Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
5-(Aminomethyl)-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized in studies focusing on therapeutic strategies and molecular mechanisms underlying tumorigenesis. -
Purine Nucleoside Analog
2′,3′-Dideoxy-3′-fluoro-5-methylcytidine is a purine nucleoside analog that exerts significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized in studies focused on the modulation of nucleoside metabolism and the exploration of therapeutic strategies for lymphoid tumors. -
Purine Nucleoside Analog
N2,N2-Dimethylamino-6-deamino adenosine is a purine nucleoside analog known for its potential anticancer properties. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms involving the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research and therapeutic development, contributing to the understanding of nucleoside metabolism in malignancies. -
Nucleoside Metabolite
Aminoacetaldehyde is a nucleoside metabolite that plays a critical role in various biochemical pathways. It is involved in the metabolism of amino acids and nucleotides, facilitating cellular processes such as energy production and biosynthesis. This compound is valuable for research applications focusing on metabolic regulation and nucleotide synthesis. -
Purine Nucleoside Analog
DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog that serves as a key reagent in nucleic acid synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Its applications extend to cancer research, where it is utilized to explore therapeutic pathways and mechanisms in tumorigenesis. -
Purine Nucleoside Analog
5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine is a purine nucleoside analog that exhibits potent antitumor activity. This compound is primarily utilized in the study of indolent lymphoid malignancies. Its biological mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. -
Guanosine Analog
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog that targets Toll-like receptor 7 (TLR7) to exert its biological effects. It demonstrates immunostimulatory activity, eliciting type I interferon responses that confer antiviral properties in various animal models. This compound is valuable for researching the modulation of immune responses and the development of antiviral therapeutics. -
Adenosine Analog
N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenosine analog with the potential to act as a smooth muscle vasodilator and inhibit cancer progression. This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc). It serves as a valuable tool in chemical research, particularly for applications involving bioconjugation and the development of novel therapeutics. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a purine nucleoside analog that exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on evaluating the effects of purine metabolism in oncology and therapeutics. -
Purine Nucleoside Analog
2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is employed in various studies aimed at understanding the therapeutic potential of nucleoside analogs in oncological applications. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog with significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its ability to interfere with cellular proliferation highlights its potential in cancer research and therapeutic applications. -
Purine Nucleoside Analog
Rev dC(Bz)-5'-amidite is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, and can induce apoptosis in cancer cells. This compound is valuable for research applications focusing on cancer therapeutics and the study of nucleoside metabolism. -
Purine Nucleoside Analog
N-Benzoyl-3′-O-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic development. This compound is utilized in studies aimed at understanding the effects of purine analogs on cellular processes and their potential in oncology. -
Thymidine Analog
5-Benzylaminocarbonyl-2’-O-methyluridine is a thymidine analog that primarily targets the incorporation of nucleotides into DNA. This compound exhibits insertional activity towards replicated DNA, making it a valuable tool for studying DNA synthesis and cell labeling. It is widely used in research applications involving nucleic acid metabolism and monitoring cellular processes. -
5-Hydroxyisourate Product
2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline functions primarily as a substrate in the hydrolysis of 5-hydroxyisourate. This compound is involved in biochemical pathways leading to the production of (S)-allantoin through stereoselective decarboxylation, mediated by 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. Its biological activity is essential for research applications in purine metabolism and nitrogenous waste elimination pathways in various organisms. -
Purine Nucleoside Analog
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in cancer research. Its mechanisms of action are essential for studies focused on developing novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
5’-Azido-5’-deoxyuridine is a purine nucleoside analog that exhibits potent antitumor activity, primarily targeting indolent lymphoid malignancies through mechanisms such as DNA synthesis inhibition and apoptosis induction. This compound serves as a valuable click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds containing DBCO or BCN functionalities, making it a versatile tool for bioconjugation applications in chemical biology and drug discovery. -
Purine Nucleoside Analog
