LDN193189 Tetrahydrochloride

Catalog No.: A21881

BMP type I receptor inhibitor

LDN193189 Tetrahydrochloride

LDN193189 Tetrahydrochloride Chemical Structure

CAS NO. 2310134-98-4

LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM).

Availability: In stock

Package Price Qty
5 mg
$76.00
10 mg
$130.00
50 mg
$386.00
100 mg
$773.00
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Biological Activity

LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50??500 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.11 mL 90.53 mL 181.05 mL
0.5 mM 3.62 mL 18.11 mL 36.21 mL
1 mM 1.81 mL 9.05 mL 18.11 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21881
Actions Inhibitor
M. Wt 552.33
Formula C25H26Cl4N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2310134-98-4
Synonyms LDN 193189, LDN193189
SMILES C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl.Cl.Cl

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