Verubecestat (MK-8931)

Catalog No.: A16113
β-secretase/BACE1 inhibitor
Verubecesta is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.
Grouped product items
Product Name Price Stock Qty
Verubecestat 5mg
Special Price $56.00 Regular Price $70.00
In stock
Verubecestat 10mg
Special Price $88.00 Regular Price $110.00
In stock
Verubecestat 50mg
Special Price $320.00 Regular Price $400.00
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Verubecesta is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.
Product Information
Catalog Num A16113
Formula C17H17F2N5O3S
Molecular Weight 409.41
CAS Number 1286770-55-5
SMILES O=C(C1=NC=C(F)C=C1)NC2=CC=C(F)C([C@@](C3)(C)N=C(N)N(C)S3(=O)=O)=C2
Synonyms MK-8931, MK 8931, MK8931
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 77 mg/mL (188.07 mM)
Water Insoluble
Ethanol 39 mg/mL (95.26 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.43 mL 122.13 mL 244.25 mL
0.5 mM 4.89 mL 24.43 mL 48.85 mL
1 mM 2.44 mL 12.21 mL 24.43 mL
5 mM 0.49 mL 2.44 mL 4.89 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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