Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
LB 10517 (sodium) is a cephalosporin antibiotic known for its broad-spectrum antibacterial activity. It effectively targets both Gram-positive and Gram-negative bacteria, including notable pathogens such as Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus. This compound is valuable for research applications focused on bacterial infections and antibiotic resistance mechanisms. -
Anti-Bacterial Agent
9-Hydroxycrisamicin, an anti-bacterial agent, exhibits weak activity against Gram-positive bacteria with a minimum inhibitory concentration (MIC) ranging from 6.25 to 25 μg/mL. Additionally, 9-Hydroxycrisamicin demonstrates significant growth inhibition in various human tumor cell lines, making it a valuable compound for research in both antibacterial and oncological studies. -
Anti-Bacterial Agent
Kigamicin A is an anti-bacterial agent with demonstrated efficacy against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Its minimum inhibitory concentrations (MICs) range from 0.025 to 0.78 μg/mL, indicating potent antibacterial activity. This compound is valuable in research focused on combating antibiotic-resistant bacterial infections and exploring new therapeutic options. -
Antibacterial Agent
PYO12 is a selective antibacterial compound targeting Gram-positive bacteria. It demonstrates potent activity against S. aureus, B. subtilis, S. pneumoniae, and MRSA, with minimum inhibitory concentrations (MIC) of 1 μg/mL for the first three and 4 μg/mL for MRSA. PYO12 enhances bacterial membrane permeability and upregulates stress-related genes by potentially binding to the C55-PP moiety of lipid II. Its concentration-dependent bactericidal effect, coupled with low toxicity to mammalian cells and lack of hemolytic activity, positions PYO12 as a promising candidate for the development of novel antibiotics focused on bacterial cell wall synthesis. -
Antibacterial Agent
ML370 is an antibacterial agent that functions by inhibiting the activity of the Vibrio cholerae LuxO kinase. This inhibition disrupts bacterial signaling, thereby impeding the growth and virulence of cholera pathogens. ML370 is suitable for research applications focused on infectious diseases, particularly in studies related to cholera and other Vibrio species. -
Anti-Bacterial Agent
Emerimicin III is an anti-bacterial agent primarily targeted against Gram-positive bacteria. This compound exhibits potent inhibitory effects, making it a valuable tool in research focused on bacterial infections and resistance mechanisms. Its unique structure and activity profile facilitate studies into novel therapeutic approaches for combatting Gram-positive pathogens. -
Anti-Bacterial Agent
Hazimycin 5 is an anti-bacterial agent with demonstrated activity against Gram-negative bacteria, as well as select yeast and skin fungi. This compound is useful in research applications focused on identifying and characterizing the mechanisms of bacterial resistance and the effects of antimicrobial agents. Its weak activity profile makes it particularly relevant in studies exploring the efficacy of combination therapies or the development of new antimicrobial compounds. -
Antibacterial Agent
Antibacterial agent 311 targets bacterial infections through its potent antibacterial activity. It demonstrates efficacy against clinically relevant pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and resistant strains such as E. CTXM1 and E. NDM1, with minimal inhibitory concentrations (MICs) ranging from 0.7 to 1 mg/mL. This compound is valuable for research applications focused on antimicrobial resistance and the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Curvulic acid is an anti-bacterial agent that exhibits modest inhibitory activity against both Gram-positive and Gram-negative bacteria. Its biological activity makes it a potential candidate for research in antimicrobial studies and the development of new antibacterial therapies. This compound can be utilized in investigations focusing on bacterial resistance mechanisms and the evaluation of novel antibacterial agents. -
Bacterial Inhibitor
WQ3810 is a fluoroquinolone antibiotic that acts by inhibiting bacterial DNA gyrase and topoisomerase IV, critical enzymes for DNA replication and transcription. This compound exhibits potent antibacterial activity against a range of gram-positive and gram-negative bacteria. WQ3810 is valuable for research applications focused on studying bacterial infections and developing effective antimicrobial therapies. -
Bacterial Inhibitor
Vebufloxacin is a synthetic antibacterial agent that targets bacterial DNA gyrase, leading to the inhibition of bacterial DNA replication and transcription. It demonstrates potent activity against both gram-positive and gram-negative bacteria, making it a valuable tool in studying bacterial infections and resistance mechanisms. Research applications include evaluating the efficacy of antibacterial treatments and understanding the molecular basis of bacterial survival. -
Bacterial Inhibitor
BO3482 is a bacterial inhibitor that exhibits antimicrobial activity against methicillin-resistant Staphylococci (MRS). It demonstrates a minimum inhibitory concentration (MIC90) of 6.25 mg/mL, effectively halting bacterial growth. This compound is valuable for research applications focused on antibiotic resistance and the development of new antibacterial agents. -
Bacterial Inhibitor
