Shop By
Catalog No.
Product Name
Application
Product Information
Citations
-
Fungal Inhibitor
Dihydrochelerythrine is a natural compound derived from Corydalis yanhusuo, primarily functioning as a fungal inhibitor. This compound exhibits notable antifungal activity, making it a valuable reagent for research applications focused on mycology and the study of fungal infections. Its properties may contribute to the development of novel antifungal therapies. -
Fungal Inhibitor
Cauloside A, a saponin derived from the roots of Dipsacus asper, serves as a potent fungal inhibitor. It exhibits significant antifungal activity, making it a valuable reagent for research focused on fungal pathogenesis and therapeutic interventions. Its effectiveness in combating various fungal strains positions Cauloside A as a crucial tool in the study of antifungal mechanisms and the development of new antifungal agents. -
Bacterial Inhibitor
Bafilomycin B1 is a macrolide antibiotic that targets vacuolar H+-ATPases (V-ATPases). It exhibits neuroprotective properties against Chloroquine-induced cell death and can significantly inhibit the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL). Bafilomycin B1 is valuable for research focused on bacterial inhibition and studying lipid metabolism and cellular stress responses. -
PI-3 Virus Inhibitor
Tetrahydroepiberberine is an isoquinoline alkaloid derived from Corydalis impatiens. It exhibits significant antifungal properties and demonstrates selective inhibitory effects against the PI-3 virus. This compound is valuable for research applications focused on viral pathogenesis and the development of antiviral therapeutics. -
Tyrosinase Inhibitor
Geranic acid is a tyrosinase inhibitor with demonstrated antifungal properties, exhibiting an IC50 range of 0.14-2.3 mM against mushroom tyrosinase. This compound significantly reduces the viability of human pancreatic cancer cells and B-lymphoma cells, highlighting its potential in cancer research. Additionally, geranic acid effectively inhibits the mycelial growth of maize pathogens such as Colletotrichum graminicola and Fusarium graminearum. It serves as a valuable reagent for studies on fungal infections, pancreatic cancer, and B-lymphoma. -
Fungal Inhibitor
Xanthyletin is a coumarin compound derived from Stauranthus perforatus that acts primarily as a fungal inhibitor. It exhibits notable anti-tumor and antibacterial activities, making it valuable for various research applications in microbiology and cancer studies. Additionally, Xanthyletin effectively inhibits the symbiotic fungus cultivated by leaf-cutting ants, further highlighting its potential in ecological and agricultural research. -
Cytochrome P-450 Inhibitor
Flusilazole is a potent cytochrome P-450 inhibitor with broad-spectrum fungicidal activity. It is commonly employed in research related to fungal infections, providing insights into metabolic pathways and therapeutic interventions. Its mechanism of action offers valuable applications in evaluating and understanding the role of P-450 enzymes in various biological contexts. -
CHS Inhibitor
2,3,5-Tri-O-benzyl-D-ribose is a potent inhibitor of chitin synthase (CHS) in Botrytis cinerea, exhibiting an IC50 value of 1.8 μM. This compound demonstrates significant antifungal activity, capable of inhibiting the B. cinerea BD90 strain with a minimum inhibitory concentration (MIC) of 190 μM. It is valuable for research applications aimed at understanding fungal growth and developing novel antifungal agents. -
Chitinase Inhibitor
Cyclo(Arg-Pro) is a potent chitinase inhibitor that effectively inhibits cell separation in Saccharomyces cerevisiae without compromising its growth. Additionally, Cyclo(Arg-Pro) prevents the morphological transition of Candida albicans from its yeast form to a filamentous state. This compound is valuable for research applications involving fungal morphology and cell separation processes. -
Fungal Inhibitor
Dihydrosanguinarine is a natural compound known for its antifungal properties, primarily acting as a fungal inhibitor. Isolated from the leaves of Macleaya microcarpa, it exhibits significant biological activity against various fungal species. This compound has potential research applications in investigating antifungal mechanisms and exploring its anticancer properties. -
Antifungal/Exosome Inhibitor
