Catalog No.
Product Name
Application
Product Information
Citations
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Antioxidant/Antibacterial Agent
Eriodictyol 7, 3'-dimethyl ether is a flavonoid compound known for its antioxidant and antibacterial properties. Extracted from Berberis riparia, this compound demonstrates significant potential in mitigating oxidative stress and inhibiting bacterial growth. It is valuable for research applications focused on natural antioxidants and the development of antibacterial agents. -
Anti-Bacterial Agent
Saframycin Mx2 is an anti-bacterial agent that exhibits potent activity against both Gram-positive and Gram-negative bacteria. Its mechanism involves the inhibition of bacterial growth, making it valuable for research applications focused on antibiotic development and studies in microbial resistance. Saframycin Mx2 is suitable for use in various biological assays and exploration of antibacterial efficacy. -
Anti-Bacterial Agent
Peptaibolin is an anti-bacterial agent primarily targeting Gram-positive bacteria and yeast. It exhibits inhibitory activity against Staphylococcus subtilis ATCC 6633 and Candida albicans, with minimum inhibitory concentrations (MICs) of 100 μg/mL for both organisms. Due to its selective activity, Peptaibolin is useful for research applications aimed at understanding bacterial and fungal resistance mechanisms. -
Anti-Bacterial Agent
Chimeramycin A is an antibiotic compound that exhibits potent anti-Gram-positive bacterial and mycoplasma activity. It disrupts bacterial protein synthesis, making it an effective agent in combating infections caused by resistant strains. This compound is valuable for research applications focused on antibiotic resistance and the development of new antibacterial therapies. -
Anti-Bacterial Agent
Griseochelin is an anti-bacterial agent known for its robust activity against Gram-negative bacteria. Additionally, it demonstrates inhibitory effects on Coccidioides species, making it a valuable compound for research into fungal infections. Its unique properties make it suitable for investigations in both antimicrobial and antifungal applications. -
Bacterial Inhibitor
o-Cymen-5-ol acts as a broad-spectrum antimicrobial agent targeting various bacterial and fungal pathogens. It demonstrates effective minimum inhibitory concentrations (MICs) against organisms such as Streptococcus mutans and Candida albicans. Notably, o-Cymen-5-ol exhibits synergistic effects when combined with zinc, enhancing its antimicrobial activity against oral pathogens by inhibiting glycolysis. Studies indicate a more pronounced antibacterial effect in formulations such as toothpaste compared to placebo. This compound is valuable for research applications in microbiology and dental health. -
Anti-Bacterial Agent
Cephaibol D is an anti-bacterial agent derived from the Acremonium tubae strain DSM 12774. This compound exhibits weak antibacterial activity, making it a candidate for exploring mechanisms of antimicrobial resistance and the development of novel therapeutic agents. Its potential applications include studying bacterial metabolism and assessing the efficacy of various antimicrobial strategies. -
Antibacterial Agent
GDI-5755 is an antibacterial agent that targets and inhibits ClpP1P2, effectively reducing the growth of Mycobacterium tuberculosis and Mycobacterium bovis BCG. This compound is relevant for research applications focused on tuberculosis (TB) and provides a valuable tool for the study of mycobacterial infections. Its mechanism of action makes GDI-5755 a promising candidate for further investigation in the development of therapeutic strategies against TB. -
Anti-Bacterial Agent
Phencomycin is an anti-bacterial agent with a modest inhibitory effect on Gram-positive bacteria. Additionally, it targets the enzyme renin, affecting its activity with an IC50 of 440 μg/mL. This compound is useful in studies focused on bacterial resistance and enzyme modulation in physiological processes. -
Antibacterial Agent
Arizonin C1 is a microbial metabolite that functions as an antibacterial agent targeting Gram-positive bacteria. It exhibits significant antimicrobial activity, making it a valuable compound for research in the study of bacterial infections and the development of new antimicrobial therapies. Arizonin C1's unique properties contribute to its potential applications in antibiotic resistance studies and the discovery of novel antibacterial agents. -
