Catalog No.
Product Name
Application
Product Information
Citations
-
Stable Isotope
(±)-Leucine-d10 is a deuterium-labeled form of (±)-Leucine, which serves as a stable isotope. This compound exhibits significant growth inhibition of Escherichia coli HfrH by 92.08%, making it a valuable tool for studying metabolic pathways and protein synthesis. Its applications extend to various fields including biochemical research, nutrition studies, and chemosterilization processes. -
Stable Isotope
DL-3-Phenyllactic acid-d3 is a deuterated derivative of DL-3-Phenyllactic acid, functioning as a stable isotope. This compound exhibits broad-spectrum antimicrobial activity, making it valuable for research in microbiology and pharmacology. Its unique isotopic labeling enables precise tracking and quantification in metabolic studies and helps elucidate biochemical pathways involving phenyl lactate metabolism. -
Stable Isotope
D-Glucose-13C6,d7 is a stable isotope-labeled form of D-Glucose, incorporating both deuterium and carbon-13 isotopes. This compound serves as a valuable tracer in metabolic studies, aiding in the investigation of carbohydrate metabolism and metabolic flux analysis. Its unique isotopic composition allows for precise tracking of glucose utilization in various biological systems, making it a critical reagent for researchers studying energy metabolism and cellular processes. -
Stable Isotope
Sulfamethazine-d4 is a deuterium-labeled derivative of Sulfamethazine, a sulfonamide antibiotic. This stable isotope is primarily used for research applications, including pharmacokinetic studies and metabolic tracing in biological systems. Sulfamethazine itself is utilized for its antimicrobial properties, particularly in treating and preventing gastrointestinal and respiratory infections in animals. -
Stable Isotope
α-Terpineol-d3 is a deuterium-labeled derivative of α-Terpineol, a compound derived from Eucalyptus globulus. This stable isotope retains the strong antimicrobial properties of α-Terpineol, demonstrating significant activity against periodontopathic and cariogenic bacteria, as well as antifungal effects against Trichophyton mentagrophytes. Its unique labeling makes it valuable in research applications focused on microbial interactions and cellular disruption mechanisms. -
Stable Isotope
Nonanoic acid-d4 is a deuterium-labeled derivative of nonanoic acid, a naturally occurring saturated fatty acid with nine carbon atoms. This stable isotope is utilized in various research applications to study metabolic processes and fatty acid metabolism. Nonanoic acid has been shown to significantly reduce bacterial translocation, enhance antibacterial activity, and increase the secretion levels of porcine β-defensins 1 (pBD-1) and pBD-2, making it valuable for investigations into antimicrobial peptides and gut health. -
Stable Isotope
D-Sorbitol-13C6 is a stable isotope-labeled form of D-Sorbitol, a six-carbon sugar alcohol. This compound serves as a versatile stabilizing excipient and isotonicity agent, making it suitable for various formulations. It is often utilized in biological research to trace metabolic pathways and assess carbohydrate metabolism, providing valuable insights into biochemical processes. D-Sorbitol-13C6 is also employed extensively in dietary supplement research and food science applications. -
Stable Isotope
Urethane-d5 is a deuterium-labeled version of Urethane, which is the ethyl ester of carbamic acid. It is commonly utilized in studies involving fermentation and food products. Urethane is known to inhibit the growth of bacteria, protozoa, sea urchin eggs, and plant tissues in vitro, making it valuable for various research applications in microbiology and botany. -
Stable Isotope
Tridecanoic acid-d25 is a deuterated form of tridecanoic acid, a medium-chain saturated fatty acid consisting of 13 carbon atoms. This compound acts as an antipersister and antibiofilm agent, demonstrating significant inhibitory effects on the persistence and biofilm formation of Escherichia coli. Its unique properties make it a valuable tool in research focused on bacterial infections and the development of strategies to combat biofilm-related challenges. -
Stable Isotope
Saccharin-d4 is a deuterium-labeled form of saccharin, a widely used non-caloric artificial sweetener. As a stable isotope, Saccharin-d4 serves as a valuable tracer in metabolic studies and research involving dietary components. Its unique isotopic signature allows for enhanced tracking of saccharin's effects on microbiome modulation and bacteriostatic activity in various biological systems. -
Stable Isotope
