Naphthalene-2,3-Dicarboxaldehyde functions as a potent inhibitor of Aspergillus nidulans succinate semialdehyde dehydrogenase (ASADH), with a reported inhibition constant (Ki) of 45 μM. Its biological activity extends to inhibiting the growth of Candida albicans strain CAF2-1, exhibiting an IC50 of 58.2 μM and a minimum inhibitory concentration (MIC) of 12 μg/mL. This compound is valuable for research applications focused on antifungal mechanisms and metabolic pathway studies involving ASADH.
Naphthalene-2,3-Dicarboxaldehyde functions as a potent inhibitor of Aspergillus nidulans succinate semialdehyde dehydrogenase (ASADH), with a reported inhibition constant (Ki) of 45 μM. Its biological activity extends to inhibiting the growth of Candida albicans strain CAF2-1, exhibiting an IC50 of 58.2 μM and a minimum inhibitory concentration (MIC) of 12 μg/mL. This compound is valuable for research applications focused on antifungal mechanisms and metabolic pathway studies involving ASADH.
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