Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
N4-Acetylsulfamethoxazole-d4 is a deuterium-labeled derivative of N4-Acetylsulfamethoxazole. This compound serves as a stable isotope used in pharmacokinetic studies and metabolic research related to sulfamethoxazole, a sulfonamide antibiotic known for its bacteriostatic properties. Its application in isotopic tracing facilitates the analysis of drug metabolism and bioavailability, making it valuable in pharmacological investigations and related fields. -
Stable Isotope
Mandelic Acid-13C8 is a stable isotope-labeled variant of the alpha-hydroxycarboxylic acid, mandelic acid, featuring eight carbon-13 atoms. It serves as a key intermediate for pharmaceutical applications and the synthesis of fine chemicals. Mandelic acid possesses notable antimicrobial properties, making it relevant in the study of urinary tract infections and vaginal trichomoniasis. Additionally, it demonstrates significant sperm-immobilizing activity with minimal vaginal irritation, supporting its use in reproductive health research. -
Stable Isotope
Monooctyl phthalate-d4 is a deuterium-labeled derivative of Monooctyl phthalate, serving as a stable isotope for analytical applications. This compound exhibits antimycobacterial activity, with a minimum inhibitory concentration (MIC) of 20 μg/mL. It is primarily used in research focusing on the study of mycobacterial infections and their treatment. -
Stable Isotope
4-Hydroxybenzoic acid-13C is a stable isotope-labeled derivative of 4-Hydroxybenzoic acid, a phenolic compound closely related to benzoic acid. It exhibits antibacterial activity, effectively inhibiting a range of gram-positive and select gram-negative bacteria with an IC50 of 160 μg/mL. This reagent is valuable for applications in metabolic studies, isotopic tracing, and antimicrobial research, providing insights into bacterial response and compound bioavailability. -
Stable Isotope
Ethyl acetoacetate-d5 is a stable isotope-labeled variant of ethyl acetoacetate, an ester commonly employed as an intermediate in the synthesis of diverse chemical compounds. This reagent demonstrates significant biological activity as an inhibitor of bacterial biofilm formation, making it valuable for studies related to microbial growth and biofilm development. Researchers utilize ethyl acetoacetate-d5 in metabolic tracing and kinetic studies, leveraging its isotopic labeling for enhanced analytical applications in synthetic and biological research. -
Stable Isotope
Tenuazonic acid-d13 is a deuterium-labeled derivative of Tenuazonic acid, a nonhost-selective mycotoxin from the tetramic acid family. This compound primarily functions as a protein biosynthesis inhibitor by interfering with ribosomal activity, thus suppressing protein release. Tenuazonic acid-d13 exhibits significant biological activities, including photosystem II inhibition via the D1 protein, and demonstrates antiviral effects against various viruses such as measles and respiratory viruses. Furthermore, this reagent is utilized in research exploring the compound’s potential inhibitory effects on skin cancer. -
Stable Isotope
Probenecid-d14 is a deuterated form of Probenecid, which serves as a selective agonist of the transient receptor potential vanilloid 2 (TRPV2) channels. This stable isotope enables precise tracking and quantification in metabolic studies. Additionally, Probenecid-d14 is recognized for its inhibitory effects on pannexin 1 channels, making it a valuable tool for investigating cellular signaling pathways and receptor interactions in various biological research applications. -
Stable Isotope
Syringic acid-d6 is a deuterated form of syringic acid, serving as a stable isotope for analytical applications. This compound exhibits significant antioxidant properties and has been shown to inhibit the oxidation of low-density lipoproteins (LDL). It is useful in biochemical research for studying the metabolic pathways of antioxidants and their potential protective effects in cardiovascular health. -
Isotope-Labeled Compound
Isothipendyl-d6 is a deuterium-labeled compound utilized in various chemical research applications. This isotope-labeled version of (7E,9E)-β-Ionylideneacetaldehyde serves as a valuable tool for studying metabolic pathways and reaction mechanisms. Its unique isotopic properties facilitate enhanced analytical detection and quantification in mass spectrometry and nuclear magnetic resonance (NMR) experiments, making it essential for researchers focusing on organic synthesis and molecular interactions. -
Stable Isotope
Oxyphenbutazone-d9 is a deuterated derivative of Oxyphenbutazone, a non-selective cyclooxygenase (COX) inhibitor. This compound exhibits notable anti-inflammatory properties and serves as a key metabolite of Phenylbutazone. In addition to its COX inhibition, Oxyphenbutazone has been shown to selectively target and eliminate non-replicating Mycobacterium tuberculosis, making it valuable in tuberculosis research and anti-infective studies. -
