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- Bo Pang, .et al. Elevated Notch1 enhances interleukin-22 production by CD4+ T cells via aryl hydrocarbon receptor in patients with lung adenocarcinoma, Biosci Rep, 2018, Dec 21; 38(6): BSR20181922 PMID: 30473538
- Shuo Li, .et al. Notch signaling pathway suppresses CD8+ T cells activity in patients with lung adenocarcinoma, Int Immunopharmacol, 2018, Oct;63:129-136 PMID: 30086535
- Jiang BC, .et al. Notch Signaling Regulates Circulating T Helper 22 Cells in Patients with Chronic Hepatitis C, Viral Immunol, 2017, Sep;30(7):522-532 PMID: 28410452
|Storage||at -20°C 3 years Powder|
|SMILES code||C[[email protected]@H](C(=O)N[[email protected]]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[[email protected]](C4=CC(=CC(=C4)F)F)O|
LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.
|Solubility (25°C) *||In vitro||DMSO||95 mg/mL (198.13 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||95 mg/mL (198.13 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||20.86 mL||104.28 mL||208.56mL|
|0.5 mM||4.17 mL||20.86 mL||41.71 mL|
|1 mM||2.09 mL||10.43 mL||20.86 mL|
|5 mM||0.42 mL||2.09 mL||4.17 mL|
*The above data is based on the productmolecular weight 479.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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