Signaling Pathway
TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function.
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| Discription | TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function. |
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| Catalog Num | A22832 |
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| Formula | C107H150N34O32S2 |
| Molecular Weight | 2488.67 |
| CAS Number | 2426685-25-6 |
| Sequence shortening | SGQYASYHCWCWRDPGRSGGSK |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
