Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Armeniaspirol B is a selective antibiotic that primarily targets Gram-positive pathogens. It exhibits minimal inhibitory concentration (MIC) values of 0.5 μg/mL against Staphylococcus aureus Newman and 2.0 μg/mL against Staphylococcus aureus USA300. This compound is of particular interest for research focused on Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) infections. -
Antibiotic
TMC-169 is a potent antibiotic belonging to the Aspochalasin group, isolated from Aspergillus flavipes. This compound demonstrates significant anti-tumor activity across various cancer cell types, making it relevant for research into hematologic malignancies, non-small cell lung cancer, breast cancer, and glioma. TMC-169 serves as a valuable tool for exploring therapeutic strategies against these malignancies. -
Bacteriostatic Antibiotic
Trimethoprim sulfate is a potent bacteriostatic antibiotic that functions primarily as a dihydrofolate reductase inhibitor. It exhibits broad-spectrum activity against various Gram-positive and Gram-negative aerobic bacteria, making it valuable in the study of urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim sulfate has demonstrated potential in inhibiting Influenza A virus infection in chick embryos when used in combination with zinc, highlighting its multifaceted applications in microbial research. -
Antibiotic/Antimicrobial Peptide
Aurein 2.2 is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria including Staphylococcus aureus and S. epidermidis. Isolated from the skin secretions of L. aurea, Aurein 2.2 demonstrates potential as an effective antibiotic, making it a valuable tool for research in microbiology and antimicrobial therapy. Its unique mechanism of action and efficacy against resistant strains underline its relevance in the study of infection control and antibiotic development. -
Macrolide Antibiotic
Aldgamycin G is a macrolide antibiotic that targets Gram-positive bacteria. Isolated from Streptomyces avidinii, it exhibits significant antibacterial activity, making it a valuable compound for research in microbiology and antibiotic resistance studies. Its mechanism of action involves inhibition of bacterial protein synthesis, enhancing its utility in the investigation of microbial pathogenicity and treatment options against Gram-positive infections. -
Antibiotic
LL-Z1220 is a novel antibiotic targeting bacterial cell integrity. Featuring a unique 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one structure, it represents the first known natural product containing a benzene dioxide group. LL-Z1220 exhibits valence isomerization, forming 1,4-dioxopentacyclo, with spectral properties indicating a cis configuration of the benzene dioxide moiety. Its distinctive mechanism and structure make it a valuable compound for antibiotic research and development. -
Antibiotic
Daunosamnyl-daunorubicin is an antibiotic that binds to calf thymus DNA, exhibiting significant intercalation properties. This compound is primarily utilized in research focused on anticancer therapies and the study of DNA-drug interactions. Its mechanism of action involves disrupting the normal functioning of DNA, making it valuable for investigations into its therapeutic efficacy against various malignancies. -
Quinolone Antibiotic
Lomefloxacin (aspartate) targets bacterial DNA gyrase, exhibiting potent antibacterial activity as a broad-spectrum quinolone antibiotic. It is effective against a wide range of bacterial pathogens and is utilized in research concerning respiratory tract infections, genitourinary infections, gastrointestinal infections, and ENT infections. Its mechanism of action disrupts bacterial DNA replication, making it a valuable tool for investigating antibiotic resistance and treatment efficacy. -
Antibiotic
Spiramycin (hexanedioate) is a macrolide antibiotic derived from Streptomyces ambofaciens, primarily targeting bacterial infections and Toxoplasma gondii. Its chemical structure features a 16-membered lactone ring with three sugar moieties: mycaminose, forosamine, and mycarose. Spiramycin exhibits significant antibacterial and antiparasitic activity, making it valuable in the study of infectious diseases and potential therapeutic applications. -
Antibiotic
BAL-19403 is a macrolide antibiotic that primarily targets bacterial infections. It demonstrates potent activity against Propionibacterium acnes, specifically against strains resistant to erythromycin and clindamycin. BAL-19403 exhibits both antibacterial and anti-inflammatory properties, making it a valuable reagent for research focused on acne treatment and related inflammatory skin conditions. -
Antibiotic
BU-2313 A is an antibiotic that exhibits antimicrobial activity through its unique dienoyltetraamide acid structure. This compound is related to streptolysin and tilamycin, making it a valuable tool for studying bacterial resistance mechanisms and evaluating potential therapeutic strategies. Its efficacy in combating bacterial infections positions it as a relevant candidate for research in antimicrobial drug development. -
Peptide Antibiotic