Mandelic acid-2,3,4,5,6-d5 is a deuterium-labeled variant of mandelic acid, an alpha-hydroxycarboxylic acid. This stable isotope serves as a valuable tool in tracing studies and metabolic research. Mandelic acid demonstrates antimicrobial properties and has applications in the study of urinary tract infections and vaginal trichomoniasis. Additionally, it is known for its high sperm-immobilizing activity while minimizing vaginal irritation, making it relevant for reproductive health research. -
Stable Isotope
Nonanoic acid-d2 is the deuterium-labeled derivative of nonanoic acid, a saturated fatty acid comprising nine carbon atoms. This compound plays a critical role in metabolic studies and tracing experiments due to its stable isotope labeling. Research indicates that nonanoic acid exhibits significant antibacterial properties, reduces bacterial translocation, and enhances the secretion of porcine β-defensins 1 and 2, making it a valuable tool in studies of intestinal health and antimicrobial peptide function. -
Stable Isotope
Thymol-d13 is a deuterated form of Thymol, a key monoterpene phenol primarily found in essential oils from the Lamiaceae family as well as various other plant families, including Verbenaceae, Scrophulariaceae, Ranunculaceae, and Apiaceae. This stable isotope is utilized in research to trace pathways and quantify metabolites in biological systems. Thymol exhibits notable biological activities, including antioxidant, anti-inflammatory, antibacterial, and antifungal properties, making it relevant for studies in pharmacology and biochemistry. -
Stable Isotope
Octacosane-d58 is the deuterated form of octacosane, a long-chain hydrocarbon with antibacterial properties. This stable isotope is valuable for studies investigating the metabolic pathways and biological activities of octacosane. Notably, octacosane exhibits considerable cytotoxicity against murine melanoma B16F10-Nex2 cells and provides protective effects in subcutaneous melanoma models. Additionally, it demonstrates larvicidal activity against the mosquito Culex quinquefasciatus, with an LC50 of 7.2 mg/L, making it a useful compound for research in both cancer biology and pest control. -
Stable Isotope
Vitamin D3-d7 is a deuterium-labeled form of Vitamin D3 (Cholecalciferol), enabling precise tracking in metabolic studies. It is known to promote cell differentiation and inhibit the proliferation of cancer cells, making it a valuable tool in cancer research. This stable isotope is particularly useful for pharmacokinetic studies and the investigation of vitamin D metabolism in biological systems. -
Stable Isotope
Benzothiazole-d4 is a stable isotope-labeled form of Benzothiazole, a naturally occurring heterocyclic compound. This reagent is widely utilized in biological research due to its diverse activities, including anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral properties. Benzothiazole-d4 is particularly valuable for tracing studies and metabolic profiling in various biological systems. -
Stable Isotope
Butylparaben-d4 is a deuterium-labeled derivative of Butylparaben, an organic compound recognized for its effective antimicrobial properties. This reagent is primarily utilized as a stable isotope in chemical research, allowing for the tracing and quantification of Butylparaben in various applications, including cosmetics, pharmaceuticals, and food products. Its stability and unique labeling make it essential for studying the dynamics of antimicrobial preservation and understanding the compound's behavior in complex matrices. -
Stable Isotope
Ethylparaben-d4 is a deuterium-labeled analog of ethylparaben, primarily utilized as a stable isotope standard in analytical chemistry. This compound serves as an internal standard in mass spectrometry and other analytical techniques, facilitating precise quantification and analysis of ethylparaben and its metabolites in biological samples. Its unique isotopic signature enhances the accuracy of trace-level detection and study of paraben-related biological activity in various research applications. -
Stable Isotope
Robenidine-d8 hydrochloride is a deuterium-labeled analogue of Robenidine hydrochloride, primarily utilized as a stable isotope in research. As an effective anticoccidial agent, it exhibits biological activity against Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE), with MIC50 values of 8.1 µM and 4.7 µM, respectively. This compound is valuable for studies investigating coccidiosis and antibiotic resistance in bacterial pathogens. -
Stable Isotope
Lauric acid-d2 is a deuterium-labeled form of lauric acid, a medium-chain fatty acid known for its potent bactericidal activity. It exhibits effective antibacterial properties against Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis, with EC50 values of 2, 6, and 4 μg/mL, respectively. This stable isotope is valuable for research applications in microbiology and lipid metabolism studies, enabling the elucidation of fatty acid metabolism and the investigation of antimicrobial mechanisms. -
