Catalog No.
Product Name
Application
Product Information
Citations
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Lymphocyte Tracker
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell-permeable fluorescent dye with an excitation wavelength of 492 nm and an emission wavelength of 517 nm. It covalently labels intracellular proteins, enabling the tracking of lymphocyte migration and proliferation in biological research. This reagent is particularly useful for studying immune responses and cellular dynamics in various experimental settings. -
Chemical
1,8-Diazafluoren-9-one is a chemical reagent primarily utilized in forensic analysis for the detection of latent fingerprints on porous surfaces. This compound reacts with amino acids found in fingerprints, resulting in the formation of highly fluorescent derivatives, with an excitation/emission maximum of approximately 470/570 nm. Its applications extend to enhancing imaging techniques in forensic science, facilitating reliable identification in criminal investigations. -
Calcium Indicator
Fluo-3 AM is a fluorescent calcium indicator that effectively chelates Ca2+ ions with high affinity. It is designed for the sensitive detection of intracellular calcium fluctuations, making it a valuable tool for monitoring cellular calcium dynamics. Due to its low cytotoxicity and efficient cellular uptake facilitated by the acetoxymethyl ester moiety, Fluo-3 AM is cleaved intracellularly, allowing for sustained binding to calcium ions and robust fluorescence output. This compound is widely used in studies related to signal transduction, muscle contraction, and various calcium-dependent cellular processes. -
Fat-soluble Diazo Dye
Sudan Black B is a fat-soluble diazo dye used primarily as a histochemical stain. This reagent effectively stains neutral triglycerides and lipids, making it a valuable tool in the identification and analysis of adipose tissues and lipid-containing structures in biological samples. Its applications extend to research in lipid metabolism, pathology, and histological studies. -
Cell Proliferation Assay Reagent
WST-1 is a water-soluble tetrazolium salt that serves as a reagent for cell proliferation assays. It selectively undergoes reduction by intracellular mitochondrial dehydrogenases, resulting in the production of a soluble formazan product detectable at 450 nm. This compound is utilized to assess cell viability and cytotoxicity, making it an essential tool in various biological and pharmacological research applications. -
Golgi-specific Fluorescent Dye
BODIPY FL C5-Ceramide is a Golgi-specific fluorescent dye that targets the Golgi apparatus for precise cellular visualization. This BODIPY-labeled ceramide derivative is synthesized in the endoplasmic reticulum and is effectively transported to the Golgi through ceramide transport proteins or vesicular mechanisms. With an excitation/emission wavelength of 505 nm/512 nm, it is suited for applications in cell biology and imaging studies, allowing researchers to observe and analyze cellular structures with enhanced clarity. -
Supravital Stain
Janus Green B is a supravital stain utilized for the visualization of live cells and tissues. This compound exhibits an oxygen-dependent staining reaction that can be reversibly inhibited by cyanide, making it a valuable tool in live-cell imaging. It has been effectively employed in the staining of peripheral nerves in insects, lymphatic vessels in rabbits, and mitochondria, aiding in various biological research applications related to cellular morphology and function. -
Fluorescent Dye
4-Di-1-ASP is a styryl dye that targets glioma cells for fluorescent imaging in live brain tissue. This reagent enables detailed analysis of cellular structures, viability, proliferation, and endocytic processes, including cytokinesis and phagocytosis. Additionally, 4-Di-1-ASP facilitates observations of mitochondrial architecture in living cells, exhibiting green fluorescence upon excitation (λex /λem = 475/606 nm). -
Fluorescent Probe
BODIPY-C12 is a boron-dipyrromethene derivative functioning as a fluorescent probe with an excitation wavelength of 490 nm. Its hydrophobic structure allows it to be highly sensitive to its surrounding environment, making it suitable for quantifying viscosity, critical micelle concentration, and critical micelle temperature. This compound serves as a valuable tool for researchers in assessing lipid environment dynamics and micelle formation in various biological studies. -