A7132 is a potent antibacterial agent that targets bacterial infections. This compound exhibits broad-spectrum antibacterial activity, making it a valuable tool for research applications in antimicrobial studies and the development of new therapies against bacterial resistance. A7132 is suitable for evaluating the efficacy of antibacterial compounds in various biological assays. -
Antibacterial Agent
HSGN-218 is an antibacterial agent that demonstrates potent efficacy against various strains of Clostridium difficile, exhibiting minimum inhibitory concentration (MIC) values between 0.007 μM and 0.07 μM. Despite its low permeability across Caco-2 cells, HSGN-218 is a valuable tool for investigating bacterial growth inhibition and exploring therapeutic options for C. difficile infections in research applications. -
Bacterial Inhibitor
Pyrroxamycin is a novel antibiotic with a primary mechanism targeting Gram-positive bacteria and dermatophytes. Derived from the fermentation of Streptomyces, it exhibits potent antibacterial activity. This compound has potential applications in pharmaceutical research for the development of new antimicrobials, particularly against resistant bacterial strains. Detailed analysis of its chemical structure was performed using X-ray crystallography and 13C NMR spectroscopy, elucidating its physicochemical properties and enhancing its utility in microbiological studies. -
Antibacterial Agent
Antibacterial Agent 39 is a potent antibacterial compound that demonstrates synergistic effects by significantly lowering the minimum inhibitory concentration (MIC) of Ceftazidime. This compound exhibits strong antibacterial activity against various Gram-negative bacteria, making it a valuable tool for research focused on combating antibiotic resistance and enhancing the efficacy of existing antibiotics. Its application in microbiological studies can provide insights into the mechanisms of action and interactions between different antibacterial agents. -
Anti-Bacterial Agent
Juncuenin D is an anti-bacterial agent known for its ability to induce caspase-3-mediated cytotoxicity in HT22 cells. This compound exhibits significant anti-bacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains. Juncuenin D is derived from Juncus effusus and serves as a valuable tool for research in infectious disease and cell death mechanisms. -
Antibacterial Peptide
Latarcin 2a is a linear cationic antibacterial peptide derived from the venom of the spider Lachesana tarabaevi, exhibiting broad-spectrum antibacterial activity. It demonstrates a minimum inhibitory concentration (MIC) of 0.5 μM against both Bacillus subtilis and Escherichia coli. This peptide is primarily utilized in research related to infectious diseases and the development of novel antimicrobial agents. -
Antibacterial Agent
Antibacterial Agent 60 is a potent antibacterial compound that enhances the efficacy of Ceftazidime by significantly reducing its minimum inhibitory concentration (MIC). This agent exhibits strong antibacterial activity, making it particularly useful in overcoming bacterial resistance. It can be employed in various research applications focused on developing improved antimicrobial therapies and optimizing existing antibiotics against resistant strains. -
Bacterial Inhibitor
β-Lactamase-IN-6 is a potent inhibitor of β-Lactamase enzymes, which play a crucial role in bacterial resistance to β-lactam antibiotics. This compound demonstrates significant antibacterial activity by preventing the enzymatic breakdown of β-lactam antibiotics, thereby enhancing their effectiveness against resistant bacterial strains. β-Lactamase-IN-6 serves as a valuable tool in microbiological research and antibiotic development, providing insights into combating bacterial infections and resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 51 primarily targets bacterial cell growth and division. It exhibits minimum inhibitory concentration (MIC) values of 4 mcg/mL against E. coli NCTC 13351 and 8 mcg/mL against both E. coli strains M 50 and 7 MP. This compound is valuable for research applications focused on bacterial resistance and the development of new antibacterial therapies. -
Bacterial Inhibitor
(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that effectively disrupts DNA supercoiling, exhibiting an IC50 of 3.3 µM. This compound demonstrates significant antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Salmonella enterica, with minimum inhibitory concentrations ranging from 10 to 80 µM. Notably, (R)-Gyramide A hydrochloride does not inhibit topoisomerase IV, making it a valuable tool for studying bacterial mechanisms and antibiotic resistance. -
Antibacterial Agent
Heronapyrrole B is a Gram-positive-selective antibacterial agent with an IC50 range of 0.6-1.1 μM against Staphylococcus aureus ATCC9144. This compound demonstrates potent antibacterial activity, making it a valuable tool in the study of bacterial infections. Its specific mechanism of action and efficacy position it for potential applications in antibiotic research and development. -
Antibacterial Agent
Antibacterial Agent 192 is an antibacterial compound that targets and disrupts iron homeostasis in Escherichia coli. This mechanism leads to impaired bacterial growth and viability, making it a valuable tool for studying bacterial metabolism and resistance mechanisms. Its applications include research in antibiotic development and the investigation of bacterial iron regulation processes. -
