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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Ceftiofur is a cell wall synthesis inhibitor targeting bacterial penicillin-binding proteins (PBPs). It demonstrates bactericidal activity by interfering with the peptidoglycan synthesis in bacterial cell walls, resulting in cell lysis. Additionally, Ceftiofur exhibits anti-inflammatory properties by inhibiting the activation of NF-κB and MAPKs, which decreases the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. This makes Ceftiofur a valuable reagent in research investigating bacterial infections and inflammation processes. -
Bacterial Inhibitor
Aeroplysinin 1 is a secondary metabolite with a primary target as a bacterial inhibitor. It exhibits significant antibiotic activity against Gram-positive bacteria and demonstrates antiviral efficacy against HIV-1, with an IC50 of 14.6 μM. Additionally, Aeroplysinin 1 possesses anti-inflammatory, anti-angiogenic, and anti-tumor properties, and has been shown to induce apoptosis in endothelial cells. This compound is valuable for research applications in microbiology, virology, and cancer studies. -
Bacterial/Fungal Inhibitor, Preservative Agent
Methylisothiazolinone hydrochloride is a bacterial and fungal inhibitor, primarily functioning as a preservative agent. It activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Research indicates that it may promote the development of atopic dermatitis in murine models by disrupting Th2/Th17 immune responses. Additionally, Methylisothiazolinone hydrochloride has been shown to cause mitochondrial damage in the endothelium of rat cerebral blood vessels, highlighting its cellular impact. -
Bacterial Inhibitor
K-252c is a staurosporine analog that selectively inhibits protein kinase C (PKC), exhibiting an IC50 value of 2.45 µM. This compound is known for its ability to induce apoptosis in human chronic myelogenous leukemia cells, making it a valuable tool in cancer research. Additionally, K-252c demonstrates inhibitory effects on β-lactamase, chymotrypsin, and malate dehydrogenase, further expanding its utility in studying bacterial resistance and enzyme activity. -
Bacterial Agent And Polyamine Transport System Inhibitor
AMXT-1501 is an antibacterial agent and polyamine transport system inhibitor that targets membrane phospholipids. It exhibits significant antibacterial activity against a range of multidrug-resistant Gram-positive and Gram-negative bacteria, specifically inhibiting capsular biosynthesis in Streptococcus pneumoniae. Additionally, AMXT-1501 interferes with ornithine decarboxylase and polyamine pathways, leading to the inhibition of neuroblastoma cell proliferation. Research applications include studies on multidrug-resistant bacterial infections, pneumococcal infections, and neuroblastoma therapeutics. -
Bacterial Inhibitor
Vasicine, a quinazoline alkaloid derived from Justicia adhatoda, primarily targets bacterial strains as an inhibitor. This compound is known to activate the PI3K/Akt signaling pathway and demonstrates significant antioxidant and anti-inflammatory activities. Its unique biological profile makes Vasicine valuable for research in microbial resistance and inflammation-related studies. -
Bacterial Inhibitor
Vasicine hydrochloride, a quinazoline alkaloid derived from Justicia adhatoda, acts primarily as a bacterial inhibitor. It activates the PI3K/Akt signaling pathway and demonstrates significant antioxidant and anti-inflammatory properties. This compound is valuable for research involving antimicrobial activity and cellular signaling pathways, making it a useful tool for studies in infectious disease and inflammation. -
Bacterial Inhibitor
Bavachalcone is a bacterial inhibitor known for its multifaceted biological activities. It induces apoptosis and enhances autophagy in HepG2 cancer cells, contributing to its anticancer potential. Additionally, Bavachalcone demonstrates anti-neuroinflammatory and antidepressant effects through modulation of the NF-κB pathway. It also inhibits osteoclast differentiation by interfering with ERK and Akt signaling pathways, as well as the expression of c-Fos and NFATc1, and shows a significant inhibitory effect on BACE-1 activity in vitro. -
Bacterial Inhibitor
Lysozyme, also known as Muramidase, is a conserved antimicrobial protein that targets bacterial cell wall peptidoglycan (PG). It exerts a bactericidal effect by hydrolyzing PG, thereby limiting bacterial growth on mucosal surfaces and controlling potential pathogens while preventing dysbiosis through microbiota regulation. Additionally, extracellular lysozyme degrades polymeric PG into soluble fragments, activating NOD receptors in mucosal epithelial cells and stimulating the secretion of chemokines and activating factors by neutrophils and macrophages. This makes lysozyme a valuable reagent for studies involving antimicrobial activity, immune response, and microbiome research. -