Fluorescent Dye
Calcein (mixture of isomers) is a calcium-dependent fluorescent dye that enables the visualization of calcium ions in biological systems. This reagent is commonly utilized in studies of bone metabolism and is effective for staining specific cellular regions in vitro. Additionally, Calcein can be employed in fluorometric assays and for the titration of calcium ions using EDTA, making it a versatile tool for various research applications. -
Fluorescent Dye
3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine fluorescent dye primarily used for the assessment of mitochondrial membrane potential. This dye exhibits significant fluorescence characteristics, making it an effective tool for studying mitochondrial dynamics and function in various cellular processes. It is widely utilized in research applications involving cell viability, apoptosis studies, and mitochondrial health assessments. -
pH Sensitive Fuorescent Probe
9-Amino-6-chloro-2-methoxyacridine is a pH-sensitive fluorescent probe that exhibits significant changes in fluorescence intensity in response to pH variations. This compound is particularly useful for monitoring vacuolar pH changes during substrate transport across the tonoplast via a proposed H+/solute antiport mechanism. Its application in cellular and molecular research facilitates the understanding of acid-base homeostasis in plant cells and other biological systems. -
Tumor Targeted Dye
MHI-148 is a near-infrared heptamethine cyanine dye that selectively targets tumors, making it ideal for cancer detection and diagnosis. This compound demonstrates preferential accumulation in the lysosomes and mitochondria of tumor cells, allowing for enhanced visualization. Its unique properties facilitate research applications in tumor biology and imaging studies, enabling more effective monitoring and understanding of cancer progression. -
Fluorescent Dye
2,3-Diaminonaphthalene is a selective fluorescent dye primarily used for the detection of selenium ions. It exhibits strong colorimetric and fluorometric properties, making it suitable for quantifying nitrite levels as well. This reagent finds applications in environmental monitoring and analytical chemistry, enabling sensitive detection and measurement of specific analytes in various research settings. -
Lipid Fluorescent Probe
NBD-PE is a lipid fluorescent probe that targets lipid bilayers, excelling in membrane and cell biology research. With an excitation wavelength of 465 nm and emission at 535 nm, this compound facilitates visualization of cellular membranes and lipid dynamics. Key applications include studying membrane structure, dynamics, and interactions in live cell imaging. -
Fluorescent Dye
BODIPY 500/510 C1, C12 is a fluorescent dye characterized by strong ultraviolet absorption and high quantum yield. It features a sharp fluorescence peak and remains stable across various physiological conditions, demonstrating minimal sensitivity to polarity and pH variations. This dye effectively penetrates cell membranes, allowing for the specific localization of neutral lipids within lipid droplets in both live and fixed cells. It is widely utilized for cellular imaging and lipid droplet labeling applications. Maximum excitation and emission wavelengths are 500 nm and 510 nm, respectively. Protect from light and store at -20°C. -
Fluorescent Membrane-staining Dye
Di-4-ANEPPDHQ is a polarity-sensitive membrane probe designed for visualizing membrane microdomains in living cells. This doubly charged fluorescent dye enables the assessment of lipid accumulation by producing a fluorescence spectrum shift in response to changes in the polarity of the lipid environment upon embedding within the cell membrane. With an excitation wavelength of 488 nm and emission wavelengths of 560 nm and 650 nm corresponding to liquid ordered and disordered phases, Di-4-ANEPPDHQ is ideal for fluorescence imaging studies focusing on membrane microstructure, lipid order, and membrane tension response. -
Amyloid-β Inhibitor
Hoechst 34580 tetrahydrochloride is a nuclear marker dye that selectively targets A/T-rich double-stranded DNA. This compound exhibits enhanced fluorescence intensity when bound to nucleic acids, making it valuable for live cell labeling applications. As the pH of the solution increases, the fluorescence intensity of Hoechst 34580 also increases, providing a reliable tool for studying cellular dynamics, DNA distribution, and nuclear morphology in real-time. This reagent is particularly useful in research focused on amyloid-β and related neurodegenerative processes. -
