Y-27632 2HCl

Name: Y-27632 2HCl
SKU: A11001
Price: 30 USD
Rating: 5 (41 reviews)

Catalog No.: A11001

ROCK Inhibitor

Adooq's Y-27632 2HCl has been cited by 41 publications

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
Product Name	Price	Stock
Y-27632 5mg	Special Price $30.00 Regular Price $45.00	In stock
Y-27632 10mg	Special Price $50.00 Regular Price $65.00	In stock
Y-27632 25mg	Special Price $80.00 Regular Price $100.00	In stock
Y-27632 50mg	Special Price $140.00 Regular Price $190.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Other Forms of Y-27632 2HCl

Y-27632

Contact your local distributors

Not your Region? View all Distributors

Adooq Products cited in reputable paper

Adooq's Y-27632 2HCl has been cited by 41 publications

Kyunghyun Park, .et al. , Advanced Therapeutics, 2024, 7(6)

Maude Hamilton, .et al. , Biol Open, 2024, Jan 15; 13(1): bio059919 PMID: 38252116

Oliver Podmanicky, .et al. , Hum Mol Genet, 2024, Mar 1; 33(5): 435-447 PMID: 37975900

Johannes Robert Fleischer, .et al. , Mol Cancer, 2023, Jan 24;22(1):17 PMID: 36691028

Vignesh Jayarajan, .et al. , Cells, 2023, Jan 17;12(3):346 PMID: 36766688

Giulia Bastianello, .et al. , Cell Rep, 2023, Dec 26;42(12):113555 PMID: 38088930

Charlotte Phelps, .et al. , Sci Rep, 2023, Oct 23;13(1):18062 PMID: 37872186

Mathilde Meyenberg, .et al. , Sci Rep, 2023, Aug 26;13(1):13964 PMID: 37633982

Yu-Ting Wu, .et al. , J Biomed Sci, 2023, Aug 21;30(1):70 PMID: 37605213

Heming Ning, .et al. , In Vitro Cell Dev Biol Anim, 2023, Jun;59(6):410-419 PMID: 37405627

Eric Lian, .et al. , STAR Protoc, 2023, May 22;4(2):102314 PMID: 37220001

Stephanie T Pohl, .et al. , Methods Mol Biol, 2023, 2584:371-387 PMID: 36495461

Charlotte Phelps, .et al. , Am J Physiol Cell Physiol, 2023, Mar 1;324(3):C787-C797 PMID: 36689673

Shunsuke Murakami, .et al. , Regen Ther, 2022, Nov 25;21:574-583 PMID: 36475025

Sergio Pedraza-Arevalo, .et al. , STAR Protoc, 2022, Aug 30;3(3):101656 PMID: 36092820

Ji-Hyun Lee, .et al. , Cell Stem Cell, 2022, May 5; 29(5): 826-839 PMID: 35523142

Adam Pietrobon, .et al. , Cell Rep, 2022, Jul 5;40(1):111048 PMID: 35793620

Sarkawt Hamad, .et al. , Stem Cell Res Ther, 2022, Jun 11;13(1):251 PMID: 35690874

Stasia Krishtul, .et al. , Polym Adv Technol, 2022, 33( 11): 3842-3852

Peter T Ruane, .et al. , Hum Reprod, 2022, Apr 1;37(4):777-792 PMID: 35079788

Takayuki Miyoshi, .et al. , J Gastroenterol, 2022, Jun;57(6):441-452 PMID: 35294680

Ana-Maria Cujba, .et al. , Cell Rep, 2022, Mar 1;38(9):110425 PMID: 35235779

Dan Zhao, .et al. , Poult Sci, 2022, Mar; 101(3): 101642 PMID: 35016046

Antigoni Gogolou, .et al. , Curr Protoc, 2021, Jun;1(6):e137 PMID: 34102038

Tiago De Oliveira, .et al. , Cancers (Basel), 2021, Mar 2;S2451-9456(21)00095-7 PMID: 33671096

Denise Muller, .et al. , BMC Med, 2021, Nov 16;19(1):300 PMID: 34781947

Ayumi Horikawa, .et al. , PloS one, 2021, Jul 12;16(7):e0254373 PMID: 34252142

Hayato Mizuta, .et al. , Nat Commun, 2021, Feb 24;12(1):1261 PMID: 33627640

Scott Bell, .et al. , Stem Cell Reports, 2021, Jul 13;16(7):1749-1762 PMID: 34214487

Shenyang Li, .et al. , J Cell Mol Med, 2020, Dec 20;25(2):1207-1220 PMID: 33342057

Takao FUCHIGAMI, .et al. , J Appl Oral Sci, 2020, 28: e20190558 PMID: 32348439

Jing-Yu Lin, .et al. , Cell Discov, 2020, 6: 20 PMID: 32284878

Yu Huang, .et al. , Stem Cells Int, 2019, 2019: 3975689 PMID: 31565060

XinYan, .et al. , Stem Cell Res, 2019, May 17 PMID: 31141763

Daniela F. Duarte Campos, .et al. , J Biomed Mater Res A, 2019, April 22 PMID: 31012205

Scott Bell, .et al. , Am J Hum Genet, 2019, May 2;104(5):815-834 PMID: 31031012

Ooi J, .et al. , Cell Rep, 2019, Feb 26;26(9):2494-2508 PMID: 30811996

Scott Bell, .et al. , Stem Cell Reports, 2018, Jul 10; 11(1):183-196 PMID: 29937144

Christina Zarouchlioti, .et al. , Am J Hum Genet, 2018, Apr 5; 102(4): 528-539 PMID: 29526280

Ai Takemoto, .et al. , Sci Rep, 2017, 7: 42186 PMID: 28176852

Scott Bell, .et al. , Stem Cells Transl Med, 2017, Mar; 6(3): 886-896 PMID: 28170165

Biological Activity

Discription

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).

Targets

Target	Value

Product Information

Catalog Num	A11001
Formula	C14H21N3O.2HCl
Molecular Weight	320.3
CAS Number	146986-50-7, 129830-38-2
SMILES	C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	Warmed: 61 mg/mL (190.46 mM)
	Water	13 mg/mL (40.59 mM)
	Ethanol	Insoluble
In vivo	saline	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.22 mL	156.1 mL	312.21 mL
0.5 mM	6.24 mL	31.22 mL	62.44 mL
1 mM	3.12 mL	15.61 mL	31.22 mL
5 mM	0.62 mL	3.12 mL	6.24 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Bioquote Limited.	The Raylor Centre,James Street, York YO10 3DW, United Kingdom Tel: 00 44 1904 431402 Fax: 00 44 1904 431409 www.bioquote.com [email protected]
Generon UK.	11 Whittle Parkway, Progress Business Park, Slough SL1 6DQ, United Kingdom Tel: +44 (0)1753 866 511 Fax: +44 (0)1753 208 899 www.generon.co.uk [email protected]