Fludarabine Phosphate (Fludara)

Catalog No.: A10395

Fludarabine Phosphate (Fludara)

Fludarabine Phosphate (Fludara) Chemical Structure

CAS NO. 75607-67-9

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $40.00

Special Price $32.00

50 mg

Regular Price: $120.00

Special Price $96.00

100 mg

Regular Price: $150.00

Special Price $120.00

10mM * 1mL in DMSO

Regular Price: $60.00

Special Price $48.00

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Targets
DNA polymerase α DNA polymerase δ
1.1 μM(Ki )1.3 μM(Ki)
In vitro (25°C) DMSO 66 mg/mL (180.71 mM)
Water Warmed: 2 mg/mL (5.47 mM)
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.38 mL 136.91 mL 273.82 mL
0.5 mM 5.48 mL 27.38 mL 54.76 mL
1 mM 2.74 mL 13.69 mL 27.38 mL
5 mM 0.55 mL 2.74 mL 5.48 mL

*The above data is based on the productmolecular weight 365.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10395
CAS No. 75607-67-9
Formula C10H13FN5O7P
M. Wt 365.2
Purity >98%
SMILES O[[email protected]]1[[email protected]](O)[[email protected]](O[[email protected]]1n1cnc2c1nc(F)nc2N)COP(=O)(O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Fludarabine Phosphate (Fludara) | Fludarabine Phosphate (Fludara) Supplier | purchase | cost | manufacturer | order | distributor | buy 75607-67-9| 75607-67-9 Supplier | purchase 75607-67-9 | 75607-67-9 cost | 75607-67-9 manufacturer | order 75607-67-9 | 75607-67-9 distributor
Rewards