Nalidixic Acid-d5 is a deuterium-labeled derivative of nalidixic acid, a quinolone antibiotic that targets DNA gyrase and topoisomerase IV. This compound exhibits bacteriostatic activity at lower concentrations and demonstrates bactericidal effects at higher concentrations against a broad spectrum of gram-positive and gram-negative bacteria. Nalidixic Acid-d5 is utilized in research applications involving antibiotic resistance studies, bacterial DNA replication mechanisms, and pharmacokinetic investigations.
Nalidixic Acid-d5 is a deuterium-labeled derivative of nalidixic acid, a quinolone antibiotic that targets DNA gyrase and topoisomerase IV. This compound exhibits bacteriostatic activity at lower concentrations and demonstrates bactericidal effects at higher concentrations against a broad spectrum of gram-positive and gram-negative bacteria. Nalidixic Acid-d5 is utilized in research applications involving antibiotic resistance studies, bacterial DNA replication mechanisms, and pharmacokinetic investigations.
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