Catalog No.
Product Name
Application
Product Information
Citations
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Dye
Carmine lithium is a natural red colorant derived from cochineal insects, classified within the coccid dye family. It is widely utilized in histological staining and as a biological marker due to its strong affinity for proteins and tissues. This reagent is essential for various research applications, including microscopy and cell imaging, enabling detailed visualization of biological samples. -
Fluorescent Dye
BP Fluor 430 DBCO is a fluorescent dye that reacts with azides through a copper-free click chemistry mechanism, resulting in stable triazole formations without the need for copper catalysts or elevated temperatures. This dye exhibits bright, photostable green fluorescence, with optimal excitation at 432 nm and an emission peak at 539 nm, remaining pH independent across a broad pH range. BP Fluor 430 DBCO is suitable for various labeling applications in bioimaging and bioconjugation, although it is not recommended for staining intracellular components of fixed and permeabilized cells due to potential high background fluorescence. -
Fluorescent Dye
BP Fluor 405 Picolyl Azide is a fluorescent dye designed for enhanced detection in bioconjugation reactions, utilizing a copper-chelating motif to increase local Cu(I) concentrations. This innovative reagent significantly accelerates the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction rate while minimizing the required copper catalyst concentration by at least tenfold. The incorporation of the picolyl azide moiety allows for greater sensitivity in alkyne detection, making it particularly advantageous for applications involving low-abundance targets or those requiring amplified signal intensity. This makes BP Fluor 405 an essential tool for researchers focusing on advanced fluorescent labeling techniques. -
Dye
Direct Brown 95 is a synthetic dye primarily utilized for coloring fabrics in the textile industry. Its applications extend to histology and cytology, where it aids in the differentiation of various cell types. Moreover, this dye serves as a molecular marker, enhancing the detection of nucleic acids such as DNA and RNA in laboratory analyses. -
Fluorescent Probe
Fluoresterol (22-NBD Cholesterol) is a cholesterol-specific fluorescent probe designed to bind selectively to cholesterol transport-related proteins, including ABCA1 and ABCG1. This compound serves as a valuable tool for studying cholesterol metabolism, enabling visualization and quantitative analysis of cholesterol absorption, efflux, intracellular transport dynamics, and reverse cholesterol transport processes. Fluoresterol is particularly useful in research exploring the mechanisms underlying hyperlipidemia, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). Common application concentrations range from 0.1 to 10 μM in vitro and doses of 5 to 20 mg/kg for in vivo studies, with excitation and emission wavelengths of 472 nm and 540 nm, respectively. -
Fluorescent Dye
Sulfo-Cy5-Mal is a reactive fluorescent dye designed to covalently label proteins via thiol groups, forming stable conjugates. This dye is ideal for applications requiring sensitive detection, quantification, and imaging of proteins in various biological assays. Its strong fluorescence enables high-resolution analyses in immunofluorescence, flow cytometry, and multiplexing experiments, facilitating advanced protein research. -
Fluorescent Dye
SBP-3264 is a fluorescent dye that serves as a valuable chemical probe for investigating the roles of STK3 and STK4 kinases in acute myeloid leukemia (AML). This compound is specifically designed to aid in the analysis of cellular signaling pathways and can enhance understanding of AML pathogenesis. Its unique fluorescent properties enable effective visualization and tracking in various research applications related to cancer biology. -
Fluorescent Dyes
ICG-DBCO is a near-infrared fluorescent dye targeting biological imaging applications. Its fluorescence emits at 813 nm upon excitation at 789 nm, making it suitable for labeling cells, biomolecules, and particles. This compound is essential for various research applications, including in vivo imaging and fluorescence microscopy, allowing for enhanced visualization of biological processes. -
Fluorescent Dye
SBB-Analogue (GL13) Biotin is a fluorescent dye derived from Sudan Black B, conjugated to biotin. This reagent specifically detects senescent cells, overcoming the false positive staining issues associated with SA-β-gal due to factors such as serum starvation and cell confluency. SBB-Analogue (GL13) Biotin is suitable for applications in flow cytometry and immunofluorescence analysis, providing a reliable tool for studying cellular senescence in various biological contexts. -
Azo Dye