Stable Isotope
(±)-Leucine-d7 is a deuterium-labeled form of (±)-Leucine, a proteinogenic amino acid. This stable isotope is useful for tracing pathways in metabolic studies, particularly in the analysis of amino acid metabolism and protein synthesis. (±)-Leucine exhibits inhibitory effects on the growth of Escherichia coli HfrH, making it relevant for research involving bacterial cultures and metabolic inhibition. -
Stable Isotope
Triclocarban-d4 is the deuterated form of Triclocarban, a triclocarban compound functioning as a broad-spectrum antibacterial agent. This stable isotope is utilized in various applications, including the formulation of personal care products such as soaps, skin creams, and deodorants. Triclocarban has been identified as a potential endocrine disruptor, capable of affecting androgen and estrogen activity, thereby influencing hormone-mediated biological processes in research studies. -
Isotope-Labeled Compounds
Ethyl acetoacetate-d3 is a deuterium-labeled isotopologue of ethyl acetoacetate. This ester serves as a valuable intermediate in the synthesis of diverse organic compounds. Additionally, ethyl acetoacetate demonstrates bioactivity as an inhibitor of bacterial biofilm formation, making it useful for research applications in microbiology and pharmaceutical development. -
Stable Isotope
Nonanoic acid-d3 is a deuterated analog of nonanoic acid, a naturally occurring saturated fatty acid comprising nine carbon atoms. This stable isotope serves as a useful tracer in metabolic studies and is valuable in research focusing on lipid metabolism, fatty acid absorption, and microbial interactions. Nonanoic acid has been shown to reduce bacterial translocation, enhance antibacterial activity, and increase the secretion of important antimicrobial peptides, specifically porcine β-defensins 1 and 2. -
Stable Isotope
Levulinic acid-d5 is a deuterium-labeled derivative of levulinic acid, primarily used as a stable isotope in chemical research. This compound serves as an important precursor for the synthesis of biofuels, particularly ethyl levulinate, enabling studies on metabolic pathways and the mechanisms of biofuel production. Its unique isotopic labeling facilitates advanced analytical techniques, including mass spectrometry and NMR, making it a valuable tool for researchers in the field of sustainable energy and organic synthesis. -
Stable Isotope
Rac cis-Moxifloxacin-d4 hydrochloride is a deuterated form of the antibiotic moxifloxacin, specifically designed for use as a stable isotope. This compound retains the properties of moxifloxacin, an 8-methoxyquinolone antimicrobial that targets bacterial infections, including acute bacterial sinusitis and pneumonia. Its stable isotope labeling is beneficial for pharmacokinetic studies, metabolic tracking, and the development of analytical techniques in medicinal chemistry. -
Stable Isotope
Clindamycin Hydrochloride-13C,d3 is a stable isotope-labeled form of Clindamycin hydrochloride, incorporating deuterium and 13C. As a semisynthetic lincosamide antibiotic, it inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit. This reagent is valuable for studying drug metabolism, pharmacokinetics, and antibiotic resistance in various biological research applications. -
Stable Isotope
Sulfadoxine-d4 is a deuterium-labeled derivative of Sulfadoxine, a long-acting sulfonamide antibiotic. It primarily targets dihydropteroate synthase, inhibiting folate synthesis in bacterial cells. Due to its mechanism of action, Sulfadoxine-d4 demonstrates significant antibacterial activity and is employed in research focused on respiratory and urinary tract infections, as well as malaria. Additionally, it has been shown to inhibit HIV replication in peripheral blood mononuclear cells, making it a valuable tool for studies in antiviral research. -
Stable Isotope
Raja 42-d10 is a deuterated form of the gamma-lactam antibiotic Raja 42, designed for studied isotopic labeling applications. This stable isotope exhibits potent antibacterial activity against a range of bacteria, including both Gram-positive and Gram-negative strains, with notable efficacy against C. difficile. Raja 42-d10 is essential for research involving metabolic studies, pharmacokinetics, and the elucidation of mechanistic pathways in bacterial infections. -
Stable Isotope
Sulfamonomethoxine-13C6 is a stable isotope-labeled derivative of the sulfonamide antibiotic sulfamonomethoxine, primarily known for its role in veterinary medicine. This compound functions as a dihydropteroate synthetase inhibitor, effectively disrupting folic acid synthesis and exhibiting antibacterial properties. It serves as a valuable tool in biochemical research, particularly in studies involving antibiotic efficacy and metabolic pathways. -
