5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog that acts as a potent inhibitor of DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleotide incorporation during DNA replication. This compound is essential for research into cancer therapeutics and the development of novel DNA-targeting strategies.
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog that acts as a potent inhibitor of DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleotide incorporation during DNA replication. This compound is essential for research into cancer therapeutics and the development of novel DNA-targeting strategies.
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