Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
2,6-Dichloro bisphenol A-d12 is a stable isotope-labeled compound derived from 2,6-Dichloro bisphenol A. This deuterium-labeled variant is utilized in trace analysis and quantification in chemical research, particularly in pharmacokinetic studies and environmental monitoring. Its stable isotope nature enhances the sensitivity and accuracy of analytical techniques, making it valuable for studies investigating the metabolism and distribution of chlorinated bisphenols. -
Stable Isotope
Benzothioamide-d5 is a stable isotope-labeled compound derived from Benzothioamide. This deuterated derivative is primarily utilized in various analytical and biochemical studies, including tracing experiments and metabolic labeling. The incorporation of deuterium improves the sensitivity and accuracy of mass spectrometry analyses, making it a valuable tool for researchers investigating the pharmacokinetics and metabolism of thiamide compounds. -
Stable Isotope
Benz[a]anthracene-7-methanol-13C is a stable isotope-labeled compound derived from benz[a]anthracene, featuring a methanol group at the 7-position. This reagent is utilized primarily in metabolic studies and environmental research to trace the behavior and metabolism of polycyclic aromatic hydrocarbons (PAHs). Its isotopic labeling enables precise tracking in various biological systems, contributing to a better understanding of PAH interactions and effects. -
Stable Isotope
(4-Fluorophenyl)methanol-d6 is a stable isotope-labeled compound derived from (4-Fluorophenyl)methanol. This deuterated reagent serves as a valuable tool in various analytical chemistry applications, including NMR spectroscopy and trace analysis of organic compounds. Its unique isotopic labeling enhances detection sensitivity, making it suitable for metabolic studies and the investigation of biological pathways. -
Drug Impurity
Hydrocortisone impurity 1, also known as 6β-Hydroxy cortisol, is a structural impurity derived from Hydrocortisone. This compound is relevant in quality control and analytical studies focused on pharmaceuticals, particularly in the evaluation of drug purity and validation of analytical methods. Its role in understanding the stability and degradation pathways of corticosteroid formulations is crucial for ensuring the safety and efficacy of therapeutic agents. -
Drug Impurity
Hydrocortisone acetate impurity 2 is a chemically defined impurity derived from hydrocortisone acetate. This compound serves as an important reference standard in the assessment of drug quality and formulation. Its examination is critical for understanding the impurity profile during hydrocortisone acetate synthesis and ensuring the safety and efficacy of pharmaceutical products. This impurity is also valuable for analytical development and regulatory compliance in the pharmaceutical industry. -
Butin Enantiomer
(-)-Butin is the active enantiomer of Butin, a flavonoid derived from the heartwood of Dalbergia odorifera. This compound exhibits significant antioxidant, antiplatelet, and anti-inflammatory properties, making it valuable for research in cardiovascular health and inflammatory diseases. Its biological activities position (-)-Butin as a potential lead compound for the development of therapeutic agents targeting oxidative stress and platelet aggregation. -
Terpenoid
(S)-Campesterol, a terpenoid and phytosterol, is primarily found in the leaves of Plumeria rubra L., forma acutifolia (Ait) Woodson. This compound plays a critical role in membrane structure and function due to its ability to modulate lipid dynamics. (S)-Campesterol is widely used in research applications focused on plant physiology, lipid metabolism, and the study of cholesterol metabolism in humans and other organisms. -
Isomer of 4β-Hydroxycholesterol
4α-Hydroxycholesterol is an isomer of 4β-Hydroxycholesterol, known for its role in modulating biological activities within cells. This compound exhibits a slight impact on the integrity of lysosomal membranes, particularly in primary oligodendrocyte cultures derived from mice. Its unique properties make it valuable for research applications in cellular biology and studies related to lipid metabolism and neurobiology. -
Anticancer Agent
(Rac)-Hydnocarpin is a flavonoid compound derived from Hydnocarpus anthelminthica, exerting its anticancer effects through cytotoxic activity against cancer cells. This agent is primarily used in research exploring novel cancer therapies and mechanisms of action. Its potential for developing anticancer strategies makes it a valuable tool in oncology studies. -