Stable Isotope
Desmethyl Levofloxacin-d8 is a deuterated form of Desmethyl Levofloxacin, a key metabolite of Levofloxacin. This synthetic fluoroquinolone antibiotic exerts its biological activity by inhibiting bacterial DNA gyrase, thereby disrupting DNA supercoiling and interfering with DNA replication. Desmethyl Levofloxacin-d8 serves as a valuable stable isotope labeled reagent for pharmacokinetic studies and analytical applications in drug metabolism research. -
Stable Isotope
Sulfanilamide-d4 is a stable isotope-labeled derivative of sulfanilamide, specifically designed for quantitative studies. As a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase, sulfanilamide-d4 demonstrates an IC50 of 320 μM. This reagent is utilized in biochemical research to trace metabolic pathways and assess the activity of dihydropteroate synthetase in microbial systems. -
Stable Isotope
Valacyclovir-d8 hydrochloride is a deuterated analog of Valacyclovir hydrochloride, serving as a stable isotope for advanced research applications. This compound exhibits potent antiviral activity against herpes simplex virus type 1 (HSV-1) with an IC50 of 2.9 μg/ml, making it a valuable tool in studying viral infections. Valacyclovir functions as a prodrug of Acyclovir, facilitating studies on pharmacokinetics and metabolism in virology and clinical research contexts. -
Stable Isotope
2-Thiophenecarboxaldehyde-d3 is a deuterium-labeled derivative of 2-Thiophenecarboxaldehyde. This stable isotope is used as an internal standard in analytical chemistry and pharmacokinetic studies. Its primary application lies in the investigation of antibacterial and nematicidal properties, contributing valuable insights to chemical research in microbiology and pest control. -
Stable Isotope
Sarafloxacin-d8 hydrochloride is a deuterium-labeled derivative of the quinolone antibiotic Sarafloxacin. This stable isotope reagent enables investigations into the drug's pharmacokinetics and metabolic pathways. It is widely applicable in tracing studies and mass spectrometry, facilitating enhanced understanding of antibiotic behavior in biological systems. -
Stable Isotope
Nitrofurantoin-13C3 is a stable isotope-labeled form of Nitrofurantoin, a broad-spectrum antimicrobial agent known for its effectiveness against beta-lactamase-producing bacteria. This compound functions as an antibiotic, primarily employed in the study and treatment of urinary tract infections (UTIs), including cystitis and pyelonephritis. The stable isotope labeling allows for enhanced tracking and quantification in pharmacokinetic and metabolic studies. -
Stable Isotope
Moxifloxacin-d3-1 hydrochloride is a deuterium-labeled derivative of Moxifloxacin, an 8-methoxyquinolone antibiotic. This stable isotope serves as a valuable analytical tool in pharmacokinetic studies and metabolic profiling of Moxifloxacin. It is particularly useful in research applications focused on understanding the drug's metabolic pathways, efficacy against bacterial infections, and its role in treating conditions such as acute bacterial sinusitis and community-acquired pneumonia. -
Stable Isotope
Flumequine-13C3 is a stable isotope-labeled variant of flumequine, a quinolone antibiotic known for its ability to inhibit topoisomerase II with an IC50 of 15 μM (3.92 μg/mL). This compound is essential for research involving metabolic studies and drug metabolism, enabling precise tracking and analysis of flumequine's biochemical interactions within biological systems. Its stable isotope label makes it particularly useful in mass spectrometry applications and pharmacokinetic studies. -
Stable Isotope
2-(α-D-Mannopyranosyl)-L-tryptophan-d4 is a stable isotope-labeled derivative of 2-(α-D-Mannopyranosyl)-L-tryptophan, facilitating enhanced analysis in metabolic studies. This compound serves as a valuable tool for tracing metabolic pathways and studying glycoprotein interactions in biochemical research. Its deuterium labeling aids in quantifying and tracking molecules in complex biological systems, making it an essential reagent for researchers in the fields of glycoscience and pharmacology. -
Stable Isotope
Sulfamonomethoxine-d3-1 is a deuterium-labeled derivative of Sulfamonomethoxine, functioning primarily as a stable isotope. This compound serves as an orally active sulfonamide antibiotic utilized in veterinary medicine, exhibiting antibacterial activity. By inhibiting dihydropteroate synthetase, Sulfamonomethoxine-d3-1 effectively disrupts folic acid synthesis, making it a valuable reagent for research applications involving antibiotic activity and metabolic studies. -
Stable Isotope