Neticonazole is an imidazole derivative that functions as a potent and long-lasting antifungal agent. Its primary mechanism involves inhibiting fungal cell membrane synthesis, making it effective against a variety of fungal infections. Additionally, Neticonazole exhibits anti-infective and potential anti-cancer properties, making it valuable for research applications in both infectious disease and cancer therapy. -
Fungal Inhibitor
Corypalmine is a naturally occurring alkaloid derived from Stephania cepharantha, known for its antifungal properties. It primarily targets fungal cells, inhibiting their growth and proliferation. This compound is useful in various research applications focused on fungal infections and the development of antifungal therapies. -
Fungal Inhibitor
Multifungin (Bromochlorosalicylanilide) is a potent antifungal agent that inhibits fungal growth, making it particularly effective in treating oral candidiasis. This compound disrupts the formation and accumulation of Zearalenone and is effective in reducing fungal populations in stored-crushed corn. Multifungin is valuable for various research applications aimed at understanding fungal infections and developing antifungal therapies. -
CaFBA Inhibitor
FBA-IN-1 is a first-in-class, covalent allosteric inhibitor of fructose-1,6-bisphosphate aldolase (CaFBA) derived from Candida albicans. This compound effectively inhibits the growth of azole-resistant strains with a minimum inhibitory concentration (MIC80) of 1 µg/mL. Its unique mechanism of action positions FBA-IN-1 as a valuable tool in antifungal research, particularly for studying drug-resistant pathogens and exploring new therapeutic avenues. -
Chitin Deacetylase Inhibitor
Benzohydroxamic acid (BHA) is a potent inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal activity. With Ki values of 8.31 μM against CDA from Verticillium dahliae and 9.83 μM against CDA from Puccinia striiformis f. sp. tritici, BHA effectively restores defense responses in infected host plants by upregulating defense-related gene expression. Its application is crucial in research focused on mitigating agricultural fungal diseases, including those caused by Verticillium dahliae and Puccinia striiformis, contributing to the control of cotton wilt and wheat stripe rust. -
Antifungal Agent/HIV-1 Inhibitor
Amphotericin B methyl ester is a methyl ester derivative of the polyene antibiotic Amphotericin B, targeting cell membranes through cholesterol binding. Exhibiting potent antifungal activity, it effectively disrupts the structural integrity of fungal cells. Additionally, Amphotericin B methyl ester has demonstrated the ability to inhibit HIV-1 particle production and replication, making it valuable for research in both antifungal therapies and HIV-1 studies. -
Fungal Gwt1 Enzyme Inhibitor
APX2039 is a potent inhibitor of the fungal Gwt1 enzyme, functioning through its ability to disrupt glycosylphosphatidyl inositol (GPI) anchoring of cell wall mannoproteins. This compound demonstrates significant anticryptococcal activity against Cryptococcus neoformans and Cryptococcus gattii. APX2039 is applicable in research focused on Cryptococcal meningitis (CM) and offers valuable insights into fungal pathogenesis and treatment strategies. -
Fungal Inhibitor
Triflumizole is an imidazole fungicide that functions by inhibiting ergosterol biosynthesis, which is essential for fungal cell membrane integrity. This compound is effective against a range of fungal pathogens, particularly in the management of powdery mildew and scabs on various fruits and crops. It serves as a valuable tool in agricultural research and crop protection strategies. -
Fungal Inhibitor
Viridicatol is a quinolinone alkaloid derived from the fermentation of the endophytic fungus Penicillium sp. R22 in Nerium indicum. This compound exhibits significant antifungal activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 15.6 μg/mL. Viridicatol is suitable for research applications focused on fungal inhibition and antimicrobial activity studies. -
eEF2 Inhibitor
Sordarin sodium is an inhibitor of eEF2, targeting the diphthamide modification essential for its function. By obstructing the binding of eEF2 to the ribosome complex, Sordarin sodium effectively inhibits protein synthesis. Additionally, Sordarin sodium exhibits antifungal activity, making it valuable for research in the fields of microbiology and antifungal drug development. -
Fungal Inhibitor
Cyproconazole is a triazole fungicide that primarily targets fungal pathogens, offering effective protection for crops, fruits, and vegetables. Its biological activity includes the induction of hepatocellular adenomas and carcinomas in CD-1 mice, while demonstrating low toxicity to zebrafish embryos and impacting their locomotor activity. This compound is applicable in agricultural research and studies focused on toxicology and environmental effects of fungicides. -