2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mode of action involves the inhibition of DNA synthesis and the induction of apoptosis. This compound is utilized in various research applications aiming to explore therapeutic strategies in oncology and the mechanisms underlying cancer cell proliferation and survival. -
5’-AMP Analogue
6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP) that targets the 5’-AMP structure for chemical modification. This compound allows for selective modifications at position 6 using diverse nucleophiles, making it a valuable tool for researchers exploring nucleotide interactions and modifications. Its applications extend to studies in enzymatic processes and the development of modified nucleotides for therapeutic purposes. -
Purine Nucleoside Analog
2′-Chloro-2′-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in malignant cells, making it a valuable tool in cancer research and therapeutic applications. This compound is essential for studies aimed at understanding the effects of nucleotide analogs on cell proliferation and tumor development. -
Purine Nucleoside Analog
2-Amino-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mode of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on exploring therapeutic strategies for hematological cancers and understanding the mechanisms of nucleoside analogue efficacy. -
Purine Nucleoside Analog
5-Ethyl-4-thiouridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound is ideal for studies focused on understanding the effects of nucleoside analogs in tumor biology and therapeutic development. -
Purine Nucleoside Analog
3’-Deoxy-5-methoxyuridine is a purine nucleoside analog that primarily acts by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. It serves as a valuable tool for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
3'-Azido-3'-deoxyinosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. As a versatile click chemistry reagent, it features an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it useful for bioconjugation applications in chemical biology. -
Adenosine Analog
8-Benzyloxyadenosine is an adenosine analog that primarily targets adenosine receptors to elicit biological responses. This compound exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. It serves as a valuable tool for research in cardiovascular biology and cancer therapeutics. -
Purine Nucleoside Analog
5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine is a purine nucleoside analog that plays a crucial role in molecular biology research. This compound exhibits significant antitumor activity against indolent lymphoid malignancies, primarily through mechanisms that inhibit DNA synthesis and induce apoptosis. It serves as a valuable tool for studying cancer biology and developing potential therapeutic strategies aimed at lymphoid cancers. -
Nucleoside Metabolite
1β-Methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) is a nucleoside metabolite that serves as a seleno-containing analog of N-acetyl-D-galactosamine. It exhibits significant biological activity by participating in cellular methylation processes and potentially affecting selenoamino acid metabolism. This compound is utilized in studies focused on selenoprotein biology, nucleoside metabolism, and their implications in cancer and other diseases. -
Purine Nucleoside Analog
N6-Benzoyl-7'-OH-morpholino adenine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is utilized in studies exploring therapeutic strategies and the underlying biological processes in cancer progression. -
Adenosine Analog
5-Methyl-4’-thiouridine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant vasodilatory effects, promoting smooth muscle relaxation, and has shown potential in inhibiting cancer progression. Its applications in research encompass studies on cardiovascular function and cancer therapeutics. -
Purine Nucleoside Analog
2'-Deoxy-N2,N2-diethyl guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is essential for studies focused on the therapeutic potential of nucleoside analogs in oncology. -
Guanosine 5'-Phosphate
7-Methyl-guanosine-5'-triphosphate disodium is a modified guanosine 5'-phosphate that plays a critical role in cellular signaling and protein synthesis. As a potent cap-dependent translation inhibitor, it effectively disrupts the translation process by targeting the mRNA cap structure. This reagent is valuable for research applications exploring gene expression, translational regulation, and the mechanisms of RNA processing. -
Purine Nucleoside Analog
N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor properties. This compound primarily targets malignant lymphoid tissues, exerting its effects through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. It serves as a valuable tool for research applications focused on cancer therapeutics and the exploration of nucleoside analogs in oncological studies. -
Purine Nucleoside Analog
2’-O-(2-Methoxyethyl)-2-aminoadenosine functions as a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The underlying anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
2-(n-Propylidene hydrazino) adenosine is a purine nucleoside analog that exhibits significant antitumor activity, specifically against indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a useful tool in cancer research and therapeutic development. This compound supports studies focused on the mechanisms of cancer cell proliferation and survival. -
Purine Nucleoside Analog