Methyl red is an azo dye that functions as a pH-sensitive acid-base indicator with a pKa of 5.1. It facilitates visual determination of titration endpoints by undergoing reversible structural changes related to protonation (red at pH <4.4) and deprotonation (yellow at pH >6.2). Methyl red is extensively utilized in acid-base titrations and for monitoring buffer pH in biochemical research. -
Fluorescent probe
Coppersensor-3 is a highly selective fluorescent probe designed for the detection of Cu(I) ions. With its robust sensitivity, Coppersensor-3 enables the imaging of labile copper pools within living cells at endogenous levels. This reagent is ideal for investigations into copper's biological roles and dynamics in cell biology research. -
Fluorescent Probe
8-Hydroxyjulolidine-9-carboxaldehyde is a selective fluorescent probe targeting hydrogen sulfide (H2S) and silicate (SiO32−). This compound functions through the inhibition of intramolecular charge transfer (ICT), resulting in significant fluorescence enhancement upon interaction with weak acid ions. It is particularly valuable for research applications involving fluorescence imaging of hydrogen sulfide in living cells, providing insights into biological processes associated with this important signaling molecule. -
Fluorescent Dye
NBD-Fructose is a fluorescent derivative of fructose, created through the coupling of NBD-chloride with the amino group of fructose. It exhibits fluorescence with excitation and emission maxima at 472 nm and 538 nm, respectively. This reagent is primarily utilized in biological assays to study carbohydrate metabolism and transport, providing a valuable tool in research involving cellular imaging and detection of fructose in various biological samples. -
Amine-reactive Fluorescent Probe
Rhodamine B NHS ester is an amine-reactive fluorescent probe that efficiently labels amine-containing biomolecules. With excitation and emission wavelengths of 564 nm and 589 nm, respectively, it is widely utilized in various biological applications, including protein tagging and cellular imaging. This reagent can specifically react with primary amines, enabling researchers to study protein interactions and localization in live cells and complex biological systems. -
Fluorescent Dye
Alexa Fluor 594 azide is a fluorescent dye modified with an azide group, functioning as a FRET acceptor. Its minimal direct absorption under 488 nm excitation ensures excellent photostability and compatibility with various donor dyes, making it suitable for single-molecule imaging applications using total internal reflection fluorescence microscopy (TIRFM). This reagent is particularly valuable for visualizing copper nanoparticle-catalyzed click reactions, facilitating detailed studies of reaction dynamics and mechanisms. -
Fluorescent Dye
FAM DBCO, 6-isomer is a fluorescent dye that incorporates a terminal dibenzocyclooctyne (DBCO) group, allowing for copper-free Click Chemistry applications. This compound exhibits high reactivity due to its strained structure, facilitating the efficient formation of covalent bonds in bioconjugation reactions. FAM DBCO can be utilized in a variety of biological applications, including cell labeling, tracking, and imaging studies. -
Fluorescent Dyes
BODIPY-Palmitate is a fluorescently labeled derivative of palmitic acid, exhibiting excitation and emission maxima at 488 nm and 508 nm, respectively. This reagent is utilized for the detection of fatty acid uptake and metabolism in various biological systems. Its fluorescent properties make it an effective tool for studying lipid dynamics and cellular fatty acid processing in live-cell imaging studies. -
Fluorescent Probe
8-Amino-2-naphthol functions as a fluorescent probe through its unique photoactive charge transfer properties. Under acidic conditions, it undergoes excited-state proton transfer (ESPT) to form a zwitterion, allowing the protonation state of the amino group to modulate the photoacidity of its hydroxyl group, effectively enabling pH-dependent fluorescence. Additionally, this compound serves as a chiral organocatalyst in various organic synthesis applications. -
Fluorescent Dye
Tamra azide is a versatile, azide-terminated fluorescent dye utilized primarily in click chemistry applications. It participates in CuI-catalyzed cycloaddition reactions with alkyne-functionalized nanodiamonds, enabling stable conjugation. Once attached, Tamra azide acts as a fluorescent label, exhibiting characteristic luminescence when excited at a wavelength of 555 nm with emission at 580 nm. This compound is valuable for a variety of imaging and labeling applications in chemical biology and materials science. -
Fluorescent Dye
FAM azide, 5-isomer is a fluorescent dye commonly used in Click Chemistry for bioconjugation applications. This compound facilitates the labeling of biomolecules with minimal cytotoxicity, enhancing the visualization of cellular structures and processes. Its high fluorescence intensity makes it suitable for various applications, including live-cell imaging, biomolecule tracking, and the development of fluorescent probes in research and diagnostic assays. -
