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YAP inhibitor

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Catalog No. A12658

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Verteporfin 5mg A12658-5

Regular Price: $80.00

Special Price: $72.00

Verteporfin 10mg A12658-10

Regular Price: $120.00

Special Price: $108.00

Verteporfin 25mg A12658-25

Regular Price: $240.00

Special Price: $216.00

Verteporfin 50mg A12658-50

Regular Price: $400.00

Special Price: $360.00

Verteporfin 10mM * 1mL in DMSO A12658-10mM-D

Regular Price: $120.00

Special Price: $108.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.


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Publications citing Adooq Products
Verteporfin Citations (1)
  • Abe T, .et al. Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes, Toxicol Sci, 2018, Oct 1;165(2):408-419 PMID: 29893953

Chemical Information

Catalog Num A12658
Actions Inhibitor
M. Wt 718.79
Formula C41H42N4O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 129497-78-5
Synonyms Visudyne, BPD-MA, BpdMA, Benzoporphyrin D, Benzoporphyrin derivative monoacid ring A, Verteporfin, Visudyne
SMILES O=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[[email protected]]6(C)[[email protected]](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5

Biological Activity

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.
VDA (Endothelial cells)


Solubility (25°C)* In vitro DMSO 100 mg/mL (139.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.91 mL 69.56 mL 139.12mL
0.5 mM 2.78 mL 13.91 mL 27.82 mL
1 mM 1.39 mL 6.96 mL 13.91 mL
5 mM 0.28 mL 1.39 mL 2.78 mL

*The above data is based on the productmolecular weight 718.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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