DNS-pE is a vinyl sulfone-based fluorescent dye designed to selectively label 3-phosphoglycerate dehydrogenase (PHGDH) in living mammalian cells. Upon labeling, it generates fluorescence, enabling real-time visualization of enzyme activity. In addition to its labeling capabilities, DNS-pE exhibits inhibitory properties akin to established inhibitors, making it a valuable tool for studying metabolic pathways and enzyme kinetics in biological research.
DNS-pE is a vinyl sulfone-based fluorescent dye designed to selectively label 3-phosphoglycerate dehydrogenase (PHGDH) in living mammalian cells. Upon labeling, it generates fluorescence, enabling real-time visualization of enzyme activity. In addition to its labeling capabilities, DNS-pE exhibits inhibitory properties akin to established inhibitors, making it a valuable tool for studying metabolic pathways and enzyme kinetics in biological research.
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