Gatifloxacin-d4 is a deuterium-labeled derivative of the fluoroquinolone antibiotic Gatifloxacin, which primarily targets bacterial topoisomerases II. It exhibits broad-spectrum antibacterial activity, with IC50 values of 13.8 μg/mL against S. aureus topoisomerase IV and 0.109 μg/mL for E. coli DNA gyrase. This stable isotope-labeled compound is suitable for investigative research into bacterial infections, particularly in studies related to bacterial conjunctivitis.
Gatifloxacin-d4 is a deuterium-labeled derivative of the fluoroquinolone antibiotic Gatifloxacin, which primarily targets bacterial topoisomerases II. It exhibits broad-spectrum antibacterial activity, with IC50 values of 13.8 μg/mL against S. aureus topoisomerase IV and 0.109 μg/mL for E. coli DNA gyrase. This stable isotope-labeled compound is suitable for investigative research into bacterial infections, particularly in studies related to bacterial conjunctivitis.
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