Isomer
(R)-Vitamin D2 is the isomer of Vitamin D2, serving as an essential experimental control in biochemical research. As a form of Ergocalciferol derived from plant sources, it plays a crucial role in supplementing Vitamin D levels. This compound is primarily utilized in studies involving calcium regulation, bone health, and immunomodulation, facilitating research into its biological effects and therapeutic potential. -
Natural Product
(+)-Leucocyanidin is a natural product known for its anti-ulcerogenic properties. Derived from Litchi chinensis, this compound exhibits a significant protective effect against aspirin-induced gastric erosions in rat models. Its biological activity supports research applications in gastrointestinal protection and therapeutic development for ulcer-related conditions. -
Butin R Enantiomer
(+)-Butin is the R-enantiomer of butin, a bioactive flavonoid derived from the heartwood of Dalbergia cocos. This compound demonstrates significant antioxidant, antiplatelet, and anti-inflammatory properties. Due to its diverse biological activities, (+)-Butin is valuable for research applications in studying oxidative stress, cardiovascular health, and inflammatory processes. -
Myrrhterpenoid O Enantiomer
Myrrhterpenoid O enantiomer is a specific enantiomer of the sesquiterpenoid compound Myrrhterpenoid O, which demonstrates significant inhibitory activity against Plasmodium falciparum, with an IC50 value of 21 μM. This compound is primarily utilized in research focused on antimalarial drug discovery and the exploration of natural products' therapeutic potential. Its efficacy against malaria renders it a valuable tool for studies aimed at understanding and combating this infectious disease. -
Ketone monoester (S,S)-enantiomer
(S,S)-Ketone monoester is the (S,S)-enantiomer of Ketone monoester, functioning as a metabolic regulator. This compound elevates levels of acetoacetate (AcAc) and acetone, facilitating sustained ketosis while significantly delaying seizures associated with central nervous system oxygen toxicity (CNS-OT). It serves as a valuable reagent for researchers investigating metabolic pathways and neuroprotective strategies. -
Racemic Mixture of 5-HETE Lactone
(±)5-HETE lactone is a racemic mixture of 5-HETE lactone, a metabolite derived from the enzymatic conversion of arachidonic acid. This compound serves as a substrate for paraoxonase-1 (PON1) and plays a role in B cell activation studies. Its utility in biochemical research extends to exploring the functions and signaling pathways associated with B cells in immune responses. -
Saponin
Vinaginsenoside R2 is an ocotillol-type saponin derived from Panax vietnamensis. It demonstrates cytotoxic effects on mouse peritoneal macrophages, indicating its potential utility in studying immune responses and inflammatory diseases. Additionally, Vinaginsenoside R2 can be metabolized by intestinal microbiota into Pseudoginsenoside RT4 and Ocotillol, suggesting further avenues for research into its biochemical pathways and therapeutic implications. -
Biochemical Reagent
NAD(P)H-Nitrate reductase is a biochemical reagent derived from Aspergillus niger, facilitating the reduction of nitrate to nitrite through a two-electron transfer mechanism. This enzyme utilizes NADPH as an electron donor, functioning as a bispecific NAD(P)H:Nitrate reductase. It is essential for studies involving nitrogen metabolism, enzymatic activity assays, and the exploration of metabolic pathways in both plant and microbial systems. -
Drug Isomer
(±)5-HEPE is a drug isomer produced through the non-enzymatic oxidation of eicosapentaenoic acid (EPA), comprising equal amounts of the 5(S) and 5(R) isomers. The biological activity of (±)5-HEPE is primarily attributed to the 5(S) isomer, which plays a role in various mammalian biological systems. In human and bovine neutrophils, as well as human eosinophils, EPA is metabolized to 5-HEPE, which can further be converted to 5-oxoEPE and LTB5. It is important to note that the 5-series metabolites of EPA exhibit significantly reduced biological effects in comparison to metabolites derived from arachidonic acid. -
Geometric Isomer of Piperine
Isopiperine is the geometric isomer of piperine, derived from black pepper. This compound exhibits significant antifeedant activity against Spodoptera litura, with an effective dose (ED50) of 0.058 μmol/cm². Isopiperine is valuable for research in pest control and plant defense mechanisms, providing insight into ecological interactions and potential agricultural applications. -
diastereoisomer;
