Y-27632 2HCl

Catalog No.: A11001

ROCK Inhibitor

Y-27632 2HCl Chemical Structure

CAS NO. 146986-50-7, 129830-38-2

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$65.00
25 mg
$100.00
50 mg
$190.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).
Targets
ROCK1 (p160ROCK) (Cell-free assay) ROCK2 (Cell-free assay)
140 nM(Ki)300 nM(Ki)
In vitro (25°C) DMSO 64 mg/mL warmed (199.83 mM)
Water 14 mg/mL (43.71 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.22 mL 156.1 mL 312.21 mL
0.5 mM 6.24 mL 31.22 mL 62.44 mL
1 mM 3.12 mL 15.61 mL 31.22 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11001
Actions Inhibitor
M. Wt 320.3
Formula C14H21N3O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 146986-50-7, 129830-38-2
Synonyms N/A
SMILES C[[email protected]](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

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