MC-Sq-Cit-PAB-Gefitinib

Catalog No.: A18521

MC-Sq-Cit-PAB-Gefitinib

MC-Sq-Cit-PAB-Gefitinib Chemical Structure

CAS NO. 1941168-63-3

MC-Sq-Cit-PAB-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

MC-Sq-Cit-PAB-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.99 mL 49.97 mL 99.95 mL
0.5 mM 2 mL 9.99 mL 19.99 mL
1 mM 1 mL 5 mL 9.99 mL
5 mM 0.2 mL 1 mL 2 mL

*The above data is based on the productmolecular weight 1000.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18521
CAS No. 1941168-63-3
Formula C50H61ClFN10O9
M. Wt 1000.53
Purity >98%
SMILES COC1=CC2=[N+](CC3=CC=C(NC([[email protected]@H](NC(C4(C(NCCCCCN5C(C=CC5=O)=O)=O)CCC4)=O)CCCNC(N)=O)=O)C=C3)C=NC(NC6=CC=C(F)C(Cl)=C6)=C2C=C1OCCCN7CCOCC7
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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