Antibacterial Drug
LY 215891 is an antibacterial agent that demonstrates potent activity against both Gram-positive and Gram-negative bacteria. It achieves minimum inhibitory concentrations (MICs) of 0.015 μg/mL against Klebsiella pneumoniae X26 and 0.06 μg/mL against Escherichia coli EC14. This compound is valuable for research applications focusing on the development of novel antibacterial therapeutics and the study of bacterial resistance mechanisms. -
Anti-Bacterial Agent
Neoviridogrisein I is an anti-bacterial agent that selectively inhibits the growth of Gram-positive bacteria and mycoplasma. Its biological activity makes it a valuable tool in microbiological research and the study of bacterial resistance mechanisms. This compound can be employed in various experimental settings to further investigate bacterial pathogenesis and develop potential therapeutic strategies. -
Anti-Bacterial Agent
Monorden C is an anti-bacterial agent that effectively arrests the cell cycle of Jurkat cells in the G1 and G2/M phases. This compound demonstrates significant anti-Aspergillus niger activity, making it a valuable tool in research focused on fungal infections and cell cycle regulation. Its mechanisms of action provide insights into cellular responses to bacterial and fungal challenges, facilitating studies in both microbiology and cell biology. -
Anti-Bacterial Agent
Azicemicin B is an antibacterial agent that exhibits weak antimicrobial activity. Its low toxicity profile has been demonstrated in mouse models, making it a candidate for further evaluation in microbial research and potential therapeutic applications. This compound may be useful in studies exploring the mechanisms of bacterial resistance and the development of novel antibacterial strategies. -
Anti-Bacterial Agent
Emerimicin IV is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria. It interferes with bacterial protein synthesis, making it a valuable compound for research focused on developing new antimicrobial therapies. This reagent is particularly useful in studies investigating bacterial resistance and the mechanisms of action of antibiotics. -
Anti-Bacterial Agent
Lactonamycin is an anti-bacterial agent known for its potent activity against Gram-positive bacteria, specifically Staphylococcus, Streptococcus, Enterococcus, MRSA, and VRE, with minimum inhibitory concentrations (MIC) ranging from 0.39 to 0.78 μg/mL. Additionally, Lactonamycin demonstrates cytotoxic effects on various tumor cell lines, including L-1210, P388, S180, FS-3, Ehrlich, and B16-BL5, exhibiting IC50 values between 0.06 and 3.3 μg/mL. This compound is valuable for research focused on bacterial resistance and cancer therapeutics. -
Anti-Bacterial Agent
Nocathiacin II is a potent anti-bacterial agent primarily effective against Gram-positive bacteria. It demonstrates significant resistance to strains such as methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and multidrug-resistant Enterococcus faecalis (MREF). This compound is ideal for research applications focused on combating antibiotic resistance and developing effective antibacterial therapies. -
Bacterial Inhibitor
Strinoline is a bacterial inhibitor that targets and disrupts bacterial cell function. This compound exhibits significant antibacterial activity, making it a valuable tool for research in the field of microbiology. Strinoline can be utilized to study bacterial resistance mechanisms and the efficacy of antibiotic therapies. -
Anti-Bacterial Agent
Enaminomycin C is an anti-bacterial agent with a demonstrated ability to inhibit the growth of Gram-positive bacteria. Its activity profile shows weak effectiveness against Gram-negative bacteria, making it a candidate for further investigation in antibacterial research. Studies involving Enaminomycin C may contribute to the development of new therapeutic strategies against bacterial infections. -
Antibacterial Agent
Tacapenem, the active metabolite of CS-834, functions as a potent antibacterial agent. It demonstrates a broad spectrum of antibacterial activity against both gram-positive and gram-negative aerobes and anaerobes. Notably, Tacapenem exhibits strong bactericidal effects against Staphylococcus aureus and Escherichia coli, making it a valuable tool for research in bacterial infections and antibiotic resistance studies. -
