GABA Receptors



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Catalog No. Product Name Application Product Information
A15277

Vigabatrin

GABA-transaminase inhibitor
Vigabatrin is a structural analog of the inhibitory neurotransmitter ??-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.
A15441

Vigabatrin

GABA-T inhibitor
Vigabatrin is an antiepileptic drug that inhibits the breakdown of gamma-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T).
A15939

CTP354

GABA(A) modulator
CTP354 a novel deuterated subtype-selective GABA(A) modulator.
A14934

4-Aminobutyric acid

-
4-Aminobutyric acid is the chief inhibitory neurotransmitter in the mammalian central nervous system.
A13459

Muscimol hydrobromide

GABA(A) receptor agonist
Muscimol hydrobromide is a potent but toxic structural analog of g-aminobutyric acid (GABA), with a zwitterionic structure.
A14005

Muscimol

GABAA/GABAC agonist
Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity sites (Kd = 10 and 270 nM, respectively), stimulating chloride efflux with an EC50 value of 200 nM.
A13613

Guvacine hydrochloride

GABA uptake inhibitor
Guvacine hydrochloride inhibits GABA uptake (IC50 values are 14, 58, 119 and 1870 uM for hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1 respectively).
A13769 SALE

Indiplon

GABAA receptor modulator
Indiplon is a pyrazolopyrimidine that acts as a high-affinity positive allosteric modulator of the GABAA receptor, potentiating GABA-activated chloride currents in a dose-dependent and reversible manner.
A14349

RO 15-3890

benzodiazepine receptor antagonist
Ro 15-1788 is a benzodiazepine receptor antagonist.
A15083

Etifoxine

Anxiolytic anticonvulsant
Etifoxine is potentiator of GABAA receptor function in cultured neurons.
A15084

Etifoxine hydrochloride

Anxiolytic anticonvulsant
Etifoxine hydrochloride is potentiator of GABAA receptor function in cultured neurons.
A15288 SALE

Zolpidem

Benzodiazepine agonist
Zolpidem is an inhibitory neurotransmitter, by binding to GABAA receptors at the same location as benzodiazepines.
A13198

Tiagabine

GABA reuptake inhibitor
Tiagabine is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor.
A14004

Picrotoxin

GABAA receptor antagonist
Picrotoxin is a GABAA receptor antagonist. This compound has been shown to increase noradrenaline levels and turnover in the hypothalamus.
A16135

Tiagabine hydrochloride

GABA reuptake inhibitor
Tiagabine is an anti-convulsive medication. The medication is also utilized in the treatment of panic disorder, as are a few other anticonvulsants.
A16171

Piperazine

GABA receptor agonist
Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring.
A13449 SALE

Lorediplon

GABAA receptor modulator
Lorediplon is a novel non-benzodiazepine, hypnotic drug acting as a GABAA receptor modulator,
A16336

U-93631

GABAA receptor ligand
U-93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.
A14343 SALE

a5IA

Benzodiazepine agonist
a5IA is a nootropic drug invented in 2004 by a team working for Merck, Sharp and Dohme, which acts as a subtype-selective inverse agonist at the benzodiazepine binding site on the GABAA receptor.
A13932

Cloflubicyne

GABA antagonist
Cloflubicyne is a potent non-competitive GABA antagonist, convulsant, laboratory insecticide.
A10252

Dihydromyricetin (Ampeloptin)

Dihydropyrimidinase Inhibitor
Dihydromyricetin (Ampelopsin (flavanol); Ampeloptin) is a natural antioxidant with good prospects.
A10121 SALE

Baicalin

HIV-1 production Inhibitor
Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors.
A10631 SALE

Nefiracetam (Translon)

-
Nefiracetam is cognitive enhancer. It activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems.
A10849

SKF 89976A HCl

GABA uptake inhibitor
SKF 89976A hydrochloride is a potent inhibitor of GABA uptake with IC50 of 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
A10397 SALE

Flumazenil

Benzodiazepine antagonist
Flumazenil, an imidazobenzodiazepine derivative, antagonizes the actions of benzodiazepines on the central nervous system. Flumazenil competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex. Flumazenil is a weak partial agonist in some animal models of activity, but has little or no agonist activity in humans.
A10412 SALE

Furosemide

-
Furosemide is a non-competitive antagonist at GABAA receptors with ~ 100-fold greater selectivity for α6-containing receptors than α1-containing receptors.
A10413 SALE

Gabapentin

-
Gabapentin (Neurontin) is a pharmaceutical agent, specifically a GABA analogue.
A10414

Gabapentin Hydrochloride

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Gabapentin Hydrochloride is a GABA analogue.
A10754

Primidone (Mysoline)

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Primidone is an anticonvulsant. Potentiates GABAA receptor function.
A12590

(+)-Bicuculline

GABAA antagonist
(+)-Bicuculline is a classical GABAA antagonist.
A12993

Zaleplon

-
Zaleplon is a non-benzodiazepine agent that acts as an agonist at the benzodiazepine site.
A13726

AWD 131-138

GABAA receptor agonist
AWD 131-138 is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models.
A13696

2-Hydroxysaclofen

GABAB receptors antagonist
2-Hydroxysaclofen is a potent and selective antagonist at GABAB receptors.
A13784

Bretazenil

GABAA agonist
Bretazenil, a benzodiazepine receptor partial agonist, as an adjunct in the prophylactic treatment of OP poisoning.
A14281

Oxiracetam

-
Oxiracetam is a cyclic derivative of gamma-aminobutyric acid (GABA).
A12298

Bemegride

-
Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.

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