6-epi-COTC is a diastereoisomer derived from a Streptomyces metabolite, exhibiting notable anti-cancer activity. This compound is utilized in research focused on understanding the mechanisms of cancer cell proliferation and apoptosis. Its unique structural properties make it valuable in the exploration of therapeutic approaches to combat various types of cancer. -
Natural Product
Cimicifugic acid N is a natural product known to be the cis-isomer of Cimicifugic acid G, isolated from the aerial parts of Cimicifuga simplex and Cimicifuga japonica. This compound exhibits notable biological activity, contributing to research in phytochemistry and pharmacology. Its unique structural features and potential bioactivity make it a valuable reagent for investigations into traditional medicine and the therapeutic properties of plant-derived compounds. -
Natural Product
(+)-Vestitol is a natural product isolated from the leaves of Trifolium arvense. This enantiomer exhibits potential biological activity relevant for research into its pharmacological properties. Studies suggest that (+)-Vestitol may play a role in various biological pathways, making it a valuable reagent for investigations in natural product chemistry and therapeutic applications. -
Alkaloid
(±)-Pellotine hydrochloride is an alkaloid that targets neurotransmitter pathways. This compound has been shown to decrease locomotor activity and reduce rapid eye movement (REM) sleep in murine models. Research applications include studies on sleep regulation and the effects of alkaloids on behavior in animal studies. -
Natural Product
Cis-Miyabenol C is a natural product isoform of the resveratrol trimer Miyabenol C, isolated from grape herbs. This compound exhibits significant inhibition of β-amyloid (Aβ) and amyloid β precursor protein (APP) in models related to Alzheimer's disease. Additionally, cis-Miyabenol C inhibits β-secretase activity without altering the protein levels of β-secretase BACE1. It is a valuable reagent for research aimed at understanding and developing therapeutic strategies for Alzheimer's disease. -
Natural Dye
Carmine is a natural red dye derived from the dried females of the cochineal insect, Dactylopius coccus var. Costa. Recognized for its use as a food additive, carmine exhibits distinct biological activity, inducing both immediate hypersensitivity and delayed systemic responses, often with cutaneous manifestations. This compound is valuable in research applications focusing on allergenic responses and the study of natural colorants in various biological systems. -
Fluorescent Dye
SBB-Analogue (GL13) Biotin is a fluorescent dye derived from Sudan Black B, conjugated to biotin. This reagent specifically detects senescent cells, overcoming the false positive staining issues associated with SA-β-gal due to factors such as serum starvation and cell confluency. SBB-Analogue (GL13) Biotin is suitable for applications in flow cytometry and immunofluorescence analysis, providing a reliable tool for studying cellular senescence in various biological contexts. -
Angucycline Antibiotic
Urdamycin A is an angucycline antibiotic derived from Streptomyces fradiae. Notably, it functions as an orange pH indicator, shifting to ultramarine blue at pH 7.7. Urdamycin A exhibits significant anticancer activity, showing IC50 values of 2.4 μg/mL in proliferation assays and 0.55 μg/mL in stem cell assays. This compound is relevant for research applications in cancer biology and antibiotic activity studies. -
Fluorescent Dye
BP Fluor 488 DBCO is a fluorescent dye designed for use in copper-free Click Chemistry reactions, specifically targeting azide-containing biomolecules such as antibodies, proteins, and peptides. It exhibits strong fluorescent properties, with an excitation peak at 499 nm and an emission peak at 520 nm, making it suitable for applications in microscopy and flow cytometry. This dye is derived from a pure 5-sulfonated rhodamine molecule, ensuring consistent performance and minimizing lot-to-lot variability caused by isomer ratio differences. -
Natural Product
Antheraxanthin is a carotenoid with photoprotective properties primarily derived from chromophyte algae. This natural product plays a crucial role in light-harvesting and photoprotection, helping to dissipate excess energy and mitigate oxidative stress in photosynthetic organisms. Antheraxanthin is widely used in research applications focused on plant biology, photoprotection mechanisms, and the study of carotenoid biosynthesis. -
Monosaccharide
