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Antibacterial Agent
(E)-2-(4-Cinnamoylphenoxy)acetic acid functions as an antibacterial agent. It exhibits potent antimicrobial activity, demonstrating a minimum inhibitory concentration of 125 μg/mL against various pathogens, including Mycobacterium smegmatis, Staphylococcus aureus, and Candida albicans. This compound is valuable for research applications focused on antimicrobial resistance and the development of new therapeutic agents. -
Anti-Bacterial Agent
Fomecin A is an anti-bacterial agent that exhibits significant activity against Gram-positive bacteria, with weaker effects observed against Gram-negative bacteria and fungi. Its mechanism of action involves disruption of bacterial cell wall synthesis, making it a valuable tool for research focused on combating bacterial infections. Fomecin A can be utilized in studies exploring the efficacy of new antimicrobial compounds and their potential applications in clinical settings. -
Anti-Bacterial Agent
2"-N-Formimidoylsporaricin A is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria, including strains resistant to aminoglycosides. This compound demonstrates potent antibacterial properties, making it a valuable tool for microbiological research and the development of new therapeutic strategies against resistant bacterial infections. Its broad-spectrum efficacy positions it as a significant candidate for studies focused on antimicrobial resistance and therapeutic intervention. -
Anti-Bacterial Agent
Azicemicin A is an antibacterial agent that exhibits weak antibacterial activity. It has been shown to possess no acute toxicity in mouse models, making it a potential candidate for further research in antibiotic development and safety assessments. Its unique properties may facilitate investigations into the mechanisms of antibiotic action and resistance. -
Anti-Bacterial Agent
Megovalicin B is an anti-bacterial agent that exhibits potent activity against Bacillus subtilis and Escherichia coli. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial therapies. Its efficacy in inhibiting pathogenic microbial growth makes it an important tool in microbiology and pharmaceutical development. -
Anti-Bacterial Agent
Ostreogrycin B3 is an anti-bacterial agent targeting Gram-positive bacteria. This compound exhibits significant inhibitory effects against various strains, making it suitable for studies in microbial resistance and antibacterial efficacy. It is a valuable reagent for research applications focused on developing new therapeutics for bacterial infections. -
Antibacterial Agent
VPC162134 is an antibacterial agent that targets and inhibits pyruvate ferredoxin oxidoreductase (PFOR), showing effectiveness against H. pylori, C. jejuni, MRSA, and S. epidermidis with minimum inhibitory concentrations (MIC) of 2.9, 17.5, 93.3, and 93.3 μM, respectively. Its notable antibacterial properties make it useful for research in combating antibiotic-resistant bacteria and understanding microbial resistance mechanisms. -
Bacterial
2,3-Diphenylquinoxaline-6-sulphonamide acts as an antibacterial agent targeting bacterial pathways. This compound demonstrates significant antibacterial activity, making it suitable for research applications focused on bacterial infections. Additionally, it exhibits analgesic and anti-inflammatory properties, providing insights into its potential therapeutic roles beyond antimicrobial effects. -
Anti-Bacterial Agent
Cerexin D4 is an anti-bacterial agent targeting Gram-positive bacteria. It exhibits significant activity against various strains, making it a valuable tool in the study of bacterial infections and the development of new therapeutic strategies. Researchers can utilize Cerexin D4 in investigations related to antibiotic resistance and the efficacy of antibacterial compounds. -
Anti-Bacterial Agent
Chrysospermin B is an anti-bacterial agent that demonstrates significant activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as the pathogen Klebsiella pneumoniae. Additionally, it exhibits efficacy against specific yeasts such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is valuable for investigations into bacterial and fungal infections and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Glucosylquestiomycin is an anti-bacterial agent that targets both Gram-positive and Gram-negative bacteria, as well as yeast. Its broad-spectrum activity makes it a valuable tool in microbiological research and the development of new antimicrobial therapies. Researchers can utilize Glucosylquestiomycin to investigate bacterial resistance mechanisms and explore potential applications in infection control. -
Bacterial
Linearmycin A is a polyene antibiotic targeting bacterial pathogens, derived from Streptomyces. It demonstrates significant antimicrobial activity against Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentrations (MICs) of 3.1 and 1.6 μg/disc, respectively. Additionally, Linearmycin A exhibits antifungal properties, inhibiting Saccharomyces cerevisiae and Candida albicans with MICs of 0.1 and 1.6 μg/disc, respectively, and also shows effectiveness against the plant pathogenic fungus Aspergillus niger (MIC=0.2 μg/disc). This compound is valuable in research applications focused on bacterial and fungal infections, as well as the mechanisms of antibiotic action. -
Anti-Bacterial Agent