Bacterial Inhibitor
Ciclopirox olamine is a synthetic antifungal agent primarily targeting various fungal pathogens. It exhibits a broad spectrum of activity against dermatophytes, yeasts, molds, and multiple Gram-positive and Gram-negative bacteria. In addition to its antibacterial properties, Ciclopirox olamine has demonstrated anticancer and anti-inflammatory effects, making it a valuable reagent for research in superficial mycoses, cancer biology, and inflammation studies. -
Bacterial Inhibitor
Bafilomycin B1 is a macrolide antibiotic that targets vacuolar H+-ATPases (V-ATPases). It exhibits neuroprotective properties against Chloroquine-induced cell death and can significantly inhibit the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL). Bafilomycin B1 is valuable for research focused on bacterial inhibition and studying lipid metabolism and cellular stress responses. -
Bacterial Inhibitor
Robinetin, a naturally occurring flavonoid, primarily acts as a bacterial inhibitor. This compound exhibits diverse biological activities, including antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant properties. Additionally, Robinetin has demonstrated the ability to inhibit lipid peroxidation and protein glycosylation, making it valuable for various research applications in microbiology and biochemistry. -
Bacterial Inhibitor
Tricyclazole is a pentaketone compound that acts as a bacterial inhibitor primarily by disrupting melanin biosynthesis in fungi. This unique fungicide is effective in controlling rice blast disease by altering the structure and function of fungal cell walls, thereby reducing pathogenicity and penetration. Tricyclazole’s mechanism of action also highlights its potential for studying fungal biology and the effects of melanin on fungal virulence. -
Bacterial/Fungal Inhibitor
2-Methoxybenzaldehyde, also known as o-Anisaldehyde, serves as a bacterial and fungal inhibitor, with a BA50 value of 0.19 against Salmonella. This compound is utilized in the investigation of bacterial and fungal infectious diseases, providing insights into their mechanisms and potential therapeutics. Its effectiveness in hindering microbial growth makes it a valuable reagent for microbiological research. -
Bacterial Inhibitor
Enoxacin is a fluoroquinolone antibacterial that primarily targets bacterial DNA gyrase and topoisomerase IV, with reported IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. It exhibits strong inhibitory activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin acts as a miRNA processing activator, facilitating siRNA-mediated mRNA degradation and promoting the biogenesis of endogenous miRNAs. Notably, Enoxacin serves as a cancer-specific growth inhibitor through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing, making it valuable for research in bacterial inhibition and cancer biology. -
Bacterial Inhibitor
Roxithromycin is a semi-synthetic macrolide antibiotic that exerts its antibacterial effects by inhibiting protein biosynthesis at the elongation step through binding to the 50S subunit of the bacterial ribosome. This compound demonstrates broad biological activity, including antimicrobial, antiproliferative, and anti-inflammatory properties. Additionally, Roxithromycin has been shown to inhibit tumor vasculature and alleviate lung injury, making it a valuable reagent for research applications in infectious disease, cancer therapy, and respiratory health. -
Bacterial Inhibitor
Benzoic acid is an aromatic carboxylic acid that functions as a bacterial inhibitor. It demonstrates significant antimicrobial activity by inhibiting the growth of bacteria and fungi, making it an effective preservative. Benzoic acid is widely utilized in food, beverages, cosmetics, and various research applications to study microbial growth inhibition and preservation techniques. -
Bacterial Inhibitor
Tilmicosin is a macrolide antibiotic and calcium channel antagonist that targets the bacterial ribosome's 50S subunit, effectively inhibiting protein synthesis. It possesses significant antimicrobial activity and is primarily utilized in treating respiratory diseases in livestock, including cattle, sheep, and pigs. Additionally, Tilmicosin exhibits immunomodulatory and anti-inflammatory properties, making it a valuable reagent in veterinary medicine research. -
Bacterial Inhibitor
