Catalog No.
Product Name
Application
Product Information
Citations
-
Guanosine Analog
N2-Phenoxyacetylguanosine is a guanosine analog that targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity and has been shown to induce type I interferons in animal models, resulting in antiviral effects. It serves as a valuable tool for research applications focused on viral infections and immune responses. -
Purine Nucleoside Analog
2'-Deoxy-N6-cyclopentyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is utilized in research applications aimed at understanding cancer biology and developing novel therapeutic strategies. -
Purine Nucleoside Analog
7-Methyl wyosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is utilized in research applications focused on cancer therapy and the study of nucleoside interactions within cellular processes. -
Uridine Analog
3’-O-(2-Methoxyethyl) uridine is a uridine analog that primarily targets the uridine metabolic pathway. This compound exhibits potential antiepileptic properties and serves as a valuable tool for researching anticonvulsant and anxiolytic activities. Additionally, it can be utilized in the development of new antihypertensive agents, facilitating advancements in therapeutic applications. -
Guanosine Analog
3,5-Bis-O-(2,4-dichlorobenzyl)guanosine is a guanosine analog targeting Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity, capable of inducing type I interferons and producing antiviral effects in various animal models. It serves as an essential tool for research focused on viral infections and immune response mechanisms. -
Purine Nucleoside Analog
2′-Deoxy-2-iodoadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications in cancer biology and therapeutic development targeting various malignancies. -
Purine Nucleoside Analog
8-Azaguanosine is a purine nucleoside analog that exhibits significant anticancer activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is utilized in research aimed at understanding and developing targeted therapies for various hematological malignancies. -
Thymidine Analog
5'-O-Benzoylthymidine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is utilized in various research applications, including the labeling of cells and tracking of DNA synthesis. Its ability to mimic natural thymidine positions it as a valuable tool for studies in molecular biology and genetics. -
Purine Nucleoside Analog
3’-O-MOE-A(Bz)-2’-CED-phosphoramidite is a purine nucleoside analog that impedes DNA synthesis and induces apoptosis, making it a valuable tool in cancer research. This compound exhibits significant antitumor activity against indolent lymphoid malignancies, facilitating studies on mechanisms of tumor growth inhibition. It is suitable for applications in the development of therapeutic strategies and understanding purine metabolism in cancer cells. -
Purine Nucleoside Analog
3',5'-Di-O-acetylthymidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research into cancer therapeutics and the modulation of nucleoside metabolism in cancer cells. -
Purine Nucleoside Analog
3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analog with potent antitumor activity. This compound primarily targets indolent lymphoid malignancies through mechanisms that include the inhibition of DNA synthesis and the induction of apoptosis. It is a valuable tool for researchers investigating cancer biology and therapeutic strategies in oncology. -
Purine Nucleoside Analog
N2-iso-Butyroyl-2'-fluoro-2'-deoxyarabinoguanosine is a purine nucleoside analog that exerts antitumor activity primarily against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of nucleoside analogs in various cancer models. -
Thymidine Analog
5-Naphthyl-beta-methylaminocarbony-2'-O-methyluridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is valuable for labeling cells and facilitating the tracking of DNA synthesis in various biological research applications. Its structural similarity to thymidine enables its utilization in studies involving nucleic acid metabolism and cellular proliferation. -
Purine Nucleoside Analog
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog that acts as a potent inhibitor of DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleotide incorporation during DNA replication. This compound is essential for research into cancer therapeutics and the development of novel DNA-targeting strategies. -
Purine Nucleoside Analog
2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue known for its antitumor properties. This compound exhibits significant activity against indolent lymphoid malignancies, primarily through the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. It is a valuable tool for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
3’-Deoxy-2’-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily targets indolent lymphoid malignancies through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. It is a valuable reagent for researchers investigating cancer biology and therapeutic strategies targeting nucleoside metabolism. -
Adenosine Analog
N6-(3-Trifluoromethylbenzyl)-2’-C-methyl adenosine is an adenosine analog that primarily acts on adenosine receptors. This compound demonstrates smooth muscle vasodilatory properties and has potential applications in inhibiting cancer progression. Its structural modifications enhance its affinity and selectivity, making it a valuable reagent for research in vascular biology and oncology. -