Carpetimycin A is a potent anti-bacterial agent that demonstrates robust activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. This compound effectively inhibits β-lactamase activity, making it a valuable tool for research focused on antibiotic resistance mechanisms and potential therapeutic development. Its broad-spectrum efficacy positions Carpetimycin A as an important reagent for studies in microbiology and infectious disease. -
Antibacterial Agent
HT-61 is a quinolone antibacterial agent that demonstrates potent bactericidal activity against gram-positive bacteria, including both methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). This compound shows potential in enhancing the efficacy of Tobramycin against Pseudomonas aeruginosa, making it a valuable tool for research on antibiotic resistance and mechanisms of bacterial infection. Its applications span microbiological studies and the development of novel antibacterial therapies. -
Antibacterial Agent
Apalcillin sodium is an antibacterial agent effective against carbenicillin- and ampicillin-resistant strains of gram-negative bacilli. It functions by inhibiting bacterial cell wall synthesis, demonstrating significant activity in combating various bacterial infections. This reagent is particularly useful in research applications focused on antibiotic resistance and the development of new antibacterial therapies. -
Antibacterial Agent
HMRZ-62 is an antibacterial agent that targets Gram-positive bacteria. It exhibits potent antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus faecalis (VRE). HMRZ-62 is particularly valuable for research focused on overcoming antibiotic resistance and developing new therapeutic strategies against resistant bacterial infections. -
Anti-Bacterial Agent
Carpetimycin C is an anti-bacterial agent that exhibits potent activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. This compound effectively inhibits β-lactamase activity, making it a valuable tool in research aimed at understanding and combating antibiotic resistance in bacterial infections. Its significant biological effects provide insights into potential therapeutic applications in the field of microbiology. -
Anti-Bacterial Agent
Megovalicin G is an anti-bacterial agent that targets bacterial cells, exhibiting potent activity against Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. This compound is valuable for research applications focused on understanding bacterial resistance mechanisms and developing new antimicrobial therapies. Its broad-spectrum efficacy makes it suitable for studies in microbiology and pharmaceutical development. -
Anti-Bacterial Agent
Nocathiacin I is a potent anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits strong efficacy against methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and multidrug-resistant Enterococcus faecalis (MREF). Nocathiacin I is valuable for research applications focused on combating antibiotic-resistant infections and understanding bacterial resistance mechanisms. -
Antibacterial Agent
LMW peptide is an antimicrobial peptide that targets a broad spectrum of bacterial strains. It exhibits significant antibacterial activity against both Gram-positive bacteria, such as Bacillus subtilis and Listeria monocytogenes, as well as Gram-negative bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Vibrio cholerae. This makes LMW peptide a valuable reagent for research applications aimed at investigating antimicrobial mechanisms and developing new antibacterial therapies. -
Anti-Bacterial Agent
Polymyxin P1 is an anti-bacterial agent derived from Bacillus polymyxa T-39, known for its ability to inhibit Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it a valuable tool for studying bacterial infections and developing antimicrobial therapies. Its unique mechanism of action targets the bacterial cell membrane, disrupting integrity and function. Research applications include evaluating bacterial resistance and testing the efficacy of antibacterial compounds in various experimental models. -
Anti-Bacterial Agent
Cremeomycin is an anti-bacterial agent with potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.2-0.39 μg/mL. In addition to its antibacterial properties, Cremeomycin demonstrates significant cytotoxicity against various mouse tumor cell lines, such as P388, L1210, IMC, S180, B16, and SS3 in vitro. This compound is valuable in research focused on antibiotic resistance and anticancer therapies. -
Antibacterial Agent
PNU-140457 is an antibacterial agent that targets the 30S ribosomal subunit, effectively inhibiting bacterial protein synthesis. It demonstrates significant antibacterial activity, making it a valuable tool in the study of bacterial infections. This compound is suitable for use in research applications aimed at understanding and combating bacterial growth and resistance mechanisms. -
Anti-Bacterial Agent
Saframycin E is an anti-bacterial agent that primarily targets Gram-positive bacteria, demonstrating effective inhibitory activity against this group. Additionally, it exhibits weak activity against mycobacteria, making it relevant for research in bacterial infections and antibiotic resistance mechanisms. This compound is of interest for studies focused on the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Diperamycin is an anti-bacterial agent primarily targeting Gram-positive bacteria, such as Enterococcus seriolicida and methicillin-resistant Staphylococcus aureus (MRSA), with observed minimum inhibitory concentrations (MICs) ranging from 0.10 to 0.20 μg/mL. Additionally, Diperamycin exhibits potent cytotoxic activity against various cancer cell lines, including L1210, P388, LS-180, KB, HeLaS3, Meth A, and B16-BL6, with IC50 values between 0.009 and 0.098 μg/mL. This compound is valuable for research focusing on bacterial resistance and cancer-related investigations. -