Fluorescent Probe
DAF-2DA (5,6-Diaminofluorescein diacetate) is a fluorescent probe designed for the selective detection of nitric oxide (NO) in biological samples. Upon reaction with NO, DAF-2DA is converted into a highly fluorescent compound, allowing for quantitative measurement of NO levels. This reagent is widely utilized in cellular and physiological studies to investigate NO signaling pathways and its role in various biological processes. -
H2O2 probe
Peroxy Orange 1 is a hydrogen peroxide (H2O2) specific probe designed for the detection of reactive oxygen species. It binds selectively to highly reactive oxygen species, enabling the visualization of H2O2 in live cells through green fluorescence. This compound is valuable for studying oxidative stress, cellular signaling, and related biological processes in various research applications. -
Cell Membrane Staining Agent
Octadecyl Rhodamine B chloride is a versatile amphiphilic fluorescent probe targeting cell membranes. This compound effectively stains cell membranes and is instrumental in membrane biology research. It exhibits fluorescence properties, with a maximum absorption and emission wavelength of 565 nm and 585 nm, respectively, when in Triton X-100. In aqueous solutions, the compound forms aggregates that shift absorption peaks to 524 nm and 574 nm, resulting in notable fluorescence quenching. -
Mitochondria Fluorescent Dye
MitoTracker Orange CMTMRos is a fluorescent dye that selectively labels mitochondria in live cells by exploiting the mitochondrial membrane potential (Ex/Em: 551/576 nm). This compound is essential for studying mitochondrial dynamics, morphology, and function. It is widely used in research applications, including cellular metabolism, apoptosis, and drug-response assays in various cell types. -
Zinc Ion Fluorophore
Zinquin ethyl ester is a zinc ion fluorophore specifically designed for the detection of intracellular zinc ions. This lipophilic probe readily penetrates cell membranes and exhibits a strong affinity for Zn2+, resulting in blue fluorescence upon binding. Primarily utilized in research applications focused on zinc signaling and cellular metal ion dynamics, Zinquin ethyl ester serves as a valuable tool for studying zinc-related biological processes. -
Lipophilic Fluorochrome
CellTracker CM-DiI is a lipophilic fluorochrome designed for the visualization and tracking of lymphocyte migration. This reagent enables the labeling of cells for detection in histological sections, with an excitation wavelength of 553 nm and an emission wavelength of 570 nm. Its application is critical in studies examining cellular dynamics and immune responses. -
Fluorogenic Ligand
DFHO is a fluorogenic ligand specifically designed for binding with the Corn fluorogenic aptamer. With a Kd value of 70 nM, DFHO undergoes a conformational change upon binding, resulting in enhanced fluorescence, thereby facilitating RNA imaging within cellular environments. This compound is valuable for researchers investigating RNA dynamics and localization in live cell assays. -
Mitochondrial ROS Indicator
MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red. Excitation/emission wavelength: 510/580 nm. -
Hydrophobic Fluorescent Stain
Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm. -
Fluorochrome
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis. -
Green Dye
BODIPY493/503 methyl bromide is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 493/503 nm. -
Neutral Lipid Dye
BODIPY 493/503 is a member of the BODIPY (boron-dipyrromethene) family of small-molecule fluorescent dyes, characterized by strong absorption in the ultraviolet-visible range, narrow and well-defined emission spectra, and high fluorescence quantum yields. These dyes exhibit minimal sensitivity to environmental polarity and pH, maintaining stable photophysical properties under a wide range of physiological conditions.
Due to the structural versatility of the BODIPY core, numerous derivatives with tailored properties can be generated. BODIPY-based lipid droplet probes readily permeate cellular membranes and selectively localize to neutral lipid compartments, enabling specific staining of intracellular lipid droplets. This makes them suitable for both live-cell imaging and fixed-cell applications.
Maximum excitation/emission wavelengths: 493/503 nm.