Antibacterial Agent
Antibacterial agent 170 (compound 6b) is a potent antibacterial compound that targets the inhibition of biofilm formation in Pseudomonas aeruginosa PAO1. It demonstrates significant activity as a quorum sensing inhibitor through the las system, effectively disrupting bacterial communication and biofilm development. This agent is valuable for studies focused on microbial resistance and the mechanisms underlying bacterial pathogenicity. -
Antibacterial Agent
Colupulone is a β-acid resin derived from hops (Humulus lupulus) known for its antibacterial properties. It demonstrates significant activity against a range of bacteria as well as anti-larval effects on Culex mosquitoes. This compound is useful for investigations into infectious diseases and the development of novel antibacterial agents. -
Anti-Bacterial Agent
Kerriamycin C is an anti-bacterial agent targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it valuable for research in infectious disease and antimicrobial resistance. Additionally, Kerriamycin C has shown the ability to inhibit ascites cancer in experimental models, suggesting potential applications in cancer research. -
Antibacterial Agent
Anti-MRSA Agent 37 is an antibacterial agent specifically targeting methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 0.25-0.5 μg/mL. This compound effectively inhibits biofilm formation, disrupts cell wall integrity, compromises cell membrane stability, and induces oxidative stress in bacterial cells. It holds potential for research applications related to MRSA-associated diseases, particularly skin infections. -
Bacterial Metabolite
Steffimycin B is an anthracycline bacterial metabolite derived from Streptomyces, possessing a primary mechanism of DNA binding through preferential intercalation at cytosine and guanine-rich regions. It exhibits significant cytotoxicity against various cell lines, including MCF-7, KB, NCI-H187, and Vero cells, with IC50 values of 3.5, 6.75, 3.28, and 10.5 μM, respectively. Furthermore, Steffimycin B demonstrates potent antimicrobial activity against Mycobacterium tuberculosis (MIC=5.2 nM), Bacillus cereus (MIC=1.56 μg/mL), and Plasmodium falciparum (IC50=2.19 μM), making it a valuable compound for research in cancer and infectious diseases. -
Anti-Bacterial Agent
Lunatoic acid B is an anti-bacterial agent that exhibits significant bacterial inhibitory activity. Additionally, it demonstrates partial anti-mould properties, making it useful in studies exploring microbial resistance and infection control. This compound is applicable in various research contexts, including the development of novel antibacterial formulations and understanding mechanisms of microbial growth inhibition. -
Anti-Bacterial Agent
Juvenimicin A2 is an antibacterial agent that primarily targets a range of bacteria. It has demonstrated efficacy against Gram-positive bacteria and select strains of Gram-negative bacteria. This compound is utilized in research applications aimed at understanding bacterial resistance mechanisms and developing new antimicrobial therapies. -
Antibacterial Agent
Axinysone B functions as a potent antibacterial agent, isolated from the marine alga Laurencia similis. It exhibits significant activity against Staphylococcus species, making it a valuable compound for studies focused on antibacterial properties and microbial resistance. This reagent is suitable for research applications aimed at understanding bacterial infections and exploring novel antibacterial treatments. -
Antibacterial Agent
Arizonin B2 is a microbial metabolite that functions as an antibacterial agent, primarily targeting Gram-positive bacteria. Its effectiveness against these pathogens makes it a valuable tool for research into antibacterial treatments and mechanisms of resistance. A potential candidate for studies involving the development of new antibiotics, Arizonin B2 contributes to the understanding of microbial interactions and infections. -
Antibacterial Peptoid
CHIR-29498 is an antibacterial peptoid that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound is particularly useful in the investigation of pathogenic strains such as Staphylococcus aureus. CHIR-29498 serves as a valuable tool for research focused on bacterial infections and the development of novel antimicrobial therapies. -
