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Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
Chloracetophos is a potent fungal inhibitor that targets cell processes critical for fungal growth and survival. It exhibits significant antifungal activity, making it a valuable tool for research in mycology and agricultural applications. Its effectiveness in inhibiting fungal pathogens supports studies aimed at understanding fungal resistance mechanisms and developing new antifungal strategies. -
Antimicrobial Inhibitor
Antibacterial Agent 101 (Compd 7f) is an antimicrobial inhibitor targeting both bacterial and fungal pathogens. With minimum inhibitory concentration (MIC) values ranging from 4 to 32 µg/mL, it demonstrates potent antibacterial and antifungal activity. This compound is suitable for research applications focused on developing new antimicrobial therapies. -
Chitin Deacetylase Inhibitor
CDA-IN-1 is a potent inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal activity. This compound effectively suppresses fungal growth by inhibiting fungal CDA activity, stimulating the plant immune response, and promoting the accumulation of reactive oxygen species (ROS). At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% and 74.5% against the chitin deacetylases PxCDA1 and PxCDA2 of Pseudoperonospora xanthii, respectively. CDA-IN-1 is a valuable tool for research into plant fungal disease control, particularly in studies focused on diseases such as cucurbit powdery mildew and tomato gray mold. -
Fungal Inhibitor
Oxadixyl is a fungicide that targets fungal growth by inhibiting key cellular processes. It demonstrates significant biological activity in the presence of fungi, making it useful for evaluating its effects on microbial populations during processes such as malic fermentation in winemaking. This compound is valuable for researchers investigating antifungal treatments and their implications in fermentation science. -
CYP51 Inhibitor
CYP51-IN-19 is a potent inhibitor of cytochrome P450 51 (CYP51), a critical enzyme involved in sterol biosynthesis in fungi. This compound induces the generation of reactive oxygen species (ROS), leading to significant fungicidal activity. It is primarily utilized in antifungal research and the development of therapeutic agents targeting fungal infections. -
Fungal Inhibitor
Antifungal agent 59 is a potent fungal inhibitor with minimum inhibitory concentration (MIC) values ranging from 0.01 to 1 μg/mL. This compound effectively disrupts the formation of fungal biofilms, making it a valuable tool for research in mycology and fungal pathogenesis. Its favorable safety profile further supports its application in studying antifungal mechanisms and therapeutic approaches. -
Fungal Inhibitor
Fludazonium chloride is a potent antifungal agent that targets a range of fungal pathogens. It exhibits strong inhibitory activity against both superficial and systemic fungal infections, making it suitable for therapeutic applications in mycoses treatment and prevention. This compound can be utilized in research to further understand antifungal mechanisms and develop new treatments. -
Microbial Inhibitor
Antifungal agent 38 is a heterocyclic disulfide that acts as a potent microbial inhibitor. Its primary mechanism involves inducing hyphal shrinkage and disrupting the integrity of the plasma membrane, leading to cellular damage and leakage of intracellular contents. This compound is valuable for research applications focused on antifungal and antibacterial activities, offering insights into cell membrane dynamics and potential therapeutic approaches against microbial infections. -
Antifungal Agent/HIV-1 Inhibitor
Amphotericin B methyl ester hydrochloride is a derivative of the polyene antibiotic amphotericin B, functioning primarily as an antifungal agent. This compound exhibits potent antifungal activity by binding to cholesterol in fungal cell membranes, leading to cell death. Additionally, it disrupts HIV-1 particle production and significantly inhibits HIV-1 replication, making it valuable for research in antifungal therapies and HIV treatment studies. -
Serine Palmitoyltransferase Inhibitor
Lipoxamycin is a potent serine palmitoyltransferase inhibitor, exhibiting an IC50 of 21 nM. This compound demonstrates significant antifungal activity, making it a valuable tool for studying lipid metabolism and sphingolipid biosynthesis. Lipoxamycin is applicable in research focused on fungal infections and potential avenues for therapeutic interventions targeting lipid-related pathways. -
SDH Iinhibitor
SDH-IN-5 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 3.293 μM. It exhibits significant antifungal activity, achieving an EC50 of 0.046 μg/mL against Rhizoctonia solani. In agricultural applications, SDH-IN-5 effectively inhibits the growth of R. solani in rice leaves, showcasing substantial protective and curative efficacies against this pathogen. -
Tau Aggregation Inhibitor
Nimbin is a potent tau aggregation inhibitor derived from the limonoid class of compounds found in Azadirachta. It is shown to enhance cell viability while effectively inhibiting the envelope protein of the dengue virus. Additionally, Nimbin exhibits a range of biological activities, including anti-inflammatory, antifungal, antihistamine, antiseptic, antioxidant, anticancer, and antiviral properties. This diverse activity profile makes Nimbin a valuable reagent for research in neurodegenerative diseases and viral infections. -