Angiotensin III antipeptide is a peptide antibiotic that inhibits the activity of angiotensin II, a key regulator in the renin-angiotensin system. It exhibits biological activity by modulating blood pressure and fluid balance, making it a valuable tool in cardiovascular and renal research. Its applications include studying the effects of angiotensin peptides on physiological processes and exploring potential therapeutic interventions in related diseases. -
Antitumor Antibiotic
Kapurimycin A2 is an antitumor antibiotic derived from the culture of Streptomyces sp., primarily targeting bacterial infections. It exhibits notable antibacterial activity, particularly against Gram-positive bacteria. This compound is utilized in research applications to investigate its potential therapeutic effects in tumor treatment and microbial resistance studies. -
Antibiotic
A2315A, also known as Madumycin II, is an alanine-containing streptogramin A antibiotic that functions as a potent inhibitor of the peptidyl transferase center (PTC) within the ribosome. By targeting the ribosomal machinery, A2315A effectively prevents the initiation of the first cycle of peptide bond formation, demonstrating significant antibiotic activity. This compound is valuable for research focusing on ribosomal function and antibiotic mechanism of action. -
Antibiotic/Antimicrobial Peptide
Aurein 2.6 is an antimicrobial peptide that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, with minimum inhibitory concentrations (MIC) of 25 to 30 μM against various strains, including Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Bacillus subtilis. Aurein 2.6 is valuable for research applications involving antibiotic resistance studies and the development of new antimicrobial agents. -
Antibiotic
Okilactomycin is a lactone antibiotic derived from the culture filtrate of Streptomyces species. It exhibits antibacterial activity by inhibiting bacterial growth mechanisms, making it valuable for studying antibiotic resistance and bacterial infections. This compound can be utilized in research related to microbiology and pharmacology to further understand antibiotic properties and develop new therapeutic strategies. -
Antibiotic
Boromycin is an antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. Isolated from Streptomyces antibioticus, it exhibits potent activity against a range of gram-positive bacteria. This compound is valuable for research applications related to antimicrobial resistance and the development of new therapeutic agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibiotic
Altersolanol B, a fungal-derived compound, exhibits antibiotic properties through its ability to induce ATP catabolism in Ehrlich ascites tumor cells. This molecular action highlights its potential as a research tool for studying cellular energy dynamics and responses to antimicrobial agents. Altersolanol B may contribute to the understanding of antibiotic mechanisms and resistance patterns in cancer biology. -
Antibiotic
Ranbezolid is an orally active oxazolidinone antibiotic primarily targeting Gram-positive and Gram-negative anaerobes, including Staphylococcus aureus and Bacteroides fragilis. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, demonstrating an IC50 of 17 μM. Ranbezolid is effective in rapidly reducing bacterial load and has an enhanced cardiovascular safety profile. This compound is valuable for research applications focused on antibiotic effects against anaerobic bacteria. -
Sulfur-containing Antibiotic
Tropodithietic acid is a sulfur-containing antibiotic derived from the marine bacterium Phaeobacter inhibens. It demonstrates potent antibacterial activity against a wide range of bacterial species, including alpha- and gammaproteobacteria, flavobacteria, and actinobacteria. This compound is valuable for research applications involving antimicrobial resistance and the study of microbial interactions in marine environments. -
Antibiotic, Insecticide
Cafamycin is a polyether antibiotic that targets gram-positive bacteria, notably Staphylococcus aureus. In addition to its antibacterial properties, Cafamycin exhibits insecticidal and antiprotozoal activities. It is isolated from the culture fluid of Streptomyces sp., an organism recognized for producing various bioactive compounds, including the anthracycline antibiotic galtamycin. This compound is valuable for research applications in microbiology and pest control. -
Antibiotic
Avilamycin A is an orally active antibiotic that targets bacterial pathogens, particularly effective against veterinary strains of Clostridium perfringens (MICs ≤ 0.06-0.5 mg/L) and Brachyspira hyodysenteriae (MICs = 12.5-100 μg/ml). Its potent antibacterial properties make it a valuable reagent for research focused on combating bacterial infections in veterinary medicine. Avilamycin A is often utilized in studies aiming to understand antibiotic resistance mechanisms and to develop new therapeutic strategies against resistant bacterial strains. -
Antibiotic
(R)-10,11-Dehydrocurvularin is an antibiotic derived from the secondary metabolites of Curvularia species. It exhibits concentration-dependent cytotoxicity against various human tumor cell lines, with a mean IC50 value of 1.25 µM. This compound is valuable for research applications in cancer biology and the development of novel antimicrobial agents. -
Antibiotic
