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|Storage||at -20°C 3 years Powder|
|Chemical Name||8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, ethyl ester|
|Flumazenil, an imidazobenzodiazepine derivative, antagonizes the actions of benzodiazepines on the central nervous system. Flumazenil competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex. Flumazenil is a weak partial agonist in some animal models of activity, but has little or no agonist activity in humans.|
|Solubility (25°C)*||In vitro||DMSO||5 mg/mL (16.48 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||32.97 mL||164.85 mL||329.71mL|
|0.5 mM||6.59 mL||32.97 mL||65.94 mL|
|1 mM||3.3 mL||16.49 mL||32.97 mL|
|5 mM||0.66 mL||3.3 mL||6.59 mL|
*The above data is based on the productmolecular weight 303.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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