Moxifloxacin-d3 hydrochloride is a deuterium-labeled derivative of the antibiotic Moxifloxacin hydrochloride, designed for stable isotope applications in research. This compound retains the antimicrobial activity of the original Moxifloxacin, which is effective in treating infections such as acute bacterial sinusitis, exacerbations of chronic bronchitis, and community-acquired pneumonia. Moxifloxacin-d3 hydrochloride is valuable for pharmacokinetic studies and metabolic research involving isotopic tracing. -
Stable Isotope
Ertapenem-d4 is a deuterium-labeled derivative of the broad-spectrum β-lactam antibiotic Ertapenem. This compound exhibits potent antibacterial activity, particularly against a variety of anaerobic bacteria, with a minimum inhibitory concentration (MIC) of 0.12 μg/mL. Ertapenem-d4 is useful in research applications focused on the pharmacokinetics and metabolic pathways of β-lactam antibiotics, as well as studies involving severe bacterial infections in diverse anatomical sites including the skin, lungs, stomach, pelvis, and urinary tract. -
Stable Isotope
Aprepitant-13C2,d2 (Major) is a stable isotope-labeled variant of Aprepitant, a selective and high-affinity antagonist of the neurokinin 1 receptor with a dissociation constant (Kd) of 86 pM. This reagent is primarily utilized in pharmacokinetic studies and metabolic research. The 13C labeling allows for precise tracing and quantification in complex biological systems, facilitating a deeper understanding of Aprepitant's biochemical interactions and tissue distribution. -
Stable Isotope
Tiamulin-d10-1 hydrochloride is a deuterium-labeled derivative of the diterpenic antibiotic Tiamulin. Its primary mechanism targets bacterial protein synthesis, making it crucial in research involving infectious diseases in livestock, particularly in the control of Mycoplasma spp. Tiamulin is commonly utilized in studies of airsacculitis, facilitating enhanced understanding of antibiotic efficacy and resistance mechanisms in veterinary medicine. -
Stable Isotope
Gatifloxacin-d4 hydrochloride is a deuterium-labeled analog of Gatifloxacin, primarily utilized as a stable isotope in chemical and biological research. This reagent is valuable for pharmacokinetic studies, metabolic profiling, and trace analysis in complex biological matrices. Its incorporation of deuterium allows for enhanced detection and quantification in mass spectrometry applications, facilitating the study of drug interactions and metabolic pathways. -
Stable Isotope
(R)-2-Methylbutanoic acid-d3 is a deuterium-labeled derivative of (R)-2-Methylbutanoic acid, serving as a stable isotope used in various research applications. This compound aids in metabolic studies, trace analysis, and isotope labeling experiments, allowing for enhanced sensitivity and specificity in quantitative analysis. Its use in nuclear magnetic resonance (NMR) and mass spectrometry provides valuable tools for probing biochemical pathways and mechanisms. -
Stable Isotope
Sulfisomidin-d4 is a deuterium-labeled derivative of Sulfisomidin, a sulfonamide antibacterial with oral bioavailability. This compound primarily targets bacterial dihydropteroate synthase, inhibiting folate synthesis and demonstrating antibacterial activity. Sulfisomidin-d4 is useful for research applications involving lower urinary tract infections, providing a valuable tool for studying pharmacokinetics and metabolic pathways of sulfonamide antibiotics. -
Stable Isotope
(Rac)-Moxifloxacin-d4 is a deuterium-labeled derivative of (Rac)-Moxifloxacin, an 8-methoxyquinolone antimicrobial. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research to trace and quantify the drug's behavior in biological systems. Its applications extend to investigating the efficacy of antibacterial therapies against pathogens responsible for respiratory infections, such as acute bacterial sinusitis and pneumonia. -
Stable Isotope
Moxifloxacin-d5 is a deuterium-labeled derivative of Moxifloxacin, an 8-methoxyquinolone antibiotic. This stable isotope is utilized in pharmacokinetic studies and metabolic research to trace the behavior of Moxifloxacin in biological systems. It is particularly relevant for investigations into its action against acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia. -
Stable Isotope
Nalidixic Acid-d5 is a deuterium-labeled derivative of nalidixic acid, a quinolone antibiotic that targets DNA gyrase and topoisomerase IV. This compound exhibits bacteriostatic activity at lower concentrations and demonstrates bactericidal effects at higher concentrations against a broad spectrum of gram-positive and gram-negative bacteria. Nalidixic Acid-d5 is utilized in research applications involving antibiotic resistance studies, bacterial DNA replication mechanisms, and pharmacokinetic investigations.