Stable Isotope
(R)-Propranolol-d7 is a deuterated derivative of (R)-Propranolol, serving as a stable isotope-labeled compound. This reagent is invaluable for pharmacokinetic studies and metabolic pathway analysis, enabling the tracking of drug metabolism and distribution in biological systems. Researchers can utilize (R)-Propranolol-d7 in studies focused on cardiovascular research, anxiety treatments, and the mechanisms of action associated with beta-adrenergic receptors. -
Stable Isotope
Hydroxymetronidazole-d4 is a deuterium-labeled derivative of Hydroxymetronidazole, a nitroimidazole metabolite of Metronidazole. This stable isotope serves as a valuable tool in pharmacokinetic studies and metabolic pathway investigations. It is applicable in research related to bacterial and protozoal infections, particularly in poultry, as well as in the study of swine dysentery and genital trichomoniasis in cattle. -
Stable Isotope
Tinidazole-d5 is a deuterium-labeled analog of Tinidazole, a 5-nitroimidazole antibiotic. This stable isotope compound is primarily utilized in pharmacokinetic studies and metabolic research. Tinidazole exhibits selective antibacterial activity against anaerobic bacteria and protozoa, making it valuable for investigations into infectious diseases and microbiome interactions. -
Stable Isotope
Chloroxylenol-d6 is a deuterium-labeled form of chloroxylenol, a broad-spectrum antimicrobial agent. This compound exerts activity against bacteria, algae, fungi, and viruses, making it valuable in various microbiological applications. Chloroxylenol-d6 is particularly useful for research involving stable isotope methods, allowing for enhanced analytical studies in pharmacology and environmental science. -
Stable Isotope
Brodimoprim-d6 is a deuterium-labeled derivative of Brodimoprim, a potent dihydrofolate reductase inhibitor. This compound exhibits strong antimicrobial activity against a wide range of both gram-negative and gram-positive bacteria, making it a valuable tool in microbiological research. The stable isotope labeling allows for enhanced tracking and analysis in pharmacokinetic studies and metabolic profiling. -
Stable Isotope
Ethylenediaminetetraacetic acid-13C4 (EDTA-13C4) is a stable isotope-labeled form of Ethylenediaminetetraacetic acid (EDTA), a potent metal chelating agent that binds to bivalent and trivalent metal cations, particularly calcium. EDTA exhibits a range of biological activities, including antibacterial, anti-inflammatory, antioxidant, and anticoagulant properties. It plays a critical role in mitigating metal ion-catalyzed oxidative damage to proteins and maintaining a reducing environment during protein purification processes. EDTA has potential therapeutic applications in liver fibrosis and is also relevant for research involving coronary artery disease and neurological disorders. -
Stable Isotope
Pentyl 4-hydroxybenzoate-d11 is a deuterated analog of Pentyl 4-hydroxybenzoate, which serves as a stable isotope used in various research applications. This compound exhibits antibacterial properties and has been shown to inhibit induced oxygen consumption, making it relevant in studies investigating metabolic processes and preservative efficacy. Its isotopic labeling enhances tracking and quantification in biochemical assays and environmental studies. -
Stable Isotope
Lauric acid-d5 is a stable isotope-labeled derivative of lauric acid, a medium-chain fatty acid known for its potent bactericidal activity. This compound has demonstrated effective antimicrobial properties, with EC50 values against Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis measured at 2, 6, and 4 µg/mL, respectively. Lauric acid-d5 is applicable in research focused on lipid metabolism, antimicrobial studies, and metabolic tracing in biological systems. -
Stable Isotope
Sulfanitran-13C6 is a stable isotope-labeled form of the antibacterial and anticoccidial agent Sulfanitran. This compound functions as a stimulator of the multidrug resistance protein 2 (MRP2), enhancing its affinity for estradiol-17-β-D-glucuronide (E217βG). Sulfanitran-13C6 is useful for research applications such as studying drug transport and metabolism, particularly in the context of poultry health and pharmacology. -
Stable Isotope
3-Pentanol-d5 is a deuterium-labeled variant of 3-Pentanol, a volatile organic compound with significant biological relevance. This stable isotope serves as a tool for tracing studies in organic synthesis and metabolic research. 3-Pentanol is known to induce plant immune responses against microbial pathogens and insect pests, making it valuable for studies on plant defense mechanisms and insect behavior in agricultural contexts. -
