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Anti-Bacterial Agent
Dactylocycline E is an anti-bacterial agent that exhibits activity against Gram-positive bacteria. This compound is particularly valuable in the study of bacterial infections and the development of novel antimicrobial therapies. Its mechanism of action involves inhibition of bacterial protein synthesis, making it an important tool in microbiological research. -
Anti-Bacterial Agent
Fenbenicillin potassium is a semi-synthetic penicillin that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against a range of Gram-positive and certain Gram-negative bacteria. This reagent is primarily utilized in microbiological research to study bacterial infections and antibiotic resistance mechanisms. -
Anti-Bacterial Agent
Coriolin B is an anti-bacterial agent that exhibits significant activity against Gram-positive bacteria, as well as limited efficacy against Gram-negative bacteria and yeast. At a concentration of 5 μg/mL, Coriolin B demonstrates an inhibitory effect on the growth of Yoshida sarcoma by 61.6%. Notably, it shows no inhibitory effect on Ehrlich ascites carcinoma in animal models, highlighting its selective action. This compound is useful for research applications focused on antimicrobial activity and cancer biology. -
Antibacterial Peptide
Albonoursin is an antibacterial peptide derived from microbial secondary metabolites, primarily targeting bacterial cell membranes. This compound exhibits significant antibacterial activity against a range of pathogenic organisms and shows potential for antitumor activity as well. Albonoursin is valuable in research focused on antibiotic development and cancer therapeutics. -
Anti-Bacterial Agent
Curromycin A is an antibacterial agent primarily targeting Gram-positive bacteria, including Bacillus subtilis. It exhibits notable antibacterial activity and has demonstrated the ability to inhibit the replication of human immunodeficiency virus (HIV). Additionally, Curromycin A has shown efficacy against mouse melanoma B16 and leukemia P388 cell lines, making it a useful reagent for various biological research applications. -
Anti-Bacterial Agent
Cepacin B is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound can be utilized in various research applications focused on bacterial inhibition and antibiotic development. Its broad-spectrum efficacy makes it a valuable tool in microbiological studies. -
Antibacterial Agent
LY 255262 is an antibacterial agent that demonstrates potent inhibitory activity against a range of Gram-positive and Gram-negative bacteria. In vitro studies reveal minimum inhibitory concentration (MIC) values of 64 μg/mL for Staphylococcus aureus, 0.25 μg/mL for Streptococcus pneumoniae, and 0.5 μg/mL for Haemophilus influenzae, among others. Notably, LY 255262 exhibits a reduced effect on Pseudomonas species with an MIC greater than 128 μg/mL. This compound is suitable for applications in antibacterial research. -
Antibacterial Agent
Antibacterial Agent 174 targets bacterial infections through its potent anti-infective properties. This compound exhibits significant efficacy in vivo, demonstrating favorable pharmacokinetic profiles. Antibacterial Agent 174 is particularly effective in biofilm removal, while exhibiting low hemolytic activity and acceptable toxicity towards mammalian cells, making it a valuable tool for research on bacterial infections and treatment strategies. -
Anti-Bacterial Agent
Oleficin is an anti-bacterial agent that demonstrates resistance to Gram-positive bacteria. This compound has shown effectiveness in preclinical models, particularly in addressing subcutaneous transplantation of Yoshida sarcoma. Its biological activity makes it a valuable tool for research in infectious diseases and tumor biology. -
Anti-Bacterial Agent
Paulomenol A is an antibacterial agent that exhibits potent activity against Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae. This compound is of significant interest for research applications aimed at combating bacterial infections and exploring new therapeutic strategies in antimicrobial drug development. Its effectiveness in inhibiting the growth of these pathogens makes it a valuable tool for investigating antibacterial mechanisms and resistance. -
Bacterial Metabolite
