BX471 hydrochloride

Catalog No.: A21886

non-peptide CCR1 antagonist

BX471 hydrochloride

BX471 hydrochloride Chemical Structure

CAS NO. 288262-96-4

BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

Availability: In stock

Package Price Qty
10 mg
$135.00
25 mg
$270.00
50 mg
$465.00
100 mg
$795.00
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Biological Activity

BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.22 mL 106.08 mL 212.16 mL
0.5 mM 4.24 mL 21.22 mL 42.43 mL
1 mM 2.12 mL 10.61 mL 21.22 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21886
Actions Antagonist
M. Wt 471.35
Formula C21H25Cl2FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 288262-96-4
Synonyms ZK-811752 hydrochloride,ZK811752, ZK 811752,TAK 659, TAK659
SMILES O=C(N)NC1=CC(Cl)=CC=C1OCC(N2[[email protected]](C)CN(CC3=CC=C(F)C=C3)CC2)=O.[H]Cl

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