Catalog No.
Product Name
Application
Product Information
Citations
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Peptide Connecting The A And B Chains Of Proinsulin
Proinsulin C-peptide (human) is a 31-amino acid peptide that facilitates the proper folding of proinsulin by connecting its A and B chains. This peptide has been shown to inhibit high glucose-induced upregulation of PDGF-β receptor protein expression and the phosphorylation of p42/p44 MAP kinase. Additionally, Proinsulin C-peptide enhances the deformability of erythrocytes in type 1 diabetes and suppresses the proliferation of rat aortic smooth muscle cells under hyperglycemic conditions, with potential implications for vascular complications in diabetes research. -
Insulinotropic Polypeptide
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid-derived analog of glucose-dependent insulinotropic polypeptide that enhances antihyperglycemic and insulinotropic effects. This compound exhibits significant activity in promoting insulin secretion in response to glucose, making it a valuable tool for investigating diabetes, insulin resistance, and obesity. Its improved properties allow for detailed research into metabolic disorders and the mechanisms underlying glycemic control. -
Insulinotropic Polypeptide
Gastric Inhibitory Polypeptide (1-30), porcine is an insulinotropic polypeptide that enhances the secretion of insulin and somatostatin. This truncated form, missing the C-terminal 12 amino acids of the natural GIP, maintains key biological activity, making it valuable for research in glucose metabolism and endocrine function. It is particularly useful in studies examining the role of incretin hormones in insulin regulation. -
Insulinotropic Polypeptide
GIP (1-30) amide, porcine is an agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor, exhibiting high affinity comparable to native GIP (1-42). This peptide demonstrates significant insulin-stimulating activity while also serving as a weak inhibitor of gastric acid secretion. It is valuable in research focused on metabolic disorders, insulin signaling, and gastrointestinal physiology. -
Peptide
[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) is a phosphorylated peptide that targets the insulin receptor, serving as a substrate for insulin receptor tyrosine kinase activity. This reagent is essential for studying insulin signaling pathways and receptor activation. It provides valuable insights into the mechanisms of metabolism, growth, and differentiation mediated by insulin action in various biological systems. -
Insulinogen Fraction
C-Peptide 2 (rat) is a 31-amino-acid peptide derived from proinsulin that plays a crucial role in insulin processing. This compound is known for its ability to inhibit glucose-induced insulin secretion, making it valuable for studies related to insulin regulation and diabetes research. C-Peptide 2 (rat) can serve as a useful tool in the investigation of insulin dynamics and metabolic disorders. -
Gastric Inhibitory Polypeptide
[Tyr0] Gastric Inhibitory Peptide (23-42), human is a variant of the glucose-dependent insulinotropic polypeptide (GIP) that primarily targets the regulation of gastric acid secretion. It acts as a weak inhibitor of gastric acid release while promoting insulin secretion in a glucose-dependent manner. This peptide is useful in research focused on diabetes and obesity, helping to elucidate the mechanisms of metabolic regulation and potential therapeutic interventions. -
Bioactive Peptide
IRS-1 Peptide, FAM labeled, is a bioactive peptide that acts as a crucial signaling mediator in insulin signaling pathways. This peptide facilitates the study of insulin receptor substrate interactions and downstream signaling events, making it an essential tool for research in diabetes, obesity, and metabolic disorders. The FAM labeling allows for convenient detection and analysis in various biochemical assays, enhancing visualization and quantification in cellular studies. -
Insulin-Releasing Peptide
CPF-7, a precursor fragment of caerulein, functions as an insulin-releasing peptide by stimulating insulin secretion. Additionally, it promotes epithelial-mesenchymal transition through the upregulation of Snai1 expression in PANC-1 ductal cells and induces exocrine plasticity by enhancing Ngn3 expression. This peptide is valuable for research applications focused on the mechanisms of type 2 diabetes and pancreatic cell plasticity. -
Antitumour Peptide
Tigapotide is an antitumor peptide that primarily targets cancer cell apoptosis and tumor-associated signaling pathways. It effectively reduces the development of skeletal metastases in prostate cancer by lowering levels of parathyroid hormone-related peptide (PTHrP). This compound is valuable for research applications focused on understanding metastatic processes and developing targeted therapies for prostate cancer. -