Ilicicolin F is a fungal metabolite that primarily targets bacterial oxidases, specifically inhibiting T. vivax alternative oxidase and E. coli ubiquinol oxidase cytochrome bo, with IC50 values of 0.43 and 0.37 μM, respectively. It exhibits antifungal activity against Aspergillus fumigatus and Candida albicans, demonstrating minimum inhibitory concentrations ranging from 1.66 to 13.33 μg/mL. Additionally, Ilicicolin F displays significant cytotoxicity in HeLa cells, with an EC50 value of 0.003 μg/mL, making it a potent candidate for research in microbial and cancer studies. -
Antibacterial Agent
Arizonin C3 is a microbial metabolite that exhibits antibacterial activity primarily against Gram-positive bacteria. Its mechanism of action involves disrupting cell wall synthesis, making it a valuable tool for studies focused on bacterial resistance and the development of novel antimicrobial agents. Arizonin C3 is suitable for research applications in microbiology and antibiotic development. -
Antibacterial Agent
Hypercalin B is an antibacterial agent derived from the hexane and chloroform extracts of Hypericum acmosepalum. It demonstrates significant inhibitory activity against multidrug-resistant strains of Staphylococcus aureus, with a minimum inhibitory concentration (MIC) range of 0.5-128 mg/L. This compound is relevant for research applications focused on combating resistant bacterial infections and studying natural product-derived antibacterial mechanisms. -
Anti-Bacterial Agent
Cinnatriacetin A is an anti-bacterial agent derived from the fungal strain Fistulina hepatica. It exhibits selective activity against Gram-positive bacteria, making it a valuable reagent for studies focused on bacterial inhibition and resistance mechanisms. Its unique properties make it suitable for research applications in microbiology and antibiotic development. -
Anti-Bacterial Agent
Olivomycin C is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits potent activity against various strains, while demonstrating limited efficacy against Gram-negative bacteria. This compound is valuable for research applications focused on developing new antibacterial strategies and studying mechanisms of bacterial resistance. -
Bacterial Inhibitor
Fenvalerate-d6 is a deuterium-labeled derivative of Fenvalerate, primarily targeting bacterial inhibition. This compound exhibits potent antibacterial activity, making it valuable for research applications focused on elucidating bacterial resistance mechanisms and evaluating the efficacy of antibacterial agents. Its isotopic labeling enables tracking and quantification in metabolic studies and pharmacokinetic investigations. -
Anti-Bacterial Agent
Parimycin is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria, while showing no effect on fungal species. This compound has demonstrated the ability to inhibit various tumor cell lines, including GXF 251L, H640, LXFA 629L, MCF-7, and MEXF 514L, with IC70 values ranging from 0.9 to 6.7 μg/mL. Parimycin serves as a valuable research tool for studying antibacterial mechanisms and evaluating potential therapeutic strategies against certain tumors. -
Antibacterial Agent
Antibacterial Agent 313 is a broad-spectrum antibacterial compound that targets bacterial cell growth and proliferation. It demonstrates significant efficacy against a range of bacterial strains, making it a valuable tool in the study of bacterial infections. This reagent is suitable for various research applications focused on understanding antibacterial mechanisms and developing new therapeutic strategies. -
Anti-Bacterial Agent
Fumigatin is an anti-bacterial agent that exhibits activity against Gram-positive bacteria, with weaker efficacy against Gram-negative bacteria, including Vibrio cholerae. This compound is valuable in research focusing on bacterial infections and the development of novel antibacterial therapies. Its broad-spectrum properties make it a potential candidate for studies aiming to understand bacterial resistance and the mechanism of action of antibacterial agents. -
Anti-Bacterial Agent
Manumycin G is an anti-bacterial agent that primarily targets Gram-positive bacteria, demonstrating notable efficacy against Escherichia coli. While its effectiveness against Gram-negative bacteria is limited, it shows weak cytotoxic activity in human cancer cell lines, with an IC50 of 15.6 μg/mL against HCT-116. This compound is valuable in research focused on bacterial infections and cancer biology, particularly in studies involving RAS signaling pathways. -