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Voltage-Sensitive Dye
Di-4-ANEPPS is a voltage-sensitive dye that targets voltage-gated ion channels, primarily inhibiting sodium currents. This compound alters fluorescence properties in response to changes in membrane potential, facilitating the examination of ion channel function. It is useful in cardiovascular research, particularly in studies involving electrophysiology of cardiomyocytes, myocardial ischemia, and investigating drug effects on cardiac cells. Di-4-ANEPPS is instrumental in assessing drug cardiotoxicity and elucidating the mechanisms underlying arrhythmias. -
Anti-microbial Agent/Kir3.2 Blocker
3,6-Diaminoacridine hemisulfate is an acridine compound that functions primarily as a broad-spectrum antimicrobial agent and a Kir3.2 potassium channel blocker. Its mechanism involves insertion into bacterial DNA, thereby disrupting replication and transcription, which ultimately leads to bacterial lysis. Additionally, this compound is utilized in research to investigate the neurological phenotype associated with Down syndrome. Due to its ability to penetrate the stratum corneum and accumulate in the cell nucleus, prolonged exposure warrants caution due to potential oncogenic effects. -
Fluorescent Tracer
Fluorescein is a fluorescent tracer commonly employed in medicinal and biological research, particularly for visualizing tumor-infected tissues. As a representative green fluorophore, it serves as a versatile scaffold for the development of various green fluorescent probes. Its high solubility and brightness make it an excellent choice for applications in microscopy and flow cytometry, facilitating studies in cellular and molecular biology. -
ROS Probe
HKOH-1 is a sensitive green fluorescent probe designed for the selective detection of hydroxyl radicals (·OH) in living cells, utilizing a maximum excitation wavelength of 500 nm and an emission wavelength of 520 nm. This reagent enables researchers to monitor oxidative stress and assess cellular responses to reactive oxygen species. Its application is critical in studies related to redox biology, neurodegenerative diseases, and cancer research. -
mtTrxR2 Probe
Mito-TRFS is an innovative off-on probe designed to selectively image mitochondrial thioredoxin reductase (TrxR2) in live cells. This reagent allows for the assessment of the redox status within mitochondria, facilitating the study of oxidative stress and mitochondrial function. Mito-TRFS is particularly valuable in research focusing on cellular responses to stress and the roles of TrxR2 in various disease models. -
Fluorescent Probe
DND-189 is a low-pH fluorescent probe that exhibits high sensitivity to neutral and acidic pH environments. This reagent is valuable for the quantification of pH levels within acidic organelles, enabling researchers to study intracellular pH dynamics in various biological contexts. Its unique properties make DND-189 an essential tool for applications in cellular imaging and pH monitoring. -
NO Fluorescent Detector
4,5-Diaminofluorescein is a sensitive fluorescent detector that specifically targets nitric oxide (NO). This reagent exhibits robust fluorescence upon reaction with NO, enabling the visualization and measurement of NO levels in cells and tissues. It is widely used in research applications related to nitric oxide signaling, endothelial function, and various physiological processes. -
Fluorescent Dye
ER Tracker Yellow is a temperature-sensitive fluorescent dye specifically designed to target the endoplasmic reticulum (ER). This probe exhibits exceptional temperature sensitivity of 3.9% per °C, with stable performance unaffected by pH or Ca2+ concentrations. It is ideal for real-time monitoring of local temperature changes in the ER, maintaining functionality in fixed cells. ER Tracker Yellow is compatible with a wide variety of cell lines and primary cells, including HeLa and MEF cells, making it a versatile tool for cellular research applications. -
Fluorescent Dye
Thiazole orange dimer YOYO 1 is a fluorescent dye that specifically targets DNA for staining applications. As a tetracationic homodimer of oxazole yellow, it exhibits minimal fluorescence in solution but significantly enhances its emission upon binding to double-stranded DNA via diintercalation, resulting in a fluorescence intensity increase of over 3200-fold. This remarkable amplification of fluorescence makes YOYO 1 an invaluable tool for various research applications, including nucleic acid quantification and visualization in molecular biology and genetic studies. -
Red Fluorophore
