Primidone-d5 is a deuterium-labeled analog of Primidone, primarily known for its inhibitory action on the transient receptor potential melastatin 3 (TRPM3) channel, with an IC50 value of 0.6 μM. This reagent also inhibits receptor-interacting protein (RIP) kinase and voltage-gated sodium channels, while acting as an antagonist at the GABA receptor. Primidone-d5 is valuable for research in pain management and seizure disorders, enabling studies focused on its analgesic and anticonvulsant properties.
Primidone-d5 is a deuterium-labeled analog of Primidone, primarily known for its inhibitory action on the transient receptor potential melastatin 3 (TRPM3) channel, with an IC50 value of 0.6 μM. This reagent also inhibits receptor-interacting protein (RIP) kinase and voltage-gated sodium channels, while acting as an antagonist at the GABA receptor. Primidone-d5 is valuable for research in pain management and seizure disorders, enabling studies focused on its analgesic and anticonvulsant properties.
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