Bacterial
Luteoreticulin is a nitro-containing bacterial metabolite targeting various biological systems, originally isolated from Sphingobacterium luteoreticuli. It exhibits significant mosquitocidal activity against Aedes aegypti, demonstrating efficacy at a concentration of 6.25 mg/L, as well as nematocidal activity against Caenorhabditis elegans. This compound is valuable for research in pest control and nematode biology. -
Anti-Bacterial Agent
Pillaromycin A is an anti-bacterial agent that exhibits activity against mycobacteria and Gram-positive bacteria, with comparatively weaker effects on Gram-negative bacteria. Additionally, this compound demonstrates antitumor properties, making it a potential candidate for research in antimicrobial and cancer therapeutics. Its diverse biological activities highlight its utility in microbiological and oncological studies. -
Anti-Bacterial Agent
Juglomycin B is an antibacterial agent with demonstrated broad-spectrum efficacy against various bacterial and mycobacterial strains. In preclinical studies, it has shown the potential to inhibit Ehrlich ascites carcinoma in murine models and extend survival at a dosage of 1 mg/kg. This compound is valuable for research in antibacterial drug development and cancer therapeutics. -
Anti-Bacterial Agent
Nocardicyclin B is an anti-bacterial agent that exhibits resistance against Gram-positive bacteria, mycobacterium, and Nocardia species. This compound's mechanism of action involves disruption of bacterial cell wall synthesis, leading to cell lysis and death. Nocardicyclin B is valuable for research applications focused on studying bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Anti-Bacterial Agent
Carpetimycin D is a potent anti-bacterial agent that exhibits strong activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. This compound effectively inhibits β-lactamase activity, making it a valuable tool for research applications aimed at understanding and combating antibiotic resistance. Its broad-spectrum efficacy makes it suitable for studying bacterial infections and developing new therapeutic strategies. -
Bacterial Inhibitor
(E/Z)-Aureusidin is a flavonoid compound that functions as a bacterial inhibitor through its antioxidant properties. It effectively inhibits the production of reactive oxygen species, thereby reducing cellular damage and inflammation by lowering the expression of inflammatory factors. Additionally, (E/Z)-Aureusidin exhibits broad-spectrum antimicrobial activity, highlighting its potential applications in combating bacterial infections and studying inflammatory responses. -
Antibacterial Agent
Tetrabutylammonium (nitrite) acts as an antibacterial agent through its ability to disrupt bacterial cellular processes. This compound demonstrates inhibitory activity against a variety of Gram-negative and Gram-positive bacteria, making it a valuable tool for research into antibacterial mechanisms and the development of new antimicrobial therapies. Its unique properties facilitate the study of bacterial resistance and sensitivity profiles in microbiological research applications. -
Anti-Bacterial Agent
Oganomycin GA is an anti-bacterial agent derived from the fermentation of Streptomyces strain oganonensis Y-G 19Z. It exhibits potent inhibitory activity against both Gram-positive and Gram-negative bacteria, attributed to its interactions with D-amino acid oxidase and its stable chemical structure. This compound is a valuable tool for research into bacterial resistance mechanisms and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Saccharocin is an antibiotic with demonstrated efficacy against both Gram-positive and Gram-negative bacteria, including strains resistant to aminoglycoside antibiotics. Its mechanism of action involves disrupting bacterial cell wall synthesis, rendering it a valuable tool in antibacterial research. This compound is applicable in studies aimed at understanding antibiotic resistance and developing new therapeutic strategies against bacterial infections. -
Antibacterial Agent
Arizonin A2 is a microbial metabolite that exhibits strong antibacterial activity, specifically targeting Gram-positive bacteria. This compound can be utilized in research focused on antibacterial agents, providing insights into microbial interactions and potential therapeutic applications against resistant strains. Its unique mechanism of action makes it a valuable candidate for studies in microbiology and drug development. -