Stable Isotope
Rabeprazole sulfide-d3 is a deuterium-labeled analog of Rabeprazole Sulfide, which serves as a metabolite of the proton pump inhibitor Rabeprazole. This compound effectively inhibits the motility of Helicobacter pylori, making it a valuable tool for studying H. pylori infections. Rabeprazole sulfide-d3 can facilitate research on antibiotic resistance and the mechanisms underlying H. pylori pathogenesis. -
Stable Isotope
16β-Hydroxy-17β-estradiol-2,4-d2 is a stable isotope-labeled derivative of 16β-Hydroxy-17β-estradiol, providing a crucial tool for metabolic studies. This compound retains the biological activity of its non-labeled counterpart while enabling more precise quantification in biological assays. It is particularly useful in pharmacokinetic studies and isotopic labeling experiments, facilitating a deeper understanding of estrogen metabolism and signaling pathways. -
Stable Isotope
3,4,5-Trimethoxybenzoic acid-d3, a deuterated form of 3,4,5-Trimethoxybenzoic acid, acts as a stable isotope for various analytical applications. This benzoic acid derivative serves as a critical building block in medicinal chemistry and organic synthesis. It has demonstrated antibacterial activity against Staphylococcus aureus, with a minimum inhibitory concentration of 0.97 μg/mL, making it useful for microbial studies and drug development research. -
Stable Isotope
Veratraldehyde-13C (3,4-Dimethoxy[7-13C]-benzaldehyde) is a stable isotope-labeled derivative of Veratraldehyde, targeting the PilY1 protein. This compound exhibits significant antibacterial activity against Pseudomonas aeruginosa and demonstrates a repellent effect against mosquitoes and ticks. Veratraldehyde-13C is useful in research applications involving metabolic studies, flavoring agent assessments, and investigations into the interactions of aromatic compounds with biological targets. -
Stable Isotope
Ronidazole-d3 is a deuterium-labeled derivative of Ronidazole, primarily functioning as a stable isotope for analytical applications. This compound exhibits potent antiprotozoal and antimicrobial properties, and is particularly effective against Tritrichomonas foetus in feline models. Ronidazole-d3 is suitable for research related to histomoniasis and swine dysentery, facilitating studies on these significant veterinary diseases. -
Stable Isotope
Methyl paraben-d4 is the deuterium-labeled form of Methyl Paraben, a well-characterized chemical allergen derived from Tsuga dumosa. As a stable, non-volatile compound, it functions as an antimicrobial preservative in food, pharmaceuticals, and cosmetics. Methyl paraben has been shown to increase histamine release, potentially influencing cell-mediated immunity, making it valuable for research applications in allergenicity and immunological studies. -
Stable Isotope
Saccharin-13C6 is a stable isotope-labeled variant of saccharin, a non-caloric artificial sweetener. It exhibits bacteriostatic properties and can modulate microbiome activities, making it valuable in metabolic and nutritional research. The use of Saccharin-13C6 in studies allows for precise tracking of metabolic pathways and interactions with gut microbiota, contributing to a deeper understanding of its biological effects. -
Stable Isotope
trans-Cinnamic acid-d5 is a deuterium-labeled derivative of trans-Cinnamic acid, a naturally occurring compound known for its antimicrobial properties. This stable isotope can be utilized in various research applications, including pharmacokinetic studies and metabolic profiling. It exhibits a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen Aeromonas sobria, SY-AS1, making it a valuable reagent for studies related to antimicrobial efficacy and resistance. -
Stable Isotope
1-Tetradecanol-d2 is a deuterium-labeled variant of 1-Tetradecanol, a straight-chain saturated fatty alcohol derived from Myristica fragrans. This compound exhibits notable antibacterial and anti-inflammatory properties, specifically in the context of periodontitis. It serves as a valuable stable isotope in research applications involving metabolic studies, lipid metabolism, and the investigation of fatty alcohols’ roles in biological systems. -
Stable Isotope
Valacyclovir-d4 hydrochloride is a deuterated form of the antiviral agent Valacyclovir hydrochloride, designed for use as a stable isotope in research applications. It effectively inhibits herpes simplex virus type 1 (HSV-1) with a half-maximal inhibitory concentration (IC50) of 2.9 μg/ml. This compound serves as a prodrug to Acyclovir, allowing for effective studies on antiviral mechanisms and pharmacokinetics in virology and medicinal chemistry research. -
Stable Isotope