Anti-Bacterial Agent
Olivomycin A is an antibiotic with potent activity against Gram-positive bacteria, demonstrating significant effectiveness in inhibiting bacterial growth. Its mechanism of action involves interference with nucleic acid synthesis, making it a valuable tool in microbiological research. Olivomycin A is particularly useful for studying bacterial resistance mechanisms and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Rhodomycin B is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity while demonstrating a weaker effect against Gram-negative bacteria and fungi. Rhodomycin B serves as a valuable reagent in research focusing on bacterial infections and antibiotic resistance mechanisms. -
Anti-Bacterial Agent
Midecamycin A4 is a macrolide antibiotic primarily targeting Gram-positive bacteria, exhibiting potent antibacterial activity. It demonstrates limited effectiveness against Gram-negative bacteria, mycobacteria, and fungi. This compound is valuable in research focused on antibiotic resistance and the development of novel antimicrobial agents. -
Anti-Bacterial Agent
Formadicin B is an anti-bacterial agent that exhibits potent activity against various strains of Pseudomonas, Proteobacteria, and alkaline-producing bacilli. This compound is valuable in research focused on bacterial infections and the development of new antimicrobial therapies. Its efficacy against multi-drug resistant bacteria makes it a significant candidate for further investigation in the field of microbiology. -
Antibacterial Agent
Broquinaldol is a brominated quinoline that serves as a potent antibacterial agent specifically effective against Staphylococcus species. In addition to its antimicrobial properties, Broquinaldol acts as a Mn(II) ionophore, facilitating the synthesis of metalloantibiotics. This compound is valuable in research focused on developing novel antibacterial therapies and understanding metal ion interactions in biological systems. -
Antibacterial Agent
Trospectomycin is a broad-spectrum antibacterial agent that targets bacterial protein synthesis by inhibiting ribosomal function. This compound is especially relevant in the study of resistant bacterial strains and can be utilized in research focusing on antibiotic efficacy and mechanisms of resistance. Its structural similarity to Spectinomycin allows for exploration of its unique pharmacological properties and potential therapeutic applications in infectious disease research. -
Anti-Bacterial Agent
3-Ethyl-1,3-dihydro-3-methoxy-2H-indol-2-one targets bacterial pathogens with demonstrated antimicrobial activity against both Gram-positive and Gram-negative bacteria. This indole derivative is valuable for research focused on the development of new antibacterial agents and exploring mechanisms of bacterial resistance. Its broad-spectrum properties make it a significant candidate for further investigation in microbial studies. -
Bacterial
Dealanylalahopcin is an antimicrobial agent primarily targeting bacterial pathogens. Isolated from Streptomyces leucoderma subsp. ochraceus, this compound demonstrates weak antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it exhibits moderate inhibition of collagen prolyl hydroxylase, making it a potential candidate for studies in collagen-related research and antimicrobial applications. -
Antibacterial Agent
SC 44914 is a quinoxaline derivative primarily known for its antibacterial properties. It exhibits significant activity against a range of pathogenic bacteria, including Campylobacter jejuni, Campylobacter coli, and Clostridium difficile. This compound is valuable for research applications focused on antibiotic development and the study of bacterial resistance mechanisms. -
Anti-Bacterial Agent
Isohematinic acid is a compound with established activity as an anti-bacterial agent. It exhibits weak inhibition against anaerobic bacteria, making it a valuable tool for researching microbial infections. Its functionality supports studies focused on understanding bacterial resistance mechanisms and developing novel therapeutic strategies. -
Bacterial Metabolite
