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Upleganan

Catalog No.: A48429
Bacterial Inhibitor
Upleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies.
Upleganan 2407717-17-1 Bacterial Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUpleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies.
Product Information
Catalog NumA48429
FormulaC52H82ClN15O12
Molecular Weight1144.75
CAS Number2407717-17-1
SMILESO=C(N[C@@H](CC(C)C)C(N[C@@H](CCN)C(N[C@@H](CCN)C(N1)=O)=O)=O)[C@H](NC([C@H](CCN)NC([C@H](CCNC([C@@H]1[C@H](O)C)=O)NC([C@H](CN)NC([C@@H](NC(C[C@@H](C2=CC=CC(Cl)=C2)CN)=O)[C@H](O)C)=O)=O)=O)=O)CC3=CC=CC=C3
SynonymsSPR206
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Microbiology > Antifection > Bacterial