Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me is a disaccharide linker that serves as a substrate for the endo-glycosidase Endo-S2. This compound facilitates the site-specific modification of antibodies by enabling the direct transfer to the conserved N-glycosylation site at Asn297 within the Fc domain. Its utility in the synthesis of antibody-drug conjugates (ADCs) supports a range of research applications, particularly in the fields of immunotherapy and biomolecular engineering.
Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me is a disaccharide linker that serves as a substrate for the endo-glycosidase Endo-S2. This compound facilitates the site-specific modification of antibodies by enabling the direct transfer to the conserved N-glycosylation site at Asn297 within the Fc domain. Its utility in the synthesis of antibody-drug conjugates (ADCs) supports a range of research applications, particularly in the fields of immunotherapy and biomolecular engineering.
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