Bacterial Inhibitor
Robinetin, a naturally occurring flavonoid, primarily acts as a bacterial inhibitor. This compound exhibits diverse biological activities, including antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant properties. Additionally, Robinetin has demonstrated the ability to inhibit lipid peroxidation and protein glycosylation, making it valuable for various research applications in microbiology and biochemistry. -
Fungal Inhibitor
Methyl p-coumarate is an esterified derivative of p-Coumaric acid, functioning primarily as a fungal inhibitor. It exhibits significant inhibition of melanin production in B16 mouse melanoma cells, indicating potential roles in cancer research. Additionally, Methyl p-coumarate demonstrates potent in vitro activity against various pathogens, including Alternaria alternata, making it a valuable reagent for studies in antifungal activity and therapeutic applications. -
Aldolase Inhibitor
Phosphoglycolohydroxamic acid is a potent inhibitor of aldolase and triose-phosphate isomerase, demonstrating significant potential in disrupting metabolic pathways. This compound is primarily utilized in research related to antibacterial and antifungal mechanisms, allowing for the exploration of novel therapeutic strategies against microbial infections. Its ability to inhibit key enzymes positions it as a valuable tool in biochemical studies. -
Fungal Melanization Inhibitor
Coniferin is a glucoside derivative of coniferyl alcohol that functions as a fungal melanization inhibitor. It effectively disrupts the melanin biosynthesis pathway in fungi, making it useful for studies of fungal growth and pathogenicity. Additionally, Coniferin has been shown to inhibit the release of inflammatory mediators such as Prostaglandin E2 and Thromboxane B2, highlighting its potential in research focused on cellular signaling and inflammation. -
Cytochrome bc1 Inhibitor
Inz-5 is a selective inhibitor of the mitochondrial cytochrome bc1 complex, targeting fungal pathogens. This compound effectively impairs fungal virulence and may prevent the development of resistance to antifungal agents. Its unique mechanism of action makes it a valuable tool for research in mycology and antifungal drug development. -
Bacterial Inhibitor
Tricyclazole is a pentaketone compound that acts as a bacterial inhibitor primarily by disrupting melanin biosynthesis in fungi. This unique fungicide is effective in controlling rice blast disease by altering the structure and function of fungal cell walls, thereby reducing pathogenicity and penetration. Tricyclazole’s mechanism of action also highlights its potential for studying fungal biology and the effects of melanin on fungal virulence. -
Fungal Inhibitor
Enfumafungin is a triterpene glycoside that acts as a potent fungal inhibitor by targeting (1,3)-beta-D-glucan synthase in the fungal cell wall. This compound exhibits selective antifungal activity against yeasts and filamentous fungi, excluding Cryptococcus, and is not active against Bacillus subtilis. Enfumafungin is valuable for research applications focused on fungal pathogenesis and the development of antifungal therapeutics. -
SDH Inhibitor
SDH-IN-1 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 4.53 μM. This compound demonstrates significant antifungal properties, particularly effective against S. sclerotiorum with an EC50 of 0.14 mg/L. SDH-IN-1 is a valuable tool for researchers studying fungal pathogenesis and metabolism, providing insights into SDH's role in cellular respiration and therapeutic strategies against fungal infections. -
Fungal Inhibitor
Thiophanate-Methyl is a systemic fungicide that targets fungal pathogens by inhibiting mycelial growth and spore germination. This compound exhibits broad-spectrum activity against a variety of fungi, making it useful in agricultural applications for disease management in crops. Its mechanism of action involves the disruption of cellular processes within the target fungi, providing an effective solution for controlling fungal infections in plants. -
Fungal Inhibitor
Deoxylapachol is a significant cytotoxic compound derived from the New Zealand brown alga Landsburgia quercifolia, primarily acting as a fungal inhibitor. It exhibits notable antifungal properties, making it a valuable agent in the study of fungal infections. Additionally, deoxylapachol demonstrates anti-cancer activity, positioning it as a candidate for research applications in oncology and pathogen interaction studies. -