Antimycobacterial Agent
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound with noted antimycobacterial activity. Isolated from Ganoderma lucidum, this compound demonstrates effectiveness against mycobacterial infections, making it a valuable resource in antibacterial research. Its unique structure and biological properties render it a promising candidate for further investigation in the development of antimycobacterial therapies. -
Antibacterial Agent
Ro 24-4383 is a carbamate-linked compound that exhibits antibacterial activity through a dual mechanism of action. It effectively targets bacterial cell processes, making it a valuable tool in antibacterial research. This compound is useful for studies related to bacterial resistance and the development of new antibacterial therapies. -
Bacterial
B1912 is an antibacterial compound that demonstrates significant efficacy against various bacterial strains. Its primary mechanism involves disrupting bacterial cell wall synthesis, leading to cell lysis and death. This reagent is valuable for research applications focused on developing new antibacterial therapies and studying bacterial resistance mechanisms. -
Antibacterial Agent
DPI-2016 is an antibacterial agent that demonstrates potent bactericidal activity, with minimum inhibitory concentrations (MIC) ranging from 0.25 to 8 μg/mL across various bacterial strains. This compound exhibits enhanced effectiveness compared to standard treatments such as aztreonam, which has MIC values between 16 and greater than 64 μg/mL. DPI-2016 is suitable for research applications aimed at investigating bacterial resistance and efficacy in therapeutic interventions. -
Antibacterial Agent
Bauer-7-ene-3β,16α-diol is a triterpenoid with demonstrated antibacterial properties, primarily targeting bacterial strains such as E. coli. Isolated from the dried flower buds of Tussilago farfara L. or Petasites tricholobus, it exhibits medium antibacterial activity, making it a valuable reagent for research in natural product pharmacology and the development of antimicrobial agents. Its structural features and potency may facilitate investigations into the mechanisms of bacterial resistance and alternative therapeutic strategies. -
Antibacterial Agent
Antibacterial agent 99 (compound 7b) is a potent antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant antibacterial and antifungal activity, making it suitable for various microbiological research applications. Additionally, antibacterial agent 99 demonstrates no hemolytic activity, indicating a favorable safety profile for potential therapeutic use. -
Bacterial Inhibitor
Acrisorcin is a topical anti-infective compound that functions primarily as a bacterial inhibitor. It exhibits potent fungicidal properties, making it valuable for research into antifungal therapies and the understanding of bacterial resistance mechanisms. Its efficacy in mitigating fungal infections supports its application in various microbiological studies and therapeutic evaluations. -
Antibacterial Agent
Antibacterial Agent 45 is an effective antibacterial compound that enhances the efficacy of Ceftazidime by significantly lowering its minimum inhibitory concentration (MIC) value. This agent demonstrates potent antibacterial activity, making it a valuable tool for researchers studying bacterial resistance and developing novel antimicrobial therapies. Its application in combinatorial therapies holds promise for advancing understanding of bacterial pathogenesis and treatment strategies. -
Antibacterial Agent
Prenylterphenyllin is an antibacterial agent derived from the marine fungus Aspergillus candidus IF10. It exhibits significant cytotoxic activity against KB3-1 cells, with an IC50 value of 8.5 mg/mL. Additionally, Prenylterphenyllin demonstrates antibacterial properties against Xanthomonas oryzae and Erwinia amylovora, both exhibiting minimum inhibitory concentrations (MICs) of 20 μg/mL. This compound is useful for research in antimicrobial drug development and the study of marine-derived natural products. -
Antibacterial agent
Antibacterial Agent 245 (Dc-2) is an effective antibacterial compound targeting plant pathogenic fungi and bacteria. It demonstrates a potent activity with an EC50 value of 1.29 μg/mL against Botrytis cinerea. This reagent is suitable for research applications in plant pathology and the development of biocontrol agents. -
Anti-Bacterial Agent
Galacardin A is an anti-bacterial agent that primarily exhibits activity against Gram-positive bacteria. Its mechanism of action involves disrupting bacterial cell wall synthesis, resulting in inhibition of bacterial growth. Galacardin A is suitable for research applications focused on developing new antibacterial therapies and studying microbial resistance. -
Anti-Bacterial Agent
Polymyxin S1 is an anti-bacterial agent derived from Bacillus polymyxa RS-6, known for its potent activity against Gram-negative bacteria. This compound disrupts bacterial cell membrane integrity, leading to cell lysis and death. Polymyxin S1 is primarily utilized in research focusing on antibiotic action mechanisms and the development of new antimicrobial strategies. It offers valuable insights for studies targeting drug resistance and the efficacy of antibacterial compounds. -
Anti-Bacterial Agent