Bacterial Inhibitor
Chevalone B is a bacterial inhibitor derived from the marine sponge-associated fungus Aspergillus similanensis. It exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as Candida albicans and multidrug-resistant environmental strains. Its potential applications in antimicrobial research highlight its significance in the development of novel therapeutic agents. -
Antibacterial Agent
SCH 25393 is a potent antibacterial agent that targets bacterial growth mechanisms. Its biological activity includes inhibiting the proliferation of various bacterial strains, making it valuable for research applications in microbiology and antibiotic resistance studies. This compound serves as a useful tool for investigating the efficacy of new antibacterial therapies and understanding bacterial pathogenesis. -
Antibacterial Agent
Leptosperin is a glycoside derivative of methyl syringate, primarily sourced from manuka honey of the Leptospermum scoparium species. This compound demonstrates notable antibacterial properties, making it a valuable tool for studying bacterial infections and developing potential therapeutic agents. Its unique activity profile may provide insights into the mechanisms of action and efficacy in various infection-related research applications. -
Bacterial
BAS00127538 is a Lipid II inhibitor known for its antibacterial activity. As the first small molecule of its kind, BAS00127538 exhibits a unique structure that differentiates it from naturally occurring Lipid II binders, like vancomycin. Its binding affinity for Lipid II and associated cytotoxicity are critical to its mechanisms of action against bacterial infections. Research applications include investigating its potential as a therapeutic agent in combatting antibiotic-resistant bacterial strains. -
Anti-Bacterial Agent
Dienomycin A is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria and mycobacteria. This compound is valuable in research applications focusing on bacterial infections and antibiotic resistance mechanisms. Its unique mechanism of action makes it a useful tool for studying bacterial physiology and developing new antimicrobial therapies. -
Anti-Bacterial Agent
Pyloricidin A2 is an antibiotic that specifically targets Helicobacter pylori, derived from Bacillus sp. HC-70. This compound exhibits potent antibacterial activity against H. pylori, making it a valuable tool for research into gastric pathogens. Notably, Pyloricidin A2 shows no activity against other bacterial strains or yeast, underscoring its specificity. -
Anti-Bacterial Agent
4"-Demethylgentamicin C1 functions as an anti-bacterial agent, exhibiting potent activity against both Gram-positive and Gram-negative bacteria. Its key biological activity underscores its potential in combating bacterial infections, making it a valuable reagent for microbiological research and applications in antibiotic susceptibility testing. -
Anti-Bacterial Agent
Rifamycin L, an anti-bacterial agent, exhibits potent activity against a variety of Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial RNA synthesis, effectively interfering with transcription processes. This compound is widely utilized in microbiological research to study bacterial resistance mechanisms and to develop new therapeutic strategies against infectious diseases. -
Anti-Bacterial Agent
Oxasetin is an antibacterial agent with selective activity against Gram-positive bacteria, exhibiting a minimum inhibitory concentration (MIC) of 16 μg/mL against Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis. It demonstrates no efficacy against Gram-negative bacteria or fungi. This compound serves as a valuable tool for research focused on combating resistant bacterial infections. -
Antibacterial Agent
(R)-Mucronulatol is a flavonoid with antibacterial properties, primarily isolated from Astragalus adsurgens. This compound exhibits significant antibacterial activity against a range of pathogens, including Escherichia coli, Bacillus cereus, Staphylococcus aureus, Erwinia carotovora, and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 15.5, 15.5, 7.8, 7.8, and 15.5 µg/mL, respectively. Its potential applications include the study of antibacterial mechanisms and the development of new antimicrobial agents. -
Anti-Bacterial Agent
5-Deoxygentamicin C1 is an anti-bacterial agent that exhibits potent activity against both Gram-positive and Gram-negative bacteria. It is commonly utilized in microbiological research to study bacterial resistance mechanisms and the efficacy of antibiotic treatments. This compound serves as a valuable tool for exploring the therapeutic potential of aminoglycosides in combating bacterial infections. -
Antibacterial Agent
Antibacterial Agent 279 is a potent antibacterial compound that specifically targets the SOS response in Pseudomonas aeruginosa. This agent exhibits significant antibacterial activity, making it suitable for research focused on bacterial resistance mechanisms and the development of novel antimicrobial therapies. Its efficacy in modulating bacterial stress responses supports studies aimed at understanding and combating multidrug-resistant infections. -
Anti-Bacterial Agent
