Gefitinib (Iressa)

Gefitinib is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.
Grouped product items
Product Name Price Stock Qty
Gefitinib (Iressa) 100mg
$40.00
In stock
Gefitinib (Iressa) 250mg
$50.00
In stock
Gefitinib (Iressa) 500mg
$60.00
In stock
Gefitinib (Iressa) 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's Gefitinib (Iressa) has been cited by 2 publications
  • Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259
  • Mansi Srivastava, .et al. , Int Immunopharmacol, 2019, 71: 188-197 PMID: 30909134
  • Biological Activity
    Discription Gefitinib is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.
    Targets
    Target Value
    Product Information
    Catalog Num A10422
    Formula C22H24ClFN4O3
    Molecular Weight 446.9
    CAS Number 184475-35-2
    SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
    Synonyms ZD-1839
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 80 mg/mL (179 mM)
    Water Insoluble
    Ethanol 4 mg/mL (8.95 mM)
    In vivo 1% CMC Na 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.38 mL 111.88 mL 223.76 mL
    0.5 mM 4.48 mL 22.38 mL 44.75 mL
    1 mM 2.24 mL 11.19 mL 22.38 mL
    5 mM 0.45 mL 2.24 mL 4.48 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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