Fludarabine Phosphate (Fludara)

Catalog No.: A10395

Fludarabine Phosphate (Fludara) Chemical Structure

CAS NO. 75607-67-9

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.

Availability: In stock

Package Price Qty
10 mg
$40.00
50 mg
$120.00
100 mg
$150.00
10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Targets
DNA polymerase α DNA polymerase δ
1.1 μM(Ki )1.3 μM(Ki)
In vitro (25°C) DMSO 73 mg/mL (199.88 mM)
Water 2 mg/mL heating (5.47 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.38 mL 136.91 mL 273.82 mL
0.5 mM 5.48 mL 27.38 mL 54.76 mL
1 mM 2.74 mL 13.69 mL 27.38 mL
5 mM 0.55 mL 2.74 mL 5.48 mL

*The above data is based on the productmolecular weight 365.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10395
Actions No
M. Wt 365.2
Formula C10H13FN5O7P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 75607-67-9
Synonyms N/A
SMILES O[[email protected]]1[[email protected]](O)[[email protected]](O[[email protected]]1n1cnc2c1nc(F)nc2N)COP(=O)(O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Fludarabine Phosphate (Fludara) | Fludarabine Phosphate (Fludara) Supplier | purchase Fludarabine Phosphate (Fludara) | Fludarabine Phosphate (Fludara) cost | Fludarabine Phosphate (Fludara) manufacturer | order Fludarabine Phosphate (Fludara) | Fludarabine Phosphate (Fludara) distributor | buy 75607-67-9| 75607-67-9 Supplier | purchase 75607-67-9 | 75607-67-9 cost | 75607-67-9 manufacturer | order 75607-67-9 | 75607-67-9 distributor
Rewards