Ruxolitinib Phosphate

Catalog No.: A11552
JAK inhibitor
Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities.
Grouped product items
Product Name Price Stock Qty
Ruxolitinib Phosphate 5mg
$50.00
In stock
Ruxolitinib Phosphate 10mg
$70.00
In stock
Ruxolitinib Phosphate 50mg
$125.00
In stock
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Biological Activity
Discription Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities.
Targets
Target Value
Product Information
Catalog Num A11552
Formula C17H21N6O4P
Molecular Weight 404.37
CAS Number 1092939-17-7
SMILES N#CC[C@@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4.O=P(O)(O)O
Synonyms INCB018424, INCB 018424, INCB-018424
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 73 mg/mL (180.53 mM)
Water 26 mg/mL (64.29 mM)
Ethanol 7 mg/mL (17.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.73 mL 123.65 mL 247.3 mL
0.5 mM 4.95 mL 24.73 mL 49.46 mL
1 mM 2.47 mL 12.36 mL 24.73 mL
5 mM 0.49 mL 2.47 mL 4.95 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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