LY-411575

Catalog No.: A11176
Gamma secretase inhibitor

LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.

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Product Name Price Stock Qty
LY-411575 5mg
Special Price $52.00 Regular Price $65.00
In stock
LY-411575 10mg
Special Price $88.00 Regular Price $110.00
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LY-411575 50mg
Special Price $344.00 Regular Price $430.00
In stock
LY-411575 100mg
Special Price $532.00 Regular Price $665.00
In stock
LY-411575 10mM * 1mL in DMSO
Special Price $80.00 Regular Price $100.00
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Adooq Products cited in reputable paper
Adooq's LY-411575 has been cited by 6 publications
  • Haiwen Yu, .et al. , Immunol Invest, 2023, Feb;52(2):241-255 PMID: 36562737
  • Wojciech J Szlachcic, .et al. , iScience, 2022, Jul 15;25(7) PMID: 35756892
  • Zhang ZH, .et al. , APMIS, 2019, Jul 5 PMID: 31274210
  • Bo Pang, .et al. , Biosci Rep, 2018, Dec 21; 38(6): BSR20181922 PMID: 30473538
  • Shuo Li, .et al. , Int Immunopharmacol, 2018, Oct;63:129-136 PMID: 30086535
  • Jiang BC, .et al. , Viral Immunol, 2017, Sep;30(7):522-532 PMID: 28410452
  • Biological Activity
    Discription

    LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.

    Targets
    Target Value
    Product Information
    Catalog Num A11176
    Formula C26H23F2N3O4
    Molecular Weight 479.48
    CAS Number 209984-57-6
    SMILES C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C4=CC(=CC(=C4)F)F)O
    Synonyms LY411575
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 94 mg/mL (196.04 mM)
    Water Insoluble
    Ethanol 13 mg/mL (27.11 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.86 mL 104.28 mL 208.56 mL
    0.5 mM 4.17 mL 20.86 mL 41.71 mL
    1 mM 2.09 mL 10.43 mL 20.86 mL
    5 mM 0.42 mL 2.09 mL 4.17 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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