Ruxolitinib Phosphate

Catalog No.: A11552

JAK inhibitor

Ruxolitinib Phosphate

Ruxolitinib Phosphate Chemical Structure

CAS NO. 1092939-17-7

Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$70.00
50 mg
$125.00
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Biological Activity

Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities.
In vitro DMSO 73 mg/mL (180.53 mM)
Water 26 mg/mL (64.29 mM)
Ethanol 7 mg/mL (17.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.73 mL 123.65 mL 247.3 mL
0.5 mM 4.95 mL 24.73 mL 49.46 mL
1 mM 2.47 mL 12.36 mL 24.73 mL
5 mM 0.49 mL 2.47 mL 4.95 mL

*The above data is based on the productmolecular weight 404.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11552
Actions Inhibitor
CAS No. 1092939-17-7
Formula C17H21N6O4P
M. Wt 404.37
Solubility DMSO
Purity >98%
Synonyms INCB018424, INCB 018424, INCB-018424
SMILES N#CC[[email protected]@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4.O=P(O)(O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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