Antitumor Peptide
Tumor Targeted Pro-Apoptotic Peptide (CNGRC-GG-D(KLAKLAK)2) is designed to selectively induce apoptosis in cancer cells through the disruption of mitochondrial membranes. Its pro-apoptotic properties exhibit significant anticancer activity in preclinical models, providing a promising avenue for cancer research and therapeutic development. This peptide serves as a valuable tool for investigating targeted apoptosis mechanisms in tumor biology. -
Antiangiogenic TSP Peptide
ABT-510 is an anti-angiogenic thrombospondin-1 (TSP) peptide analogue that promotes apoptosis and suppresses tumor growth in epithelial ovarian cancer utilizing an orthotopic, syngeneic model. Additionally, ABT-510 demonstrates the ability to diminish angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease (IBD). This reagent serves as a valuable tool for research focused on cancer therapies, particularly regarding ovarian cancer, as well as studies related to inflammatory bowel disease. -
Peptide Ligand
SP94 is a peptide ligand that exhibits high specificity for hepatocellular carcinoma cells. It selectively binds to various hepatocellular carcinoma cell lines in vitro, demonstrating significant inhibition of tumor growth in mouse models by promoting apoptosis and reducing angiogenesis. SP94 serves as a valuable tool for imaging and studying hepatocellular carcinoma, facilitating research into targeted therapies and diagnostic applications. -
Pro-Apoptotic Peptide
CIGB-300 is a pro-apoptotic peptide that targets casein kinase 2 (CK2). It exhibits potent anticancer activity by disrupting CK2 phosphorylation, leading to apoptosis in various tumor cell lines. This compound is valuable for cancer research, particularly in studies focused on apoptosis and CK2 modulation. -
Bioactive Peptide
Abl protein tyrosine kinase substrate is a bioactive peptide designed to interact specifically with Abl kinase, a crucial component of the gag-Abl fusion protein derived from the Abelson murine leukemia virus. This substrate facilitates the study of Abl kinase activity through various biochemical assays, including Western blotting and kinase assays. Its precise reactivity enables researchers to investigate kinase signaling pathways and their roles in cellular processes, particularly in cancer research. -
regenerative peptide
Rusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. - D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain.
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non-peptide CCR1 antagonist
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. -
non-peptide nociceptin receptor (NOP) agonist
MT-7716 free base (W-212393) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention. -
integrin-ligand interactions inhibitor
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. - Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect.
- Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer.
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VPAC2 agonist
Bay 55-9837 is a potent and highly selective agonist of VPAC2, with a Kd of 0.65 nM. Bay 55-9837 may be a useful therapy for the research of type 2 diabetes. - Cyclo(L-Phe-L-Val) is a potent inhibitor of enzymes isocitrate lyase (ICL) (IC50=27 μg/mL). cyclo(L-Phe-L-Val) inhibits the gene transcription of ICL in C. albicans under C2-carbon-utilizing conditions.
- Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection.
- MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction.
- (R)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid is a Glycinederivative.
- (S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid is a Glycine derivative.
- N-tert-Butoxycarbonyl-D-tyrosine methyl ester is a tyrosine derivative.
- Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis.
- Benzyl ethyl-L-valinate hydrochloride is a valine derivative.
- Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir to avoid the production of sofibuvir degradation impurities.
- Tos-Gly-Pro-Arg-ANBA-IPA (tos-GPR-ANBA-IPA) acetate is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA acetate can be used for luminescence measurement.
- Palmitoyl tripeptide-1 hydrochloride is a fatty acid modified polypeptide. Palmitoyl Tripeptide-1 has good wrinkle-removing effect.
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GnRH Receptor agonist
Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis. - (Arg)9 (Nona-L-arginine) TFA is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 TFA has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.
- Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 acetate has antinociceptive properties.