Sodium citrate dihydrate is a bacterial inhibitor that acts by disrupting cellular processes in bacteria. This compound exhibits antibacterial, anti-tumor, and antioxidant activities, demonstrating potential in both microbial and cancer research applications. It can be utilized as a cosolvent or buffer in various biochemical assays, facilitating enhanced stability and solubility of target compounds. -
Bacterial/Fungal Inhibitor
Pyruvic acid semicarbazone is a bacterial and fungal inhibitor. This compound demonstrates significant biological activity against various microbial strains, making it a valuable tool for investigating anti-infective agents. Additionally, pyruvic acid semicarbazone has potential applications in cancer research and plant growth regulation studies. -
Bacterial Inhibitor
X-Neu5Ac sodium is a neuraminidase substrate that facilitates the chromogenic assay of neuraminidase activity in bacterial expression systems. This compound has a Km value of 0.89 mM for neuraminidase, making it an effective tool for studying neuraminidase function and inhibition. Its use in research applications provides insights into bacterial mechanisms and potential therapeutic targets for bacterial infections. -
Bacterial Inhibitor
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic that primarily targets bacterial growth by inhibiting dihydropteroate synthase and disrupting folate synthesis. This compound exhibits significant antibacterial activity and is primarily utilized in research applications focused on understanding bacterial infections and exploring antibiotic resistance mechanisms. Suitable for studies related to dermatological conditions, it aids in exploring therapeutic strategies for diseases like dermatitis herpetiformis. -
Bacterial Inhibitor
Enoxacin hydrate, a fluoroquinolone antibiotic, targets bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication with IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. This compound exhibits significant antibacterial activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin hydrate functions as an activator of miRNA processing, facilitating siRNA-mediated mRNA degradation and enhancing the biogenesis of endogenous miRNAs. Its unique mode of action also includes the inhibition of cancer cell growth through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing. -
Bacterial Inhibitor
Chlorprothixene hydrochloride functions as an antagonist of dopamine and histamine receptors, exhibiting Kis of 18 nM for hD1, 2.96 nM for hD2, 4.56 nM for hD3, 9 nM for hD5, and 3.75 nM for hH1 receptors. This compound demonstrates significant antipsychotic activity, making it a valuable tool for research into neuropharmacology and the mechanisms underlying psychotic disorders. Its receptor modulation also indicates potential applications in the study of bacterial inhibition mechanisms, providing insights into the interplay between neurotransmitter systems and microbial pathogenesis. -
Bacterial Inhibitor
N-Butanoyl-L-homoserine lactone (C4-HSL) is a bacterial inhibitor that functions as a signaling molecule in quorum sensing. This compound demonstrates significant antibacterial activity and effectively disrupts biofilm formation, particularly in Pseudomonas aeruginosa. Research applications include studying bacterial communication and developing strategies to combat antibiotic-resistant infections through targeted inhibition of quorum sensing pathways. -
Bacterial Inhibitor
2-Ethyl-6-methylphenol is an alkylphenol with significant antibacterial properties. This compound has demonstrated efficacy in inhibiting bacterial growth and exhibits potential insecticidal activity, making it a valuable tool in microbiological research and pest control studies. Its role as a bacterial inhibitor can facilitate investigations into microbial resistance and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Upleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Bacterial Inhibitor
Gepotidacin (S enantiomer) is a potent bacterial inhibitor that targets bacterial DNA replication and transcription processes. This compound exhibits effective antimicrobial activity against a range of gram-positive and gram-negative bacteria, making it valuable for research in infectious disease models. Its mechanism of action involves inhibition of bacterial topoisomerase, contributing to its bactericidal effects. Gepotidacin (S enantiomer) is primarily applied in studies focused on antibiotic resistance and the development of new therapeutic strategies. -
Bacterial Inhibitor
Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics. -
Bacterial Inhibitor
