Catalog No.
Product Name
Application
Product Information
Citations
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Biochemical Assay Reagent
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid primarily employed as a biochemical assay reagent. It features a positively charged ammonium head group paired with two hydrophobic tails, facilitating the formation of liposomes and lipid-based nanoparticles for efficient gene delivery. This compound is instrumental in gene therapy and vaccine development, enhancing cellular uptake of nucleic acids. Additionally, due to its surfactant properties, it finds applications in various formulations, although caution is advised due to potential toxicity and irritative effects. -
Biochemical Assay Reagent
DMPG sodium is a biochemical assay reagent functioning primarily as a liposome carrier. Its primary application involves encapsulating 6-shogaol, a compound known for its anticancer properties, enhancing its delivery and bioavailability. This enables more effective study of its therapeutic potential in cancer research. -
Biochemical Assay Reagent
Cholesterol 5α,6α-epoxide is an epoxide derivative of cholesterol that serves as an important biochemical assay reagent. It is formed through the enzymatic oxidation of cholesterol in the liver and other tissues and plays a crucial role as an intermediate in bile acid biosynthesis, which is essential for the digestion and absorption of dietary fats. Additionally, this compound may influence cholesterol metabolism and transport, though its precise biological functions are still under investigation. -
Biochemical Assay Reagent
1,2-Distearoyl-sn-glycero-3-phosphate sodium is a phospholipid utilized primarily in biochemical assays and as a critical component in liposome formulations and drug delivery systems. This compound enhances the encapsulation of therapeutic agents, facilitating targeted delivery and improving drug solubility and bioavailability. Its unique chemical properties contribute to its effectiveness as a stabilizer and emulsifier in diverse research applications. -
Biochemical Assay Reagent
Cholesterol-PEG 600 is a biochemical assay reagent with applications in life science research. This compound acts as a versatile biological material, facilitating studies involving lipid biochemistry and membrane dynamics. Its unique structure enhances solubility and stability, making it ideal for applications such as drug formulation and the examination of cholesterol-related processes in cellular environments. -
Biochemical Assay Reagent
Dihexadecyl hydrogen phosphate is a phospholipid compound utilized as a biochemical assay reagent. It exhibits emulsifying properties, facilitating the mixing of immiscible substances such as oil and water, thereby enhancing texture and stability in various formulations. This compound finds applications in both the food industry, particularly in processed food production, and the pharmaceutical sector, where it assists in the formation of micelles, liposomes, and artificial membranes for drug delivery and research experiments. -
Biochemical Assay Reagent
Cholesterol decanoate is an ester formed from the reaction of cholesterol and capric acid, serving as a biochemical assay reagent. It exhibits bioactive properties that may have implications in addressing medical conditions such as hypercholesterolemia and inflammation-related disorders. Furthermore, this compound has potential applications in the food industry to enhance texture and stability in various formulations. -
Biochemical Assay Reagent
Dehydroergosterol is a naturally occurring fluorescent sterol analog that serves as a biochemical assay reagent, exhibiting excitation and emission wavelengths of 325 nm and 375 nm, respectively. This compound mimics cholesterol in cellular membranes, allowing for real-time imaging when conjugated with cholesterol-binding proteins. It is an effective tool for studying the sterol environment and elucidating intracellular sterol transport dynamics in live cells. -
Biochemical Assay Reagents
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC (PLPC) is a phospholipid that serves as a key component in lipid bilayer model systems. It is utilized in biochemical assays to investigate membrane properties and dynamics, notably in studies involving lipid oxidation. When combined with oxidized lipids such as 1-palmitoyl-2-(13-hydroxy-9,11-octadecanedienoyl)-lecithin (OHPLPC) and 1-palmitoyl-2-(13-hydroperoxy-9,11-octadecanedienoyl)-lecithin (HpPLPC), PLPC provides insight into the impacts of oxidative stress on membrane integrity and functionality. -
Biochemical Reagent
