8-Azidoadenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator and exhibits potential anti-cancer properties. This compound serves as a versatile click chemistry reagent, featuring an azide group that allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized substrates, making it valuable for applications in bioconjugation and labeling studies in chemical biology research.
8-Azidoadenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator and exhibits potential anti-cancer properties. This compound serves as a versatile click chemistry reagent, featuring an azide group that allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized substrates, making it valuable for applications in bioconjugation and labeling studies in chemical biology research.
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