Trimethoprim-13C3 is a stable isotope-labeled variant of Trimethoprim, a potent bacteriostatic antibiotic that acts primarily as a dihydrofolate reductase inhibitor. This compound exhibits significant activity against a variety of Gram-positive and Gram-negative aerobic bacteria and is employed in research focused on conditions such as urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim has been shown to inhibit Influenza A virus infection in chick embryos when used in conjunction with zinc, making it a valuable tool for studies related to antimicrobial and antiviral therapies. -
Stable Isotope
Iclaprim-d6 is a deuterium-labeled derivative of Iclaprim, a selective inhibitor of bacterial dihydrofolate reductase. This compound effectively inhibits the growth of methicillin-resistant Staphylococcus aureus (MRSA) with a minimal inhibitory concentration (MIC90) of 0.06 μg/mL. Iclaprim-d6 serves as a valuable tool for research applications involving antibiotic resistance and the mechanisms of bacterial growth inhibition. -
Stable Isotope
Tedizolid-13C,d3 is a stable isotope-labeled form of Tedizolid, which is an oxazolidinone antibiotic. Its primary mechanism involves the inhibition of bacterial protein synthesis by binding to the 23S ribosomal RNA component of the 50S ribosomal subunit. This compound is essential for research applications in studying antibiotic resistance, ribosomal function, and the pharmacokinetics of Tedizolid in various biological systems. -
Stable Isotope
Erythromycin-d6 is a deuterium-labeled analog of Erythromycin, a macrolide antibiotic derived from the actinomycete Streptomyces erythreus. This compound exhibits broad-spectrum antimicrobial activity by binding to the 50S ribosomal subunit of bacteria, thereby inhibiting RNA-dependent protein synthesis through the blockade of transpeptidation and translocation processes. Erythromycin-d6 is valuable for research applications in pharmacokinetics and metabolic studies, particularly in tracing and quantifying the pharmacological behavior of Erythromycin in various biological systems. -
Stable Isotope
Cefazolin-13C2,15N sodium is a stable isotope-labeled derivative of the first-generation cephalosporin antibiotic, Cefazolin. This reagent is designed for advanced research in bacterial infections, leveraging its antimicrobial properties. Additionally, Cefazolin has demonstrated anti-inflammatory effects, making it valuable for studies related to postoperative cognitive dysfunction (POCD) and other inflammatory conditions. -
Stable Isotope
Orbifloxacin-d4 is a deuterated derivative of Orbifloxacin, functioning as a stable isotope tracer in biological research. This compound is utilized for pharmacokinetic studies and metabolic tracing, providing insights into drug metabolism and pharmacodynamics. Its isotopic labeling allows for enhanced detection and quantification in various analytical assays. -
Stable Isotope
Gatifloxacin-d4 is a deuterium-labeled derivative of the fluoroquinolone antibiotic Gatifloxacin, which primarily targets bacterial topoisomerases II. It exhibits broad-spectrum antibacterial activity, with IC50 values of 13.8 μg/mL against S. aureus topoisomerase IV and 0.109 μg/mL for E. coli DNA gyrase. This stable isotope-labeled compound is suitable for investigative research into bacterial infections, particularly in studies related to bacterial conjunctivitis. -
Stable Isotope
trans-Cinnamic acid-d7 is a deuterium-labeled derivative of trans-Cinnamic acid, enabling enhanced tracking in metabolic studies. This compound exhibits natural antimicrobial properties, demonstrating a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen Aeromonas sobria, strain SY-AS1. It is primarily utilized in biochemical research to study metabolic pathways and antimicrobial efficacy. -
Stable?Isotope
Lactate-d3 sodium (60% w/w in water) is a stable isotope of lactic acid sodium that acts as a hydroxycarboxylic acid receptor 1 (HCAR1) activator and serves as an epigenetic modulator through the lactylation of lysine residues. This compound is a key end-product of glycolysis, linking metabolic processes such as glycolysis and oxidative phosphorylation. Additionally, it plays a significant role in tumor metabolism and has been implicated in enhancing anti-tumor immunity. Lactate-d3 sodium also exhibits antimicrobial properties, making it suitable for use in food preservation. -
Stable Isotope
Lauric acid-d23 is a deuterium-labeled derivative of lauric acid, a medium-chain fatty acid known for its potent bactericidal properties. This compound exhibits strong antimicrobial activity, with effective concentration (EC50) values of 2 μg/mL against Propionibacterium acnes, 6 μg/mL against Staphylococcus aureus, and 4 μg/mL against Staphylococcus epidermidis. Lauric acid-d23 is valuable for use in biochemical research, particularly in studies exploring lipid metabolism and the antimicrobial mechanisms of fatty acids. -
Stable Isotope