Purine Nucleoside Analog
6-(2-Furanyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer therapeutics and the study of nucleoside metabolism. -
Purine Nucleoside Analog
5’-Deoxy-5’-(4-morpholinyl)thymidine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly in indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized to explore therapeutic strategies and uncover insights into the molecular mechanisms of tumor growth and response to treatment. -
Purine Nucleoside Analog
2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog that demonstrates significant antitumor activity by targeting indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding its effects on cellular proliferation and tumorigenesis. -
Adenosine Analog
N6,N6-Dimethyl-xylo-adenosine is an adenosine analog with a primary mechanism of action involving modulation of adenosine receptors. This compound has demonstrated significant smooth muscle vasodilator activity and holds potential in inhibiting cancer progression. It is widely utilized in research applications focusing on vascular biology and oncology. -
Uridine Analog
N3-Methyl-2’-O-(2-methoxyethyl)uridine is a uridine analog that acts as a competitive inhibitor of uridine metabolism. This compound exhibits potential antiepileptic properties and is utilized in research to investigate anticonvulsant and anxiolytic activities. Additionally, it is a valuable tool for the development of novel antihypertensive agents. -
Purine Nucleoside Analog
3'-Deoxy-3'-fluoro-5-fluorouridine is a purine nucleoside analog known for its potent antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its application in cancer research aids in elucidating mechanisms of tumor cell proliferation and survival, contributing to the development of novel therapeutic strategies. -
Purine Nucleoside Analog
2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent due to the presence of an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, facilitating various bioconjugation applications in chemical biology. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-methoxy uridine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is suitable for studies focused on nucleoside metabolism and anticancer therapeutics. -
Purine Nucleoside Analog
5’-O-DMTr-3’-deoxyuridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. This compound can be utilized to investigate the pathways involved in tumor growth and resistance, providing insights into potential treatment strategies. -
Purine Nucleoside Analog
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and the development of therapeutic strategies targeting nucleic acid metabolism. -
Purine Nucleoside Analog
2′,3′-O-Isopropylideneisocytidine is a purine nucleoside analog that exerts significant antitumor activity by targeting indolent lymphoid malignancies. This compound primarily functions through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. Its unique mechanism highlights its potential in various therapeutic applications aimed at treating specific types of malignancies. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies, and induces apoptosis in cancer cells. Its applications in research provide valuable insights into the mechanisms of cancer treatment and therapeutic resistance. -
Purine Nucleoside Analog
2’-Amino-2’-deoxy-5-methyl uridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound offers potential for exploring therapeutic strategies in oncology and advancing the understanding of nucleoside analog effects in tumor biology. -
Guanosine Analog
N1,N2-Dimethyl-2'-O-methylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). It exhibits immunostimulatory activity and has been shown to induce type I interferons in various animal models, leading to significant antiviral effects. This compound is valuable in research applications focused on immune response modulation and the study of viral infections. -
Nucleoside Metabolite
22-Oxodocosanoic acid is a nucleoside metabolite that plays a critical role in cellular metabolism. It is involved in the regulation of fatty acid metabolism and may influence various biological processes such as cell signaling and energy homeostasis. This compound is suitable for research applications focusing on metabolic pathways and the study of nucleoside-related biological activities. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analog known for its potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound features an azide group, making it suitable for click chemistry applications, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules, as well as DBCO or BCN groups. -
Nucleoside Metabolite
5-Hydroxykynurenine is a nucleoside metabolite that primarily functions as a precursor in the kynurenine pathway, influencing the balance of neuroactive metabolites. This compound exhibits bioactivity related to neuroprotection and modulation of neurotransmitter systems. It is commonly utilized in research focused on neurodegenerative diseases, psychiatric disorders, and inflammation studies, making it valuable for understanding neurochemical mechanisms. -
Purine Nucleoside Analog
