CDA-IN-1 is a potent inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal activity. This compound effectively suppresses fungal growth by inhibiting fungal CDA activity, stimulating the plant immune response, and promoting the accumulation of reactive oxygen species (ROS). At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% and 74.5% against the chitin deacetylases PxCDA1 and PxCDA2 of Pseudoperonospora xanthii, respectively. CDA-IN-1 is a valuable tool for research into plant fungal disease control, particularly in studies focused on diseases such as cucurbit powdery mildew and tomato gray mold.
CDA-IN-1 is a potent inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal activity. This compound effectively suppresses fungal growth by inhibiting fungal CDA activity, stimulating the plant immune response, and promoting the accumulation of reactive oxygen species (ROS). At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% and 74.5% against the chitin deacetylases PxCDA1 and PxCDA2 of Pseudoperonospora xanthii, respectively. CDA-IN-1 is a valuable tool for research into plant fungal disease control, particularly in studies focused on diseases such as cucurbit powdery mildew and tomato gray mold.
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