Peptides

DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT).

Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP), retains the full OGP-like activity. Osteogenic Growth Peptide (10-14) is responsible for the binding to the OGP receptor and activates an intracellular Gi-protein-MAP kinase signaling pathway. Osteogenic Growth Peptide (10-14) is a potent mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acts as a Src inhibitor.

Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human Ki values of 3.0 and 0.76 nM. Ac-YVAD-CHO is also a caspase-1 inhibitor. Ac-YVAD-CHO can suppress the production of mature IL-lβ.

Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs).

Lysipressin (Lysine vasopressin) acetate is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase.

Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al.

DAMGO TFA is a μ-opioid receptor (μ-OPR ) selective agonist with a Kd of 3.46 nM for native μ-OPR.

[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.

Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding.

RNAIII-inhibiting peptide(TFA) is a potent inhibitor of Staphylococcus aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.

Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) TFA gives depressor and bradycardic effects when applied to the nucleus tractus solitarius.

Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia.

Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors.

D-a-tert-Butyl-Gly-OH is a leucine derivative.

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates.

Fmoc-Ser(tBu)-OH is a serine derivative.

Fmoc-Asp(OAll)-OH is an aspartic acid derivative.

Fmoc-D-Ser(tBu)-OH is a serine derivative.

Fmoc-D-Nle-OH is a leucine derivative.

Fmoc-Phe(4-CN)-OH is a phenylalanine derivative.

Fmoc-L-Norleucine is a leucine derivative.

Fmoc-D-Pro-OH is a proline derivative.

Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation.

Fmoc-D-Gln(Trt)-OH is a glutamine derivative.

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-D-asparagine is an asparagine derivative.

Fmoc-Asp-OtBu is an aspartic acid derivative.

Fmoc-Cys(Acm)-OH is a cysteine derivative.

Boc-D-3-Pal-OH is an alanine derivative.

H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

H-Phg-OH is a Glycine derivative.

Fmoc-Ser(HPO3Bzl)-OH is a serine derivative.

4-Aminobutylphosphonic acid is aamino acids and their derivatives.

N2,N6-Bis(tert-butoxycarbonyl)-D-lysine is a lysine derivative.

Boc-Tyr-OtBu is a tyrosine derivative.

Fmoc-Cpg-OH is a Glycine derivative.

N6-Propionyl-L-lysine is a lysine derivative.

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine is a lysine derivative.

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ.

L-Phenylalanyl-L-leucine is a leucine derivative.

N-Isobutyrylglycine is a Glycine derivative.

cis-Fmoc-Pro(4-N3)-OH is a proline derivative. cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

VSV-G Peptide is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein.

Boc-Asp(OtBu)-OH is an aspartic acid derivative.

(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexylacetic acid is a Glycine derivative.

(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexylacetic acid is a Glycine derivative.

H-Phe(4-I)-OH is a phenylalanine derivative.

Fmoc-Ser-OH is a serine derivative.

Fmoc-Cys(Trt)-OH is a cysteine derivative.

Fmoc-β-Ala-OH is an alanine derivative.

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanoic acid is an alanine derivative.