Y-27632

Name: Y-27632
Brand: Adooq Bioscience
SKU: A21448
Rating: 5 (3 reviews)

Catalog No.: A21448

ROCK-I/ROCK-II inhibitor

Adooq's Y-27632 has been cited by 3 publications

Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.

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Y-27632 146986-50-7 ROCK-I/ROCK-II inhibitor

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Grouped product items
Size	Price	Stock
1mg	$25.00	In stock
5mg	$30.00	In stock
10mg	$50.00	In stock
25mg	$90.00	In stock
50mg	$165.00	In stock
100mg	$280.00	In stock
200mg	$440.00	In stock
500mg	$730.00	In stock
*10mM 1mL in DMSO**	$35.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

Other Forms of Y-27632

Y-27632 2HCl

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Adooq Products cited in reputable paper

Adooq's Y-27632 has been cited by 3 publications

Ryan Lingerak, .et al. , British Journal of Cancer Research, 2025, 8(1): 756-774
Sara B Linker, .et al. , Curr Biol, 2022, Nov 21;32(22):4797-4807 PMID: 36228612
Renata Santos, .et al. , STAR Protoc, 2022, Mar 17;3(2):101261 PMID: 35313707

Biological Activity

Description

Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A21448
Formula	C14H21N3O
Molecular Weight	247.34
CAS Number	146986-50-7
SMILES	O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
Synonyms	Y27632, Y 27632
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