Erythromycin C is an antibiotic that primarily targets bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits potent activity against a wide range of gram-positive bacteria and some gram-negative pathogens. Erythromycin C is widely used in research to study bacterial resistance mechanisms and as a model compound in antibiotic development studies. Its properties make it a valuable tool in microbiological and pharmaceutical research. -
Antibiotic
Concanamycin A is a macrolide antibiotic that functions as an inhibitor of vacuolar type H+-ATPase (V-ATPase). By inhibiting V-ATPase, Concanamycin A disrupts lysosomal acidification, making it a valuable tool in the study of T cell-mediated inflammation. Its properties allow for exploration of cellular processes related to inflammation and lysosomal function, contributing to a better understanding of various disease mechanisms. -
Antibiotic
Streptomycin is an aminoglycoside antibiotic primarily targeting bacterial protein synthesis by binding to ribosomal RNA. It exhibits potent activity against Mycobacterium tuberculosis, making it essential for tuberculosis research. In addition, Streptomycin demonstrates bactericidal properties against various bacterial infections and interferes with nucleic acid interactions. Furthermore, this compound acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes, enabling its use in studies related to electrophysiological processes. -
Antibiotic
Amythiamicin C is an antimicrobial antibiotic that primarily targets Gram-positive bacteria, including strains of methicillin-resistant Staphylococcus aureus (MRSA). Additionally, it exhibits activity against Plasmodium falciparum, making it valuable for research in infectious diseases and antibiotic resistance. This compound is relevant for studies focused on the development of novel therapeutic strategies against resistant bacterial infections and malaria. -
Antibiotic
A51493A is an anthracyclinone antibiotic that exhibits potent antimicrobial activity against Gram-positive bacteria. This compound is useful in research applications focused on bacterial infections and exploring mechanisms of antibiotic resistance. Its unique structure and mode of action make it a valuable tool for studying antimicrobial efficacy and developing new therapeutic strategies. -
Antibiotic
Seldomycin factor 1 is an aminoglycoside antibiotic that targets bacterial protein synthesis. It exhibits a broad spectrum of antimicrobial activity against various Gram-positive and Gram-negative bacteria. This compound is valuable for research applications in microbiology and antibiotic resistance studies. -
Antibiotic
Chitinovorin C is a β-lactam antibiotic that primarily targets bacterial cell wall synthesis. It exhibits selective inhibitory activity against Gram-negative bacteria, making it a valuable tool in antibiotic research. This compound is utilized in studies aimed at understanding antibiotic resistance mechanisms and developing new therapeutic strategies against bacterial infections. -
Antibiotic
Spectinomycin sulfate hydrate is an antibiotic that primarily targets bacterial ribosomes to inhibit protein synthesis. It demonstrates broad-spectrum activity against various gram-positive and gram-negative organisms, making it a valuable tool in microbiological research. Additionally, Spectinomycin sulfate hydrate acts as a noncompetitive inhibitor of td intron RNA, with a reported Ki value of 7.2 mM, further expanding its utility in molecular biology studies. -
Antibiotic
Parvodicin B1 is a glycopeptide antibiotic that exerts its antimicrobial effects by inhibiting bacterial cell wall synthesis. It demonstrates significant activity against Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus, and Enterococcus faecalis. Parvodicin B1 is valuable in microbiological research and antibiotic susceptibility studies, providing insights into bacterial resistance mechanisms and antibiotic efficacy. -
Antibiotic
Sch 29482 is an orally active penem antibiotic that exhibits broad-spectrum antibacterial activity. This compound demonstrates effectiveness against a variety of Gram-positive and Gram-negative bacteria, making it a valuable tool for research into antibacterial treatments. Its unique mechanism of action interferes with bacterial cell wall synthesis, providing insights into antibiotic efficacy and resistance mechanisms. -
Antibiotic
Methacycline is a tetracycline antibiotic that primarily inhibits bacterial protein synthesis. It is recognized for its capacity to impede epithelial-to-mesenchymal transition (EMT) in vitro and to inhibit fibrogenesis in vivo, functioning independently of TGF-β1 Smad signaling pathways. Methacycline serves as an antimicrobial agent and demonstrates potential applications in the study of pulmonary fibrosis. -
Antibiotic
Pristinamycin II B is an ester peptide antibiotic that primarily targets Gram-positive bacteria. It exhibits potent antibacterial activity, making it a valuable reagent in studies focused on the treatment of infections caused by resistant strains. This compound is commonly utilized in research applications related to antibiotic resistance and the development of novel antimicrobial therapies. -
Antibiotic
Helvolinic acid is a steroidal antibiotic that targets Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it a valuable tool in the study of antimicrobial mechanisms and the development of new therapeutic agents. Its efficacy against resistant strains of bacteria positions it as a noteworthy reagent in antibiotic research and development. -
Antitumor Antibiotic