Ganoderol A is a terpenoid derived from Ganoderma lucidum that acts as a bacterial inhibitor. It demonstrates antimicrobial properties and plays a role in inhibiting the cholesterol synthesis pathway. Additionally, Ganoderol A exhibits significant anti-inflammatory effects and provides protection against ultraviolet A (UVA) damage, making it valuable for research in microbial resistance and skin protection strategies. -
Bacterial Inhibitor
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol with antibacterial properties. It functions by inhibiting bacterial growth, making it valuable for research in antimicrobial applications. Its isolation from Ailanthus altissima Swingle highlights its natural origins and potential utility in studies exploring microbial resistance and antibiotic development. -
Bacterial Inhibitor
Primin is a natural product that acts as a bacterial inhibitor, primarily targeting microbial growth. Isolated from the trichomes of Primula obconica, it exhibits significant antimicrobial and antitumor activities. This compound is valuable in research focused on developing antibacterial agents and cancer therapeutics. Its unique properties make it a useful tool for investigating bactericidal mechanisms and potential therapeutic applications. -
Bacterial Inhibitor
Cowaxanthone B is a xanthone compound derived from the fruits of Garcinia cowa, primarily targeting bacterial pathways. This agent exhibits moderate antibacterial activity and may be utilized in research contexts aimed at understanding bacterial inhibition mechanisms. Its potential applications include the study of antimicrobial resistance and the development of new antibacterial agents. -
Bacterial Inhibitor
Parasin I is a 19-amino acid peptide derived from histone H2A, exhibiting significant antimicrobial properties primarily against bacterial pathogens. This peptide serves as a bacterial inhibitor, making it a valuable tool for research focused on microbial resistance and the development of new antimicrobial agents. Its unique mechanism of action may provide insights for therapeutic applications in infectious disease management. -
Bacterial Inhibitor
Cinnamylideneacetic acid is a bacterial inhibitor that engages in a photoinduced [2+2] cycloaddition reaction. This compound exhibits significant antibacterial activity, making it a valuable tool for research on bacterial resistance mechanisms and the development of new antimicrobial agents. Its photoresponsive properties allow for the exploration of light-activated therapies in microbial systems. -
Bacterial Inhibitor
Triclosan-methyl is a transformation product of triclosan, functioning primarily as a bacterial inhibitor. It exhibits significant antimicrobial activity, making it relevant for applications in assessing bacterial resistance and efficacy of antimicrobial compounds. This compound is commonly utilized in research related to personal care products and their environmental impact, particularly in evaluating the persistence and degradation of antibacterial agents. -
Bacterial Inhibitor
(+)-Viroallosecurinine is a potent antibacterial alkaloid that acts as a bacterial inhibitor. It demonstrates significant antimicrobial activity, with a minimum inhibitory concentration (MIC) of 0.48 μg/mL against Pseudomonas aeruginosa and Staphylococcus aureus. This compound is suitable for research applications focused on understanding bacterial resistance and developing novel antibacterial agents. -
Bacterial Inhibitor
Ribocil-C (R enantiomer) is a selective inhibitor targeting bacterial riboflavin riboswitches. This compound disrupts riboflavin biosynthesis by binding to specific RNA structures, effectively inhibiting bacterial growth. It is useful in research applications focusing on bacterial gene regulation and the development of novel antimicrobial strategies. -
Bacterial Inhibitor
Chloroneb is a bacterial inhibitor with fungicidal properties that effectively protects plants. It is utilized in analytical applications for the detection of organochlorine pesticide residues, demonstrating excellent selectivity, stability, and reproducibility. Chloroneb has been successfully applied in the analysis of various samples, including licorice, cucumber, river water, and soil, providing reliable results for environmental monitoring and agricultural research. -
Bacterial Inhibitor
Amifloxacin is a synthetic antibacterial agent belonging to the quinolone class, primarily targeting bacterial DNA gyrase and topoisomerase IV. This compound exhibits potent bactericidal activity against a broad spectrum of gram-negative and gram-positive bacteria. It is commonly utilized in research applications for studying bacterial infections and evaluating the efficacy of antibiotic treatments. -
Bacterial Inhibitor
