LDN193189 Tetrahydrochloride

Catalog No.: A21881

BMP type I receptor inhibitor

LDN193189 Tetrahydrochloride

LDN193189 Tetrahydrochloride Chemical Structure

CAS NO. 2310134-98-4

LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM).

Availability: In stock

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5 mg

Regular Price: $76.00

Special Price $60.80

10 mg

Regular Price: $130.00

Special Price $104.00

50 mg

Regular Price: $386.00

Special Price $308.80

100 mg

Regular Price: $773.00

Special Price $618.40

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Biological Activity

LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.11 mL 90.53 mL 181.05 mL
0.5 mM 3.62 mL 18.11 mL 36.21 mL
1 mM 1.81 mL 9.05 mL 18.11 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21881
Actions Inhibitor
CAS No. 2310134-98-4
Formula C25H26Cl4N6
M. Wt 552.33
Purity >98%
Synonyms LDN 193189, LDN193189
SMILES C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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