Fluorescent Labeling Reagent
9-Aminophenanthrene is a polycyclic aromatic amine utilized primarily as a fluorescent labeling reagent for free fatty acids (FFA). This compound exhibits notable fluorescence properties, enabling the detection and analysis of fatty acids in various biological samples. Its application is essential in research focused on lipid metabolism and fatty acid signaling pathways. -
Fluorescent Substrate
4-Methylumbelliferyl β-D-cellobioside is a fluorescent substrate specifically designed for the enzymatic study of cellulase activity. It undergoes hydrolysis, producing the fluorescent compound 4-methylumbelliferone, which serves as a valuable indicator for quantifying cellulase kinetics. This reagent is particularly useful in biochemical assays for investigating cellulose degradation and enzyme kinetics in cellulolytic microorganisms. -
Fluorescent Dye
2,4,6-Trimethylphenol functions primarily as a fluorescent dye and exhibits reactivity with organic matter (3DOM). This compound is rapidly oxidized by singlet oxygen in aqueous solutions, making it a valuable tool for studying oxidative processes in biological systems and environmental research. It is effectively utilized in applications involving fluorescence-based detection and analysis. -
Fluorescent Probe Chromophore
8-Hydroxyjulolidine is a chromophore that serves as a key component in fluorescent probes designed for detecting weak acid ions. This compound can be utilized to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which demonstrates a high sensitivity for detecting pH changes related to hydrogen sulfide and silicate in aqueous solutions. The versatility of 8-Hydroxyjulolidine makes it valuable in a variety of chemical research applications involving acid-base interactions. -
Biological Dye
Acid Blue 1, known as Patent Blue V, serves as a biological dye primarily utilized in intraocular procedures such as retinectomy, where the inner limiting membrane (ILM) is removed. Its application facilitates the complete removal of translucent structures during vitreoretinal surgery by effectively staining retinal premembranous components. Spectral analysis indicates strong absorption below 450 nm and above 600 nm, resulting in its distinctive blue-green coloration. Additionally, Acid Blue 1 is employed as a marker in lymphangiography to aid in the resection of neoplastic lymph nodes, thereby enhancing surgical precision in oncological applications. -
Laser Dye
Coumarin 480, a laser dye, exhibits strong fluorescence properties, making it suitable for applications in fluorescence microscopy and spectroscopy. Its high quantum yield and stability under various conditions make it a valuable reagent for studying biomolecular interactions and cellular dynamics. Coumarin 480 is often utilized in dye-laser systems and as a tracer in various experimental setups in chemical and biological research. -
Fluorescence Dye
(E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide is a styryl-based fluorescence dye that emits light upon excitation. With an absorption maximum at 450 nm and emission maximum at 615 nm, this compound is effective for fluorescence and circular dichroism sensing of diverse double-stranded DNA and RNA sequences. It is a valuable tool in nucleic acid research and clinical diagnostics, facilitating the study of biomolecular interactions and structures. -
Fluorescent Probe
Coumarin 343 is a hydrophilic fluorescent probe primarily used for micro water pool applications. It exhibits strong fluorescence with an emission wavelength (λem) of approximately 425 nm and can be detected in the range of 425 nm to 550 nm. This compound is suitable for various biological imaging and analytical techniques, providing insights into molecular interactions and cellular processes. -
Phosphatidylserine-binding Fluorescent Probe
APO-15 is a phosphatidylserine-binding fluorescent probe designed for apoptosis imaging. This reagent demonstrates exceptional chemical stability in both proteolytic and oxidative environments, facilitating the quantification and visualization of drug-induced apoptosis in preclinical mouse models, as well as fixed tissue samples. With an excitation wavelength of 488 nm and emission at 525 nm, APO-15 is particularly valuable in research focusing on acute lung injury and breast cancer. -
Fluorescent Lipid
C11 BODIPY 505/515 MG is a fluorescently labeled glycerolipid with an excitation/emission wavelength of 495/503 nm. This compound enables the visualization and tracking of lipid dynamics in biological systems. It is widely utilized in cell biology and biochemistry for studying membrane composition and lipid metabolism. -
H2O2 Fluorescent Probe
