Gefitinib hydrochloride

Catalog No.: A15093

EGFR Inhibitor

Gefitinib hydrochloride

Gefitinib hydrochloride Chemical Structure

CAS NO. 184475-55-6

Gefitinib hydrochloride is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR.

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500 mg
$45.00
1000 mg
$75.00
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Biological Activity

Gefitinib hydrochloride is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR.
In vitro DMSO 7 mg/mL (14.48 mM)
Water 1 mg/mL (2.06 mM)
Ethanol 1 mg/mL (2.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.69 mL 103.44 mL 206.89 mL
0.5 mM 4.14 mL 20.69 mL 41.38 mL
1 mM 2.07 mL 10.34 mL 20.69 mL
5 mM 0.41 mL 2.07 mL 4.14 mL

*The above data is based on the productmolecular weight 483.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15093
Actions Inhibitor
CAS No. 184475-55-6
Formula C22H25Cl2FN4O3
M. Wt 483.36
Solubility DMSO
Purity >98%
Synonyms Iressa hydrochloride, ZD 1839 hydrochloride, ZD-1839 hydrochloride, ZD1839 hydrochloride
SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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