D-Glucose, a naturally occurring monosaccharide, serves as a fundamental component of cellular metabolism. As the most abundant form of glucose, it plays a vital role in energy production and is essential for various biochemical pathways. D-Glucose is also involved in signaling mechanisms related to cellular metabolic status and responses to biotic or abiotic stress, making it valuable in metabolic research and cellular studies. -
Contrast Agent
Meglumine, an amino sugar derived from sorbitol, serves as a contrast agent primarily through its role as a solvent and stabilizing agent in iodinated compounds. It exhibits anti-inflammatory and antitumor properties, making it valuable in various biomedical applications. Meglumine is commonly employed as an excipient in pharmaceutical formulations, enhancing the efficacy of active molecules in imaging studies and therapies. -
LOXL2 Inhibitor, EMT Inhibitor
Escin IA is a selective LOXL2 inhibitor that targets epithelial-mesenchymal transition (EMT), effectively suppressing cell invasion, migration, and metastasis in breast cancer models. Derived from the Aesculus chinensis Bunge fruit saponin fraction, it is identified as a key component in mitigating triple-negative breast cancer metastasis. Additionally, Escin IA has potential applications in studying acute inflammation and ethanol-induced gastric mucosal lesions. -
Saponin Compound
Escin IB is a saponin compound derived from the seeds and skin of the horse chestnut (Aesculus hippocastanum). It is known to inhibit pancreatic lipase activity, making it useful in studying lipid metabolism and obesity research. Additionally, Escin IB has potential applications in various studies related to gastrointestinal disorders and metabolic pathways. -
HIV Inhibitor
Sennoside A is an anthraquinone glycoside derived from the senna plant (Cassia angustifolia) that exhibits inhibitory activity against HIV-1. This compound demonstrates an IC50 value of 3.8 μM in preventing HIV-1 replication and effectively inhibits HIV-1 reverse transcriptase-related DNA polymerase and ribonuclease H, with IC50 values of 1.9 μM and 5.3 μM, respectively. Sennoside A serves as a valuable tool in antiviral research, particularly in studies of HIV-1 replication mechanisms and potential therapeutic interventions. -
Bacterial Inhibitor
Allicin (diallyl thiosulfinate) is a potent bacterial inhibitor derived from garlic extracts, primarily responsible for the antimicrobial properties of garlic. It demonstrates significant antimicrobial activity against a wide range of microorganisms, including antibiotic-resistant strains, making it a valuable reagent for research in microbiology and pharmacology. Allicin is commonly utilized in studies investigating natural antibacterial compounds and their mechanisms of action. -
Anti-inflammatory Agent
Saikosaponin A is an anti-inflammatory agent primarily derived from Bupleurum chinense. It effectively regulates lipid metabolism and promotes cholesterol efflux, making it relevant in early atherosclerosis research. Furthermore, Saikosaponin A acts as a potential agonist of peroxisome proliferator-activated receptor γ (PPAR-γ), significantly enhancing its expression. This compound is particularly useful in studies related to hyperlipidemic pancreatitis. -
Alkaloid
Cephalotaxine is a naturally occurring alkaloid derived from Cephalotaxus fortunei, known for its antileukemic and antiviral properties. This compound exhibits significant anti-Zika virus (ZIKV) activity, making it a valuable tool in research focused on viral infections and cancer therapeutics. Its unique biological activities position Cephalotaxine as a potential candidate for further investigation in medicinal chemistry and therapeutic applications. -
Antibiofilm Formation
Usaramine is a pyrrolizidine alkaloid derived from the seeds of Crotalaria pallida, primarily targeting antibiofilm formation. It exhibits significant inhibitory effects against biofilm development in Staphylococcus epidermidis, reducing biofilm formation by over 50% while maintaining bacterial viability. This compound is valuable for research applications focused on biofilm-related infections and antimicrobial resistance. -
Biochemical Assay Reagent
Driselase, derived from Basidiomycetes sp., is a complex mixture of wall-digesting enzymes primarily used as a biochemical assay reagent. It effectively promotes protoplast formation in fungi when combined with lyase, facilitating advanced studies in fungal physiology and genetics. Driselase demonstrates exceptional potency in polysaccharide digestion, enhancing both tensile and indentation compliances without inducing wall creep, even after extended digestion periods. This makes it an invaluable tool for researchers investigating cell wall dynamics and protoplast isolation. -
