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Publications citing Adooq Products
Chemical Information
| Catalog Num | A10397 |
|---|---|
| Actions | Antagonist |
| M. Wt | 303.3 |
| Formula | C15H14FN3O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 78755-81-4 |
| Synonyms | Ro 15-1788 |
| SMILES | CCOC(=O)c1ncn2c1CN(C)C(=O)c1c2ccc(c1)F |
| Chemical Name | 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, ethyl ester |
Description |
Flumazenil, an imidazobenzodiazepine derivative, antagonizes the actions of benzodiazepines on the central nervous system. Flumazenil competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex. Flumazenil is a weak partial agonist in some animal models of activity, but has little or no agonist activity in humans. | ||||||||||
Targets |
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| Solubility (25°C)* | In vitro | DMSO | 5 mg/mL (16.48 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.97 mL | 164.85 mL | 329.71mL |
| 0.5 mM | 6.59 mL | 32.97 mL | 65.94 mL |
| 1 mM | 3.3 mL | 16.49 mL | 32.97 mL |
| 5 mM | 0.66 mL | 3.3 mL | 6.59 mL |
*The above data is based on the productmolecular weight 303.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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