1-Thio-β-D-glucose sodium is a biochemical reagent that exhibits self-assembling properties to form hydrophilic monolayers with metal surfaces. This compound stabilizes lipid bilayers, enhancing membrane integrity, and offers protection to proteins against denaturation. Its unique characteristics make it valuable in studies involving biomolecular interactions and membrane biophysics. -
Biochemical Assay Reagent
1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine derivative that serves as a key biochemical assay reagent. Its surfactant properties facilitate the formation of micelles, liposomes, and various artificial membranes. This compound is essential for studies involving membrane dynamics, drug delivery systems, and lipid-based nanocarrier development. -
Biochemical Assay Reagent
Cholesterol nervonate is a biochemical assay reagent that serves as a key organic compound in life science research. It is utilized for its role in studying lipid metabolism and membrane dynamics. This compound is valuable for various biological assays aimed at understanding cellular functions and the physiological effects of cholesterol-associated pathways. -
Biochemical Assay Reagent
LNP Lipid-48 is an SM-102 analog designed as a biochemical assay reagent for the formation of lipid nanoparticles (LNPs). It exhibits effective encapsulation properties, facilitating the delivery of nucleotides and other therapeutic agents. This reagent is crucial for research applications involving drug delivery systems and gene therapy development, enabling the advancement of mRNA-based therapeutics and vaccines. -
Biochemical Assay Reagent
Cholesterol hexanoate is an ester formed from the reaction of cholesterol and caproic acid. This compound serves as a biochemical assay reagent and exhibits bioactive properties, making it a valuable tool in pharmacological research. Its potential applications include studying cholesterol metabolism and addressing inflammation-related diseases. Additionally, cholesterol hexanoate can be explored for enhancing food texture and stability, contributing to various research initiatives. -
Biochemical Assay Reagent
3-Methylthymidine is a biochemical assay reagent that serves as a substrate for fat mass and obesity-associated protein (FTO). This compound is utilized in studies investigating FTO activity, particularly in the context of obesity and metabolic disorders. Its application in research can help elucidate the mechanisms by which FTO influences cellular processes related to fat metabolism and development. -
UDP-GalNAc Analog
UDP-GalNAz disodium is an analogue of UDP-GalNAc disodium, serving as a donor substrate for N-acetylgalactosaminyltransferases, which facilitate the transfer of GalNAc to various saccharide or peptide acceptors. This compound features an azide group, making it a valuable reagent for click chemistry applications. UDP-GalNAz disodium can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. It is useful in the study of glycosylation pathways and the synthesis of complex glycoproteins. -
Drug Intermediate
Memantine lactose adduct is a key intermediate in the synthesis of adamantane amine antibiotics. This compound is derived from the reaction of Memantine with lactose, facilitating the development of novel therapeutic agents. Its role in the production of antibiotic compounds makes it valuable for biological research and pharmaceutical applications. -
Zopiclone Impurity
Deschloro-Zopiclone is an impurity of Zopiclone, the first non-benzodiazepine compound that enhances the activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the brain. This compound is relevant for studies focused on the pharmacological profiles and safety assessments of Zopiclone. It can be utilized in research related to sleep disorders and the analysis of medication impurities. -
Drug Intermediate
SOS1 Ligand Intermediate-7 is a critical chemical intermediate utilized in the synthesis of the SOS1 ligand, an important modulator of cellular signaling pathways. This compound plays a significant role in the production of PROTAC SOS1 degrader-1, facilitating targeted protein degradation research. Its applications extend to studies involving SOS1 activation and its implications in various biological processes. -
Impurity
Pregabalin diacid is characterized as an impurity of Pregabalin, a lipophilic analog of GABA (γ-aminobutyric acid) with notable anxiolytic and anticonvulsant properties. Its primary mechanism involves interaction with the α(2)β subunit of voltage-gated calcium channels, which are prevalent in both the peripheral and central nervous systems. Pregabalin is known to effectively induce hypoalgesia and enhance the management of behavioral disorders, making this impurity relevant in the context of quality control and pharmacological research. -
Cytochrome P450 Inhibitor
