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Biological Activity
MC-Sq-Cit-PAB-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.99 mL | 49.97 mL | 99.95 mL |
| 0.5 mM | 2 mL | 9.99 mL | 19.99 mL |
| 1 mM | 1 mL | 5 mL | 9.99 mL |
| 5 mM | 0.2 mL | 1 mL | 2 mL |
*The above data is based on the productmolecular weight 1000.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18521 |
|---|---|
| CAS No. | 1941168-63-3 |
| Formula | C50H61ClFN10O9 |
| M. Wt | 1000.53 |
| Purity | >98% |
| SMILES | COC1=CC2=[N+](CC3=CC=C(NC([C@@H](NC(C4(C(NCCCCCN5C(C=CC5=O)=O)=O)CCC4)=O)CCCNC(N)=O)=O)C=C3)C=NC(NC6=CC=C(F)C(Cl)=C6)=C2C=C1OCCCN7CCOCC7 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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