Lavendamycin is a quinolinedione with antimicrobial properties, primarily acting as a bacterial inhibitor. It demonstrates significant antibacterial and antitumor activity, making it a valuable compound for research in microbiology and cancer biology. Its unique mechanism and efficacy position Lavendamycin as a potential tool for exploring therapeutic approaches against bacterial infections and tumors. -
Bacterial Inhibitor
Dodine is a bacterial inhibitor with fungicidal properties, primarily targeting various plant pathogens. It is effective in controlling diseases such as black spot in apples, pears, and pecans, as well as brown rot in peaches, along with a range of foliar diseases affecting strawberries, cherries, jacaranda, and black walnuts. In addition to its agricultural applications, Dodine serves as an industrial biocide and preservative, making it valuable in diverse research settings focused on plant disease management and microbial control. -
Bacterial Inhibitor
Meso-2,6-Diaminopimelic acid serves as a critical biosynthetic precursor in the synthesis of the essential amino acid L-lysine. It plays a vital role in the formation of peptidoglycan, a key structural component of the cell walls in various bacterial species. This compound is primarily utilized in research related to bacterial inhibition and the study of cell wall biosynthesis, making it essential for antimicrobial investigations and the development of antibacterial agents. -
Bacterial Inhibitor
D-Homoserine lactone is a bacterial inhibitor that functions as a signaling molecule regulating quorum sensing through its interaction with acyl-homoserine lactone (AHL) synthase RhlI. By inhibiting RhlI activity, D-Homoserine lactone disrupts bacterial communication, making it a valuable tool in studies of bacterial behavior and pathogenicity. Additionally, as an enantiomer of L-homoserine lactone, it serves as an inhibitor of serine hydroxymethyltransferase, expanding its potential applications in biochemical research and synthetic biology. -
Bacterial Inhibitor
Afabicin disodium is a specialized bacterial inhibitor that functions as a proagent for Debio1452. It specifically targets Staphylococcus species while exhibiting minimal activity against other Gram-positive and Gram-negative bacteria. The active form, Debio1452, is an inhibitor of FabI, an enzyme essential for fatty acid biosynthesis in staphylococci, making it a valuable tool for research in combating staphylococcal infections. -
Bacterial Inhibitor
Epinecidin-1 is a potent antimicrobial peptide derived from the orange-spotted grouper (Epinephelus coioides), targeting various bacterial strains. It exhibits substantial antibacterial, antifungal, antiviral, and antiprotozoal activity, making it a valuable tool in studies examining microbial inhibition. Additionally, its immunomodulatory and wound healing properties further support research applications in infection control and regenerative medicine. -
Bacterial Inhibitor
Tuberculosis Inhibitor 3 (Compound 2i) is a potent antibacterial agent targeting Mycobacterium tuberculosis, demonstrating a minimum inhibitory concentration (MIC) of less than 0.016 μg/mL against both sensitive and resistant strains. This compound exhibits favorable pharmacokinetic properties, including adequate oral bioavailability, making it a promising candidate for further research and development in tuberculosis treatment strategies. -
Bacterial Translation Inhibitor
NOSO-502 is a bacterial translation inhibitor that targets ribosomal activity in Enterobacteriaceae. It demonstrates potent antibacterial properties while maintaining a favorable safety profile. This compound is suitable for research applications focused on bacterial protein synthesis and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Antitubercular agent-10 is a bacterial inhibitor that demonstrates potent antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 30 nM. This compound is primarily utilized in research focused on combating tuberculosis, enabling investigations into its mechanisms of action and potential therapeutic strategies. Its effectiveness makes it a valuable tool for studying mycobacterial infections and the development of novel antitubercular therapies. -
Bacterial Inhibitor
CGI-17341 is a 5-nitroimidazole antibacterial agent targeting bacterial pathogens, specifically Mycobacterium tuberculosis. This compound demonstrates significant inhibitory activity against both sensitive and multidrug-resistant strains of M. tuberculosis in vitro. In vivo studies indicate that CGI-17341 can prolong the survival time of infected mice in a dose-dependent manner, making it a valuable tool for research on tuberculosis and related bacterial infections.
