Fig. 1 · Structure
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LY207702
Antitumor Compound
LY207702 is a difluorinated purine nucleoside that exhibits antitumor activity primarily through cytotoxic effects on cancer cells. It demonstrates significant cytotoxicity against CEA-positive LS174T cells, with an IC50 value of 0.302 μg/mL. This compound is valuable for research applications in colon cancer studies, contributing to the understanding of therapeutic mechanisms and potential treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 103828-81-5 |
| Applications | Antitumor Compound |
| Formula | C10H12F2N6O3 |
| Molecular Weight | 302.24 |
| SMILES | NC1=C2NC(C3C(F)([C@H](O)[C@H](O3)CO)F)=NC2=NC(N)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.