LDN193189
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | LDN193189 is a highly potent small molecule BMP inhibitor that inhibits BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation. | ||
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Targets |
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Catalog Num | A11205 |
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Formula | C25H22N6 |
Molecular Weight | 406.48 |
CAS Number | 1062368-24-4 |
SMILES | C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3 |
Synonyms | LDN-193189 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Insoluble | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.6 mL | 123.01 mL | 246.01 mL |
0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2