Verapamil EP Impurity C hydrochloride is a known impurity of Verapamil, primarily acting as a Cytochrome P450 inhibitor. This compound exhibits significant biological activity as a calcium channel blocker, contributing to its role as a first-generation P-glycoprotein (P-gp) inhibitor. Its utility in research includes studies on drug metabolism, pharmacokinetics, and interactions with P-gp transporters, making it a valuable reagent for pharmacological investigations. -
Biochemical Reagent
Ap3A is a vasoactive molecule primarily known for its role in regulating intracellular calcium (Ca2+) levels. It has been shown to promote the proliferation of vascular smooth muscle cells, making it a valuable reagent for research into cardiovascular biology and vascular growth mechanisms. Its applications extend to studies focusing on cellular signaling pathways and vascular pathologies. -
Biochemical Assay Reagent
Cholesterol n-Octanoate is an ester formed through the reaction of cholesterol and caprylic acid, serving as a valuable biochemical assay reagent. This compound exhibits bioactive properties that may influence various physiological processes, including cholesterol metabolism and inflammation. Its applications extend to pharmaceutical research aimed at addressing conditions related to elevated cholesterol levels and inflammatory diseases, as well as potential use in the food industry to enhance texture and stability. -
Biochemical Reagent
18:1-12:0 Biotin PC is a biochemical reagent primarily used for lipid blot analysis to investigate the interactions between Niemann-Pick C2 (NPC2) protein and lipids. Additionally, it serves as a key component in the preparation of liposomes, facilitating studies on lipid transport and cellular uptake mechanisms. This compound supports various applications in lipid research and membrane biology. -
Biochemical Assay Reagent
1,2-Dioctanoyl-sn-glycero-3-phosphocholine is a phospholipid that serves as a vital component in liposome formulations and drug delivery systems. This compound facilitates the formation of stable bilayers and vesicles, enhancing drug encapsulation and targeted delivery. Its properties as a stabilizer and emulsifier contribute to improved solubility and bioavailability of therapeutic agents, making it an essential reagent for biochemical assays and pharmaceutical research. -
Biochemical Assay Reagent
DOPE-PEG(2000) Amine ammonium is an amphiphilic copolymer characterized by a polyethylene glycol (PEG) chain of 2000 Da covalently linked to a phospholipid. This molecular structure allows for the formation of lipid bilayers or micelles in aqueous environments, facilitating the development of liposomes or nanoparticles for targeted drug delivery applications. Additionally, the reactive alkyne groups enable the formation of triazole linkages, which are beneficial for bioconjugation and further functionalization in biochemical assays. -
Biochemical Assay Reagent
LNP Lipid-12 is a critical component for the formulation of lipid nanoparticles (LNPs). This reagent facilitates the encapsulation and delivery of nucleic acids, enhancing their stability and efficacy in cellular applications. LNP Lipid-12 is particularly valuable in gene therapy, mRNA delivery, and other biochemical assays that require efficient and targeted transport systems. -
Biochemical Assay Reagent
LNP Lipid-182 is a key biochemical assay reagent utilized in the formulation of lipid nanoparticles (LNPs). This compound facilitates efficient encapsulation and delivery of nucleotides and other therapeutic agents. Its application is particularly significant in the fields of gene therapy and vaccine development, where precise lipid assembly is critical for enhancing cellular uptake and bioavailability. -
Biochemical Assay Reagent
LNP Lipid II-10 is a biochemical assay reagent designed for the formulation of lipid nanoparticles (LNPs). This compound facilitates the production of LNPs, which are essential for drug delivery applications, particularly in mRNA therapeutics. Its role in enhancing lipid bilayer stability and encapsulation efficiency makes it a crucial tool for researchers in the fields of nanomedicine and vaccine development. -
Biochemical Assay Reagent
Atorvastatin calcium hydrate is a potent HMG-CoA reductase inhibitor, primarily utilized as a biochemical assay reagent. This compound effectively lowers levels of low-density lipoprotein (LDL) cholesterol and triglycerides, contributing to a decreased risk of cardiovascular events such as heart attacks and strokes. Its distinct chemical properties and mechanism of action make it valuable for research applications focused on lipid metabolism and cardiovascular health. -
Impurity of Pantoprazole