Pentafluorobenzenesulfonyl fluorescein is a selective fluorescent probe designed for the detection of hydrogen peroxide (H2O2) within cellular environments. This compound exhibits minimal fluorescence in its native state, becoming markedly fluorescent upon cleavage of the sulfonyl linkage by H2O2. Its specific reactivity allows for effective monitoring of oxidative stress and related biological processes, making it a valuable tool for research in cell biology and redox signaling pathways. -
Light-Activated Fluorescent Probe
PA-JF549-Halo ligand is a photoactivatable fluorescent probe designed for targeting the HaloTag protein. Featuring the bright and photostable JF549 dye, this conjugate has intrinsic properties that facilitate localization to mitochondria, enhancing imaging quality. PA-JF549-Halo ligand is ideal for high-resolution single-molecule and super-resolution imaging of specific proteins in live cells, supporting applications in cellular and molecular biology research. -
Dye
Quinophthalone is a synthetic dye known for its distinctive greenish-yellow coloration. It functions as a coloring agent for a variety of materials, emphasizing its versatility in applications such as textiles and plastics. Additionally, Quinophthalone demonstrates strong sensitizing properties in guinea pigs, with a threshold concentration for induction and challenge established at 10 ppm, highlighting its potential implications in toxicological studies and safety assessments. -
Iron Dye Reagent
Ferrozine sodium hydrate is an iron dye reagent that selectively binds to divalent iron ions (Fe²⁺), forming a stable magenta complex. This complex exhibits a strong absorption peak at 562 nm, making it suitable for spectrophotometric analysis. Ferrozine sodium hydrate is widely employed in colorimetric assays to quantify iron levels in biological samples, providing essential data for studies on iron metabolism and related disorders. -
Calcium Deposits Dye
Alizarin Red S is an anthraquinone derivative dye primarily utilized for visualizing calcium deposits. It forms a coordination bond with calcium ions, resulting in an orange-red fluorescence, making it useful for detecting osteoblast differentiation and screening calcium compounds in synovial fluid. This reagent is also commonly employed for bone staining in murine models. The excitation and emission wavelengths are 500 nm and 570 nm, respectively. -
Fluorescent Dye
Acridinium C2 NHS ester is a fluorescent dye that functions as a chemiluminescent label, specifically designed for the development of protein and nucleic acid probes. This reagent enables highly sensitive detection solutions, making it valuable in bioanalysis and diagnostics. Its broad applications in medical research, particularly in the monitoring and analysis of biomolecules, underscore its significance in advancing scientific studies. -
Complexometric Indicator Dye
Catechol violet is a complexometric indicator dye known for its versatility as a ligand in Cu(I)-catalyzed C-S coupling reactions. Its ability to form stable complexes makes it valuable in various analytical applications, allowing for the detection and quantification of metal ions in solution. This reagent is essential for researchers investigating metal-mediated reactions and complexation phenomena in chemical studies. -
Fluorescent Peptide Substrate
Suc-Leu-Tyr-AMC is a fluorescent peptide substrate designed specifically for µ-calpain and m-calpain enzymes. It is characterized by an excitation wavelength of 360 nm and an emission wavelength of 460 nm, making it suitable for fluorescence-based assays. This reagent serves as a vital tool in studying calpain activity and related biological processes. Its application in research can aid in the understanding of proteolytic cleavage and its implications in various physiological and pathological conditions. -
Fluorescent Dye
H-Asp(AMC)-OH is an amino acid derivative functioning as a fluorescent dye that is widely used in biochemical assays. This compound exhibits significant fluorescence properties, making it an excellent tool for studying protein interactions and enzyme activities. Importantly, H-Asp(AMC)-OH does not inhibit glycine transport at concentrations up to 0.25 mM, ensuring minimal interference in transport studies. Its applications include fluorescence microscopy and various biochemical assays that require sensitive detection of biomolecules. -
Caspase-1/11 Fluorescent Substrate
Ac-YEVD-AMC is a fluorescent substrate specifically designed for the detection of caspase-1 and caspase-11 activity. Upon hydrolysis by these caspases, Ac-YEVD-AMC releases the fluorescent compound amino-4-methylcoumarin (AMC), enabling real-time monitoring of caspase activation in various biological assays. This reagent is suitable for research applications focused on inflammation, apoptosis, and other signaling pathways mediated by caspase activity. -
Fluorescent Dye
Solvent Green 3 is an anthraquinone-based fluorescent dye that targets biological samples for imaging applications. This dye exhibits strong fluorescence under UV light, making it suitable for the staining of cells, bacteria, and tissue samples in microscopy studies. Solvent Green 3 is particularly useful in biological research for visualizing cellular structures and processes, allowing for enhanced clarity in experimental analysis. -