Antitumor Agent
Chlorotoxin is a 36 amino acid peptide derived from the venom of the Israeli scorpion, Leiurus quinquestriatus, known for its antitumor properties. By functioning as a chloride channel blocker, Chlorotoxin inhibits the proliferation of cancer cells and modulates ion channel activity. This compound is valuable for cancer research, particularly in studies investigating tumor biology and the development of targeted therapies. -
PLA2 Inhibitor
trans-Benzylideneacetone is a selective inhibitor of phospholipase A2 (PLA2) that demonstrates immunosuppressive activity. Derived from the entomopathogenic bacterium Xenorhabdus nematophila, this compound has significant implications for research in inflammation and immune response modulation. Its ability to inhibit PLA2 makes it a valuable tool in studies focusing on phospholipid metabolism and related biological pathways. -
Anti-allergic Agent
Cimifugin is an anti-allergic agent derived from the herb Cimicifuga racemosa. It exhibits properties that suppress allergic inflammation by modulating key factors derived from epithelial cells and regulating tight junction integrity. Additionally, Cimifugin demonstrates a capacity to reduce the migration and chemotaxis of RAW264.7 macrophage cells while inhibiting the release of inflammatory mediators and the activation of MAPK and NF-κB signaling pathways triggered by LPS. This compound is valuable for research into mechanisms of allergic responses and inflammatory conditions. -
HBV Inhibitor
Catalpol, an iridoid glycoside derived from Rehmannia glutinosa, primarily targets hepatitis B virus (HBV) inhibition. It exhibits a broad range of biological activities including neuroprotection, hypoglycemic effects, anti-inflammatory properties, and antioxidant effects. Additionally, Catalpol demonstrates potential in anti-cancer and anti-spasmodic applications, making it valuable for various research contexts focusing on viral infections and related therapeutic interventions. -
Tyrosinase Inhibitor
Benzylacetone is a potent and reversible inhibitor of tyrosinase, targeting both monophenolase and diphenolase activities with IC50 values of 2.8 mM and 0.6 mM, respectively. This aromatic compound, derived from agarwood, is primarily used in research applications related to pigmentation and enzyme inhibition. Additionally, benzylacetone has been observed to influence appetite and locomotor activity, making it relevant for studies in metabolic processes. -
Natural Product
2-Pentylfuran is a natural product derived from steam volatile oils extracted from potatoes. This compound functions as a phytohormone, playing a critical role in plant growth and development. Its biological activity includes potential use in plant research, specifically in studies related to hormone signaling pathways and environmental responses. - Neryl acetate is an ester derived from the distillation of citrus oils, primarily exhibiting its role as a fragrance compound. This compound displays biological activity by acting as an antimicrobial agent and has applications in food flavoring, cosmetics, and perfumery. Its potential use in research includes studying its effects on microbial growth and its role in enhancing sensory properties in various formulations.
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Phenol
4-Methoxybenzaldehyde, also known as p-anisaldehyde, is a phenolic compound recognized for its aromatic properties. This compound exhibits various biological activities, including potential neurotoxicity, with documented effects on mortality and host-seeking behaviors in certain organisms. 4-Methoxybenzaldehyde is frequently utilized in chemical research for its role in studying plant interactions and assessing its ecological implications. -
Anticancer Agent
Heterophyllin B is a cyclic peptide extracted from Pseudostellaria heterophylla, exhibiting significant anticancer properties. It has demonstrated potential in the treatment of esophageal cancer by targeting specific cellular mechanisms involved in tumor progression. This compound serves as a promising candidate for further research and development in cancer therapeutics. -
Triterpenoid Saponin
Polygalasaponin V is a triterpenoid saponin derived from the aerial parts of Polygala japonica. This compound exhibits significant biological activities, including expectorant, anti-inflammatory, antibacterial, and antidepressant effects. It is utilized in research applications exploring traditional medicinal uses and therapeutic potential for various inflammatory and infectious diseases.