N3-Methyl pantoprazole is an impurity of the proton pump inhibitor Pantoprazole. It serves as a significant reference standard for quality control and analytical research in pharmaceutical development. Its characterization aids in understanding the metabolic pathways and stability of Pantoprazole, providing insight into the safety and efficacy profiles of related compounds. This reagent is essential for researchers examining the pharmacological aspects of proton pump inhibitors. -
Biochemical Reagent
Galactose 1-phosphate uridylyltransferase (GALT) is a critical enzyme that catalyzes the conversion of galactose-1-phosphate into uridine diphosphate galactose, playing a pivotal role in the Leloir pathway of galactose metabolism. Deficiency of GALT is linked to classic galactosemia, making this enzyme significant for metabolic disease studies. Research involving GALT can enhance the understanding of galactose metabolism and its associated disorders. -
Biochemical Assay Reagent
Magnesium Ionophore III (ETH 4030) is a potent ionophore that modulates intracellular magnesium concentrations by enhancing the permeability of cell membranes to magnesium ions. This compound significantly influences cell functions and metabolic activities, making it a valuable tool for investigating the role of magnesium in various biological processes. Magnesium Ionophore III is widely utilized in research focused on cell physiology and the implications of magnesium in cellular signaling and metabolism. -
Biochemical Assay Reagent
Lead Ionophore IV is an ionophore that facilitates the transport of metal ions, particularly lead ions, across biological membranes. This reagent is utilized in biochemical assays to investigate the impact of lead on cellular functions and to explore its biological implications. Additionally, Lead Ionophore IV serves as a tool in the development of drug delivery systems aimed at enhancing the bioavailability of therapeutic compounds. -
Biochemical Assay Reagent
L-Lyxose is a five-carbon aldose sugar that serves as a vital biochemical assay reagent. It is primarily utilized in the study of carbohydrate metabolism and as a substrate in various enzymatic assays. Additionally, L-Lyxose plays a role in research related to glycosylation and cell signaling, aiding in the exploration of various biological processes. -
Exenatide Impurity
(Des-Gly2)-Exenatide is a structural variant of Exenatide, acting as an impurity in this peptide-based drug. Its presence is significant for quality control and purity assessment in pharmaceutical formulations. Researchers utilize this compound to study the stability and degradation pathways of Exenatide, enhancing analytical methods within peptide characterization and drug development processes. -
Biochemical Assay Reagent
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid primarily involved in stabilizing the lipid bilayer of cell membranes. Its role as a key component enhances membrane integrity and fluidity, making it a valuable reagent for various biochemical assays. This compound is essential for studying membrane dynamics, cellular signaling, and lipid-protein interactions in research applications. -
Biochemical Reagent
γ-Glutamyltransferase (GGT) from porcine kidney is an enzyme that plays a crucial role in the metabolism of glutathione. It achieves this by cleaving extracellular glutathione, thereby enhancing the availability of amino acids and maintaining cytoplasmic glutathione levels, which are vital for cellular defense against oxidative stress. GGT from porcine kidney is primarily utilized in biochemical research, particularly in studies related to pancreatic cancer. -
Biochemical Assay Reagent
Malondialdehyde tetrabutylammonium serves as a biochemical assay reagent and is recognized as a significant biomarker for oxidative stress. This compound can effectively indicate lipid peroxidation, providing crucial insights into cell damage and overall oxidative status. Its applications extend across food and cosmetic research, where it is utilized to monitor product stability and safety. Additionally, Malondialdehyde tetrabutylammonium may serve as a potential biomarker for a variety of diseases, aiding in the exploration of pathophysiological mechanisms. -
Biochemical Assay Reagent
3-Hydroxyoctanoic acid acts as an agonist for the orphan receptor GPR109B, promoting an increase in intracellular calcium levels in human neutrophils expressing this receptor. This hydroxylated fatty acid, which occurs in the lipopolysaccharides of Pseudomonas aeruginosa and in poly(3-hydroxyalkanoate) produced by Pseudomonas oleophores, plays a role in metabolic studies. Research indicates that 3-hydroxyoctanoic acid interferes with lipolysis in human adipocytes and demonstrates significant changes in plasma levels under various dietary conditions, making it a valuable reagent for biochemical assays focused on metabolic regulation and related disorders. -