Neoaureothin is a bacterial metabolite derived from Streptomyces that functions as an androgen receptor (AR) antagonist. It effectively inhibits the binding of dihydrotestosterone (DHT) to ARs, demonstrating an IC50 of 13 μM, and significantly reduces DHT-induced prostate-specific antigen expression in LNCaP cells with an IC50 of 1.75 nM. Additionally, Neoaureothin exhibits cytotoxic effects on A549, HCT116, and HepG2 cell lines with IC50 values of 34.3, 47, and 37.2 μg/mL, respectively. It also displays potent nematocidal activity against B. xylophilus, with an LC50 of 0.84 μg/mL, and enhances the survival of P. densiflora trees infected with this nematode. -
Antibacterial Agent
A-867191 hydrochloride is a selective inhibitor of DNA gyrase, acting primarily as an antibacterial agent. This compound exhibits potent antibacterial activity, making it a valuable tool in the study of bacterial infections. A-867191 hydrochloride is suitable for various research applications focused on combating antibiotic resistance and understanding bacterial DNA replication mechanisms. -
Anti-Bacterial Agent
Cissetin is an anti-bacterial agent that selectively targets Gram-positive bacteria, demonstrating significant activity against various drug-resistant strains. This compound is valuable for research applications focused on exploring mechanisms of antibiotic resistance and developing novel antibacterial therapies. Its efficacy against resistant pathogens makes it an important candidate for further study in infectious disease research. -
Antibacterial Agent
Antibacterial agent 327 is a potent inhibitor of Staphylococcus aureus DNA gyrase, demonstrating an IC50 of 0.28 μM against supercoiling activity. It additionally inhibits ATPase activities of both DNA gyrase and Topoisomerase IV, with IC50 values of 0.43 μM and 0.73 μM, respectively, while also affecting Topoisomerase IV decatenation activity (IC50: 2.31 μM). This compound effectively inhibits Clostridioides difficile and methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 0.78 μg/mL for both, and shows an MIC50 of 0.78 μg/mL against Escherichia coli. Antibacterial agent 327 is valuable for research focused on bacterial resistance and DNA topology. -
Antibacterial Agent
2,2',4'-Trichloroacetophenone functions as an antibacterial agent targeting various bacterial pathogens. It demonstrates significant antibacterial activity against Xanthomonas oryzae pv. oryzae and Xanthomonas axonopodis pv. citri, with effective concentrations (EC50) of 0.54 mg/L and 2.02 mg/L, respectively. This compound is suitable for research applications focused on understanding antibacterial properties and mechanisms. -
Anti-Bacterial Agent
Chloronectrin functions as an anti-bacterial agent with a primary mechanism targeting Gram-positive bacteria. It exhibits significant inhibitory activity against various strains, making it valuable for research in antibacterial efficacy and the development of new therapeutic agents. This compound is particularly useful for studies focused on combating Gram-positive bacterial infections. -
Antibacterial Agent
10-Methyldodec-2-en-4-olide is an antibacterial agent derived from Streptomyces. It exhibits significant antibacterial activity against a range of pathogens, including Botrytis cinerea, Saccharomyces cerevisiae, Staphylococcus aureus, and Micrococcus luteus. This compound may be useful in various research applications exploring antimicrobial efficacy and mechanisms of resistance. -
Anti-Bacterial Agent
4-Deoxybostrycin is a potent anti-bacterial agent targeting Bacillus subtilis. This compound exhibits significant antibacterial activity, making it a valuable tool for studying bacterial infections and developing new antimicrobial therapies. Its efficacy against Gram-positive bacteria highlights its potential applications in microbiological research and drug discovery. -
Anti-Bacterial Agent
Saframycin D is an anti-bacterial agent that exhibits effective activity against Gram-positive bacteria. Additionally, it shows limited activity against mycobacteria. This compound is valuable for research applications focused on bacterial infections and the study of bacterial resistance mechanisms. -
Bacterial Agonist
Rhizopterin is a bacterial agonist that plays a critical role in promoting plant growth by facilitating the synthesis of rhizobactin in folate-deficient synthetic media. Its unique mechanism enhances nutrient availability and supports the growth of beneficial rhizobacteria. This reagent is valuable for research applications in microbiology, plant biology, and the study of plant-microbe interactions.