Pacidamycin 5 is an anti-bacterial agent that exhibits inhibitory activity against Pseudomonas aeruginosa. Additionally, it demonstrates effectiveness against various strains of bacteria, including Staphylococcus aureus and Escherichia coli. This compound is valuable for research applications focused on the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Cephamycin A is an antibiotic that primarily targets bacterial cell wall synthesis. It exhibits moderate antibacterial activity against a range of Gram-positive and Gram-negative bacteria. This compound is useful in research applications focused on developing novel antibacterial agents and studying bacterial resistance mechanisms. -
Anti-Bacterial Agent
Fluoropolyoxin M is an anti-bacterial agent that exhibits inhibitory activity against Escherichia coli and Streptococcus faecalis. This compound is primarily utilized in research focused on bacterial infections and antibiotic resistance mechanisms. Its effectiveness against these pathogens makes it a valuable tool for studies in microbiology and pharmacology. -
Bacterial Inhibitor
CID21480113 is an inhibitor targeting bacterial pathways, specifically effective against dapsone-resistant strains of leprosy. This compound demonstrates significant antibacterial activity, making it a valuable tool for research in microbial resistance and infectious disease studies. Its ability to combat resistant bacteria positions CID21480113 as a relevant reagent for investigations into alternative therapies for leprosy. -
Anti-Bacterial Agent
Cyclacidin is an anti-bacterial agent targeting Gram-positive bacteria, including Bacillus subtilis and Gambusia occidentalis. It exhibits significant antimicrobial activity and demonstrates an inhibitory effect on sarcoma 180 cells. This compound is valuable for research applications focused on bacterial infections and cancer therapeutic strategies. -
Anti-Bacterial Agent
1-Hydroxycrisamicin A is an effective anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits potent activity with a minimum inhibitory concentration (MIC) ranging from 0.78 to 3.12 μg/mL. This compound holds significant potential for research applications in the study of bacterial infections and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Pacidamycin 2 is an antibacterial agent that primarily targets and inhibits Pseudomonas aeruginosa. It also demonstrates activity against various strains of bacteria, including Suppurative Staphylococcus and Escherichia coli. This compound is useful in antibacterial research and investigation of microbial resistance. -
Antibacterial Peptide
CP7-FP13-2 is an antibacterial peptide that targets virulence factors in bacteria. It effectively inhibits the formation of biofilms in Staphylococcus aureus, demonstrating potent antibacterial activity in in vivo mouse models. This compound is valuable for research applications focusing on microbial resistance and the development of alternative therapeutic strategies against bacterial infections. -
Antibacterial Agent
γ-Rubromycin is a natural compound derived from Streptomyces, primarily acting as an antibacterial agent. It exhibits significant antibacterial activity, making it a valuable tool for exploring microbial resistance mechanisms and developing new therapeutic strategies against bacterial infections. This reagent is suitable for research applications focused on antimicrobial efficacy and the biochemical pathways associated with bacterial pathogens. -
Antibacterial Agent
Beauvericin A is a cyclodepsipeptide with potent antibacterial activity, primarily targeting Mycobacterium tuberculosis and Plasmodium falciparum. It exhibits a minimum inhibitory concentration (MIC) of 25 μg/mL against M. tuberculosis and an IC50 of 12 μg/mL against P. falciparum, demonstrating its potential as a valuable agent in infectious disease research. Additionally, Beauvericin A shows toxicity to brine shrimp, indicating its bioactive properties that can be explored in various biological assays. -
Antibacterial Agent
Norfloxacin succinil is a quinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV, leading to the inhibition of DNA replication and repair. This compound exhibits effective antimicrobial activity against a range of Gram-negative and Gram-positive bacteria. It is primarily utilized in research related to infectious diseases, particularly in the study of urinary tract infections. -
Antibacterial Agent
Antibacterial Agent 281 specifically targets the growth of Streptococcus pyogenes (GAS) through bacteriostatic inhibition. This compound binds to the ligand binding pocket of SPs0871, effectively competing with the native ligand. Antibacterial Agent 281 demonstrates concentration-dependent inhibition of S. pyogenes growth, making it a valuable tool for research into antibacterial mechanisms and therapeutic development. -
Anti-Bacterial Agent
Kibdelin B is an anti-bacterial agent that targets Gram-positive bacteria, exhibiting significant activity against Staphylococcus aureus, including methicillin-resistant strains (MRSA). Its mechanism of action parallels that of Vancomycin, making it a valuable compound for research applications in developing new therapeutic strategies against resistant bacterial infections. -
Anti-Bacterial Agent
Amidinomycin is an antibacterial agent that primarily targets Gram-positive bacteria. It exhibits moderate antibacterial activity, making it useful for studying bacterial resistance mechanisms and evaluating potential therapeutic strategies. Its efficacy in inhibiting Gram-positive strains positions it as a valuable reagent for microbiological research and drug development.
