Verteporfin

Catalog No.: A12658

YAP inhibitor

Verteporfin Chemical Structure

CAS NO. 129497-78-5

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$120.00
25 mg
$240.00
50 mg
$400.00
10mM * 1mL in DMSO
$120.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.
Targets
VDA (Endothelial cells)
In vitro DMSO 100 mg/mL (139.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.91 mL 69.56 mL 139.12 mL
0.5 mM 2.78 mL 13.91 mL 27.82 mL
1 mM 1.39 mL 6.96 mL 13.91 mL
5 mM 0.28 mL 1.39 mL 2.78 mL

*The above data is based on the productmolecular weight 718.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12658
Actions Inhibitor
M. Wt 718.79
Formula C41H42N4O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 129497-78-5
Synonyms Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A.
SMILES O=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[[email protected]]6(C)[[email protected]](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5

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