2,6-Dichloro-9-(2-c-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine is a purine nucleoside analog that exerts its biological activity by interfering with DNA synthesis. This compound is noted for its broad-spectrum antitumor efficacy, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and other pathways critical for cancer cell proliferation suppression, making it a valuable tool for cancer research. -
Nucleoside Metabolite
Avenastenone is a nucleoside metabolite with significant implications in cellular metabolism. This compound exhibits potential biological activity by participating in nucleic acid synthesis and influencing metabolic pathways. It is valuable for research applications focused on understanding nucleotide metabolism and cellular proliferation mechanisms. -
Adenosine Analog
8-Bromo-5’-O-(4-cyanobenzyl)-2’,3’-di-O-isopropylidene adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory activity and has potential applications in cancer research due to its ability to inhibit cancer progression. Its structural modifications make it a valuable tool for studying adenosine signaling pathways in various biological systems. -
Purine Nucleoside Analog
N1-Methyl-5-methyl ara-uridine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. Its application in research includes studying potential therapeutic strategies for lymphoid cancers and examining the underlying mechanisms of nucleoside analog efficacy in tumor cell lines. -
Purine Nucleoside Analog
5-Furan-2-yl-2'-O-methyl uridine functions as a purine nucleoside analog with significant biological activity against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. Its potential applications in research include the investigation of cancer therapeutics and the study of nucleoside metabolism in various biological systems. -
Adenosine Analog
8-Azidoadenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator and exhibits potential anti-cancer properties. This compound serves as a versatile click chemistry reagent, featuring an azide group that allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized substrates, making it valuable for applications in bioconjugation and labeling studies in chemical biology research. -
Nucleoside Metabolite
Carbamic acid is a nucleoside metabolite involved in various biological processes. It plays a crucial role in the biosynthesis and metabolism of nucleotides, serving as an important intermediate. This compound is valuable for research applications related to nucleic acid chemistry and cellular signaling pathways. -
Purine Nucleoside Analog
4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects primarily involve inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research focused on the development and evaluation of novel antineoplastic agents. -
Purine Nucleoside Analog
2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutics. This compound can be utilized to investigate cellular responses to purine metabolism disruption and to explore novel treatment strategies for lymphoid malignancies. -
Thymidine Analog
5’-O-Acetyl-5-acetyloxymethyluridine is a thymidine analog that exhibits insertional activity in replicated DNA. This compound can be utilized to label cells, enabling the tracking of DNA synthesis and providing valuable insights into cellular proliferation and genomic stability. Its unique properties make it a useful tool in molecular biology and cancer research applications. -
Purine Nucleoside Analog
N6-Benzoyl-2'-chloro-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it valuable for research in cancer therapy. This compound serves as a critical tool for investigating the roles of purine metabolism and nucleoside signaling in oncogenesis. -
Purine Nucleoside Analog
9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog that exerts its biological activity by inhibiting DNA synthesis. This compound demonstrates broad antitumor effects, particularly against indolent lymphoid malignancies, through mechanisms such as the induction of apoptosis. It is a valuable reagent for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog known for its potent antitumor properties. This compound targets indolent lymphoid malignancies, exerting its effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research, aiding in the study of therapeutic strategies against various malignancies. -
Hypoxanthine Analog
6-O-Methylinosine is a hypoxanthine analogue that serves as a key metabolite in purine metabolism. It exhibits significant anti-inflammatory properties and has potential as an endogenous inhibitor of poly(ADP-ribose) polymerase (PARP), contributing to cytoprotection by preventing PARP activity. This compound also offers insights into cellular responses to hypoxia, making it valuable for research in cellular signaling and oxidative stress. -
Uridine Analog
3’-β-C-Ethynyluridine is a uridine analog that serves as an important tool in neurological research. It exhibits potential antiepileptic properties and is utilized to investigate anticonvulsant and anxiolytic activities, contributing to the development of novel antihypertensive agents. Additionally, due to its alkyne group, 3’-β-C-Ethynyluridine functions as a click chemistry reagent, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. -
Purine Nucleoside Analog
4’-Methyl-5-methyluridine is a purine nucleoside analog known for its antitumor properties. This compound exhibits significant activity against indolent lymphoid malignancies, primarily through the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research, contributing to studies focused on therapeutic strategies for lymphoid tumors.