Antibacterial Agent
BAY-Y 3118 hydrochloride is a quinolone antibacterial agent targeting bacterial infections. It demonstrates a broad antibacterial spectrum in vitro, exhibiting strong activity against gram-positive cocci and anaerobes, with moderate efficacy against Enterobacteriaceae and Pseudomonas aeruginosa. This reagent is useful for research applications in infectious diseases, providing a valuable tool for studying antibacterial mechanisms and resistance. -
Antibacterial Agent
(E)-Pinocembrin chalcone is an antibacterial compound derived from Helichrysum trilineatum. It exhibits significant antibacterial activity, making it a valuable reagent for research applications focused on bacterial infections and antimicrobial studies. This compound serves as a potential lead for the development of novel antibacterial agents. -
Anti-Bacterial Agent
Fosfadecin is an anti-bacterial agent that demonstrates moderate antibacterial activity. It is utilized in research to study bacterial infections and evaluate potential therapeutic strategies against bacterial pathogens. Its mechanism of action may provide insights into the development of new antibacterial compounds. -
Antibacterial Agent
Aspersitin is a bioactive metabolite derived from Aspergillus parasiticus, exhibiting potent antibacterial properties. This compound has demonstrated effectiveness against various bacterial strains, making it a valuable research tool in the study of antibacterial mechanisms and the development of new antimicrobial agents. Its utility extends to exploring the biochemical pathways involved in bacterial resistance and susceptibility. -
Antibacterial Agent
Fusaricidin B is an antibacterial agent derived from the lipopeptide biosurfactant of the marine bacterium Paenibacillus polymyxa. This compound exhibits significant inhibitory effects on the formation of biofilms across various bacterial species, including both Gram-positive and Gram-negative bacteria. Additionally, Fusaricidin B demonstrates the ability to disrupt complex and mature biofilms, making it a valuable tool for research into bacterial infections and biofilm-related challenges. -
Anti-Bacterial Agent
Cyathin A3 is an anti-bacterial agent with demonstrated activity against Gram-positive bacteria, Gram-negative bacteria, actinomycetes, and dermatophytes. In addition to its anti-bacterial properties, Cyathin A3 exhibits protective effects in ischemic conditions, showing potential for improving cerebral ischemia in relevant rat models. This compound is valuable for research in microbiology and neurological studies. -
Anti-Bacterial Agent
Chrysospermin D functions as an anti-bacterial agent, exhibiting potent antibacterial activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as Klebsiella pneumoniae. Additionally, it demonstrates efficacy against specific yeasts such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is useful for research applications focused on bacterial and yeast infections, as well as studies investigating antibacterial mechanisms. -
Anti-Bacterial Agent
Carpetimycin B is a potent anti-bacterial agent known for its robust activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. It effectively inhibits β-lactamase activity, making it a valuable tool for research on antibiotic resistance and bacterial infections. This compound is particularly relevant in studies aimed at understanding bacterial mechanisms and developing novel antibacterial therapies. -
Bacterial Metabolite
Reveromycin B is a spiroketal bacterial metabolite that targets epidermal growth factor (EGF) signaling. It effectively inhibits EGF-induced mitogenic activity in Balb/MK cells with an IC50 of 6 μg/mL. Additionally, Reveromycin B displays pH-dependent antifungal properties against Candida albicans, with minimum inhibitory concentrations (MICs) of 15.6 μg/mL at pH 3.0 and greater than 500 μg/mL at pH 7.4, while showing no inhibitory effect on the proliferation of KB and K562 cells. This compound is useful for studying EGF signaling pathways and exploring antifungal mechanisms. -
Anti-Bacterial Agent
11-Deoxydoxorubicin is an anthracycline compound that demonstrates significant antibacterial activity against Gram-positive bacteria as well as notable efficacy against Gram-negative bacteria and tumors. It is utilized in research focused on microbial resistance mechanisms and potential therapeutic interventions for bacterial infections, making it a valuable tool for studying both antibacterial and anticancer properties. -
