Fig. 1 · Structure

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2′,3′-Dideoxy-5-fluorouridine

Purine Nucleoside Analog

2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting apoptosis and disrupting cellular proliferation. It serves as a valuable tool in cancer research, aiding in the understanding of therapeutic mechanisms and the development of novel treatments.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 15379-30-3
Applications Purine Nucleoside Analog
Formula C9H11FN2O4
Molecular Weight 230.19
SMILES
OC[C@@H]1CC[C@H](N2C(NC(C(F)=C2)=O)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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