2-Bromoadenosine is a purine nucleoside analog that exhibits potential antimalarial and anticancer activities. It is known to target indolent lymphoid malignancies through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. This compound is relevant for research applications focused on cancer therapy and elucidating the effects of purine analogs in cellular processes. -
Adenosine Analog
5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is an adenosine analog known for its role as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable in various research applications related to cardiovascular health and oncology. Its structural properties allow for incorporation into oligonucleotides, facilitating studies on adenosine signaling pathways and therapeutic development. -
Antitumor Compound
LY207702 is a difluorinated purine nucleoside that exhibits antitumor activity primarily through cytotoxic effects on cancer cells. It demonstrates significant cytotoxicity against CEA-positive LS174T cells, with an IC50 value of 0.302 μg/mL. This compound is valuable for research applications in colon cancer studies, contributing to the understanding of therapeutic mechanisms and potential treatment strategies. -
Nucleoside Metabolite
(25S)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA is a nucleoside metabolite that plays a crucial role in lipid metabolism. This compound may participate in various biochemical pathways and can be utilized in research focused on cholesterol metabolism and related diseases. Its structural features suggest potential implications in studies of lipid biochemistry and cellular signaling. -
Purine Nucleoside Analog
2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting apoptosis and disrupting cellular proliferation. It serves as a valuable tool in cancer research, aiding in the understanding of therapeutic mechanisms and the development of novel treatments. -
Nucleoside Antimetabolite/Analog
Thiamiprine is a nucleoside antimetabolite and analog related to azathioprine, primarily targeting DNA synthesis. This compound exhibits cytotoxic effects in vitro, demonstrating activity comparable to its parent compound, though its arabinoside variant is inactive and non-toxic. In vivo studies using the rat adjuvant arthritis model indicate that the riboside and 2'-deoxyriboside forms are less active than the parent compound, while maintaining a distinct safety profile. Thiamiprine is valuable for research applications focused on immunosuppression and cellular proliferation. -
Purine Nucleoside Analog
9-(2-β-C-Methyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that exerts its effects by targeting cellular pathways involved in DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. It serves as a valuable tool for research applications in cancer biology and therapeutics development. -
Purine Nucleoside Analog
7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its biological activity includes inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized to study mechanisms of cancer cell proliferation and therapeutic resistance, contributing to the development of targeted cancer therapies. -
Purine Nucleoside Analog
3'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, particularly in studying cell proliferation and the apoptotic pathways in lymphoid malignancies. -
Purine Nucleoside Analog
2-Trifluoromethyl adenosine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Cytidine Analog
2',3',5'-Tri-O-benzoyl-5-azacytidine serves as a potent cytidine analog with a primary mechanism of inhibiting DNA methyltransferases. This compound demonstrates significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research and epigenetic studies. Its ability to interfere with DNA methylation processes positions it as an important reagent for investigating gene expression regulation and therapeutic interventions in oncology. -
Unsaponifiable Lipid
4α-Methylfecosterol is an unsaponifiable lipid that serves as a critical component in lipid metabolism studies. This compound exhibits unique biological activity by influencing membrane fluidity and cellular signaling pathways. It is valuable for research applications in lipid biochemistry, endocrinology, and the study of metabolic disorders. -
Thymidine Analog
5-(Hydroxymethyl)-2′,3′-O-(1-methylethylidene)uridine is a thymidine analog that integrates into replicated DNA. This compound demonstrates insertional activity, making it valuable for cell labeling and monitoring DNA synthesis. Its applications extend to research focusing on cellular proliferation and genetic analysis. -
Cytidine Analog
5-Methoxy cytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research and epigenetics studies. Its unique properties enable investigations into the regulatory roles of DNA methylation in various biological processes and diseases. -
Nucleoside Analogue
1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nucleoside analogue targeting cellular enzymatic pathways. This compound exhibits potential antiviral and anticancer activity, making it a valuable tool for researchers studying nucleoside metabolism and related therapeutic applications. Its unique structural modifications enhance its stability and efficacy in various biological systems, facilitating investigations into nucleoside function and biochemistry. -
Purine Nucleoside Analog
3',4-Dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic interventions targeting nucleoside metabolism.