Anti-Bacterial Agent
Saframycin G is an anti-bacterial agent predominantly effective against Gram-positive bacteria. It exhibits notable cytotoxic activity by inhibiting mouse lymphocyte L-1210 cells, with an ID50 value of 0.03 µM. This compound has potential applications in antibacterial research and the study of lymphocyte proliferation. -
Anti-Bacterial Agent
Heneicomycin is an anti-bacterial agent that exhibits activity against Gram-positive and Gram-negative bacteria, as well as mycoplasma. Its broad-spectrum antimicrobial properties make it valuable for research applications in microbiology and veterinary studies. Additionally, Heneicomycin has been reported to promote animal growth, highlighting its potential in agricultural and animal health research. -
Antibacterial Synergist
Isoreserpiline is an orally active indole alkaloid that functions as an antibacterial synergist by inhibiting bacterial efflux pumps. This compound exhibits both antibacterial and antipsychotic properties and is particularly effective when used in combination with antibiotics. Isoreserpiline has also shown to mitigate amphetamine-induced hyperactivity in animal models, highlighting its potential utility in neuropharmacological research. -
Anti-Bacterial Agent
Amicenomycin B is an anti-bacterial agent with specific activity against Gram-positive bacteria. This compound exhibits potent antimicrobial effects and is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies. Its unique mode of action offers insights into bacterial cell wall synthesis and potential targets for novel antibiotic design. -
Anti-Bacterial Agent
Citreamicin γ is an antibacterial agent effective against Gram-positive aerobic and anaerobic bacteria. This compound exhibits significant antimicrobial activity, making it a valuable tool in studying bacterial infections and resistance mechanisms. Its potential applications extend to research involving antibiotic development and evaluating the efficacy of antibacterial therapies. -
Antibacterial Agent
(1,5-Cyclooctadiene)dimethylplatinum(II) is an antibacterial agent that targets specific bacterial strains. It demonstrates selective activity against certain Gram-positive bacteria, including methicillin-resistant *Staphylococcus aureus* (MRSA) and glycopeptide-intermediate *Staphylococcus aureus* (GISA). Notably, this compound exhibits no hemolytic activity, highlighting its potential for therapeutic applications in treating resistant bacterial infections. -
Anti-Bacterial Agent
Kibdelin A is an anti-bacterial agent that exhibits effective resistance against Gram-positive bacteria. It demonstrates comparable activity to Vancomycin against Staphylococcus aureus, including methicillin-resistant strains. This compound is relevant for research studies focusing on antibiotic resistance and the development of new therapeutic strategies. -
Antibacterial Agent
WCK-1152 is a fluoroquinolone antibacterial agent that targets DNA gyrase and topoisomerase IV. It exhibits significant activity against resistant pathogens, including those with mutations in these enzymes and expressing efflux pumps. This compound is suitable for research focused on infections, particularly respiratory infections caused by resistant strains of pneumococci and staphylococci. -
Anti-bacterial Agent
Tylosin lactate is an anti-bacterial agent effective against spore-forming bacteria. It promotes the growth of Enterococcus and lactobacilli, making it useful in studies related to gastrointestinal health. Tylosin lactate is also employed in research focused on alleviating tylosin-responsive diarrhea in canine models. -
Bacterial Metabolite
Reveromycin D is a bacterial metabolite derived from Streptomyces, known for its ability to inhibit EGF-induced mitogenic activity in Balb/MK cells. This compound exhibits pH-dependent antifungal activity against Candida albicans, with minimum inhibitory concentrations (MICs) of 2 μg/mL at pH 3 and >500 μg/mL at pH 7.4. Additionally, Reveromycin D demonstrates significant antiproliferative effects on KB and K562 cancer cell lines, with IC50 values of 1.6 and 1.3 μg/mL, respectively, making it valuable for research in cell signaling and cancer therapeutics.