Fluorescent peptide substrate
H-GLU-AMC-OH is a fluorescent peptide substrate specifically designed for the assessment of aminopeptidase A enzyme activity. This compound enables sensitive quantification and observation of enzyme kinetics in various biological samples. Its application is beneficial in studies involving peptide metabolism and enzyme regulation, providing valuable insights into aminotransferase functions. -
Fluorescent Dye
(Z-Ala-Ala-Ala-Ala)2Rh110 is a fluorogenic elastase substrate that exhibits high sensitivity. Initially colorless and nonfluorescent, this compound is specifically cleaved by elastase, resulting in the production of the fluorescent rhodamine 110, which can be effectively measured at an excitation wavelength of 485 nm and an emission wavelength of 525 nm. This substrate is valuable for studying elastase activity and can be applied in various biochemical assays and research applications focused on protease activity. -
Fluorescent Dye
Pantothenate-AMC is a fluorogenic substrate specifically designed for the detection of vanin-1 enzymatic activity, which plays a crucial role in L-pantothenic acid recycling. Upon cleavage by vanin-1, the substrate releases 7-amino-7-methylcoumarin (AMC), resulting in fluorescence that can be quantitatively measured. With excitation and emission maxima at 340-360 nm and 440-460 nm, respectively, Pantothenate-AMC is a valuable tool for research applications focused on enzymatic assays and metabolic studies. -
Fluorescent Dye
Cy3B maleimide is a mono-reactive fluorescent dye that targets thiol groups, enabling the selective conjugation of the Cyanine3B fluorophore to proteins and peptides with cysteine residues, as well as to other thiolated compounds, including thiol-containing oligonucleotides. This dye exhibits enhanced fluorescence quantum yield and superior photostability compared to traditional Cy3 dyes, making it an excellent choice for applications in fluorescence microscopy, flow cytometry, and various labeling studies in biochemical research. The versatility and efficiency of Cy3B maleimide offer valuable tools for studying protein interactions and intracellular processes. -
Fluorescent Probe
2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe that functions by integrating into oligodeoxyribonucleic acid as a nucleotide replacement. This compound exhibits significant utility in monitoring polar changes within tumor microenvironments, thereby aiding in cancer research. Its application as a DNA probe facilitates the study of nucleic acid dynamics and cellular responses, making it invaluable for researchers exploring tumor biology and related fields. -
Fluorescent Dye
LysoFP-NO2 is a turn-on fluorescent probe specifically designed for the detection of carbon monoxide (CO) in lysosomal compartments. Upon interaction with lysosomal CO, LysoFP-NO2 is converted to the highly fluorescent LysoFP-NH2, enabling enhanced detection capabilities. This probe exhibits remarkable selectivity for CO, distinguishing it from various reactive nitrogen, oxygen, and sulfur species. It has excitation and emission maxima at 440 nm and 528 nm, respectively, and demonstrates low cytotoxicity in HepG2 cells at a concentration of 30 μM for up to five hours, making it suitable for various cellular imaging applications. -
Fluorescent Core Scaffold
Cyanine is a versatile fluorescent core scaffold that serves as a foundation for the development of fluorescent probes. Its ability to undergo covalent conjugation with various potent compounds enhances their efficacy and broadens their application potential. Cyanine is particularly valuable in the advancement of theranostic agents for cancer treatment and is widely utilized in cancer research for imaging and diagnostic purposes. -
Photoinitiator/Fluorescent Whitening Agent
Fluorescent Brightener 28 is a fluorescent whitening agent and photoinitiator that enhances brightness in textile applications. It effectively stains polysaccharides like cellulose, weakly labeling the cytoplasm and intensely marking the cell nucleus upon plasma membrane disruption. This compound is also employed for detecting intracellular chitin within living cells and serves as a light-sensitive photoinitiator for free radical photopolymerizations using visible LED light. Its versatile applications make it a valuable tool in both biological research and material science. -
Fluorescent Dye
NIR-641 N-succinimidyl ester bromide is a fluorescent dye that primarily targets amine groups for conjugation in biomolecular studies. It exhibits high sensitivity and stability, making it suitable for a variety of imaging applications. This reagent is particularly valuable for visualizing cellular processes, assessing gene expression, and enhancing detection in various fluorescence-based assays.