Fungal Inhibitor
2,4′-Dichloroacetanilide is a fungistatic agent that inhibits the growth of fungi by targeting key cellular processes. It demonstrates significant antifungal activity against Trichosporon asteroides, with a minimum inhibitory concentration (MIC) of 6.25 μg/mL. This compound is valuable for research applications involving fungal pathogenesis and the development of antifungal therapies. -
Fungal Inhibitor
Cyclo(Pro-dArg) is a potent chitinase inhibitor, primarily targeting fungal cell wall integrity. It effectively disrupts cell separation in Saccharomyces cerevisiae while having no significant impact on its overall growth. Additionally, Cyclo(Pro-dArg) inhibits the morphological transition of Candida albicans from yeast to filamentous forms, making it valuable for research in fungal biology and antifungal drug development. -
Fungal Inhibitor
4-Chlorosalicylic acid is a potent fungal inhibitor that functions primarily by inhibiting monophenolase and diphenolase activities, demonstrating IC50 values of 1.89 mM and 1.10 mM, respectively. It exhibits significant antimicrobial properties, displaying an MIC of 250 μg/mL and an MBC of 500 μg/mL against E. coli. This compound is useful in research applications focused on elucidating mechanisms of fungal and bacterial inhibition. -
Fungal Inhibitor
(E)-Coniferyl alcohol is a fungal inhibitor that acts as an intermediate in the biosynthetic pathways of eugenol, stilbenoids, and coumarin. This compound demonstrates potent activity against fungal species, making it valuable for studies focused on fungal growth inhibition. Its applications span research on plant defense mechanisms and the development of antifungal agents. -
BoNT A Inhibitor
Chaetochromin A is a fungal metabolite that acts as an inhibitor of botulinum neurotoxin serotype A (BoNT A). With an IC50 value of 24.6 μM, it demonstrates significant inhibitory effects, making it a valuable tool for research into neurotoxicology and the mechanistic pathways of neurotoxin action. Its role in understanding BoNT A interactions provides insights for potential therapeutic applications. -
Fungal Inhibitor
Isopyrazam serves as a potent fungal inhibitor, demonstrating significant efficacy against various plant pathogenic fungi. Its mechanism of action enhances disease resistance in crops, making it a valuable tool in agricultural research focused on plant protection and disease management. The use of Isopyrazam can lead to improved crop yield and quality, highlighting its potential applications in agro-biological studies. -
Mpro Inhibitor/Anti-Coronaviral Agent
Polycarpine hydrochloride is a potent inhibitor of the main protease (Mpro) with an IC50 of 30 nM, making it a valuable anti-coronaviral agent. This compound, derived from Polycarpa aurata, exhibits significant antiviral properties, demonstrating effectiveness against SARS-CoV-2 Mpro and PEDV Mpro, with IC50 values of 30.0 nM and 0.12 μM respectively. It also possesses antifungal activity, positioning it as a versatile tool for research in virology and infectious diseases. -
Fungal Inhibitor
Ethyl Vanillate is a potent fungal inhibitor that primarily targets 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2), with an IC50 of 1.3 µM. This compound demonstrates significant antifungal properties, making it valuable for research focused on fungal infections and related metabolic pathways. Its ability to modulate steroid hormone activity positions Ethyl Vanillate as an important tool in studies of fungal biology and therapeutic strategies. -
Fungal Inhibitor
(S,S)-Valifenalate is an acylamino acid fungicide targeting the cell-wall synthesis of Oomycetes fungi. By disrupting the structural integrity of the cell wall, it effectively hinders the growth stages of fungal pathogens, both externally on spores and internally within plant mycelium. This compound is employed in various agricultural research applications aimed at developing strategies for fungal control and improving crop health. -
Succinate Dehydrogenase Inhibitor
Isofetamid is a potent inhibitor of succinate dehydrogenase, primarily utilized as a fungicide. It demonstrates effective control against a range of fungal pathogens, including gray mold, white mold, and powdery mildew. This compound is valuable for research related to plant fungal diseases, contributing to the understanding of fungal inhibition mechanisms and disease management strategies. -
Fungal Inhibitor
Thalifoline is an alkaloid recognized for its antifungal properties, primarily targeting fungal cell integrity. Its mode of action involves disrupting fungal growth and proliferation, making it a valuable reagent for research focused on antifungal drug development and potential therapeutic applications against fungal infections. -
Calcineurin Inhibitor
APX879 is a calcineurin inhibitor that selectively targets fungal cells, exhibiting reduced immunosuppressive effects and lower toxicity compared to traditional agents. As a C22-modified analog of FK506, APX879 retains broad-spectrum antifungal activity, making it a valuable tool for studying fungal pathogenesis and the immune response. It holds potential applications in antifungal drug development and research focused on fungal infections. -
