SC-58272 is a potent and selective inhibitor of N-myristoyltransferase (Nmt) in Candida albicans, exhibiting an IC50 of 56 nM against the strain B311. This compound demonstrates a 250-fold selectivity for the fungal enzyme when compared to the human counterpart. SC-58272 is valuable for research applications involving fungal pathogenesis and the study of myristoylation processes in C. albicans.
SC-58272 is a potent and selective inhibitor of N-myristoyltransferase (Nmt) in Candida albicans, exhibiting an IC50 of 56 nM against the strain B311. This compound demonstrates a 250-fold selectivity for the fungal enzyme when compared to the human counterpart. SC-58272 is valuable for research applications involving fungal pathogenesis and the study of myristoylation processes in C. albicans.
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