Menoxymycin B is an antitumor antibiotic that exhibits notable cytotoxic effects against cancer cells. It demonstrates potent inhibitory activity with IC50 values of 0.22 μM in KB cells and 0.023 μM in N18-RE-105 cells. This compound is valuable for cancer research, particularly in studies focused on cell proliferation and apoptosis mechanisms. -
Antibiotic
Minosaminomycin is an antibiotic that targets bacterial cells and is derived from the bacterium Streptomyces No. MA514A1. This compound demonstrates significant antimicrobial activity against Mycobacterium smegmatis ATCC 607 and Mycobacterium phlei, with minimum inhibitory concentrations (MIC) of 1.56 μg/mL and 6.25 μg/mL, respectively. Minosaminomycin is valuable for research applications focused on bacterial infections and the study of mycobacterial resistance. -
Antibiotic
Abbeymycin is an antibiotic derived from the actinobacterium Streptomyces sp. AB-999F-52, exhibiting potent antimicrobial activity primarily against anaerobic bacteria. Its specific action makes Abbeymycin a valuable tool in antibiotic discovery and screening research, aiding in the exploration of novel antimicrobial compounds. -
Antibiotic
Arylomycin B4 is a lipohexapeptide antibiotic specifically targeting Gram-positive bacteria. It demonstrates potent antimicrobial activity by inhibiting bacterial protein synthesis. This compound is valuable for research applications focused on the mechanisms of antibiotic resistance and the development of new antimicrobial agents. -
Antibiotic
Sapurimycin is an antitumor antibiotic derived from Streptomyces DO-116, belonging to the capramycin family. It demonstrates potent activity against Gram-positive bacteria and exhibits significant antitumor efficacy against leukemia P388 and sarcoma 180 in murine models. In vitro assays reveal that Sapurimycin induces single-strand breaks in supercoiled plasmid DNA, highlighting its potential utility in genomic studies and cancer research. -
Antibiotic
Cedarmycin A is an antibiotic with demonstrated efficacy against Candida species, Cryptococcus neoformans, and Aspergillus fumigatus, with minimum inhibitory concentration (MIC) values ranging from 12.5 to 50 μg/mL. It serves as a valuable research tool for investigating fungal infections and the development of antifungal therapies. Cedarmycin A's unique mechanism of action makes it an important compound for studying microbial resistance and host-pathogen interactions. -
Antitumor Antibiotic
Primocarcin is an antitumor antibiotic that specifically targets Ehrlich ascites carcinoma. Its mechanism of action involves the inhibition of tumor cell proliferation, making it a valuable compound for cancer research. Primocarcin is utilized in various studies aimed at understanding the efficacy of novel antitumor therapies and the biochemical pathways involved in cancer progression. -
Antibiotic
3''-Deamino-3''-hydroxykanamycin B is an antibiotic derived from the bacterium S. tenebrarius, specifically targeting bacterial ribosomes to inhibit protein synthesis. This compound exhibits notable effectiveness against Escherichia coli strains, including E. coli ATCC 25922 and E. coli CCARM 1A020, with minimum inhibitory concentration (MIC) values of 128 μg/mL. It is suitable for research applications involving antibiotic resistance and microbial susceptibility studies. -
Antibiotic
Eurocidin D is a cyclic peptide antibiotic that primarily targets and inhibits mast cell degranulation in rat models. This compound demonstrates significant anti-inflammatory properties, making it a valuable tool for studying allergic reactions and mast cell biology. Its unique mechanism of action positions it as a potential research candidate in understanding and treating conditions related to mast cell activation. -
Antibiotic
Lankacidinol is an antibiotic that exhibits significant biological activity against various pathogens. Its related metabolites, 2,18-seco-lankacidinol A and 2,18-seco-lankacidinol B, also demonstrate noteworthy medicinal properties. Notably, 2,18-seco-lankacidinol A has shown potent antitumor activity, making Lankacidinol a compound of interest for research in antibiotic and cancer therapeutics. -
Antibiotic
Oryzoxymycin is an aromatic derivative antibiotic targeting bacterial ribosomes to inhibit protein synthesis. This compound exhibits potent activity against Gram-negative bacteria, making it a valuable tool for studying antibiotic resistance mechanisms and bacterial infection pathways. It is applicable in research focused on microbial physiology and the development of new antibacterial agents. -
Antibiotic
BO-1165 is a potent antibiotic targeting Gram-negative bacteria with minimal efficacy against Gram-positive and anaerobic bacteria. It exhibits significant antibacterial activity against Pseudomonas aeruginosa, presenting a MIC50 of 3.12 mg/L, and against P. cepacia with a MIC50 of 1.56 mg/L. This compound is primarily utilized in research focused on combating infections caused by resistant Gram-negative pathogens. -
Antitumor Antibiotic
7-Hydroxyguanine is an antitumor antibiotic that primarily targets nucleic acid synthesis. It exhibits significant cytotoxicity against L1210 leukemia cells, effectively inhibiting their growth. This compound is utilized in cancer research to study mechanisms of action related to nucleobase analogs and their potential therapeutic applications.
