 is a anglog of Hoechst stains(Hoechst 33258), which are part of a family of blue fluorescent dyes used to stain DNA.
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Blue fluorescent dyes
Hoechst 33342 analog is a nalog of Hoechst stains, which are part of a family of blue fluorescent dyes used to stain DNA. -
Blue fluorescent dyes
Hoechst 33342 analog 2 is a anglog of Hoechst stains, which are part of a family of blue fluorescent dyes used to stain DNA. - Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.
- Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA. Hoechst 33258 is a cell dye for DNA quantitation.
- Crystal violet is a triarylmethane dye. The dye is used as a histological stain and in Gram??s method of classifying bacteria.
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Fluorescent Peptide Substrate
Z-Val-Val-Arg-AMC is a fluorescent peptide substrate specifically designed for the assessment of cathepsin enzyme activity. This compound exhibits a high degree of specificity, facilitating the study of cathepsin-mediated biological processes. It is valuable in research applications involving proteolytic activity and enzyme kinetics, enabling researchers to investigate the roles of cathepsins in various physiological and pathological conditions. -
Fluorescent Substrate Analog
Guanosine 5'-triphosphate-5'-adenosine (GpppA) serves as a fluorescent substrate analog targeting RNA synthesis in vitro. As a 5′ cap analog, it plays a pivotal role in facilitating the incorporation of nucleotides during RNA transcription and can be utilized in various research applications, including studies of mRNA capping and translation initiation. -
Fluorescent Probe
Dihydrorhodamine 6G (DHR 6G) serves as a fluorescent probe targeting mitochondrial membranes. This nonfluorescent compound easily penetrates cells and is oxidized by reactive oxidative species or cellular redox systems, converting into the fluorescent rhodamine 6G. DHR 6G is valuable for the detection of reactive oxygen species (ROS), including superoxide, making it a crucial tool for research involving oxidative stress and mitochondrial function. -
Dye Tethered Hsp90 Inhibitor
HS-131 is a dye-tethered inhibitor that targets heat shock protein 90 (Hsp90). This compound exhibits the ability to selectively bind to and inhibit Hsp90, facilitating the detection of oncogene-driven breast cancers across various molecular subtypes. HS-131 is a valuable research tool for studying the role of Hsp90 in cancer biology and for developing novel therapeutic strategies targeting breast cancer. -
Diazo Dye
Fast Blue B Salt is a diazo dye that serves as a chromogenic substrate in biochemical analysis. It acts as a coupling agent for histochemical demonstration of proteases, facilitating the detection of acid phosphatase in Clostridium perfringens and the determination of lipase activity. Additionally, Fast Blue B Salt directly reacts with active hydroxyl groups in phenolic compounds, allowing for the quantification of phenolic substances. -
Fluorescent Fatty Acid
12-NBD Stearate is a fluorescent fatty acid analogue that targets fatty acid binding proteins (FABPs) and sterol carrier protein-2 (SCP-2). Its ability to bind to these proteins enhances the transport of long-chain fatty acids, particularly in systems overexpressing SCP-2 isoforms. This reagent serves as a valuable tool for studying the uptake and internalization of long-chain fatty acids through microscopic techniques, facilitating insights into lipid metabolism and transport mechanisms. -
ALP Fluorescent Probe
ALP Green is an amphiphilic fluorescent probe designed for detecting alkaline phosphatase (ALP) activity, with an emission wavelength of 550 nm. This probe is particularly useful in studying liver injury induced by acetaminophen (APAP) through its specific interaction with ALP. Researchers can utilize ALP Green to gain insights into liver function and enzyme activity in various biological assays. -
Fluorescent Dye
Complex 3 is a fluorescent dithiocarbazate-copper complex targeting mitochondrial function, demonstrating significant anticancer properties. It exhibits excitation and emission maxima of 455-495 nm and 535 nm, respectively. Complex 3 effectively inhibits the proliferation of several pancreatic cancer cell lines, including BxPC-3, AsPC-1, PANC-1, and WI38, with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. Additionally, it induces lipid peroxidation, mitochondrial rupture, and apoptosis, while also disrupting cytokine-cytokine receptor interactions in AsPC-1 cells. In vivo, Complex 3 has demonstrated efficacy by reducing tumor volume in an AsPC-1 mouse xenograft model, making it a valuable tool for cancer research. -