Fungal CYP51 Inhibitor
VT-1598 is an orally active and selective inhibitor of fungal cytochrome P450 51 (CYP51). It exhibits potent antifungal activity against Candida auris, making it a valuable tool for research into fungal infections. Additionally, VT-1598 contains an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) for click chemistry applications, facilitating the study of various biological interactions. -
Bacterial/Fungal Inhibitor
2-Methoxybenzaldehyde, also known as o-Anisaldehyde, serves as a bacterial and fungal inhibitor, with a BA50 value of 0.19 against Salmonella. This compound is utilized in the investigation of bacterial and fungal infectious diseases, providing insights into their mechanisms and potential therapeutics. Its effectiveness in hindering microbial growth makes it a valuable reagent for microbiological research. -
Antiseptic Agent; Fungal Inhibitor
Hexetidine, an orally active antiseptic agent, exhibits broad-spectrum antibacterial and antifungal activity. It is particularly effective in inhibiting fungal growth, especially when combined with IPBC. At concentrations exceeding 0.1%, hexetidine may lead to oral ulceration; however, it enhances plaque inhibition in conjunction with zinc. Additionally, its efficacy in treating purulent wounds has been demonstrated alongside ultrasound treatment. Hexetidine is a valuable candidate for research focusing on fungal infections and soft tissue purulent-inflammatory conditions. -
Serine Palmitoyltransferase Inhibitor
Lipoxamycin hemisulfate is a potent inhibitor of serine palmitoyltransferase, exhibiting an IC50 of 21 nM. This compound displays antifungal properties, making it valuable for research in the development of antifungal therapies. Its ability to modulate sphingolipid metabolism further supports its use in studies investigating underlying mechanisms of fungal infections and potential treatment strategies. -
Fungal Inhibitor
Myclobutanil is a systemic fungicide belonging to the conazole class that targets fungal sterol biosynthesis. It exhibits potent antifungal activity against a range of pathogenic fungi, making it valuable in agricultural applications. Myclobutanil is utilized in research for studying fungal resistance mechanisms and evaluating the efficacy of fungicides in crop protection. -
Fungal Inhibitor
Terconazole is a broad-spectrum antifungal agent that targets fungal cell membrane synthesis. It exhibits significant activity against various Candida species, making it effective in treating vaginal yeast infections. This compound is used in research applications to study antifungal mechanisms and drug resistance in pathogenic fungi. -
ASADH Inhibitor
Naphthalene-2,3-Dicarboxaldehyde functions as a potent inhibitor of Aspergillus nidulans succinate semialdehyde dehydrogenase (ASADH), with a reported inhibition constant (Ki) of 45 μM. Its biological activity extends to inhibiting the growth of Candida albicans strain CAF2-1, exhibiting an IC50 of 58.2 μM and a minimum inhibitory concentration (MIC) of 12 μg/mL. This compound is valuable for research applications focused on antifungal mechanisms and metabolic pathway studies involving ASADH. -
β-1,3-glucan Inhibitor
Ibrexafungerp citrate is a potent β-1,3-glucan synthesis inhibitor with promising antifungal properties. This compound demonstrates efficacy against a range of fungal infections, specifically targeting Candida and Aspergillus species. Ibrexafungerp citrate is currently under investigation for its therapeutic potential in the treatment of these serious infections. -
Fungal Inhibitor
Paclobutrazol is a triazole-based compound that functions primarily as a fungal inhibitor by disrupting the biosynthesis of gibberellins. Its antifungal properties make it useful in investigating plant-pathogen interactions and enhancing plant resilience. Additionally, Paclobutrazol can suppress abscisic acid synthesis and promote chilling tolerance in various plant species, supporting research into plant stress responses and growth regulation. -
Histone Acetyltransferase Inhibitor
Rtt109 inhibitor 1 is a potent inhibitor of the histone acetyltransferase Rtt109, functioning through a tight-binding, uncompetitive mechanism. This compound demonstrates significant antifungal activity by specifically targeting acetylation at the H3K56 site. Rtt109 inhibitor 1 is suitable for research applications focused on histone modifications and their roles in fungal pathogenesis. -