Biochemical Reagent
(S)-2-Hydroxybutanoic acid is the S-enantiomer of 2-Hydroxybutanoic acid, a biochemical reagent with significant roles in metabolic studies. This compound serves as a biomarker for insulin resistance, providing insights into metabolic disorders and protein metabolism. Its application in research is crucial for understanding the pathways associated with insulin signaling and metabolic health. -
Biochemical Assay Reagent
Amylose is a polysaccharide that primarily functions as a biochemical assay reagent. It interacts with proteins and free fatty acids through non-covalent forces, such as hydrophobic and electrostatic interactions, facilitating the formation of ternary complexes. This characteristic is essential in the study of starch structure and digestion, making amylose pivotal in food science and carbohydrate metabolism research. Additionally, it plays a significant role in investigations focused on controlling glycemic responses by influencing the rate of starch digestion. -
Biochemical Assay Reagents
α-Lactose hydrate, a disaccharide composed of glucose and galactose, serves as a crucial biochemical assay reagent. It exists in two isomeric forms, α and β, and plays significant roles in the food and pharmaceutical industries. Its applications include acting as a bulking or agglomerating agent, as well as a diluent for various compounds such as pigments, flavors, and enzymes, facilitating diverse biochemical analyses and formulations. -
Drug Intermediate
5-Methoxyindole is an indole derivative that serves as a crucial intermediate in drug synthesis. It is primarily utilized to produce compounds such as 5-methoxytryptophan and N-acetyl 5-methoxytryptamine. This compound demonstrates significant anti-cancer and anti-inflammatory activities, making it relevant for research in oncology and inflammation-related studies. -
Biochemical Assay Reagent
3-Penten-2-one is a biochemical assay reagent that modulates nitric oxide production by inhibiting inducible nitric oxide synthase expression. This compound exerts its effects through the induction of heme oxygenase-1 in RAW264.7 macrophages activated by lipopolysaccharides (LPS). Its applications extend to studies involving inflammatory responses and the regulation of oxidative stress. -
Biochemical Assay Reagent
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC) is a phospholipid that exhibits dual fatty acid composition, featuring palmitic acid at the sn-1 position and arachidonic acid at the sn-2 position. PAPC plays a significant role in studies involving oxidative stress, as its oxidation products are implicated in chronic inflammation and vascular diseases. This reagent is widely utilized in biochemical assays to investigate the signaling pathways associated with oxidized phospholipids. Additionally, reduced levels of PAPC have been observed in isolated human multiple myeloma cells, highlighting its relevance in cancer research. -
Biochemical Assay Reagent
Dextrin is a low molecular weight carbohydrate resulting from starch hydrolysis. As a biochemical assay reagent, it serves as an effective thickener, stabilizer, and binder in food formulations, enhancing texture and shelf-life. In addition to its applications in food production, dextrin is integral to various industrial processes, including adhesives, paper, textiles, construction, and packaging, due to its unique chemical properties. -
Biochemical Reagent
6-Hydroxyindole is a biochemical reagent that serves as a long-lasting inhibitor of the organic anion transporting polypeptide 1B1 (OATP1B1). This compound is notably elevated in the plasma of patients with renal failure, providing insights into its role in drug metabolism and transport. Its applications in research include studies on pharmacokinetics, drug interactions, and the physiological effects related to renal impairment. -
Drug Intermediate
D-Threonine is an important unnatural amino acid primarily utilized as a chiral building block in pharmaceutical synthesis. As a metabolite of Saccharomyces cerevisiae, it plays a crucial role in various biochemical pathways. D-Threonine can be enzymatically cleaved by D-threonine aldolase to yield glycine and acetaldehyde, highlighting its potential in drug development and metabolic research applications. -
Biochemical Assay Reagent
L-Citrulline DL-malate is an organic compound that enhances the production of nitric oxide, thereby improving circulation and potentially increasing athletic performance. It is widely utilized in biochemical assays and is recognized for its ability to reduce muscle fatigue. Additionally, L-Citrulline DL-malate has applications in agriculture, where it contributes to enhancing plant immunity, making it a versatile reagent for various research fields.