Kigamicin D acts as an effective anti-bacterial agent, demonstrating activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with minimum inhibitory concentrations (MICs) ranging from 0.025 to 0.78 μg/mL. In addition to its antibacterial properties, Kigamicin D exhibits cytotoxicity against L-1210 LB32T and various tumor cell lines, showing an IC50 of 1 μg/mL. This compound is valuable in research focused on combating resistant bacterial strains and investigating therapeutic options for cancer treatment. -
Antibacterial Agent
2-Chloroisonicotinohydrazide is an antibacterial agent primarily targeting Mycobacterium tuberculosis. It demonstrates significant antibacterial activity, exhibiting a MIC50 of 392.0 μM against the H37Rv strain. This compound serves as a valuable tool for research applications focused on tuberculosis and the development of novel therapeutic strategies. -
Anti-Bacterial Agent
Kibdelin C2 is an effective anti-bacterial agent targeting Gram-positive bacteria, exhibiting potent activity against Staphylococcus aureus, including methicillin-resistant strains. Its mechanism of action parallels that of Vancomycin, making it a valuable reagent for research into bacterial resistance and infection treatments. This compound is suitable for studies aimed at exploring novel therapeutic options against resistant bacterial pathogens. -
Bacterial
18:1-14:0 PC is an asymmetric phospholipid that features an unsaturated acyl chain in the sn-1 position. This compound acts as a surfactant, creating a hydrophobic surface in mucus that impedes bacterial penetrance. Additionally, it serves as a dietary source of choline, making it valuable for research applications related to bacterial interactions and membrane dynamics. -
Anti-Bacterial Agent
Cycloheptamycin is an anti-bacterial agent that demonstrates significant activity against Gram-positive bacteria and mycobacteria. Its unique structure allows it to disrupt bacterial cell processes, making it a valuable tool for microbiological research and antibiotic development. This compound is particularly useful in studies focused on combating resistant strains of bacteria. -
Anti-Bacterial Agent
Chimeramycin B is an anti-bacterial agent targeting Gram-positive bacteria and mycoplasma. It exhibits potent inhibitory activity against a range of these microorganisms, making it a valuable tool in microbiological research. This compound is particularly useful in studying bacterial resistance mechanisms and evaluating potential therapeutic applications against infections caused by Gram-positive pathogens. -
Antibacterial Agent
Antibacterial Agent 322 is a potent antibacterial compound that targets and inhibits the growth of various bacterial strains. Its primary mechanism involves disrupting bacterial cell proliferation, making it suitable for research on bacterial infections and the development of new antimicrobial therapies. Utilize Antibacterial Agent 322 to explore bacterial resistance mechanisms and evaluate therapeutic efficacy in preclinical studies. -
Anti-Bacterial Agent
Lycomarasmin is an anti-bacterial agent that targets Lactobacillus casei. This compound exhibits inhibitory effects on the growth of this specific bacterial strain, providing potential applications in microbiological research and the study of bacterial interactions. Its plant-derived nature underscores its utility in exploring natural products for antimicrobial properties. -
Bacterial Ribosome Inhibitor
Capreomycin IA is a bactericidal agent that inhibits bacterial ribosomes, primarily affecting mycobacterial species. By blocking the translocation of peptidyl-transfer RNA from the A to the P site, Capreomycin IA effectively interrupts protein synthesis. This compound demonstrates significant antimicrobial activity against Mycobacterium tuberculosis and is useful for research applications related to tuberculosis and other mycobacterial infections. -
Anti-Bacterial Agent
Pacidamycin 4N is an antibiotic that targets Pseudomonas aeruginosa, exhibiting a minimal inhibitory concentration (MIC) range of 4-16 μg/mL. This compound demonstrates selective antibacterial activity specifically against this pathogen, with no discernible effect on other Gram-negative or Gram-positive bacteria, including drug-resistant strains of Pseudomonas aeruginosa. It is a valuable tool for research on bacterial infections and the development of targeted antimicrobial therapies. -
Anti-Bacterial Agent
Juglomycin A, an anti-bacterial agent, exhibits a broad spectrum of antibacterial and mycobacterial activity. Notably, it has demonstrated efficacy in inhibiting Ehrlich ascites carcinoma in murine models, leading to extended survival rates at a dosage of 1 mg/kg. This compound is of significant interest in research applications aimed at understanding microbial resistance and cancer therapeutic interventions. -
Anti-Bacterial Agent
Paulomenol B is an anti-bacterial agent effective against Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae. This compound exhibits significant inhibitory effects on bacterial growth, making it a valuable tool for research in microbiology and infectious disease. Its application may extend to the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Cephaibol B is an anti-bacterial agent primarily effective against Gram-positive bacteria. This compound exhibits notable anti-bacterial activity while lacking efficacy against Gram-negative strains. In addition to its antibacterial properties, Cephaibol B also demonstrates deworming effects and activity against ectoparasites, making it relevant for research applications in microbiology and parasitology.