Geldanamycin Fluorescent Probe
Geldanamycin-FITC is a fluorescent probe that specifically targets HSP90. This compound enables the evaluation of HSP90 inhibitors through fluorescence polarization assays and can effectively detect cell surface HSP90 with an excitation/emission wavelength of 488/515 nm. It serves as a valuable tool in understanding HSP90-related biological processes and evaluating therapeutic interventions in diseases associated with this chaperone protein. -
Fluorescently-tethered Hsp90 Inhibitor
HS-27 is a fluorescently-tethered inhibitor targeting Heat Shock Protein 90 (Hsp90), facilitating the assessment of surface Hsp90 expression on intact tissue specimens. Comprising core elements of SNX-5422 linked through a PEG spacer to a fluorescein derivative, HS-27 selectively binds to ectopically expressed Hsp90. This reagent is particularly valuable in breast cancer research, providing a tool for applications involving visualization and treatment strategies. -
Magenta Dye
Fuchsine base monohydrochloride is a triaminotriphenylmethane dye known for its application as a magenta dye. It exhibits notable bactericidal, fungicidal, and anesthetic properties, making it valuable in various biological studies. This reagent can effectively stain collagen, muscle tissue, mitochondria, and is particularly useful in highlighting tuberculosis during microscopy. Additionally, Fuchsine base monohydrochloride serves as a reliable counterstain in Gram staining procedures, enhancing the differentiation of microbial cell walls. -
Photosensitive Dye
Rose Bengal is a water-soluble photosensitive dye exhibiting significant antibacterial activity through both dark-state and light-activated mechanisms. It demonstrates lethal photodynamic effects against S. carlsbergensis under aerobic light conditions while also inhibiting the growth of S. aureus in the dark. Furthermore, Rose Bengal restricts colony size in filamentous fungi and suppresses the growth of diffusive fungi. This compound is valuable for research related to infections and photodynamic therapy applications. - Cy3 NHS (Cyanine3 NHS ester) is a water-soluble and yellow emitting fluorescent dye for labeling amino-groups in biomolecules. Used to label soluble proteins, peptides, and oligonucleotides/DNA.
- Coumarin 30 is useful as laser dye. Efficient laser dye for pulsed and CW operation.
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fluorescent dye
Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group. -
Fluorescent P450 substrate
3-Cyano-7-ethoxycoumarin is a fluorogenic substrate suitable for the continuous determination of cytochrome P450 mixed-function monooxygenases. It is a fluorescent probe useful in microsomal dealkylase studies. -
luciferases substrate
D-Luciferin sodium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects. -
cellular ribonucleases inhibitor
Hydroxystilbamidine bis(methanesulfonate), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases. -
luciferin analogue
Aka Lumine, a luciferin analogue, is a luciferase substrate emitting red, green, and blue light. The longest emission wavelength of Aka Lumine is recorded at 675 nm, which is within the NIR region. -
colorimetric agent
Thiazolyl Blue (MTT) is a colorimetric agent widely used to measure cell proliferation. Thiazolyl Blue (MTT) is reduced from yellow color to purple formazan in living cells. - Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm.
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Fluorescent Dye
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity. -
Fluorescent Dye
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1. -
fluorescent probe
DAPI Dihydrochloride is a cell-permeable fluorescent probe used to stain DNA and chromosomes, with a preference for adenine and thymine rich DNA. -
active oxygen formation inducer
Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes. -
mono-stryryl dye
2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA. -
Fluorescent Dye
Sulfo-Cy5-N3 is a versatile fluorescent dye featuring an azide group that enables its use in click chemistry applications. Primarily utilized for imaging, this red fluorescent label (Excitation/Emission=642/670 nm) facilitates the visualization of biomolecules through the copper-catalyzed azide-alkyne cycloaddition (CuAAc) method when paired with alkyne-containing compounds. Additionally, it can participate in the ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it suitable for a variety of biological and chemical research applications.