HDM Inhibitor
HDM-IN-1 is a potent inhibitor of histone demethylases (HDM), specifically targeting H3K27me3 methylation in fungal pathogens such as Cryptococcus neoformans and Candida auris, with IC50 values of 134 nM and 12 nM, respectively. This compound demonstrates significant antifungal activity, achieving MIC80 values between 0.5-2 μg/mL by disrupting biofilm and capsule formation. In vivo studies in an ICR mouse model further confirm its efficacy as an antifungal agent. HDM-IN-1 is a valuable tool for research on histone modifications and their implications in fungal virulence and drug resistance. -
Bacterial Inhibitor
Enoxacin is a fluoroquinolone antibacterial that primarily targets bacterial DNA gyrase and topoisomerase IV, with reported IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. It exhibits strong inhibitory activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin acts as a miRNA processing activator, facilitating siRNA-mediated mRNA degradation and promoting the biogenesis of endogenous miRNAs. Notably, Enoxacin serves as a cancer-specific growth inhibitor through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing, making it valuable for research in bacterial inhibition and cancer biology. -
Bacterial Inhibitor
Roxithromycin is a semi-synthetic macrolide antibiotic that exerts its antibacterial effects by inhibiting protein biosynthesis at the elongation step through binding to the 50S subunit of the bacterial ribosome. This compound demonstrates broad biological activity, including antimicrobial, antiproliferative, and anti-inflammatory properties. Additionally, Roxithromycin has been shown to inhibit tumor vasculature and alleviate lung injury, making it a valuable reagent for research applications in infectious disease, cancer therapy, and respiratory health. -
Squalene Epoxidase Inhibitor
Liranaftate is a potent squalene epoxidase inhibitor exhibiting anti-fungal properties. It is primarily utilized in research focusing on dermatophyte infections. Additionally, Liranaftate has been shown to suppress the fungal element-mediated production of interleukin-8 (IL-8) and modulate inflammatory responses, making it valuable for studies involving inflammatory pathways in fungal infections. -
Fungal Inhibitor
Pseudolaric Acid C is a bioactive diterpenoid derived from the root bark of Pseudolarix amabilis, primarily acting as a fungal inhibitor. It exhibits significant antifungal activity, making it a valuable tool for research focused on fungal pathogenesis and the development of antifungal therapies. Its ability to disrupt fungal growth positions it as an important compound in the study of mycology and related fields. -
Fungal Inhibitor
5-Hydroxymethylfurfural is a furan derivative that serves as a potent fungal inhibitor. It exhibits anti-yeast activity by suppressing growth and fermentation under stress conditions, making it valuable for studies related to microbial resistance and fermentation processes. This compound is utilized in research focused on food preservation and biotechnological applications. -
Fungal Inhibitor
Hecogenin is a steroid saponin derived from Agave sisalana, known for its selective inhibition of human UDP-glucuronosyltransferases. It exhibits a diverse range of biological activities, particularly as a potent antifungal agent, while also demonstrating anti-inflammatory and gastroprotective properties. Hecogenin is of interest in pharmacological research for its potential therapeutic applications in treating fungal infections and inflammatory conditions. -
Bacterial Inhibitor
Benzoic acid is an aromatic carboxylic acid that functions as a bacterial inhibitor. It demonstrates significant antimicrobial activity by inhibiting the growth of bacteria and fungi, making it an effective preservative. Benzoic acid is widely utilized in food, beverages, cosmetics, and various research applications to study microbial growth inhibition and preservation techniques. -
Bacterial Inhibitor
Tilmicosin is a macrolide antibiotic and calcium channel antagonist that targets the bacterial ribosome's 50S subunit, effectively inhibiting protein synthesis. It possesses significant antimicrobial activity and is primarily utilized in treating respiratory diseases in livestock, including cattle, sheep, and pigs. Additionally, Tilmicosin exhibits immunomodulatory and anti-inflammatory properties, making it a valuable reagent in veterinary medicine research.