DFAME is a red fluorophore with excitation and emission wavelengths of 508 nm and 641 nm, respectively. It selectively binds to dimeric fluorescent RNA aptamers derived from Beetroot and Corn, yielding complexes with dissociation constants of 460 nM and 3600 nM, respectively. These Beetroot-DFAME and Corn-DFAME complexes facilitate the assembly of RNA structures within living cells, making them valuable tools for studying RNA nanostructures. The application of DNA/RNA nanostructures holds significant promise in advancing research in cell and gene therapy. -
Chemiluminescent Compound
Luminol sodium salt is a chemiluminescent compound that produces light at a maximum wavelength of 425 nm. This compound is widely utilized in forensic science as a sensitive indicator for the presence of blood stains, leveraging its unique ability to emit light in the presence of hemoglobin. Additionally, Luminol sodium salt has applications in environmental monitoring and biochemical assays, enhancing detection and analysis in various research fields. -
Fluorescent Dye
S0456 is a fluorescent dye precursor that facilitates the synthesis of the folate receptor-targeted near-infrared dye OTL 38. It enhances OTL 38 by imparting excellent optical properties along with high affinity and specificity for folate receptors. This compound is valuable in the research of tumor optical imaging agents, aiding in the development of advanced imaging techniques for cancer diagnostics. -
Quencher
Dabcyl acid is a nonfluorescent chromophore used primarily as a quencher in molecular fluorescent assays. It is effective in molecular beacon applications for the detection and reporting of specific nucleic acids in homogeneous solutions. Dabcyl acid enhances the sensitivity and specificity of nucleic acid probes, making it a valuable tool in genetic research and diagnostics. -
LDs/Mitochondria Dye
BETA-1 is a twisted intramolecular charge transfer (TICT) aggregation-induced emission (AIE) dye that targets lipid droplets (LDs) and mitochondria. It exhibits cyan fluorescence in LDs and red fluorescence in mitochondria, facilitating simultaneous dual-color imaging. BETA-1 is suitable for both in vivo and in vitro studies, making it an essential tool for researchers investigating cellular lipid metabolism and mitochondrial function. -
Hypochlorous Acid Detector
HKOCl-3 is a selective fluorescent probe designed for the detection of hypochlorous acid. This reagent exhibits high sensitivity with an excitation wavelength of 490 nm and an emission wavelength of 527 nm. HKOCl-3 is suitable for various biological research applications involving oxidative stress, inflammation studies, and the monitoring of hypochlorous acid levels in biological samples. -
Lipophilic Fluorescent Probe
5-Dodecanoylaminofluorescein is a lipophilic fluorescent probe that serves as a free fatty acid conjugate of fluorescein. This compound is instrumental in studies of membrane fluidity and the determination of critical micelle concentrations of detergents. Additionally, it can be utilized in the synthesis of hydrophobic nanospheres, enhancing applications in drug delivery systems. -
Fluorescent Calcium Indicator
Calcium Green 1AM is a cell-permeant fluorescent calcium indicator that targets calcium ions within cells. Upon cellular uptake, it is converted by intracellular esterases into its active form, facilitating precise measurement of calcium fluctuations. This reagent is widely utilized in cell physiology studies, calcium signaling research, and live-cell imaging applications. -
Fluorescent Dye
Acridine Orange base is a cell-permeable fluorescent dye primarily utilized for staining nucleic acids in various organisms, including bacteria, parasites, and viruses. This dye exhibits distinct fluorescence characteristics; it emits green light when bound to double-stranded DNA (Ex=488 nm, Em=520-524 nm) and red light when associated with single-stranded DNA or RNA (Ex=457 nm, Em=630-644 nm). Acridine Orange base is particularly valuable in fluorescence microscopy for distinguishing human cells under acidic conditions (pH=3.5) and is widely employed in cell cycle assays. -
Fluorescent Indicator
SBFI-AM is a sodium-selective fluorescent indicator designed for monitoring Na+ concentrations in biological systems. With a Kd of 6.7 mM for Na+ and 166 mM for K+, SBFI-AM demonstrates high selectivity for sodium ions. Its excitation and emission wavelengths are 340/380 nm and 500 nm, respectively. This reagent is widely used in cellular imaging and physiological studies to investigate sodium signaling and ion homeostasis. -
Lysosome-Specific Fluorescent Dye
Green DND-26 is a lysosome-specific fluorescent dye that exhibits a maximum excitation/emission wavelength of 504/511 nm. Comprising a fluorescein moiety linked to weak bases, this compound effectively penetrates cell membranes and accumulates in lysosomal structures. It is ideal for studying lysosomal biosynthesis and related pathological processes, facilitating the observation of cellular dynamics associated with lysosomal function.
