LY-411575

Name: LY-411575
SKU: A11176
Price: 30 USD
Rating: 5 (6 reviews)

Catalog No.: A11176

Gamma secretase inhibitor

Adooq's LY-411575 has been cited by 6 publications

LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.

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Grouped product items
Size	Price	Stock
2mg	$30.00	In stock
5mg	$55.00	In stock
10mg	$100.00	In stock
25mg	$215.00	In stock
50mg	$425.00	In stock
100mg	$630.00	In stock
*10mM 1mL in DMSO**	$55.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Adooq Products cited in reputable paper

Adooq's LY-411575 has been cited by 6 publications

Haiwen Yu, .et al. , Immunol Invest, 2023, Feb;52(2):241-255 PMID: 36562737

Wojciech J Szlachcic, .et al. , iScience, 2022, Jul 15;25(7) PMID: 35756892

Zhang ZH, .et al. , APMIS, 2019, Jul 5 PMID: 31274210

Bo Pang, .et al. , Biosci Rep, 2018, Dec 21; 38(6): BSR20181922 PMID: 30473538

Shuo Li, .et al. , Int Immunopharmacol, 2018, Oct;63:129-136 PMID: 30086535

Jiang BC, .et al. , Viral Immunol, 2017, Sep;30(7):522-532 PMID: 28410452

Biological Activity

Discription

LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A11176
Formula	C26H23F2N3O4
Molecular Weight	479.48
CAS Number	209984-57-6
SMILES	C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C4=CC(=CC(=C4)F)F)O
Synonyms	LY411575
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	94 mg/mL (196.04 mM)
	Water	Insoluble
	Ethanol	13 mg/mL (27.11 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.86 mL	104.28 mL	208.56 mL
0.5 mM	4.17 mL	20.86 mL	41.71 mL
1 mM	2.09 mL	10.43 mL	20.86 mL
5 mM	0.42 mL	2.09 mL	4.17 mL

Useful Calculator

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