Fungal Inhibitor
Saperconazole is a broad-spectrum antifungal triazole that primarily targets fungal growth by inhibiting 14α-demethylase, an enzyme essential for ergosterol biosynthesis. It exhibits potent activity against Aspergillus species, with a minimum inhibitory concentration (MIC90) of 0.19 mg/L. Saperconazole is utilized in research applications involving antifungal efficacy and mechanistic studies of fungal pathogens. -
CHS Inhibitor
Chitin Synthase Inhibitor 4 is a selective inhibitor of chitin synthase (CHS), functioning primarily by disrupting chitin biosynthesis in fungal pathogens. This compound demonstrates significant fungicidal activity, making it a promising candidate for agricultural applications aimed at controlling fungal infections. Its mechanism supports research into chitin synthase-targeted approaches in crop protection and fungal biology. -
Fungal Inhibitor
Kakuol is a naturally derived compound that acts as a fungal inhibitor, targeting fungal cell growth and proliferation. Exhibiting potent antifungal activity, Kakuol is valuable for research applications involving the investigation of fungal infections and the development of antifungal therapies. Its mechanism of action provides insights into novel approaches for combating fungal pathogens. -
SDH Inhibitor
SDH-IN-2 is a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 value of 0.55 μg/mL, demonstrating strong antifungal activity against phytopathogenic fungi, with an average EC50 range of 3.82-9.81 μg/mL. This compound also features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its dual role as an SDH inhibitor and antifungal agent makes SDH-IN-2 a valuable tool for biochemical research and drug development studies focused on metabolic pathways and fungal diseases. -
Fungal Inhibitor
SCH 51048 is a potent fungal inhibitor that generates active metabolites with demonstrated antifungal properties. Research studies have shown that these metabolites exhibit enhanced activity, making SCH 51048 a valuable compound for investigating antifungal mechanisms and evaluating therapeutic options in fungal infections. This compound serves as a useful tool in the study of fungal biology and the development of new antifungal agents. -
Fungal Inhibitor
Picropodophyllone is an aryltetralin lignan that functions as a fungal inhibitor. This compound exhibits significant antifungal activity, making it a valuable tool for research applications in mycology and the study of fungal pathogenesis. Its isolation from the leaves of Podophyllum hexandrum underlines its natural origin and potential therapeutic implications in combating fungal infections. -
Fungal Inhibitor
L-4-Oxalysine hydrochloride is a naturally occurring compound that acts as a fungal inhibitor. Traditionally isolated from the culture media of Streptomyces roseovirdofuscus, this reagent demonstrates significant antitumor activity. It is utilized in research studies focused on fungal pathogenesis and potential therapeutic applications in oncology. -
Fungal Inhibitor
Exalamide is a potent antifungal agent targeting fungal growth through the inhibition of specific enzymes involved in cellular processes. This compound exhibits significant biological activity against a range of fungal pathogens, making it a valuable tool for research on fungal infections and related diseases. Its application is suited for studies focused on antifungal mechanisms and the development of new therapeutic strategies. -
Fungal Inhibitor
2-Butylbenzo[d]isothiazol-3(2H)-one is a fungal inhibitor that displays significant antibacterial and antifungal activity. This compound is utilized in agricultural applications to safeguard crops against pathogenic fungi, making it an essential ingredient in pesticides. Additionally, it is incorporated into coatings to deter mold and algae growth. Its preservative properties also make it valuable in personal care formulations, helping to extend product shelf life. -
Fungal Inhibitor
2-Ethylnaphthalene is an alkyl-substituted polyaromatic compound that serves as a fungal inhibitor. It has been shown to negatively correlate with the abundance of Glomus species within arbuscular mycorrhizal fungi communities. This property makes 2-Ethylnaphthalene a valuable reagent for investigating fungal interactions and dynamics in various biological research applications. -
Bacterial Inhibitor
N-Butanoyl-L-homoserine lactone (C4-HSL) is a bacterial inhibitor that functions as a signaling molecule in quorum sensing. This compound demonstrates significant antibacterial activity and effectively disrupts biofilm formation, particularly in Pseudomonas aeruginosa. Research applications include studying bacterial communication and developing strategies to combat antibiotic-resistant infections through targeted inhibition of quorum sensing pathways. -
Bacterial Inhibitor
2-Ethyl-6-methylphenol is an alkylphenol with significant antibacterial properties. This compound has demonstrated efficacy in inhibiting bacterial growth and exhibits potential insecticidal activity, making it a valuable tool in microbiological research and pest control studies. Its role as a bacterial inhibitor can facilitate investigations into microbial resistance and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Upleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Bacterial Inhibitor