Nonanoic acid-d17 is a deuterium-labeled derivative of nonanoic acid, a naturally occurring saturated fatty acid with nine carbon atoms. This compound serves as a stable isotope and is utilized in metabolic studies and tracer experiments. Nonanoic acid exhibits significant antibacterial activity, reduces bacterial translocation, and enhances the secretion of porcine β-defensins 1 (pBD-1) and pBD-2, making it valuable for research in antimicrobial mechanisms and gut health. -
Stable Isotope
Hexadecane-d34 is a deuterium-labeled stable isotope of hexadecane, a saturated hydrocarbon belonging to the alkane family. This compound serves as a valuable organic solvent and is a key component of petroleum. Hexadecane-d34 is primarily used in research applications focused on understanding the bacterial degradation of hydrophobic compounds, making it an important tool in environmental and biochemical studies. -
Stable Isotope
Lauric acid-d3 is a deuterium-labeled derivative of lauric acid, a medium-chain fatty acid noted for its potent bactericidal activity. It exhibits effective antimicrobial properties, with EC50 values of 2 μg/mL for Propionibacterium acnes, 6 μg/mL for Staphylococcus aureus, and 4 μg/mL for Staphylococcus epidermidis. Lauric acid-d3 is primarily utilized in tracer studies and metabolic research to investigate fatty acid metabolism and functions in various biochemical pathways. -
Stable?Isotope
Lactate-d4 sodium (60% w/w in water) is a deuterium-labeled derivative of lactic acid, targeting hydroxycarboxylic acid receptor 1 (HCAR1) for its biological activity. This compound serves as an epigenetic modulator, promoting lactylation of lysine residues and functioning as an important glycolytic end-product linking glycolysis and oxidative phosphorylation. As an oncometabolite, lactate-d4 sodium has demonstrated roles in anti-tumor immunity while also exhibiting antimicrobial properties that may be applied in food preservation. Its stable isotope labeling makes it a valuable tool for metabolic studies and tracer experiments. -
Stable Isotope
Lauric acid-13C is a stable isotope-labeled version of lauric acid, a medium-chain fatty acid recognized for its potent bactericidal activity. Its effectiveness is demonstrated by EC50 values of 2 μg/mL against Propionibacterium acnes, 6 μg/mL against Staphylococcus aureus, and 4 μg/mL against Staphylococcus epidermidis. This reagent is useful for metabolic tracing studies and examining fatty acid metabolism in various biological contexts. -
Stable Isotope
4-Hydroxybenzoic acid-d4 is a deuterium-labeled analog of 4-Hydroxybenzoic acid, a phenolic compound that serves as a potent antimicrobial agent. This compound demonstrates inhibitory activity against a variety of gram-positive bacteria as well as certain gram-negative strains, exhibiting an IC50 value of 160 μg/mL. It is primarily utilized in metabolic studies and as a stable isotope for biochemical applications. -
Stable Isotope
Omadacycline-d9 is a deuterium-labeled derivative of Omadacycline, designed for use as a stable isotope internal standard in analytical applications. This compound serves as a valuable tool for quantifying Omadacycline levels in biological samples, facilitating accurate pharmacokinetic studies and metabolic profiling. Researchers can leverage Omadacycline-d9 to enhance the reliability of their assays in drug development and therapeutic monitoring. -
Stable Isotope
Maleic acid-d2 is a deuterium-labeled derivative of maleic acid, which serves as a stable isotope for research applications. It functions primarily as an inhibitor of glutamate decarboxylase (GAD) in organisms such as E. coli and L. monocytogenes, making it useful for studies related to neurotransmitter regulation and bacterial metabolism. This compound is valuable in the fields of metabolic research and biochemical assays. -
Stable Isotope
L-Lactic acid-13C-1 sodium serves as a stable isotope-labeled precursor for various biochemical applications, including the study of metabolic pathways and biopolymer synthesis. This compound demonstrates key biological activity by exhibiting antiproliferative effects, making it valuable for research involving cancer metabolism and tissue engineering. Additionally, L-Lactic acid-13C-1 sodium is essential for the production of the biodegradable polymer poly-lactic acid, contributing to advancements in sustainable materials research. -
Stable Isotope
Vitamin D3-d3 is a deuterium-labeled form of Vitamin D3 (Cholecalciferol), a naturally occurring vitamin essential for various biological functions. This stable isotope is utilized in metabolic studies and tracer experiments to investigate Vitamin D3 metabolism, mechanisms of action, and its role in cellular differentiation and inhibition of cancer cell proliferation. Its applications extend to research in endocrinology, oncology, and nutrition.
