Fig. 1 · Structure

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8-Azidoadenosine

Adenosine Analog

8-Azidoadenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator and exhibits potential anti-cancer properties. This compound serves as a versatile click chemistry reagent, featuring an azide group that allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized substrates, making it valuable for applications in bioconjugation and labeling studies in chemical biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 4372-67-2
Applications Adenosine Analog
Formula C10H12N8O4
Molecular Weight 308.25
SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C(N=[N+]=[N-])=N2)C3=C2C(N)=NC=N3)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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