Gepotidacin (S enantiomer) is a potent bacterial inhibitor that targets bacterial DNA replication and transcription processes. This compound exhibits effective antimicrobial activity against a range of gram-positive and gram-negative bacteria, making it valuable for research in infectious disease models. Its mechanism of action involves inhibition of bacterial topoisomerase, contributing to its bactericidal effects. Gepotidacin (S enantiomer) is primarily applied in studies focused on antibiotic resistance and the development of new therapeutic strategies. -
Bacterial Inhibitor
Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics. -
Bacterial Inhibitor
Ganoderol A is a terpenoid derived from Ganoderma lucidum that acts as a bacterial inhibitor. It demonstrates antimicrobial properties and plays a role in inhibiting the cholesterol synthesis pathway. Additionally, Ganoderol A exhibits significant anti-inflammatory effects and provides protection against ultraviolet A (UVA) damage, making it valuable for research in microbial resistance and skin protection strategies. -
Bacterial Inhibitor
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol with antibacterial properties. It functions by inhibiting bacterial growth, making it valuable for research in antimicrobial applications. Its isolation from Ailanthus altissima Swingle highlights its natural origins and potential utility in studies exploring microbial resistance and antibiotic development. -
Bacterial Inhibitor
Primin is a natural product that acts as a bacterial inhibitor, primarily targeting microbial growth. Isolated from the trichomes of Primula obconica, it exhibits significant antimicrobial and antitumor activities. This compound is valuable in research focused on developing antibacterial agents and cancer therapeutics. Its unique properties make it a useful tool for investigating bactericidal mechanisms and potential therapeutic applications. -
Bacterial Inhibitor
Cowaxanthone B is a xanthone compound derived from the fruits of Garcinia cowa, primarily targeting bacterial pathways. This agent exhibits moderate antibacterial activity and may be utilized in research contexts aimed at understanding bacterial inhibition mechanisms. Its potential applications include the study of antimicrobial resistance and the development of new antibacterial agents. -
Bacterial Inhibitor
Parasin I is a 19-amino acid peptide derived from histone H2A, exhibiting significant antimicrobial properties primarily against bacterial pathogens. This peptide serves as a bacterial inhibitor, making it a valuable tool for research focused on microbial resistance and the development of new antimicrobial agents. Its unique mechanism of action may provide insights for therapeutic applications in infectious disease management. -
Bacterial Inhibitor
Cinnamylideneacetic acid is a bacterial inhibitor that engages in a photoinduced [2+2] cycloaddition reaction. This compound exhibits significant antibacterial activity, making it a valuable tool for research on bacterial resistance mechanisms and the development of new antimicrobial agents. Its photoresponsive properties allow for the exploration of light-activated therapies in microbial systems. -
Bacterial Inhibitor
Triclosan-methyl is a transformation product of triclosan, functioning primarily as a bacterial inhibitor. It exhibits significant antimicrobial activity, making it relevant for applications in assessing bacterial resistance and efficacy of antimicrobial compounds. This compound is commonly utilized in research related to personal care products and their environmental impact, particularly in evaluating the persistence and degradation of antibacterial agents. -
Bacterial Inhibitor
(+)-Viroallosecurinine is a potent antibacterial alkaloid that acts as a bacterial inhibitor. It demonstrates significant antimicrobial activity, with a minimum inhibitory concentration (MIC) of 0.48 μg/mL against Pseudomonas aeruginosa and Staphylococcus aureus. This compound is suitable for research applications focused on understanding bacterial resistance and developing novel antibacterial agents. -
Bacterial Inhibitor
Ribocil-C (R enantiomer) is a selective inhibitor targeting bacterial riboflavin riboswitches. This compound disrupts riboflavin biosynthesis by binding to specific RNA structures, effectively inhibiting bacterial growth. It is useful in research applications focusing on bacterial gene regulation and the development of novel antimicrobial strategies. -
Bacterial Inhibitor
Chloroneb is a bacterial inhibitor with fungicidal properties that effectively protects plants. It is utilized in analytical applications for the detection of organochlorine pesticide residues, demonstrating excellent selectivity, stability, and reproducibility. Chloroneb has been successfully applied in the analysis of various samples, including licorice, cucumber, river water, and soil, providing reliable results for environmental monitoring and agricultural research. -
Bacterial Inhibitor
Amifloxacin is a synthetic antibacterial agent belonging to the quinolone class, primarily targeting bacterial DNA gyrase and topoisomerase IV. This compound exhibits potent bactericidal activity against a broad spectrum of gram-negative and gram-positive bacteria. It is commonly utilized in research applications for studying bacterial infections and evaluating the efficacy of antibiotic treatments.
